acc0001 |
Ku70 |
acetylation |
unclear |
human |
lung cancer |
H358 |
gefitinib |
promote |
5.0 |
19826407 |
acc0002 |
Ku70 |
acetylation |
unclear |
human |
lung cancer |
H358 |
gefitinib + Vorinostat |
promote |
5.0 |
19826407 |
acc0003 |
EGFR |
acetylation |
Lys1037 |
human |
colorectalcancer |
HT29 |
Sulfiredoxin |
modulate |
3.0 |
26290602 |
acc0004 |
P53 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
SMMC-7721 |
pterostilbene |
activate |
5.0 |
29042910 |
acc0005 |
PTEN |
acetylation |
unclear |
human |
hepatocellular carcinoma |
SMMC-7721 |
pterostilbene |
modulate |
4.0 |
29635894 |
acc0006 |
c-Jun |
acetylation |
unclear |
human |
skin cancer |
A431 |
ginsenoside Rg3 |
modulate |
4.0 |
31192452 |
acc0007 |
c-Jun |
acetylation |
unclear |
human |
skin cancer |
SCC12 |
ginsenoside Rg3 |
modulate |
4.0 |
31192452 |
acc0008 |
alpha-tubulin |
acetylation |
unclear |
human |
lung cancer |
A549 |
paclitaxel |
increase |
5.0 |
32580047 |
acc0009 |
alpha-tubulin |
acetylation |
unclear |
human |
cervical cancer |
HeLa |
paclitaxel |
increase |
5.0 |
32580047 |
acc0010 |
PVT1 H4 |
acetylation |
unclear |
human |
pancreas cancer |
PANC-1 |
gemcitabine |
promote |
4.0 |
34564701 |
acc0011 |
PVT1 H4 |
acetylation |
unclear |
human |
pancreas cancer |
BxPC-3 |
gemcitabine |
promote |
4.0 |
34564701 |
acc0012 |
PVT1 H4 |
acetylation |
unclear |
human |
pancreas cancer |
MIA PaCa-2 |
gemcitabine |
promote |
4.0 |
34564701 |
acc0013 |
METTL3 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
sulfatide |
modulate |
4.0 |
36149370 |
acc0014 |
METTL3 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
Hep3B |
sulfatide |
modulate |
4.0 |
36149370 |
acc0015 |
METTL3 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
SMMC-7721 |
sulfatide |
modulate |
4.0 |
36149370 |
acc0016 |
Rb |
phosphorylation |
Ser807 |
human |
pancreas cancer |
CAPAN1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0017 |
Rb |
phosphorylation |
Ser807 |
human |
pancreas cancer |
CFPAC-1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0018 |
Rb |
phosphorylation |
Ser811 |
human |
pancreas cancer |
CAPAN1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0019 |
Rb |
phosphorylation |
Ser811 |
human |
pancreas cancer |
CFPAC-1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0020 |
Rb |
phosphorylation |
Ser795 |
human |
pancreas cancer |
CAPAN1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0021 |
Rb |
phosphorylation |
Ser795 |
human |
pancreas cancer |
CFPAC-1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0022 |
Rb |
phosphorylation |
Ser780 |
human |
pancreas cancer |
CAPAN1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0023 |
Rb |
phosphorylation |
Ser780 |
human |
pancreas cancer |
CFPAC-1 |
temozolomide(TMZ) |
inhibit |
5.0 |
16170025 |
acc0024 |
histone H3 |
methylation |
Lys9 |
human |
leukemia |
AML-193 |
5-aza-2'-deoxycytidine |
modulate |
3.0 |
19881540 |
acc0025 |
histone H3 |
methylation |
Lys9 |
human |
leukemia |
Kasumi |
5-aza-2'-deoxycytidine |
modulate |
3.0 |
19881540 |
acc0026 |
histone H3 |
methylation |
Lys9 |
human |
leukemia |
KG1a |
5-aza-2'-deoxycytidine |
modulate |
3.0 |
19881540 |
acc0027 |
eIF4E histone H3 |
methylation |
Arg3 |
human |
colorectal cancer |
HCT116 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0028 |
eIF4E histone H3 |
methylation |
Arg3 |
human |
colorectal cancer |
SW620 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0029 |
FGFR3 hisone H4 |
methylation |
Arg8 |
human |
colorectal cancer |
SW620 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0030 |
FGFR3 hisone H4 |
methylation |
Arg8 |
human |
colorectal cancer |
SW480 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0031 |
eIF4E histone H3 |
methylation |
Arg3 |
human |
colorectal cancer |
SW480 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0032 |
FGFR3 hisone H4 |
methylation |
Arg3 |
human |
colorectal cancer |
HCT116 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0033 |
FGFR3 hisone H4 |
methylation |
Arg3 |
human |
colorectal cancer |
SW620 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0034 |
FGFR3 hisone H4 |
methylation |
Arg3 |
human |
colorectal cancer |
SW480 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0035 |
eIF4E histone H3 |
methylation |
Arg8 |
human |
colorectal cancer |
HCT116 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0036 |
eIF4E histone H3 |
methylation |
Arg8 |
human |
colorectal cancer |
SW620 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0037 |
eIF4E histone H3 |
methylation |
Arg8 |
human |
colorectal cancer |
SW480 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0038 |
FGFR3 hisone H4 |
methylation |
Arg8 |
human |
colorectal cancer |
HCT116 |
PRMT5 KO |
modulate |
3.0 |
26078354 |
acc0039 |
DMAP1 |
phosphorylation |
Tyr246 |
human |
pancreas cancer |
SW1990 |
paclitaxel |
resist |
5.0 |
30553276 |
acc0040 |
DMAP1 |
phosphorylation |
Tyr246 |
human |
pancreas cancer |
PANC-1 |
paclitaxel |
resist |
5.0 |
30553276 |
acc0041 |
FLT3 |
methylation |
Arg972 |
human |
leukemia |
MV4-11 |
MS023 |
modulate |
4.0 |
31217189 |
acc0042 |
FLT3 |
methylation |
Arg973 |
human |
leukemia |
MV4-11 |
MS023 |
modulate |
4.0 |
31217189 |
acc0043 |
FLT3 |
methylation |
Arg972 |
human |
leukemia |
MV4-11 |
TC-E-5003 |
modulate |
4.0 |
31217189 |
acc0044 |
FLT3 |
methylation |
Arg973 |
human |
leukemia |
MV4-11 |
TC-E-5003 |
modulate |
4.0 |
31217189 |
acc0045 |
FLT3 |
methylation |
Arg972 |
human |
leukemia |
MV4-11 |
AC220 |
decrease |
5.0 |
31217189 |
acc0046 |
FLT3 |
methylation |
Arg973 |
human |
leukemia |
MV4-11 |
AC220 |
decrease |
5.0 |
31217189 |
acc0047 |
cullin |
neddylation |
unclear |
human |
pancreas cancer |
MIA PaCa-2 |
ionizing radiation |
enhance |
4.5 |
22072567 |
acc0048 |
cullin |
neddylation |
unclear |
human |
pancreas cancer |
BxPC-3 |
ionizing radiation |
enhance |
4.5 |
22072567 |
acc0049 |
cullin |
neddylation |
unclear |
human |
pancreas cancer |
MIA PaCa-2 |
MLN4924 |
modulate |
4.0 |
22072567 |
acc0050 |
cullin |
neddylation |
unclear |
human |
pancreas cancer |
BxPC-3 |
MLN4924 |
modulate |
4.0 |
22072567 |
acc0051 |
cullin |
neddylation |
unclear |
human |
glioblastoma |
U251 |
MLN4924 |
modulate |
4.0 |
25904638 |
acc0052 |
cullin |
neddylation |
unclear |
human |
glioblastoma |
A172 |
MLN4924 |
modulate |
4.0 |
25904638 |
acc0053 |
NADPH |
oxidation |
unclear |
rat |
breast cancer |
|
tamoxifen |
decrease |
4.5 |
4004771 |
acc0054 |
NADPH |
oxidation |
unclear |
rat |
endometrial cancer |
|
tamoxifen |
decrease |
4.5 |
4004771 |
acc0055 |
VEGFR2 |
phosphorylation |
Tyr1059 |
mouse |
osteosarcoma |
MC3T3-E1 |
osteostatin |
modulate |
4.0 |
23444047 |
acc0056 |
VEGFR2 |
phosphorylation |
Tyr1059 |
mouse |
osteosarcoma |
UMR-106 |
osteostatin |
modulate |
4.0 |
23444047 |
acc0057 |
JNK |
phosphorylation |
Thr183 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0058 |
JNK |
phosphorylation |
Tyr185 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0059 |
ERK1 |
phosphorylation |
Thr202 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0060 |
ERK1 |
phosphorylation |
Tyr204 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0061 |
ERK2 |
phosphorylation |
Thr185 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0062 |
ERK2 |
phosphorylation |
Tyr187 |
Rat |
insulinoma |
RINm5F |
hypericin |
modulate |
4.0 |
26182357 |
acc0063 |
eIF2alpha |
phosphorylation |
unclear |
human |
glioblastoma |
GBM |
luteolin |
modulate |
4.0 |
30798142 |
acc0064 |
PERK |
phosphorylation |
unclear |
human |
glioblastoma |
GBM |
luteolin |
modulate |
4.0 |
30798142 |
acc0065 |
CHOP |
phosphorylation |
unclear |
human |
glioblastoma |
GBM |
luteolin |
modulate |
4.0 |
30798142 |
acc0066 |
ATF4 |
phosphorylation |
unclear |
human |
glioblastoma |
GBM |
luteolin |
modulate |
4.0 |
30798142 |
acc0067 |
SMAD2 |
phosphorylation |
unclear |
human |
glioma |
LN-308 |
ISTH1047 |
modulate |
4.0 |
31530630 |
acc0068 |
SMAD2 |
phosphorylation |
unclear |
mouse |
glioma |
SMA-560 |
ISTH1047 |
modulate |
4.0 |
31530630 |
acc0069 |
ERK1 |
phosphorylation |
Thr202 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0070 |
ERK1 |
phosphorylation |
Tyr204 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0071 |
ERK2 |
phosphorylation |
Thr185 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0072 |
ERK2 |
phosphorylation |
Tyr187 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0073 |
STAT3 |
phosphorylation |
Tyr705 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0074 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
MM |
Z-VAD-FMK/PS-341 |
modulate |
4.0 |
14627979 |
acc0075 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HuH-7-EGFRvIII |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0076 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
SMMC-7721 |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0077 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
HuH-7-EGFRvIII |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0078 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
SMMC-7721 |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0079 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HuH-7-EGFRvIII |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0080 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SMMC-7721 |
CH12 + sorafenib |
modulate |
4.0 |
22787432 |
acc0081 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
RPMI8226-R5 |
bortezomib |
inhibit |
5.0 |
25179733 |
acc0082 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
MM.1R |
bortezomib |
inhibit |
5.0 |
25179733 |
acc0083 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
MM.1R |
bortezomib |
inhibit |
5.0 |
25179733 |
acc0084 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
RPMI8226-R5 |
dexamethasone |
inhibit |
5.0 |
25179733 |
acc0085 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
MM.1R |
dexamethasone |
inhibit |
5.0 |
25179733 |
acc0086 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
RPMI8226-R5 |
doxorubicin |
inhibit |
5.0 |
25179733 |
acc0087 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
MM.1R |
doxorubicin |
inhibit |
5.0 |
25179733 |
acc0088 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
RPMI8226-R5 |
lenalidomide |
inhibit |
5.0 |
25179733 |
acc0089 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
MM.1R |
lenalidomide |
inhibit |
5.0 |
25179733 |
acc0090 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
MM.1R |
MG132 |
inhibit |
5.0 |
25179733 |
acc0091 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
RPMI8226-R5 |
dexamethasone |
inhibit |
5.0 |
25179733 |
acc0092 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
MM.1R |
dexamethasone |
inhibit |
5.0 |
25179733 |
acc0093 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
RPMI8226-R5 |
doxorubicin |
inhibit |
5.0 |
25179733 |
acc0094 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
MM.1R |
doxorubicin |
inhibit |
5.0 |
25179733 |
acc0095 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
RPMI8226-R5 |
lenalidomide |
inhibit |
5.0 |
25179733 |
acc0096 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
MM.1R |
lenalidomide |
inhibit |
5.0 |
25179733 |
acc0097 |
MARCKS |
phosphorylation |
Ser152 |
human |
myeloma |
MM.1R |
MG132 |
inhibit |
5.0 |
25179733 |
acc0098 |
MARCKS |
phosphorylation |
Ser156 |
human |
myeloma |
RPMI8226-R5 |
bortezomib |
inhibit |
5.0 |
25179733 |
acc0099 |
EGFR |
phosphorylation |
Tyr1068 |
human |
skin cancer |
Colo16 |
AEE788 |
modulate |
4.0 |
15756022 |
acc0100 |
VEGFR2 |
phosphorylation |
Tyr1054 |
human |
skin cancer |
Colo16 |
AEE788 |
modulate |
4.0 |
15756022 |
acc0101 |
AKT |
phosphorylation |
Ser473 |
human |
skin cancer |
Colo16 |
AEE788 |
modulate |
4.0 |
15756022 |
acc0102 |
MAPK |
phosphorylation |
Thr202 |
human |
skin cancer |
Colo16 |
AEE788 |
modulate |
4.0 |
15756022 |
acc0103 |
MAPK |
phosphorylation |
Tyr204 |
human |
skin cancer |
Colo16 |
AEE788 |
modulate |
4.0 |
15756022 |
acc0104 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
MGC803 |
trametinib |
reduce |
5.0 |
33035574 |
acc0105 |
EGFR |
phosphorylation |
Tyr1173 |
human |
pancreas cancer |
L3.6pl |
AEE788 |
modulate |
4.0 |
16026649 |
acc0106 |
EGFR |
phosphorylation |
Tyr1173 |
human |
pancreas cancer |
L3.6pl |
AEE788 + gemcitabine |
modulate |
4.0 |
16026649 |
acc0107 |
VEGFR |
phosphorylation |
unclear |
human |
pancreas cancer |
L3.6pl |
AEE788 |
modulate |
4.0 |
16026649 |
acc0108 |
VEGFR |
phosphorylation |
unclear |
human |
pancreas cancer |
L3.6pl |
AEE788 + gemcitabine |
modulate |
4.0 |
16026649 |
acc0109 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
L3.6pl |
AEE788 |
modulate |
4.0 |
16026649 |
acc0110 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
L3.6pl |
AEE788 + gemcitabine |
modulate |
4.0 |
16026649 |
acc0111 |
EGFR |
phosphorylation |
Tyr1173 |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 |
modulate |
4.0 |
16288027 |
acc0112 |
EGFR |
phosphorylation |
Tyr1173 |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 + gemcitabine |
modulate |
4.0 |
16288027 |
acc0113 |
VEGFR |
phosphorylation |
unclear |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 |
modulate |
4.0 |
16288027 |
acc0114 |
VEGFR |
phosphorylation |
unclear |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 + gemcitabine |
modulate |
4.0 |
16288027 |
acc0115 |
PDGFR |
phosphorylation |
Tyr716 |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 |
modulate |
4.0 |
16288027 |
acc0116 |
PDGFR |
phosphorylation |
Tyr716 |
human |
pancreas cancer |
L3.6pl |
AEE788 + STI57 + gemcitabine |
modulate |
4.0 |
16288027 |
acc0117 |
PDGFR |
phosphorylation |
Tyr716 |
human |
pancreas cancer |
L3.6pl |
STI571 |
modulate |
4.0 |
16288027 |
acc0118 |
PDGFR |
phosphorylation |
Tyr716 |
human |
pancreas cancer |
|
GN963 |
modulate |
4.0 |
16773192 |
acc0119 |
beta-catenin |
phosphorylation |
Ser41 |
human |
colorectal cancer |
SW480 |
aspirin |
modulate |
4.0 |
16878161 |
acc0120 |
beta-catenin |
phosphorylation |
Thr45 |
human |
colorectal cancer |
SW480 |
aspirin |
modulate |
4.0 |
16878161 |
acc0121 |
PP2A |
phosphorylation |
Tyr307 |
human |
colorectal cancer |
SW480 |
aspirin |
modulate |
4.0 |
16878161 |
acc0122 |
beta-catenin |
ubiquitination |
unclear |
human |
colorectal cancer |
SW480 |
aspirin |
modulate |
4.0 |
16878161 |
acc0123 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
BxPC3 |
erlotinib |
increase |
5.0 |
16928826 |
acc0124 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
BxPC3 |
erlotinib |
increase |
5.0 |
16928826 |
acc0125 |
S6 |
phosphorylation |
Ser235 |
human |
prostate cancer |
BxPC3 |
erlotinib |
increase |
5.0 |
16928826 |
acc0126 |
S6 |
phosphorylation |
Ser236 |
human |
prostate cancer |
BxPC3 |
erlotinib |
increase |
5.0 |
16928826 |
acc0127 |
Akt |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
INCB3619 |
modulate |
4.0 |
17363546 |
acc0128 |
EGFR |
phosphorylation |
Tyr1173 |
human |
breast cancer |
MDA-MB-231 |
gefitinib |
increase |
5.0 |
17363546 |
acc0129 |
EGFR |
phosphorylation |
Tyr1173 |
human |
breast cancer |
MDA-MB-231 |
erlotinib |
increase |
5.0 |
17363546 |
acc0130 |
FOXO3A |
phosphorylation |
Tyr |
human |
breast cancer |
BT474 |
lapatinib |
modulate |
4.0 |
17513611 |
acc0131 |
FOXO3A |
phosphorylation |
Tyr |
human |
breast cancer |
SK-BR-3 |
lapatinib |
modulate |
4.0 |
17513611 |
acc0132 |
FOXO3A |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-468 |
lapatinib |
modulate |
4.0 |
17513611 |
acc0133 |
FOXO3A |
phosphorylation |
Tyr |
human |
breast cancer |
T47D |
lapatinib |
modulate |
4.0 |
17513611 |
acc0134 |
EGFR |
phosphorylation |
Tyr |
human |
colorectal cancer |
HT29 |
NS-398 |
modulate |
4.0 |
17877615 |
acc0135 |
EGFR |
phosphorylation |
Tyr |
human |
colorectal cancer |
HCA7 |
NS-398 |
modulate |
4.0 |
17877615 |
acc0136 |
nNOS |
phosphorylation |
Ser847 |
rat |
pituitary tumor |
GH3 |
KN-93 |
sensitize |
5.0 |
18271754 |
acc0137 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
HL-60 |
imatinib |
no effect |
4.5 |
17187856 |
acc0138 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
HL-60 |
imatinib |
no effect |
4.5 |
17187856 |
acc0139 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
HL-60 |
imatinib |
no effect |
4.5 |
17187856 |
acc0140 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
HL-60 |
imatinib |
no effect |
4.5 |
17187856 |
acc0141 |
STAT5 |
phosphorylation |
Tyr694 |
human |
leukemia |
HL-60 |
imatinib |
no effect |
4.5 |
17187856 |
acc0142 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
HL-60 |
AD 198 |
no effect |
4.5 |
17187856 |
acc0143 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
HL-60 |
AD 198 |
no effect |
4.5 |
17187856 |
acc0144 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
HL-60 |
AD 198 |
no effect |
4.5 |
17187856 |
acc0145 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
HL-60 |
AD 198 |
no effect |
4.5 |
17187856 |
acc0146 |
STAT5 |
phosphorylation |
Tyr694 |
human |
leukemia |
HL-60 |
AD 198 |
no effect |
4.5 |
17187856 |
acc0147 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
|
GX15-070 (Obatoclax) |
reduce |
5.0 |
18596739 |
acc0148 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
|
GX15-070 (Obatoclax) + bortezomib |
reduce |
5.0 |
18596739 |
acc0149 |
AKT |
phosphorylation |
Ser473 |
human |
endometrial cancer |
Ishikawa |
Perifosine |
modulate |
4.0 |
18687514 |
acc0150 |
AKT |
phosphorylation |
Ser473 |
human |
endometrial cancer |
HEC-1A |
Perifosine |
modulate |
4.0 |
18687514 |
acc0151 |
AKT |
phosphorylation |
Ser473 |
human |
endometrial cancer |
Ishikawa |
Cisplatin |
reduce |
5.0 |
18687514 |
acc0152 |
AKT |
phosphorylation |
Thr308 |
human |
endometrial cancer |
Ishikawa |
Perifosine |
modulate |
4.0 |
18687514 |
acc0153 |
AKT |
phosphorylation |
Thr308 |
human |
endometrial cancer |
HEC-1A |
Perifosine |
modulate |
4.0 |
18687514 |
acc0154 |
AKT |
phosphorylation |
Thr308 |
human |
endometrial cancer |
Ishikawa |
Cisplatin |
reduce |
5.0 |
18687514 |
acc0155 |
Smad3 |
phosphorylation |
Ser425 |
human |
renal cancer |
FU-UR-1 |
Halofuginone |
modulate |
4.0 |
18714394 |
acc0156 |
EphA2 |
phosphorylation |
Tyr100 |
human |
pancreas cancer |
BxPC-3 |
dasatinib |
modulate |
4.0 |
18797457 |
acc0157 |
EphA2 |
phosphorylation |
Tyr100 |
human |
pancreas cancer |
PANC-1 |
dasatinib |
modulate |
4.0 |
18797457 |
acc0158 |
EphA2 |
phosphorylation |
Tyr100 |
human |
pancreas cancer |
MIA PaCa-2 |
dasatinib |
modulate |
4.0 |
18797457 |
acc0159 |
HER2 |
phosphorylation |
Tyr1221 |
human |
breast cancer |
|
tamoxifen |
resist |
5.0 |
19239686 |
acc0160 |
HER2 |
phosphorylation |
Tyr1222 |
human |
breast cancer |
|
tamoxifen |
resist |
5.0 |
19239686 |
acc0161 |
Akt |
phosphorylation |
Ser473 |
human |
schwannoma |
RT4-D6P2T |
phosphatidylinositols |
inhibit |
5.0 |
19351837 |
acc0162 |
merlin |
phosphorylation |
Ser315 |
human |
schwannoma |
RT4-D6P2T |
phosphatidylinositols |
inhibit |
5.0 |
19351837 |
acc0163 |
ATM |
phosphorylation |
Ser1981 |
human |
leukemia |
|
doxorubicin |
modulate |
4.0 |
19411853 |
acc0164 |
H2AX |
phosphorylation |
Ser139 |
human |
leukemia |
|
doxorubicin |
modulate |
3.0 |
19411853 |
acc0165 |
ATM |
phosphorylation |
Ser1981 |
human |
leukemia |
|
daunomycin |
modulate |
4.0 |
19411853 |
acc0166 |
H2AX |
phosphorylation |
Ser139 |
human |
leukemia |
|
daunomycin |
modulate |
3.0 |
19411853 |
acc0167 |
ATM |
phosphorylation |
Ser1981 |
human |
leukemia |
|
mitoxantrone |
modulate |
4.0 |
19411853 |
acc0168 |
H2AX |
phosphorylation |
Ser139 |
human |
leukemia |
|
mitoxantrone |
modulate |
3.0 |
19411853 |
acc0169 |
ATM |
phosphorylation |
Ser1981 |
human |
leukemia |
|
idarubicin |
modulate |
4.0 |
19411853 |
acc0170 |
H2AX |
phosphorylation |
Ser139 |
human |
leukemia |
|
idarubicin |
modulate |
3.0 |
19411853 |
acc0171 |
Src |
phosphorylation |
Tyr419 |
human |
sarcoma |
SaOS-2 |
dasatinib |
modulate |
4.0 |
19447875 |
acc0172 |
Src |
phosphorylation |
Tyr419 |
human |
sarcoma |
143B |
dasatinib |
modulate |
4.0 |
19447875 |
acc0173 |
VEGFR |
phosphorylation |
Tyr |
human |
leukemia |
AML |
Idarubicin |
inhibit |
5.0 |
19463770 |
acc0174 |
PDGFR |
phosphorylation |
Tyr751 |
human |
sarcoma |
MPNST |
imatinib |
modulate |
4.0 |
19627534 |
acc0175 |
STAT5 |
phosphorylation |
Tyr694 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0176 |
FLT3 |
phosphorylation |
Tyr589 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0177 |
FLT3 |
phosphorylation |
Tyr591 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0178 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0179 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0180 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0181 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0182 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
27060207 |
acc0183 |
MAPK |
phosphorylation |
unclear |
human |
ovarian cancer |
A2780 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0184 |
MAPK |
phosphorylation |
unclear |
human |
ovarian cancer |
CAOV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0185 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
SK-OV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0186 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
ES-2 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0187 |
ER |
phosphorylation |
Ser118 |
human |
ovarian cancer |
A2780 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0188 |
ER |
phosphorylation |
Ser167 |
human |
ovarian cancer |
A2780 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0189 |
ER |
phosphorylation |
Ser118 |
human |
ovarian cancer |
CAOV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0190 |
ER |
phosphorylation |
Ser167 |
human |
ovarian cancer |
CAOV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0191 |
ER |
phosphorylation |
Ser118 |
human |
ovarian cancer |
SK-OV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0192 |
ER |
phosphorylation |
Ser167 |
human |
ovarian cancer |
SK-OV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0193 |
ER |
phosphorylation |
Ser118 |
human |
ovarian cancer |
ES-2 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0194 |
ER |
phosphorylation |
Ser167 |
human |
ovarian cancer |
ES-2 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0195 |
MAPK |
phosphorylation |
unclear |
human |
ovarian cancer |
SK-OV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0196 |
MAPK |
phosphorylation |
unclear |
human |
ovarian cancer |
ES-2 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0197 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
A2780 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0198 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
CAOV-3 |
tamoxifen |
modulate |
4.0 |
20056081 |
acc0199 |
IkB |
phosphorylation |
unclear |
human |
prostate cancer |
DU145 |
EC-70124 |
modulate |
4.0 |
26826115 |
acc0200 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
EC-70124 |
modulate |
4.0 |
26826115 |
acc0201 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
prostate cancer |
DU145 |
EC-70124 |
modulate |
4.0 |
26826115 |
acc0202 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
prostate cancer |
DU145 |
EC-70124 |
modulate |
4.0 |
26826115 |
acc0203 |
FAK |
phosphorylation |
Tyr397 |
mouse |
breast cancer |
4T1 |
PND-1186 |
modulate |
4.0 |
20234191 |
acc0204 |
FAK |
phosphorylation |
Tyr397 |
mouse |
ovarian cancer |
ID8 |
PND-1186 |
modulate |
4.0 |
20234191 |
acc0205 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
SK-OV-3 |
JMR-132 |
modulate |
4.0 |
20509930 |
acc0206 |
AKT |
phosphorylation |
unclear |
human |
ovarian cancer |
CaOV3 |
JMR-132 |
modulate |
4.0 |
20509930 |
acc0207 |
IkappaBalpha |
phosphorylation |
unclear |
human |
pancreas cancer |
PANC-1 |
nafamostat mesilate |
modulate |
4.0 |
20811662 |
acc0208 |
IRF-3 |
phosphorylation |
Ser396 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0209 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0210 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0211 |
STAT1 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0212 |
JAK1 |
phosphorylation |
Tyr701 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0213 |
Tyk2 |
phosphorylation |
Tyr1054 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0214 |
Tyk2 |
phosphorylation |
Tyr1055 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0215 |
STAT2 |
phosphorylation |
Tyr690 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0216 |
STAT5 |
phosphorylation |
Tyr694 |
human |
medulloblastoma |
TE671 |
ISG15 OV |
modulate |
3.0 |
20035788 |
acc0217 |
GSK3beta |
phosphorylation |
Ser9 |
human |
ovarian cancer |
OVCAR-3 |
GnRH-II |
modulate |
4.0 |
21239435 |
acc0218 |
GSK3beta |
phosphorylation |
Ser9 |
human |
ovarian cancer |
CaOV-3 |
GnRH-II |
modulate |
4.0 |
21239435 |
acc0219 |
MYC |
phosphorylation |
Ser62 |
human |
hepatocellular carcinoma |
HuH-7 |
atorvastatin (AT) |
modulate |
4.0 |
21262914 |
acc0220 |
MYC |
phosphorylation |
Ser62 |
human |
hepatocellular carcinoma |
HepG2 |
atorvastatin (AT) |
modulate |
4.0 |
21262914 |
acc0221 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
hepatocellular carcinoma |
SNU-449 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0222 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
hepatocellular carcinoma |
HuH-7 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0223 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-367 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0224 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HepG2 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0225 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
hepatocellular carcinoma |
SNU-367 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0226 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
hepatocellular carcinoma |
HepG2 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0227 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
hepatocellular carcinoma |
SNU-449 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0228 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
hepatocellular carcinoma |
HuH-7 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0229 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
hepatocellular carcinoma |
SNU-367 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0230 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
hepatocellular carcinoma |
HepG2 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0231 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-449 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0232 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HuH-7 |
Celecoxib |
modulate |
4.0 |
21490132 |
acc0233 |
JNK |
phosphorylation |
Thr181 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0234 |
JNK |
phosphorylation |
Thr181 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0235 |
ERK1 |
phosphorylation |
Thr202 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0236 |
ERK1 |
phosphorylation |
Tyr204 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0237 |
ERK2 |
phosphorylation |
Thr185 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0238 |
ERK2 |
phosphorylation |
Tyr187 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0239 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0240 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0241 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0242 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0243 |
JNK |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0244 |
JNK |
phosphorylation |
Thr185 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0245 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0246 |
STAT3 |
phosphorylation |
Tyr705 |
human |
renal cancer |
A489 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0247 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0248 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0249 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0250 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MCF7 |
NSC-743380 |
modulate |
4.0 |
22174819 |
acc0251 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780 |
arsenic trioxide (ATO) |
modulate |
4.0 |
21655183 |
acc0252 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
COC1 |
arsenic trioxide (ATO) |
modulate |
4.0 |
21655183 |
acc0253 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
COC1/CP |
arsenic trioxide (ATO) |
modulate |
4.0 |
21655183 |
acc0254 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780/CP |
arsenic trioxide (ATO) |
modulate |
4.0 |
21655183 |
acc0255 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
OVCAR-3 |
arsenic trioxide (ATO) |
modulate |
4.0 |
21655183 |
acc0256 |
p65 |
phosphorylation |
Ser536 |
Hamster |
oral cancer |
|
Andrographolide |
modulate |
4.0 |
21841043 |
acc0257 |
IkappaBalpha |
phosphorylation |
Ser32 |
Hamster |
oral cancer |
|
Andrographolide |
modulate |
4.0 |
21841043 |
acc0258 |
IkappaBalpha |
phosphorylation |
Ser36 |
Hamster |
oral cancer |
|
Andrographolide |
modulate |
4.0 |
21841043 |
acc0259 |
VEGFR2 |
phosphorylation |
Tyr1175 |
human |
hepatocellular carcinoma |
KYN-2 |
vandetanib |
modulate |
4.0 |
22611027 |
acc0260 |
VEGFR2 |
phosphorylation |
Tyr1175 |
human |
hepatocellular carcinoma |
HAK1-B |
vandetanib |
modulate |
4.0 |
22611027 |
acc0261 |
VEGFR2 |
phosphorylation |
Tyr1175 |
human |
hepatocellular carcinoma |
HuH-7 |
vandetanib |
modulate |
4.0 |
22611027 |
acc0262 |
EGFR |
phosphorylation |
Tyr1173 |
human |
hepatocellular carcinoma |
KYN-2 |
vandetanib |
modulate |
4.0 |
22611027 |
acc0263 |
EGFR |
phosphorylation |
Tyr1173 |
human |
hepatocellular carcinoma |
HAK1-B |
vandetanib |
modulate |
4.0 |
22611027 |
acc0264 |
EGFR |
phosphorylation |
Tyr1173 |
human |
hepatocellular carcinoma |
HuH-7 |
vandetanib |
modulate |
4.0 |
22611027 |
acc0265 |
MET |
phosphorylation |
Tyr1234 |
human |
ovarian cancer |
58As9 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0266 |
MET |
phosphorylation |
Tyr1234 |
human |
gastric cancer |
SNU5 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0267 |
MET |
phosphorylation |
Tyr1234 |
human |
hepatocellular carcinoma |
HSC58 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0268 |
MET |
phosphorylation |
Tyr1234 |
human |
ovarian cancer |
58As1 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0269 |
MET |
phosphorylation |
Tyr1235 |
human |
ovarian cancer |
58As9 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0270 |
MET |
phosphorylation |
Tyr1235 |
human |
gastric cancer |
SNU5 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0271 |
MET |
phosphorylation |
Tyr1235 |
human |
hepatocellular carcinoma |
HSC58 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0272 |
MET |
phosphorylation |
Tyr1235 |
human |
ovarian cancer |
58As1 |
crizotinib |
modulate |
4.0 |
22729845 |
acc0273 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT29 |
PMA |
modulate |
4.0 |
22812190 |
acc0274 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT29 |
PMA |
modulate |
4.0 |
22812190 |
acc0275 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT29 |
PMA |
modulate |
4.0 |
22812190 |
acc0276 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT29 |
PMA |
modulate |
4.0 |
22812190 |
acc0277 |
ITGB4 |
phosphorylation |
Ser1356 |
human |
skin cancer |
A431 |
cyclosporin A (CsA) |
modulate |
4.0 |
22865863 |
acc0278 |
ITGB4 |
phosphorylation |
Ser1356 |
human |
tongue cancer |
SCC25 |
cyclosporin A (CsA) |
modulate |
4.0 |
22865863 |
acc0279 |
ITGB4 |
phosphorylation |
Ser1356 |
human |
skin cancer |
Colo16 |
cyclosporin A (CsA) |
modulate |
4.0 |
22865863 |
acc0280 |
SRC |
phosphorylation |
Tyr416 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0281 |
SRC |
phosphorylation |
Tyr416 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0282 |
FAK |
phosphorylation |
Tyr576 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0283 |
FAK |
phosphorylation |
Tyr576 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0284 |
FAK |
phosphorylation |
Tyr577 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0285 |
FAK |
phosphorylation |
Tyr577 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0286 |
FAK |
phosphorylation |
Tyr577 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0287 |
FAK |
phosphorylation |
Tyr577 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0288 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0289 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0290 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0291 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0292 |
SRC |
phosphorylation |
Tyr416 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0293 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0294 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0295 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0296 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0297 |
SRC |
phosphorylation |
Tyr416 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0298 |
AKT |
phosphorylation |
Ser473 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0299 |
AKT |
phosphorylation |
Ser473 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0300 |
AKT |
phosphorylation |
Ser473 |
human |
sarcoma |
FUJI |
dasatinib |
modulate |
4.0 |
23580575 |
acc0301 |
AKT |
phosphorylation |
Ser473 |
human |
sarcoma |
SYO-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0302 |
FAK |
phosphorylation |
Tyr576 |
human |
sarcoma |
CME-1 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0303 |
FAK |
phosphorylation |
Tyr576 |
human |
sarcoma |
1273/99 |
dasatinib |
modulate |
4.0 |
23580575 |
acc0304 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
A2780/CP |
beta-Elemene + cisplatin |
modulate |
4.0 |
23277286 |
acc0305 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
MCAS |
beta-Elemene + cisplatin |
modulate |
4.0 |
23277286 |
acc0306 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23319394 |
acc0307 |
p70S6K |
phosphorylation |
Thr389 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23319394 |
acc0308 |
S6RP |
phosphorylation |
Ser235 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23319394 |
acc0309 |
S6RP |
phosphorylation |
Ser236 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23319394 |
acc0310 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
PC9 |
BEZ235 |
modulate |
4.0 |
23319394 |
acc0311 |
p70S6K |
phosphorylation |
Thr389 |
human |
lung cancer |
PC9 |
BEZ235 |
modulate |
4.0 |
23319394 |
acc0312 |
S6RP |
phosphorylation |
Ser235 |
human |
lung cancer |
PC9 |
BEZ235 |
modulate |
4.0 |
23319394 |
acc0313 |
S6RP |
phosphorylation |
Ser236 |
human |
lung cancer |
PC9 |
BEZ235 |
modulate |
4.0 |
23319394 |
acc0314 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
BxPC3 |
rapamycin |
modulate |
4.0 |
23443316 |
acc0315 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
rapamycin |
modulate |
4.0 |
23443316 |
acc0316 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT29 |
3-deazaneplanocin A (DZNep) |
modulate |
4.0 |
23588203 |
acc0317 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
|
3-deazaneplanocin A (DZNep) |
modulate |
4.0 |
23588203 |
acc0318 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
ovarian cancer |
OVCAR-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0319 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
ovarian cancer |
SK-OV-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0320 |
IkappaBalpha |
phosphorylation |
Ser36 |
human |
ovarian cancer |
OVCAR-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0321 |
IkappaBalpha |
phosphorylation |
Ser36 |
human |
ovarian cancer |
SK-OV-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0322 |
p65 |
phosphorylation |
Ser536 |
human |
ovarian cancer |
OVCAR-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0323 |
p65 |
phosphorylation |
Ser536 |
human |
ovarian cancer |
SK-OV-3 |
Minocycline |
modulate |
4.0 |
23858099 |
acc0324 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
CSQT-2 |
all-trans retinoic acid (ATRA) + cisplatin |
modulate |
4.0 |
23867314 |
acc0325 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
HuH-7 |
all-trans retinoic acid (ATRA) + cisplatin |
modulate |
4.0 |
23867314 |
acc0326 |
AKT |
phosphorylation |
Ser473 |
human |
hemangioma |
|
rapamycin |
modulate |
4.0 |
23938603 |
acc0327 |
PKCalpha |
phosphorylation |
Ser657 |
human |
hemangioma |
|
rapamycin |
modulate |
4.0 |
23938603 |
acc0328 |
EGFR |
phosphorylation |
Tyr1173 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0329 |
EGFR |
phosphorylation |
Tyr1173 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0330 |
ERK2 |
phosphorylation |
Thr185 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0331 |
ERK2 |
phosphorylation |
Tyr187 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0332 |
AKT |
phosphorylation |
Thr308 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0333 |
AKT |
phosphorylation |
Thr308 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0334 |
ERK1 |
phosphorylation |
Thr202 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0335 |
ERK1 |
phosphorylation |
Tyr204 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0336 |
ERK2 |
phosphorylation |
Thr185 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0337 |
ERK2 |
phosphorylation |
Tyr187 |
human |
thyroid cancer |
8305C |
sunitinib |
modulate |
4.0 |
23969186 |
acc0338 |
ERK1 |
phosphorylation |
Thr202 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0339 |
ERK1 |
phosphorylation |
Tyr204 |
human |
thyroid cancer |
FB3 |
sunitinib |
modulate |
4.0 |
23969186 |
acc0340 |
GSK3b |
phosphorylation |
Ser9 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib |
enhance |
5.0 |
24113128 |
acc0341 |
GSK3b |
phosphorylation |
Ser9 |
human |
hepatocellular carcinoma |
HuH-7 |
sorafenib |
enhance |
5.0 |
24113128 |
acc0342 |
S6K |
phosphorylation |
Thr389 |
human |
colorectal cancer |
HT29 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0343 |
S6K |
phosphorylation |
Thr389 |
human |
colorectal cancer |
DLD-1 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0344 |
S6 |
phosphorylation |
Ser235 |
human |
colorectal cancer |
HT29 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0345 |
S6 |
phosphorylation |
Ser235 |
human |
colorectal cancer |
DLD-1 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0346 |
S6 |
phosphorylation |
Ser236 |
human |
colorectal cancer |
HT29 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0347 |
S6 |
phosphorylation |
Ser236 |
human |
colorectal cancer |
DLD-1 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0348 |
Akt |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT29 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0349 |
Akt |
phosphorylation |
Ser473 |
human |
colorectal cancer |
DLD-1 |
AZD2014 |
modulate |
4.0 |
24309100 |
acc0350 |
p27 |
phosphorylation |
Thr187 |
human |
hepatocellular carcinoma |
HuH-7 |
MIF4GD OV |
modulate |
3.0 |
24336329 |
acc0351 |
AKT |
phosphorylation |
Ser473 |
human |
renal cancer |
786-O |
NVP-BEZ235 |
inhibit |
5.0 |
24448243 |
acc0352 |
AKT |
phosphorylation |
Ser473 |
human |
renal cancer |
UOK101 |
NVP-BEZ235 |
inhibit |
5.0 |
24448243 |
acc0353 |
AKT |
phosphorylation |
Ser473 |
human |
renal cancer |
RCC4 |
NVP-BEZ235 |
inhibit |
5.0 |
24448243 |
acc0354 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
PC3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0355 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MCF7 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0356 |
p70S6K |
phosphorylation |
Thr389 |
human |
prostate cancer |
PC3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0357 |
p70S6K |
phosphorylation |
Thr389 |
human |
breast cancer |
MCF7 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0358 |
p70S6K |
phosphorylation |
Thr389 |
human |
lung cancer |
A549 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0359 |
p70S6K |
phosphorylation |
Thr389 |
human |
ovarian cancer |
OVCAR-3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0360 |
p70S6K |
phosphorylation |
Thr389 |
human |
glioblastoma |
U87-MG |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0361 |
S6 |
phosphorylation |
Ser240 |
human |
prostate cancer |
PC3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0362 |
S6 |
phosphorylation |
Ser240 |
human |
breast cancer |
MCF7 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0363 |
S6 |
phosphorylation |
Ser240 |
human |
lung cancer |
A549 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0364 |
S6 |
phosphorylation |
Ser240 |
human |
ovarian cancer |
OVCAR-3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0365 |
S6 |
phosphorylation |
Ser240 |
human |
glioblastoma |
U87-MG |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0366 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
A549 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0367 |
S6 |
phosphorylation |
Ser244 |
human |
prostate cancer |
PC3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0368 |
S6 |
phosphorylation |
Ser244 |
human |
breast cancer |
MCF7 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0369 |
S6 |
phosphorylation |
Ser244 |
human |
lung cancer |
A549 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0370 |
S6 |
phosphorylation |
Ser244 |
human |
ovarian cancer |
OVCAR-3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0371 |
S6 |
phosphorylation |
Ser244 |
human |
glioblastoma |
U87-MG |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0372 |
AKT |
phosphorylation |
Thr308 |
human |
ovarian cancer |
OVCAR-3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0373 |
AKT |
phosphorylation |
Thr308 |
human |
glioblastoma |
U87-MG |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0374 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0375 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0376 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0377 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
OVCAR-3 |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0378 |
AKT |
phosphorylation |
Ser473 |
human |
glioblastoma |
U87-MG |
XL765 (SAR245409) |
modulate |
4.0 |
24634413 |
acc0379 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
BxPc-3 |
alpha -Mangostin |
modulate |
4.0 |
24812621 |
acc0380 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
alpha -Mangostin |
modulate |
4.0 |
24812621 |
acc0381 |
STAT1 |
phosphorylation |
Tyr701 |
human |
meningioma |
IOMM-Lee |
LB-100 |
modulate |
4.0 |
36203966 |
acc0382 |
mTOR |
phosphorylation |
Ser2448 |
human |
hepatocellular carcinoma |
HuH-7 |
radiotherapy |
inhibit |
4.5 |
25004403 |
acc0383 |
mTOR |
phosphorylation |
Ser2448 |
mouse |
hepatocellular carcinoma |
BNL |
radiotherapy |
inhibit |
4.5 |
25004403 |
acc0384 |
Akt |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
HuH-7 |
radiotherapy |
inhibit |
4.5 |
25004403 |
acc0385 |
Akt |
phosphorylation |
Ser473 |
mouse |
hepatocellular carcinoma |
BNL |
radiotherapy |
inhibit |
4.5 |
25004403 |
acc0386 |
VASP |
phosphorylation |
Ser239 |
mouse |
colorectal cancer |
CT26 |
Baicalein |
modulate |
4.0 |
25268843 |
acc0387 |
VASP |
phosphorylation |
Ser157 |
mouse |
colorectal cancer |
CT26 |
Baicalein |
modulate |
4.0 |
25268843 |
acc0388 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
bevacizumab |
resist |
5.0 |
25319392 |
acc0389 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
GOC2 |
bevacizumab |
resist |
5.0 |
25319392 |
acc0390 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
GOC-A2 |
bevacizumab |
resist |
5.0 |
25319392 |
acc0391 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
OVCAR-3 |
bevacizumab |
resist |
5.0 |
25319392 |
acc0392 |
HSP27 |
phosphorylation |
Ser78 |
human |
colorectal cancer |
HCT116 |
5-fluorouracil |
inhibit |
5.0 |
25364415 |
acc0393 |
HSP27 |
phosphorylation |
Ser78 |
human |
colorectal cancer |
HCT15 |
5-fluorouracil |
inhibit |
5.0 |
25364415 |
acc0394 |
HSP27 |
phosphorylation |
Ser78 |
human |
colorectal cancer |
HT29 |
5-fluorouracil |
inhibit |
5.0 |
25364415 |
acc0395 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
TOV112D |
bortezomib |
modulate |
4.0 |
25375375 |
acc0396 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
TOV21G |
bortezomib |
modulate |
4.0 |
25375375 |
acc0397 |
ERK1 |
phosphorylation |
Thr202 |
human |
endometrial cancer |
Ishikawa |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0398 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
HepG2 |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0399 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
TOV112D |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0400 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
TOV21G |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0401 |
ERK1 |
phosphorylation |
Tyr204 |
human |
endometrial cancer |
Ishikawa |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0402 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HepG2 |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0403 |
ERK1 |
phosphorylation |
Thr202 |
human |
endometrial cancer |
Ishikawa |
bortezomib |
modulate |
4.0 |
25375375 |
acc0404 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
HepG2 |
bortezomib |
modulate |
4.0 |
25375375 |
acc0405 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
TOV112D |
bortezomib |
modulate |
4.0 |
25375375 |
acc0406 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
TOV21G |
bortezomib |
modulate |
4.0 |
25375375 |
acc0407 |
ERK1 |
phosphorylation |
Tyr204 |
human |
endometrial cancer |
Ishikawa |
bortezomib |
modulate |
4.0 |
25375375 |
acc0408 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HepG2 |
bortezomib |
modulate |
4.0 |
25375375 |
acc0409 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
TOV112D |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0410 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
TOV21G |
Cisplatin |
enhance |
5.0 |
25375375 |
acc0411 |
Src |
phosphorylation |
Tyr416 |
human |
gastric cancer |
SGC7901 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0412 |
Src |
phosphorylation |
Tyr416 |
human |
gastric cancer |
MGC803 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0413 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
gastric cancer |
SGC7901 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0414 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
gastric cancer |
MGC803 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0415 |
Akt |
phosphorylation |
Ser473 |
human |
gastric cancer |
SGC7901 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0416 |
Akt |
phosphorylation |
Ser473 |
human |
gastric cancer |
MGC803 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0417 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
gastric cancer |
SGC7901 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0418 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
gastric cancer |
MGC803 |
cetuximab |
inhibit |
5.0 |
25625229 |
acc0419 |
STAT1 |
phosphorylation |
Tyr701 |
human |
pancreas cancer |
SW1990 |
gemcitabine |
increase |
5.0 |
30782607 |
acc0420 |
STAT1 |
phosphorylation |
Tyr701 |
human |
prostate cancer |
BxPC3 |
gemcitabine |
increase |
5.0 |
30782607 |
acc0421 |
MEK |
phosphorylation |
Ser217 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0422 |
MEK |
phosphorylation |
Ser217 |
human |
ovarian cancer |
OVCAR8 |
navitoclax |
increase |
5.0 |
25968887 |
acc0423 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0424 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0425 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0426 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0427 |
MEK |
phosphorylation |
Ser221 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0428 |
MEK |
phosphorylation |
Ser221 |
human |
ovarian cancer |
OVCAR8 |
navitoclax |
increase |
5.0 |
25968887 |
acc0429 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0430 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0431 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0432 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
MCAS |
navitoclax |
increase |
5.0 |
25968887 |
acc0433 |
MEK |
phosphorylation |
Ser217 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0434 |
MEK |
phosphorylation |
Ser221 |
human |
ovarian cancer |
MCAS |
trametinib |
increase |
5.0 |
25968887 |
acc0435 |
CSE1L |
phosphorylation |
unclear |
human |
colorectal cancer |
HT29 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0436 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT29 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0437 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT29 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0438 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT29 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0439 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT29 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0440 |
CSE1L |
phosphorylation |
unclear |
human |
melanoma |
A375 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0441 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
A375 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0442 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
A375 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0443 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
A375 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0444 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
A375 |
vemurafenib + sorafenib |
modulate |
4.0 |
26070816 |
acc0445 |
AMPK |
phosphorylation |
Thr180 |
human |
colorectal cancer |
HT29 |
TPA |
modulate |
4.0 |
26116564 |
acc0446 |
AMPK |
phosphorylation |
Thr180 |
human |
colorectal cancer |
SW620 |
TPA |
modulate |
4.0 |
26116564 |
acc0447 |
AMPK |
phosphorylation |
Tyr182 |
human |
colorectal cancer |
HT29 |
TPA |
modulate |
4.0 |
26116564 |
acc0448 |
AMPK |
phosphorylation |
Tyr182 |
human |
colorectal cancer |
SW620 |
TPA |
modulate |
4.0 |
26116564 |
acc0449 |
Smad3 |
phosphorylation |
Ser423 |
human |
hepatocellular carcinoma |
HCC |
sorafenib |
increase |
5.0 |
26666823 |
acc0450 |
Smad3 |
phosphorylation |
Ser425 |
human |
hepatocellular carcinoma |
HCC |
sorafenib |
increase |
5.0 |
26666823 |
acc0451 |
AKT |
phosphorylation |
Ser473 |
human |
esophageal cancer |
EC9706 |
rapamycin |
inhibit |
5.0 |
26725440 |
acc0452 |
PI3K |
phosphorylation |
Tyr199 |
human |
gastric cancer |
YCC1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0453 |
PI3K |
phosphorylation |
Tyr199 |
human |
gastric cancer |
SNU1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0454 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
SNU1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0455 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
Hs746T |
mefloquine |
modulate |
4.0 |
26780727 |
acc0456 |
mTOR |
phosphorylation |
Ser2481 |
human |
gastric cancer |
YCC1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0457 |
mTOR |
phosphorylation |
Ser2481 |
human |
gastric cancer |
SNU1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0458 |
mTOR |
phosphorylation |
Ser2481 |
human |
gastric cancer |
Hs746T |
mefloquine |
modulate |
4.0 |
26780727 |
acc0459 |
PI3K |
phosphorylation |
Tyr199 |
human |
gastric cancer |
Hs746T |
mefloquine |
modulate |
4.0 |
26780727 |
acc0460 |
rS6 |
phosphorylation |
Ser235 |
human |
gastric cancer |
YCC1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0461 |
rS6 |
phosphorylation |
Ser235 |
human |
gastric cancer |
SNU1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0462 |
rS6 |
phosphorylation |
Ser235 |
human |
gastric cancer |
Hs746T |
mefloquine |
modulate |
4.0 |
26780727 |
acc0463 |
rS6 |
phosphorylation |
Ser236 |
human |
gastric cancer |
YCC1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0464 |
rS6 |
phosphorylation |
Ser236 |
human |
gastric cancer |
SNU1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0465 |
rS6 |
phosphorylation |
Ser236 |
human |
gastric cancer |
Hs746T |
mefloquine |
modulate |
4.0 |
26780727 |
acc0466 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
YCC1 |
mefloquine |
modulate |
4.0 |
26780727 |
acc0467 |
STAT1 |
phosphorylation |
Tyr701 |
human |
leukemia |
|
fludarabine |
enhance |
5.0 |
18182577 |
acc0468 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
|
fludarabine |
enhance |
5.0 |
18182577 |
acc0469 |
STAT1 |
phosphorylation |
Tyr701 |
human |
leukemia |
|
rituximab |
enhance |
5.0 |
18182577 |
acc0470 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
|
rituximab |
enhance |
5.0 |
18182577 |
acc0471 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
AGS |
Cisplatin |
inhibit |
5.0 |
26998277 |
acc0472 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
AGS |
Cisplatin |
inhibit |
5.0 |
26998277 |
acc0473 |
YB1 |
phosphorylation |
Ser102 |
human |
gastric cancer |
MGC803 |
Cisplatin |
inhibit |
5.0 |
27013200 |
acc0474 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
A549 |
RAD001 |
inhibit |
5.0 |
27050281 |
acc0475 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H157 |
RAD001 |
inhibit |
5.0 |
27050281 |
acc0476 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H157 |
CGP57380 + RAD001 |
modulate |
4.0 |
27050281 |
acc0477 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
CGP57380 + RAD001 |
modulate |
4.0 |
27050281 |
acc0478 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
A549 |
CGP57380 + RAD001 |
modulate |
4.0 |
27050281 |
acc0479 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
CGP57380 + RAD001 |
modulate |
4.0 |
27050281 |
acc0480 |
CCND1 |
phosphorylation |
Thr286 |
human |
colorectal cancer |
HCT116 |
kahweol |
modulate |
4.0 |
27424123 |
acc0481 |
CCND1 |
phosphorylation |
Thr286 |
human |
colorectal cancer |
SW480 |
kahweol |
modulate |
4.0 |
27424123 |
acc0482 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
SGC7901 |
MK-2206 + 5-fluorouracil |
modulate |
4.0 |
27499633 |
acc0483 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
SGC7901 |
MK-2206 + doxorubicin |
modulate |
4.0 |
27499633 |
acc0484 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
MKN45 |
MK-2206 + 5-fluorouracil |
modulate |
4.0 |
27499633 |
acc0485 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
MKN45 |
MK-2206 + doxorubicin |
modulate |
4.0 |
27499633 |
acc0486 |
STAT1 |
phosphorylation |
Ser727 |
human |
leukemia |
SET-2 |
cortistatin A |
modulate |
4.0 |
29239838 |
acc0487 |
STAT1 |
phosphorylation |
Ser727 |
human |
leukemia |
UKE-1 |
cortistatin A |
modulate |
4.0 |
29239838 |
acc0488 |
FAK |
phosphorylation |
Tyr397 |
human |
hepatocellular carcinoma |
HepG2 |
cabozantinib |
inhibit |
5.0 |
27638856 |
acc0489 |
FAK |
phosphorylation |
Tyr397 |
human |
hepatocellular carcinoma |
Bel-7402 |
cabozantinib |
inhibit |
5.0 |
27638856 |
acc0490 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
HepG2 |
cabozantinib + CT-707 |
modulate |
4.0 |
27638856 |
acc0491 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
Bel-7402 |
cabozantinib + CT-707 |
modulate |
4.0 |
27638856 |
acc0492 |
eIF4E |
phosphorylation |
Ser209 |
human |
hepatocellular carcinoma |
HepG2 |
cercosporamide |
modulate |
4.0 |
27662474 |
acc0493 |
eIF4E |
phosphorylation |
Ser209 |
human |
hepatocellular carcinoma |
HCC-EC |
cercosporamide |
modulate |
4.0 |
27662474 |
acc0494 |
eIF4E |
phosphorylation |
Ser209 |
human |
hepatocellular carcinoma |
HepG2 |
Cisplatin |
inhibit |
5.0 |
27662474 |
acc0495 |
eIF4E |
phosphorylation |
Ser209 |
human |
hepatocellular carcinoma |
HCC-EC |
Cisplatin |
inhibit |
5.0 |
27662474 |
acc0496 |
PPARgamma |
phosphorylation |
Ser84 |
human |
hepatocellular carcinoma |
HepG2 |
PD0325901 |
modulate |
4.0 |
27769068 |
acc0497 |
PPARgamma |
phosphorylation |
Ser82 |
mouse |
hepatocellular carcinoma |
Hepa1-6 |
PD0325901 |
modulate |
4.0 |
27769068 |
acc0498 |
ATR |
phosphorylation |
Ser428 |
human |
head and neck cancer |
SCC61 |
Cisplatin |
modulate |
4.0 |
27863405 |
acc0499 |
ATR |
phosphorylation |
Ser428 |
human |
head and neck cancer |
SCC25 |
Cisplatin |
modulate |
4.0 |
27863405 |
acc0500 |
ATR |
phosphorylation |
Ser428 |
human |
ovarian cancer |
OVCAR-8 |
Cisplatin |
modulate |
4.0 |
27863405 |
acc0501 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
KLM1-R |
LY294002 |
modulate |
4.0 |
28000865 |
acc0502 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PK59 |
LY294002 |
modulate |
4.0 |
28000865 |
acc0503 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
KLM1-R |
gemcitabine |
inhibit |
5.0 |
28000865 |
acc0504 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PK59 |
gemcitabine |
inhibit |
5.0 |
28000865 |
acc0505 |
STAT1 |
phosphorylation |
Ser727 |
human |
ovarian cancer |
TOV112D |
bortezomib |
inhibit |
5.0 |
23449448 |
acc0506 |
STAT1 |
phosphorylation |
Tyr701 |
human |
ovarian cancer |
TOV112D |
bortezomib |
inhibit |
5.0 |
23449448 |
acc0507 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
Cisplatin |
resist |
5.0 |
28685895 |
acc0508 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780 |
Cisplatin |
resist |
5.0 |
28685895 |
acc0509 |
VEGFR2 |
phosphorylation |
Tyr1175 |
human |
bladder cancer |
T24 |
AE-AS |
modulate |
4.0 |
28710377 |
acc0510 |
Chk1 |
phosphorylation |
Ser345 |
human |
pancreas cancer |
MIA PaCa-2 |
gemcitabine |
inhibit |
5.0 |
29048622 |
acc0511 |
Smad2 |
phosphorylation |
Ser465 |
human |
breast cancer |
MDA-MB-231 |
Nafamostat mesilate(NM) |
modulate |
4.0 |
29196918 |
acc0512 |
Smad2 |
phosphorylation |
Ser467 |
human |
breast cancer |
MDA-MB-231 |
Nafamostat mesilate(NM) |
modulate |
4.0 |
29196918 |
acc0513 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MDA-MB-231 |
NM |
modulate |
4.0 |
29196918 |
acc0514 |
DNMT1 |
ubiquitination |
unclear |
human |
colorectal cancer |
HCT-8-7T |
alisertib |
modulate |
4.0 |
34522170 |
acc0515 |
DNMT1 |
ubiquitination |
unclear |
human |
colorectal cancer |
HCT-8-9T |
alisertib |
modulate |
4.0 |
34522170 |
acc0516 |
STAT1 |
ubiquitination |
Tyr701 |
human |
colorectal cancer |
HCT-8-7T |
alisertib |
inhibit |
5.0 |
34522170 |
acc0517 |
STAT1 |
ubiquitination |
Tyr701 |
human |
colorectal cancer |
HCT-8-9T |
alisertib |
inhibit |
5.0 |
34522170 |
acc0518 |
beta-catenin |
phosphorylation |
Ser45 |
human |
thyroid cancer |
SW1736 |
I131 |
inhibit |
4.5 |
29344218 |
acc0519 |
beta-catenin |
phosphorylation |
Tyr654 |
human |
thyroid cancer |
SW1736 |
I131 |
inhibit |
4.5 |
29344218 |
acc0520 |
GSK-3beta |
phosphorylation |
Ser9 |
human |
thyroid cancer |
SW1736 |
I131 |
inhibit |
4.5 |
29344218 |
acc0521 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
|
trametinib |
modulate |
4.0 |
29419436 |
acc0522 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
|
trametinib |
modulate |
4.0 |
29419436 |
acc0523 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
|
trametinib |
modulate |
4.0 |
29419436 |
acc0524 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
|
trametinib |
modulate |
4.0 |
29419436 |
acc0525 |
GFAT1 |
phosphorylation |
Ser243 |
human |
pancreas cancer |
MIA PaCa-2 |
2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0526 |
AMPK |
phosphorylation |
Thr172 |
human |
pancreas cancer |
MIA PaCa-2 |
2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0527 |
AMPK |
phosphorylation |
Thr183 |
human |
pancreas cancer |
MIA PaCa-2 |
2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0528 |
GFAT1 |
phosphorylation |
Ser243 |
human |
pancreas cancer |
MIA PaCa-2 |
Met + 2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0529 |
AMPK |
phosphorylation |
Thr172 |
human |
pancreas cancer |
MIA PaCa-2 |
Met + 2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0530 |
AMPK |
phosphorylation |
Thr183 |
human |
pancreas cancer |
MIA PaCa-2 |
Met + 2-Deoxy-d-glucose |
modulate |
4.0 |
29753740 |
acc0531 |
ERK1 |
phosphorylation |
Thr202 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0532 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0533 |
ERK2 |
phosphorylation |
Thr185 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0534 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0535 |
SMAD2 |
phosphorylation |
Ser465 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0536 |
SMAD2 |
phosphorylation |
Ser467 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0537 |
SMAD3 |
phosphorylation |
Ser423 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0538 |
SMAD3 |
phosphorylation |
Ser425 |
rat |
pituitary tumor |
GH3 |
trastuzumab + TGFB1 |
modulate |
4.0 |
29875136 |
acc0539 |
Smad2 |
phosphorylation |
Thr8 |
human |
pancreas cancer |
BxPC-3 |
metformin |
modulate |
4.0 |
29956804 |
acc0540 |
Smad2 |
phosphorylation |
Thr8 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
29956804 |
acc0541 |
Smad3 |
phosphorylation |
Thr8 |
human |
pancreas cancer |
BxPC-3 |
metformin |
modulate |
4.0 |
29956804 |
acc0542 |
Smad3 |
phosphorylation |
Thr8 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
29956804 |
acc0543 |
HK-2 |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
HepG2 |
limonin |
modulate |
4.0 |
30013360 |
acc0544 |
STAT1 |
phosphorylation |
Ser727 |
human |
pancreas cancer |
L3.6pl |
EGFRBi armed ATC |
modulate |
4.0 |
23185240 |
acc0545 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
L3.6pl |
EGFRBi armed ATC |
modulate |
4.0 |
23185240 |
acc0546 |
CREB |
phosphorylation |
Ser133 |
human |
ovarian cancer |
OVCAR-3 |
roflumilast |
increase |
5.0 |
30069985 |
acc0547 |
CREB |
phosphorylation |
Ser133 |
human |
ovarian cancer |
SK-OV-3 |
roflumilast |
increase |
5.0 |
30069985 |
acc0548 |
MAP4 |
phosphorylation |
Ser696 |
human |
ovarian cancer |
HeyA8 |
paclitaxel |
inhibit |
5.0 |
30084832 |
acc0549 |
MAP4 |
phosphorylation |
Ser696 |
human |
ovarian cancer |
OVCAR5 |
paclitaxel |
inhibit |
5.0 |
30084832 |
acc0550 |
FAK |
phosphorylation |
Tyr397 |
human |
gastric cancer |
GIST882 |
imatinib |
inhibit |
5.0 |
30149002 |
acc0551 |
UVRAG |
ubiquitination |
Lys517 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc0552 |
UVRAG |
ubiquitination |
Lys599 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc0553 |
UVRAG |
phosphorylation |
Ser522 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc0554 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR8-TR |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc0555 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
ovarian cancer |
OVCAR8-TR |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc0556 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
ovarian cancer |
A2780cp70 |
Cisplatin |
inhibit |
5.0 |
18587580 |
acc0557 |
Src |
phosphorylation |
Tyr416 |
human |
ovarian cancer |
A2780cp70 |
Cisplatin |
inhibit |
5.0 |
18587580 |
acc0558 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
ovarian cancer |
OVCAR8-TR |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc0559 |
Src |
phosphorylation |
Tyr416 |
human |
ovarian cancer |
OVCAR8-TR |
CDDO-Me |
inhibit |
5.0 |
18587580 |
acc0560 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR8-TR |
paclitaxel |
inhibit |
5.0 |
18587580 |
acc0561 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
ovarian cancer |
OVCAR8-TR |
paclitaxel |
inhibit |
5.0 |
18587580 |
acc0562 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
ovarian cancer |
OVCAR8-TR |
paclitaxel |
inhibit |
5.0 |
18587580 |
acc0563 |
Src |
phosphorylation |
Tyr416 |
human |
ovarian cancer |
OVCAR8-TR |
paclitaxel |
inhibit |
5.0 |
18587580 |
acc0564 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
A2780cp70 |
Cisplatin |
inhibit |
5.0 |
18587580 |
acc0565 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
ovarian cancer |
A2780cp70 |
Cisplatin |
inhibit |
5.0 |
18587580 |
acc0566 |
beta-catenin |
phosphorylation |
Ser33 |
human |
lung cancer |
A549 |
CGK062 |
modulate |
4.0 |
30968157 |
acc0567 |
beta-catenin |
phosphorylation |
Ser37 |
human |
lung cancer |
A549 |
CGK062 |
modulate |
4.0 |
30968157 |
acc0568 |
DRP1 |
phosphorylation |
Ser637 |
human |
breast cancer |
MCF7 |
silibinin |
modulate |
4.0 |
31085166 |
acc0569 |
DRP1 |
phosphorylation |
Ser637 |
human |
breast cancer |
MDA-MB-231 |
silibinin |
modulate |
4.0 |
31085166 |
acc0570 |
eIF2a |
phosphorylation |
Ser51 |
human |
prostate cancer |
PC3 |
EPHB4 KO |
modulate |
3.0 |
31641103 |
acc0571 |
eIF2a |
phosphorylation |
Ser51 |
human |
prostate cancer |
22Rv1 |
EPHB4 KO |
modulate |
3.0 |
31641103 |
acc0572 |
Beclin-1 |
phosphorylation |
Ser15 |
human |
leukemia |
K562 |
promethazine |
modulate |
4.0 |
31682805 |
acc0573 |
mTOR |
phosphorylation |
Ser2448 |
human |
leukemia |
K562 |
promethazine |
modulate |
4.0 |
31682805 |
acc0574 |
EGFR |
phosphorylation |
Thr654 |
human |
skin cancer |
A431 |
AnxA6 expression |
modulate |
3.0 |
31869496 |
acc0575 |
EGFR |
phosphorylation |
Thr654 |
human |
skin cancer |
A431 |
erlotinib |
promote |
5.0 |
31869496 |
acc0576 |
EGFR |
phosphorylation |
Thr654 |
human |
skin cancer |
A431 |
gefitinib |
promote |
5.0 |
31869496 |
acc0577 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HCT116 |
convallatoxin |
modulate |
4.0 |
32004989 |
acc0578 |
STAT3 |
phosphorylation |
Ser727 |
human |
colorectal cancer |
HCT116 |
convallatoxin |
modulate |
4.0 |
32004989 |
acc0579 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR-3 |
curcumin |
modulate |
4.0 |
19647363 |
acc0580 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
PA-1 |
curcumin |
modulate |
4.0 |
19647363 |
acc0581 |
EphA2 |
phosphorylation |
Ser897 |
human |
ovarian cancer |
OVCAR4 |
platinum |
inhibit |
5.0 |
32115889 |
acc0582 |
EphA2 |
phosphorylation |
Tyr558 |
human |
ovarian cancer |
OVCAR4 |
platinum |
promote |
5.0 |
32115889 |
acc0583 |
EphA2 |
phosphorylation |
Ser897 |
human |
ovarian cancer |
OVCAR8 |
platinum |
inhibit |
5.0 |
32115889 |
acc0584 |
EphA2 |
phosphorylation |
Tyr558 |
human |
ovarian cancer |
OVCAR8 |
platinum |
promote |
5.0 |
32115889 |
acc0585 |
PHB |
phosphorylation |
Tyr259 |
human |
ovarian cancer |
SK-OV-3 |
platinum |
inhibit |
5.0 |
32169072 |
acc0586 |
PHB |
phosphorylation |
Tyr259 |
human |
ovarian cancer |
KURAMOCHI |
platinum |
inhibit |
5.0 |
32169072 |
acc0587 |
DHX9 |
phosphorylation |
Ser321 |
human |
colorectal cancer |
HCT116 |
oxaliplatin (OXA) |
inhibit |
5.0 |
32187976 |
acc0588 |
PHB1 |
phosphorylation |
Thr258 |
human |
colorectal cancer |
RKO |
FL3 |
modulate |
4.0 |
32665357 |
acc0589 |
PHB1 |
phosphorylation |
Thr258 |
human |
colorectal cancer |
HCT116 |
FL3 |
modulate |
4.0 |
32665357 |
acc0590 |
PHB1 |
phosphorylation |
Thr258 |
human |
colorectal cancer |
SW48 |
FL3 |
modulate |
4.0 |
32665357 |
acc0591 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
PANC-1 |
curcumin |
modulate |
4.0 |
20121547 |
acc0592 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
AsPC-1 |
curcumin |
modulate |
4.0 |
20121547 |
acc0593 |
MDM2 |
phosphorylation |
unclear |
human |
pancreas cancer |
SW1990 |
sodium cantharidinate |
modulate |
4.0 |
33165811 |
acc0594 |
P53 |
phosphorylation |
Ser315 |
human |
pancreas cancer |
SW1990 |
sodium cantharidinate |
modulate |
4.0 |
33165811 |
acc0595 |
TBK1 |
phosphorylation |
Ser172 |
mouse |
colon cancer |
MC38 |
ionizing radiation |
increase |
5.0 |
33496784 |
acc0596 |
IRF3 |
phosphorylation |
Ser396 |
mouse |
colon cancer |
MC38 |
ionizing radiation |
increase |
5.0 |
33496784 |
acc0597 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
BxPC-3 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0598 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0599 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
PANC-1 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0600 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
MIA PaCa-2 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0601 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
MIA PaCa-2 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0602 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0603 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0604 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
MIA PaCa-2 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0605 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
BxPC-3 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0606 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
BxPC-3 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0607 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
BxPC-3 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0608 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
BxPC-3 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0609 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
PANC-1 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0610 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
PANC-1 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0611 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
PANC-1 |
erlotinib |
inhibit |
5.0 |
33614917 |
acc0612 |
EGFR |
phosphorylation |
Tyr1068 |
human |
ovarian cancer |
A2780/DDP |
DDP |
inhibit |
5.0 |
33794187 |
acc0613 |
EGFR |
phosphorylation |
Tyr1068 |
human |
ovarian cancer |
COC1/DDP |
DDP |
inhibit |
5.0 |
33794187 |
acc0614 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
Hep3B |
FLLL32 |
modulate |
4.0 |
20818158 |
acc0615 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-398 |
FLLL32 |
modulate |
4.0 |
20818158 |
acc0616 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0617 |
Src |
phosphorylation |
Tyr416 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0618 |
p38MAPK |
phosphorylation |
Tyr180 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0619 |
p38MAPK |
phosphorylation |
Tyr182 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0620 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0621 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0622 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0623 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0624 |
p38MAPK |
phosphorylation |
Tyr180 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0625 |
p38MAPK |
phosphorylation |
Tyr182 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0626 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0627 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0628 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0629 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0630 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0631 |
Src |
phosphorylation |
Tyr416 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
sorafenib + berbamine + ouabain |
modulate |
4.0 |
34233013 |
acc0632 |
ATR |
phosphorylation |
Ser/Thr |
human |
gastric cancer |
SUN638 |
olaparib |
inhibit |
5.0 |
34969765 |
acc0633 |
MAPK |
phosphorylation |
Thr180 |
human |
gastric cancer |
SUN638 |
olaparib |
inhibit |
5.0 |
34969765 |
acc0634 |
MAPK |
phosphorylation |
Tyr182 |
human |
gastric cancer |
SUN638 |
olaparib |
inhibit |
5.0 |
34969765 |
acc0635 |
Rock2 |
phosphorylation |
Ser1366 |
human |
renal cancer |
786-O |
sunitinib |
inhibit |
5.0 |
34974812 |
acc0636 |
Rock2 |
phosphorylation |
Ser1366 |
human |
renal cancer |
ACHN |
sunitinib |
inhibit |
5.0 |
34974812 |
acc0637 |
Rock2 |
phosphorylation |
Ser1366 |
human |
renal cancer |
786-O |
Everolimus |
inhibit |
5.0 |
34974812 |
acc0638 |
Rock2 |
phosphorylation |
Ser1366 |
human |
renal cancer |
ACHN |
Everolimus |
inhibit |
5.0 |
34974812 |
acc0639 |
JNK |
phosphorylation |
unclear |
human |
ovarian cancer |
A2780/DDP |
Cisplatin |
enhance |
5.0 |
35179434 |
acc0640 |
NT5C2 |
phosphorylation |
Ser502 |
human |
leukemia |
Jurkat |
6-MP |
inhibit |
5.0 |
35984649 |
acc0641 |
STAT3 |
phosphorylation |
Tyr705 |
human |
renal cancer |
SK-RC-45 |
FLLL32 |
modulate |
4.0 |
22899991 |
acc0642 |
STAT3 |
phosphorylation |
Tyr705 |
human |
renal cancer |
SK-RC-54 |
FLLL32 |
modulate |
4.0 |
22899991 |
acc0643 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
A375 |
FLLL32 |
modulate |
4.0 |
22899991 |
acc0644 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
Hs294T |
FLLL32 |
modulate |
4.0 |
22899991 |
acc0645 |
STAT3 |
phosphorylation |
Tyr705 |
human |
renal cancer |
SK-RC-45 |
FLLL62 |
modulate |
4.0 |
22899991 |
acc0646 |
STAT3 |
phosphorylation |
Tyr705 |
human |
renal cancer |
SK-RC-54 |
FLLL62 |
modulate |
4.0 |
22899991 |
acc0647 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
A375 |
FLLL62 |
modulate |
4.0 |
22899991 |
acc0648 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
Hs294T |
FLLL62 |
modulate |
4.0 |
22899991 |
acc0649 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
Paca44 |
gemcitabine |
inhibit |
5.0 |
24953430 |
acc0650 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
A1847 |
AZD1480 |
modulate |
4.0 |
25646015 |
acc0651 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR5 |
AZD1480 |
modulate |
4.0 |
25646015 |
acc0652 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR-8 |
AZD1480 |
modulate |
4.0 |
25646015 |
acc0653 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
ovarian cancer |
MOVCAR-5009 |
AZD1480 |
modulate |
4.0 |
25646015 |
acc0654 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
ovarian cancer |
MOVCAR-5447 |
AZD1480 |
modulate |
4.0 |
25646015 |
acc0655 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
CAOV3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0656 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0657 |
PI3K |
phosphorylation |
Tyr458 |
human |
ovarian cancer |
SK-OV-3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0658 |
PI3K |
phosphorylation |
Tyr199 |
human |
ovarian cancer |
SK-OV-3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0659 |
PI3K |
phosphorylation |
Tyr458 |
human |
ovarian cancer |
CAOV3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0660 |
PI3K |
phosphorylation |
Tyr199 |
human |
ovarian cancer |
CAOV3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0661 |
PI3K |
phosphorylation |
Tyr458 |
human |
ovarian cancer |
SK-OV-3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0662 |
PI3K |
phosphorylation |
Tyr199 |
human |
ovarian cancer |
SK-OV-3 |
LY294002 |
modulate |
4.0 |
36625999 |
acc0663 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
CAOV3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0664 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0665 |
PI3K |
phosphorylation |
Tyr458 |
human |
ovarian cancer |
CAOV3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0666 |
PI3K |
phosphorylation |
Tyr199 |
human |
ovarian cancer |
CAOV3 |
sh-TRAF4 |
modulate |
3.0 |
36625999 |
acc0667 |
Chk1 |
phosphorylation |
Ser345 |
human |
colorectal cancer |
HT29 |
AZD6738 + FTD |
modulate |
4.0 |
36734271 |
acc0668 |
Chk1 |
phosphorylation |
Ser345 |
human |
colorectal cancer |
HT116 |
AZD6738 + FTD |
modulate |
4.0 |
36734271 |
acc0669 |
Chk1 |
phosphorylation |
Ser345 |
human |
colorectal cancer |
HT29 |
FTD |
inhibit |
5.0 |
36734271 |
acc0670 |
Chk1 |
phosphorylation |
Ser345 |
human |
colorectal cancer |
HT116 |
FTD |
inhibit |
5.0 |
36734271 |
acc0671 |
DRP1 |
phosphorylation |
Ser616 |
human |
oral cancer |
CAL27 |
alantolactone |
modulate |
4.0 |
37198593 |
acc0672 |
DRP1 |
phosphorylation |
Ser616 |
human |
oral cancer |
SCC9 |
alantolactone |
modulate |
4.0 |
37198593 |
acc0673 |
FAK |
phosphorylation |
Tyr397 |
human |
ovarian cancer |
SK-OV-3 |
C1632 |
modulate |
4.0 |
37541366 |
acc0674 |
YAP |
phosphorylation |
Ser127 |
human |
ovarian cancer |
A2780 |
Cisplatin |
inhibit |
5.0 |
37828220 |
acc0675 |
YAP |
phosphorylation |
Ser127 |
human |
ovarian cancer |
ES-2 |
Cisplatin |
inhibit |
5.0 |
37828220 |
acc0676 |
RUNX1 |
phosphorylation |
Ser94 |
human |
leukemia |
|
imatinib |
inhibit |
5.0 |
37903788 |
acc0677 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
|
imatinib |
inhibit |
5.0 |
37903788 |
acc0678 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
HGC-27 |
Lactate |
modulate |
4.0 |
37968076 |
acc0679 |
HMGB1 |
phosphorylation |
unclear |
human |
gastric cancer |
HGC-27 |
Lactate |
modulate |
4.0 |
37968076 |
acc0680 |
p125FAK |
phosphorylation |
Tyr397 |
mouse |
Mouse Embryonic Fibroblast |
Swiss 3T3 |
thapsigargin |
modulate |
3.0 |
8314789 |
acc0681 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
253J B-V |
CGP 54211 |
modulate |
4.0 |
9815668 |
acc0682 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
5637 |
CGP 54211 |
modulate |
4.0 |
9815668 |
acc0683 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
TCC |
CGP 54211 |
modulate |
4.0 |
9815668 |
acc0684 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
T24 |
CGP 54211 |
modulate |
4.0 |
9815668 |
acc0685 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
RT4 |
CGP 54211 |
modulate |
4.0 |
9815668 |
acc0686 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
253J B-V |
CGP 53353 |
modulate |
4.0 |
9815668 |
acc0687 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
5637 |
CGP 53353 |
modulate |
4.0 |
9815668 |
acc0688 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
TCC |
CGP 53353 |
modulate |
4.0 |
9815668 |
acc0689 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
T24 |
CGP 53353 |
modulate |
4.0 |
9815668 |
acc0690 |
EGFR |
phosphorylation |
Tyr |
human |
bladder cancer |
RT4 |
CGP 53353 |
modulate |
4.0 |
9815668 |
acc0691 |
KRAS |
prenylation |
Cys186 |
human |
colorectal cancer |
LoVo |
L-OHP |
inhibit |
5.0 |
37069612 |
acc0692 |
KRAS |
prenylation |
Cys186 |
human |
colorectal cancer |
Colon-26 |
L-OHP |
inhibit |
5.0 |
37069612 |
acc0693 |
GLI2 |
ubiquitination |
unclear |
human |
myeloma |
MM.1S |
bortezomib |
enhance |
5.0 |
34546340 |
acc0694 |
GLI2 |
ubiquitination |
unclear |
human |
myeloma |
OPM-2 |
bortezomib |
enhance |
5.0 |
34546340 |
acc0695 |
EGFR |
ubiquitination |
unclear |
human |
colorectal cancer |
DiFi5 |
cetuximab |
inhibit |
5.0 |
17804738 |
acc0696 |
EGFR |
phosphorylation |
Tyr845 |
human |
colorectal cancer |
DiFi5 |
cetuximab |
inhibit |
5.0 |
17804738 |
acc0697 |
FOXM1 |
ubiquitination |
unclear |
human |
pancreas cancer |
BxPC-3 |
gemcitabine |
enhance |
5.0 |
31598398 |
acc0698 |
FOXM1 |
ubiquitination |
unclear |
human |
pancreas cancer |
SW1990 |
gemcitabine |
enhance |
5.0 |
31598398 |
acc0699 |
IGF2BP3 |
ubiquitination |
unclear |
human |
colorectal cancer |
HCT116 |
Berberine |
modulate |
4.0 |
36822301 |
acc0700 |
IGF2BP3 |
ubiquitination |
unclear |
human |
colorectal cancer |
SW620 |
Berberine |
modulate |
4.0 |
36822301 |
acc0701 |
SIRT7 |
ubiquitination |
unclear |
human |
hepatocellular carcinoma |
Hep3B |
sorafenib |
promote |
5.0 |
37187452 |
acc0702 |
SIRT7 |
ubiquitination |
unclear |
human |
hepatocellular carcinoma |
SNU-449 |
sorafenib |
promote |
5.0 |
37187452 |
acc0703 |
AKT |
ubiquitination |
unclear |
human |
gastric cancer |
MGC803 |
Estradiol cypionate |
modulate |
4.0 |
37392652 |
acc0704 |
AKT |
ubiquitination |
unclear |
human |
gastric cancer |
SGC7901 |
Estradiol cypionate |
modulate |
4.0 |
37392652 |
acc0705 |
beta-catenin |
ubiquitination |
unclear |
human |
pancreas cancer |
MIA PaCa-2 |
niclosamide + gemcitabine |
modulate |
4.0 |
37917550 |
acc0706 |
4EBP1 |
phosphorylation |
Thr37 |
human |
lung cancer |
NCI-H196 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0707 |
4EBP1 |
phosphorylation |
Thr37 |
human |
glioblastoma |
SNB-75 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0708 |
4EBP1 |
phosphorylation |
Thr37 |
human |
glioblastoma |
SF-539 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0709 |
4EBP1 |
phosphorylation |
Thr37 |
human |
glioblastoma |
U87-MG |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0710 |
4EBP1 |
phosphorylation |
Thr46 |
human |
lung cancer |
NCI-H196 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0711 |
4EBP1 |
phosphorylation |
Thr46 |
human |
glioblastoma |
SNB-75 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0712 |
4EBP1 |
phosphorylation |
Thr46 |
human |
glioblastoma |
SF-539 |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0713 |
4EBP1 |
phosphorylation |
Thr46 |
human |
glioblastoma |
U87-MG |
Olaparib |
inhibit |
5.0 |
30201826 |
acc0714 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
SK-BR-3 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0715 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SK-BR-3 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0716 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
MCF7 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0717 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0718 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
HER2-18 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0719 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
HER2-18 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0720 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
BT474 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0721 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
BT474 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0722 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
MDA-MB-231 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0723 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
MLN0128 + TSA |
modulate |
4.0 |
24562770 |
acc0724 |
histone H3 |
acetylation |
Lys9 |
human |
colorectal cancer |
HCT116 |
CUDC-907 |
enhance |
4.0 |
28139498 |
acc0725 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HCT116 |
CUDC-907 |
reduce |
5.0 |
28139498 |
acc0726 |
Hsp90 |
acetylation |
lys |
human |
breast cancer |
SK-BR-3 |
trastuzumab |
enhance |
5.0 |
21082217 |
acc0727 |
alpha-tubulin |
acetylation |
lys |
human |
breast cancer |
SK-BR-3 |
geldanamycin |
enhance |
5.0 |
21082217 |
acc0728 |
CCAR2 |
acetylation |
Lys |
human |
colorectal cancer |
HCT116 |
sulforaphane |
modulate |
4.0 |
30643017 |
acc0729 |
RelA |
acetylation |
Lys310 |
human |
breast cancer |
MDA-MB-231 |
BRD4 inhibitor 13a |
modulate |
4.0 |
34378541 |
acc0730 |
FOXO1 |
acetylation |
Lys |
human |
lung cancer |
PC9 |
depsipeptide + Erlotinib |
modulate |
4.0 |
26036758 |
acc0731 |
FOXO1 |
acetylation |
Lys |
human |
lung cancer |
H1650 |
depsipeptide + Erlotinib |
modulate |
4.0 |
26036758 |
acc0732 |
FOXO1 |
acetylation |
Thr24 |
human |
lung cancer |
PC9 |
Ku0063794 + Erlotinib |
modulate |
4.0 |
26036758 |
acc0733 |
FOXO1 |
acetylation |
Thr24 |
human |
lung cancer |
H1650 |
Ku0063794 + Erlotinib |
modulate |
4.0 |
26036758 |
acc0734 |
FOXO1 |
acetylation |
Lys |
human |
lung cancer |
PC9 |
LY294002 + Erlotinib |
modulate |
4.0 |
26036758 |
acc0735 |
FOXO1 |
acetylation |
Lys |
human |
lung cancer |
H1650 |
LY294002 + Erlotinib |
modulate |
4.0 |
26036758 |
acc0736 |
GD3 |
acetylation |
unclear |
human |
medulloblastoma |
RES256 |
etoposide |
inhibit |
5.0 |
31197190 |
acc0737 |
GLDC |
acetylation |
Lys514 |
human |
glioblastoma |
U251 |
rapamycin |
modulate |
4.0 |
34244482 |
acc0738 |
GLDC |
acetylation |
Lys514 |
human |
glioblastoma |
U87 |
rapamycin |
modulate |
4.0 |
34244482 |
acc0739 |
ERalpha |
methylation |
unclear |
human |
breast cancer |
MCF7 |
tamoxifen |
modulate |
4.0 |
37458145 |
acc0740 |
6PGD |
methylation |
Arg324 |
human |
lung cancer |
|
Cisplatin |
inhibit |
5.0 |
36815049 |
acc0741 |
ENO1 |
methylation |
Arg9 |
human |
lung cancer |
|
Cisplatin |
inhibit |
5.0 |
36815049 |
acc0742 |
ENO1 |
methylation |
Arg372 |
human |
lung cancer |
|
Cisplatin |
inhibit |
5.0 |
36815049 |
acc0743 |
AR |
acetylation |
Lys609 |
human |
prostate cancer |
C4-2B |
(R)-9b |
modulate |
4.0 |
35704598 |
acc0744 |
AR |
phosphorylation |
Tyr267 |
human |
prostate cancer |
C4-2B |
(R)-9b |
modulate |
4.0 |
35704598 |
acc0745 |
AKT |
phosphorylation |
Ser473 |
human |
cholangiocarcinoma |
QBC939 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0746 |
S6 |
phosphorylation |
Ser235 |
human |
cholangiocarcinoma |
QBC939 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0747 |
S6 |
phosphorylation |
Ser236 |
human |
cholangiocarcinoma |
QBC939 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0748 |
AKT |
phosphorylation |
Ser473 |
human |
cholangiocarcinoma |
SK-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0749 |
S6 |
phosphorylation |
Ser235 |
human |
cholangiocarcinoma |
SK-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0750 |
S6 |
phosphorylation |
Ser236 |
human |
cholangiocarcinoma |
SK-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0751 |
AKT |
phosphorylation |
Ser473 |
human |
cholangiocarcinoma |
MZ-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0752 |
S6 |
phosphorylation |
Ser235 |
human |
cholangiocarcinoma |
MZ-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0753 |
S6 |
phosphorylation |
Ser236 |
human |
cholangiocarcinoma |
MZ-ChA-1 |
5-FU |
inhibit |
5.0 |
25933112 |
acc0754 |
PLCgamma2 |
phosphorylation |
Tyr759 |
human |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0755 |
PLCgamma2 |
phosphorylation |
Tyr1217 |
mouse |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0756 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0757 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0758 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0759 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0760 |
BTK |
phosphorylation |
Tyr223 |
mouse |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0761 |
S6 |
phosphorylation |
Ser235 |
mouse |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0762 |
S6 |
phosphorylation |
Ser236 |
mouse |
leukemia |
|
acalabrutinib |
modulate |
4.0 |
27903679 |
acc0763 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
Afatinib |
modulate |
4.0 |
32978518 |
acc0764 |
EGFR |
phosphorylation |
Tyr1068 |
human |
prostate cancer |
PC3 |
Afatinib |
modulate |
4.0 |
32978518 |
acc0765 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
DU145 |
Afatinib |
modulate |
4.0 |
32978518 |
acc0766 |
EGFR |
phosphorylation |
Tyr1068 |
human |
prostate cancer |
DU145 |
Afatinib |
modulate |
4.0 |
32978518 |
acc0767 |
FRS2alpha |
phosphorylation |
unclear |
human |
breast cancer |
SUM 52PE |
Alofanib |
modulate |
4.0 |
27136102 |
acc0768 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
BC |
anthracyclines |
no effect |
2.0 |
17804473 |
acc0769 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
apigenin |
modulate |
4.0 |
17961621 |
acc0770 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
apigenin |
modulate |
4.0 |
17961621 |
acc0771 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
apigenin |
modulate |
4.0 |
17961621 |
acc0772 |
Smad2 |
phosphorylation |
Ser465 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0773 |
Smad2 |
phosphorylation |
Ser465 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0774 |
FAK |
phosphorylation |
Tyr576 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0775 |
FAK |
phosphorylation |
Tyr576 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0776 |
FAK |
phosphorylation |
Tyr577 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0777 |
FAK |
phosphorylation |
Tyr577 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0778 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0779 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0780 |
Smad3 |
phosphorylation |
Ser423 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0781 |
Smad3 |
phosphorylation |
Ser423 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0782 |
Smad2 |
phosphorylation |
Ser467 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0783 |
Smad2 |
phosphorylation |
Ser467 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0784 |
Smad3 |
phosphorylation |
Ser425 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0785 |
Smad3 |
phosphorylation |
Ser425 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0786 |
Src |
phosphorylation |
Tyr416 |
human |
prostate cancer |
PC3-M |
apigenin |
modulate |
4.0 |
23359392 |
acc0787 |
Src |
phosphorylation |
Tyr416 |
human |
prostate cancer |
LNCaP C4-2B |
apigenin |
modulate |
4.0 |
23359392 |
acc0788 |
FOXO3a |
phosphorylation |
Thr32 |
human |
hepatocellular carcinoma |
HepG2 |
As(2)O(3) |
modulate |
4.0 |
18937079 |
acc0789 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H1993 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0790 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H1993 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0791 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H1975 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0792 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H1975 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0793 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1993 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0794 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1975 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0795 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H460 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0796 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H1993 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0797 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H1993 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0798 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H460 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0799 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H460 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0800 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H460 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0801 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H460 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0802 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H1975 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0803 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H1975 |
AZD6244 + BEZ235 |
modulate |
4.0 |
24939055 |
acc0804 |
HER2 |
phosphorylation |
Tyr1221 |
human |
breast cancer |
BT474c |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0805 |
HER2 |
phosphorylation |
Tyr1221 |
human |
breast cancer |
HCC1954 |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0806 |
HER2 |
phosphorylation |
Tyr1222 |
human |
breast cancer |
BT474c |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0807 |
HER2 |
phosphorylation |
Tyr1222 |
human |
breast cancer |
HCC1954 |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0808 |
HER3 |
phosphorylation |
Tyr1289 |
human |
breast cancer |
BT474c |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0809 |
HER3 |
phosphorylation |
Tyr1289 |
human |
breast cancer |
HCC1954 |
AZD5363 |
inhibit |
5.0 |
26095475 |
acc0810 |
RAF |
phosphorylation |
Ser338 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0811 |
RAF |
phosphorylation |
Ser338 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0812 |
ERK2 |
phosphorylation |
Thr185 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0813 |
ERK2 |
phosphorylation |
Thr185 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0814 |
ERK2 |
phosphorylation |
Tyr187 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0815 |
ERK2 |
phosphorylation |
Tyr187 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0816 |
MEK |
phosphorylation |
Ser217 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0817 |
MEK |
phosphorylation |
Ser217 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0818 |
MEK |
phosphorylation |
Ser221 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0819 |
MEK |
phosphorylation |
Ser221 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0820 |
ERK1 |
phosphorylation |
Thr202 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0821 |
ERK1 |
phosphorylation |
Thr202 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0822 |
ERK1 |
phosphorylation |
Tyr204 |
human |
glioblastoma |
U87 |
berberine |
modulate |
4.0 |
25504754 |
acc0823 |
ERK1 |
phosphorylation |
Tyr204 |
human |
glioblastoma |
U251 |
berberine |
modulate |
4.0 |
25504754 |
acc0824 |
Ezrin |
phosphorylation |
Thr567 |
human |
nasopharyngeal carcinoma |
5-8F |
berberine |
modulate |
4.0 |
19651779 |
acc0825 |
AKT |
phosphorylation |
Ser473 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0826 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0827 |
S6 |
phosphorylation |
Thr389 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0828 |
S6 |
phosphorylation |
Thr389 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0829 |
AKT |
phosphorylation |
Ser473 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0830 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0831 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0832 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0833 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0834 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0835 |
ERK1 |
phosphorylation |
Thr202 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0836 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0837 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0838 |
ERK2 |
phosphorylation |
Thr185 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0839 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0840 |
S6 |
phosphorylation |
Thr389 |
human |
colon cancer |
COLO205 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0841 |
S6 |
phosphorylation |
Thr389 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29296217 |
acc0842 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0843 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0844 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0845 |
ERK1 |
phosphorylation |
Thr202 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0846 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0847 |
ERK2 |
phosphorylation |
Thr185 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0848 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colon cancer |
COLO205 |
trametinib |
inhibit |
5.0 |
29296217 |
acc0849 |
AKT |
phosphorylation |
Ser473 |
rat |
pituitary tumor |
GH3 |
BKM120 |
modulate |
4.0 |
26983879 |
acc0850 |
AKT |
phosphorylation |
Ser473 |
rat |
pituitary tumor |
GH3 |
BEZ235 |
modulate |
4.0 |
26983879 |
acc0851 |
S6 |
phosphorylation |
Ser235 |
rat |
pituitary tumor |
GH3 |
BEZ235 |
modulate |
4.0 |
26983879 |
acc0852 |
S6 |
phosphorylation |
Ser236 |
rat |
pituitary tumor |
GH3 |
BEZ235 |
modulate |
4.0 |
26983879 |
acc0853 |
mTOR |
phosphorylation |
Ser2448 |
rat |
pituitary tumor |
GH3 |
BEZ235 |
modulate |
4.0 |
26983879 |
acc0854 |
AKT |
phosphorylation |
Ser473 |
mouse |
neuroblastoma |
TBJ |
bortezomib |
modulate |
4.0 |
16670342 |
acc0855 |
AKT |
phosphorylation |
Ser473 |
mouse |
neuroblastoma |
Neuro-2a |
bortezomib |
modulate |
4.0 |
16670342 |
acc0856 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
MV4-11 |
cabozantinib |
modulate |
4.0 |
30862120 |
acc0857 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
MV4-11 |
MK2206 |
modulate |
4.0 |
30862120 |
acc0858 |
Chk1 |
phosphorylation |
Ser345 |
mouse |
skin cancer |
SKH-1 mice |
caffeine |
modulate |
4.0 |
18381462 |
acc0859 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H82 |
calcium |
modulate |
4.0 |
17440109 |
acc0860 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H82 |
calcium |
modulate |
4.0 |
17440109 |
acc0861 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H82 |
calcium |
modulate |
4.0 |
17440109 |
acc0862 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H82 |
calcium |
modulate |
4.0 |
17440109 |
acc0863 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H82 |
calcium |
modulate |
4.0 |
17440109 |
acc0864 |
beta-catenin |
phosphorylation |
Ser33 |
human |
hepatocellular carcinoma |
HuH-7 |
Canagliflozin |
modulate |
4.0 |
31142735 |
acc0865 |
beta-catenin |
phosphorylation |
Ser37 |
human |
hepatocellular carcinoma |
HuH-7 |
Canagliflozin |
modulate |
4.0 |
31142735 |
acc0866 |
beta-catenin |
phosphorylation |
Thr41 |
human |
hepatocellular carcinoma |
HuH-7 |
Canagliflozin |
modulate |
4.0 |
31142735 |
acc0867 |
beta-catenin |
phosphorylation |
Ser45 |
human |
hepatocellular carcinoma |
HuH-7 |
Canagliflozin |
modulate |
4.0 |
31142735 |
acc0868 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
PANC-1 |
radiotherapy |
inhibit |
4.5 |
26887043 |
acc0869 |
AKT |
phosphorylation |
Ser473 |
human |
melanoma |
A375 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0870 |
AKT |
phosphorylation |
Ser473 |
human |
melanoma |
SK-MEL-5 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0871 |
AKT |
phosphorylation |
Thr308 |
human |
melanoma |
A375 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0872 |
AKT |
phosphorylation |
Thr308 |
human |
melanoma |
SK-MEL-5 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0873 |
PTEN |
phosphorylation |
Ser380 |
human |
melanoma |
A375 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0874 |
PTEN |
phosphorylation |
Ser380 |
human |
melanoma |
SK-MEL-5 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0875 |
PTEN |
phosphorylation |
Thr382 |
human |
melanoma |
A375 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0876 |
PTEN |
phosphorylation |
Thr382 |
human |
melanoma |
SK-MEL-5 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0877 |
PTEN |
phosphorylation |
Thr383 |
human |
melanoma |
A375 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0878 |
PTEN |
phosphorylation |
Thr383 |
human |
melanoma |
SK-MEL-5 |
chondroitin-4-sulfate(CHSA) |
modulate |
4.0 |
29547721 |
acc0879 |
AKT |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
HEY |
Cisplatin |
inhibit |
5.0 |
31597912 |
acc0880 |
AKT |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
SK-OV-3 |
Cisplatin |
inhibit |
5.0 |
31597912 |
acc0881 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MCF7/MDR |
Cisplatin |
inhibit |
5.0 |
31006103 |
acc0882 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
ES-2 |
Goserelin |
modulate |
4.0 |
23684357 |
acc0883 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3-ip |
Goserelin |
modulate |
4.0 |
23684357 |
acc0884 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
J82 |
Cisplatin |
inhibit |
5.0 |
28178653 |
acc0885 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
BIU-87 |
Cisplatin |
inhibit |
5.0 |
28178653 |
acc0886 |
FOXO3a |
phosphorylation |
Thr32 |
human |
lung cancer |
A549 |
Cisplatin |
modulate |
4.0 |
24814195 |
acc0887 |
PI3K |
phosphorylation |
Tyr458 |
human |
lung cancer |
A549 |
Cisplatin |
modulate |
4.0 |
24814195 |
acc0888 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
Cisplatin |
modulate |
4.0 |
24814195 |
acc0889 |
Chk2 |
phosphorylation |
Thr68 |
human |
testicular cancer |
833K |
Cisplatin |
modulate |
4.0 |
20846399 |
acc0890 |
Chk2 |
phosphorylation |
Thr68 |
human |
testicular cancer |
SuSa |
Cisplatin |
modulate |
4.0 |
20846399 |
acc0891 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
SGC7901 |
Cisplatin |
inhibit |
5.0 |
32058824 |
acc0892 |
ERK1 |
phosphorylation |
Thr202 |
human |
osteosarcoma |
U2OS |
CQ-HES |
modulate |
4.0 |
28708385 |
acc0893 |
ERK1 |
phosphorylation |
Tyr204 |
human |
osteosarcoma |
U2OS |
CQ-HES |
modulate |
4.0 |
28708385 |
acc0894 |
ERK2 |
phosphorylation |
Thr185 |
human |
osteosarcoma |
U2OS |
CQ-HES |
modulate |
4.0 |
28708385 |
acc0895 |
ERK2 |
phosphorylation |
Tyr187 |
human |
osteosarcoma |
U2OS |
CQ-HES |
modulate |
4.0 |
28708385 |
acc0896 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
U2OS |
CQ-HES |
modulate |
4.0 |
28708385 |
acc0897 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0898 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0899 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0900 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0901 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0902 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0903 |
JNK |
phosphorylation |
Thr183 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0904 |
JNK |
phosphorylation |
Thr183 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0905 |
JNK |
phosphorylation |
Tyr185 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0906 |
JNK |
phosphorylation |
Tyr185 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0907 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0908 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0909 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0910 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0911 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0912 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0913 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SK-BR-3 |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0914 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
435eB |
curcumin + Tricostatin A £¨TSA£© |
modulate |
4.0 |
22290509 |
acc0915 |
rpS6 |
phosphorylation |
Ser235 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29777202 |
acc0916 |
rpS6 |
phosphorylation |
Ser236 |
human |
melanoma |
A375 |
dabrafenib |
inhibit |
5.0 |
29777202 |
acc0917 |
rpS6 |
phosphorylation |
Ser235 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29777202 |
acc0918 |
rpS6 |
phosphorylation |
Ser236 |
human |
melanoma |
A375 |
trametinib |
inhibit |
5.0 |
29777202 |
acc0919 |
SAMHD1 |
phosphorylation |
Thr592 |
human |
leukemia |
CD4+ T |
dasatinib |
modulate |
3.0 |
32828803 |
acc0920 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
H2286 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0921 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
HCC366 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0922 |
MET |
phosphorylation |
Tyr1234 |
human |
lung cancer |
H2286 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0923 |
MET |
phosphorylation |
Tyr1234 |
human |
lung cancer |
HCC366 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0924 |
MET |
phosphorylation |
Tyr1235 |
human |
lung cancer |
H2286 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0925 |
MET |
phosphorylation |
Tyr1235 |
human |
lung cancer |
HCC366 |
dasatinib |
inhibit |
5.0 |
25348954 |
acc0926 |
CAMKII |
phosphorylation |
Thr286 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0927 |
EGFR |
phosphorylation |
Tyr845 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0928 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0929 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0930 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0931 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT29 |
DCA |
modulate |
4.0 |
27086143 |
acc0932 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
PC3 |
delta-T |
modulate |
4.0 |
26465359 |
acc0933 |
Akt |
phosphorylation |
Ser473 |
human |
lung cancer |
NCI-H69 |
naltrindole |
modulate |
4.0 |
15574783 |
acc0934 |
Akt |
phosphorylation |
Thr308 |
human |
lung cancer |
NCI-H69 |
naltrindole |
modulate |
4.0 |
15574783 |
acc0935 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
BEL-7402 |
Forskolin |
modulate |
4.0 |
16177565 |
acc0936 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SMMC-7721 |
Forskolin |
modulate |
4.0 |
16177565 |
acc0937 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
BEL-7402 |
Forskolin |
modulate |
4.0 |
16177565 |
acc0938 |
AKT |
phosphorylation |
Thr308 |
human |
hepatocellular carcinoma |
SMMC-7721 |
Forskolin |
modulate |
4.0 |
16177565 |
acc0939 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
DU145 |
PHLDA3 OV |
modulate |
3.0 |
34303965 |
acc0940 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
PHLDA3 OV |
modulate |
3.0 |
34303965 |
acc0941 |
GSK-3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
DU145 |
PHLDA3 OV |
modulate |
3.0 |
34303965 |
acc0942 |
GSK-3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
PC3 |
PHLDA3 OV |
modulate |
3.0 |
34303965 |
acc0943 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
DU145 |
docetaxel |
suppress |
5.0 |
34303965 |
acc0944 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
docetaxel |
suppress |
5.0 |
34303965 |
acc0945 |
GSK-3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
DU145 |
docetaxel |
suppress |
5.0 |
34303965 |
acc0946 |
GSK-3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
PC3 |
docetaxel |
suppress |
5.0 |
34303965 |
acc0947 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
PANC-1 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0948 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
PANC-1 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0949 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0950 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0951 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0952 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0953 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0954 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0955 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0956 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0957 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0958 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
metformin |
modulate |
4.0 |
23437362 |
acc0959 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
MIA PaCa-2 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0960 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0961 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0962 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0963 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc0964 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0965 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0966 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0967 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0968 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0969 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0970 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
MIA PaCa-2 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0971 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0972 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0973 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0974 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0975 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0976 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
PP242 |
modulate |
4.0 |
23437362 |
acc0977 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0978 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0979 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0980 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
PANC-1 |
PP242 |
modulate |
4.0 |
23437362 |
acc0981 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
PANC-1 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0982 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0983 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0984 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0985 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0986 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0987 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0988 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0989 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0990 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0991 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0992 |
S6K |
phosphorylation |
Thr389 |
human |
pancreas cancer |
MIA PaCa-2 |
rapamycin |
modulate |
4.0 |
23437362 |
acc0993 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0994 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0995 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0996 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0997 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0998 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
PANC-1 |
KU63794 |
modulate |
4.0 |
23437362 |
acc0999 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
rapamycin |
modulate |
4.0 |
23437362 |
acc1000 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
MIA PaCa-2 |
rapamycin |
modulate |
4.0 |
23437362 |
acc1001 |
S6 |
phosphorylation |
Ser235 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc1002 |
S6 |
phosphorylation |
Ser236 |
human |
pancreas cancer |
PANC-1 |
metformin |
modulate |
4.0 |
23437362 |
acc1003 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
LNCaP-Bic |
sorafenib |
modulate |
4.0 |
22383427 |
acc1004 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3-DR |
sorafenib |
modulate |
4.0 |
22383427 |
acc1005 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
HL-60 |
Arachidonic acid(AA) + TPA |
modulate |
3.0 |
23490067 |
acc1006 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
HL-60 |
Arachidonic acid(AA) + TPA |
modulate |
3.0 |
23490067 |
acc1007 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
HL-60 |
Arachidonic acid(AA) + TPA |
modulate |
3.0 |
23490067 |
acc1008 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
HL-60 |
Arachidonic acid(AA) + TPA |
modulate |
3.0 |
23490067 |
acc1009 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
U1752 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1010 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
U1752 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1011 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
NCI-H292 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1012 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
NCI-H292 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1013 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
U1752 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1014 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
Calu-6 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1015 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
NCI-H292 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1016 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
U1752 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1017 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
U1752 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1018 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
Calu-6 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1019 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
Calu-6 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1020 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
Calu-6 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1021 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
Calu-6 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1022 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
NCI-H292 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1023 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
NCI-H292 |
erlotinib |
inhibit |
5.0 |
23923067 |
acc1024 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23872583 |
acc1025 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
11ÔÂ18ÈÕ |
erlotinib |
inhibit |
5.0 |
23872583 |
acc1026 |
Src |
phosphorylation |
Tyr416 |
human |
lung cancer |
PC9 |
erlotinib |
inhibit |
5.0 |
23872583 |
acc1027 |
Src |
phosphorylation |
Tyr416 |
human |
lung cancer |
11ÔÂ18ÈÕ |
erlotinib |
inhibit |
5.0 |
23872583 |
acc1028 |
beta-catenin |
phosphorylation |
Ser33 |
human |
hepatocellular carcinoma |
SMMC-7721 |
esculetin |
modulate |
4.0 |
28789402 |
acc1029 |
beta-catenin |
phosphorylation |
Ser37 |
human |
hepatocellular carcinoma |
SMMC-7721 |
esculetin |
modulate |
4.0 |
28789402 |
acc1030 |
beta-catenin |
phosphorylation |
Thr41 |
human |
hepatocellular carcinoma |
SMMC-7721 |
esculetin |
modulate |
4.0 |
28789402 |
acc1031 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
SQ20B |
radiation |
inhibit |
4.5 |
16166302 |
acc1032 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
T24 |
radiation |
inhibit |
4.5 |
16166302 |
acc1033 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
estradiol |
modulate |
4.0 |
17138652 |
acc1034 |
ErbB2 |
phosphorylation |
Tyr1248 |
human |
breast cancer |
MCF7 |
AG826 |
modulate |
4.0 |
17138652 |
acc1035 |
ErbB2 |
phosphorylation |
Tyr1248 |
human |
breast cancer |
MCF7 |
AG826 |
modulate |
4.0 |
17138652 |
acc1036 |
AKT |
phosphorylation |
Ser473 |
human |
esophageal cancer |
TE1 |
eupatilin |
modulate |
4.0 |
29693162 |
acc1037 |
ERK1 |
phosphorylation |
Thr202 |
human |
esophageal cancer |
TE1 |
eupatilin |
modulate |
4.0 |
29693162 |
acc1038 |
ERK1 |
phosphorylation |
Tyr204 |
human |
esophageal cancer |
TE1 |
eupatilin |
modulate |
4.0 |
29693162 |
acc1039 |
ERK2 |
phosphorylation |
Thr185 |
human |
esophageal cancer |
TE1 |
eupatilin |
modulate |
4.0 |
29693162 |
acc1040 |
ERK2 |
phosphorylation |
Tyr187 |
human |
esophageal cancer |
TE1 |
eupatilin |
modulate |
4.0 |
29693162 |
acc1041 |
AKT |
phosphorylation |
Ser473 |
rat |
pituitary tumor |
MMQ |
everolimus + cabergoline |
modulate |
4.0 |
35721701 |
acc1042 |
AKT |
phosphorylation |
Ser473 |
human |
pituitary tumor |
NF-PitNET |
everolimus + cabergoline |
modulate |
4.0 |
35721701 |
acc1043 |
AKT |
phosphorylation |
Ser473 |
mouse |
melanoma |
B16F10 |
fenofibrate |
inhibit |
5.0 |
16707598 |
acc1044 |
ERalpha |
phosphorylation |
Ser118 |
human |
endometrial cancer |
ECC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1045 |
ERalpha |
phosphorylation |
Ser118 |
human |
endometrial cancer |
USPC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1046 |
ERalpha |
phosphorylation |
Ser167 |
human |
endometrial cancer |
ECC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1047 |
ERalpha |
phosphorylation |
Ser167 |
human |
endometrial cancer |
USPC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1048 |
AKT |
phosphorylation |
Ser473 |
human |
endometrial cancer |
ECC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1049 |
AKT |
phosphorylation |
Ser473 |
human |
endometrial cancer |
USPC1 |
MPA |
inhibit |
5.0 |
23530112 |
acc1050 |
cdc2 |
phosphorylation |
Tyr15 |
human |
prostate cancer |
DU145 |
gallic acid |
modulate |
4.0 |
17172433 |
acc1051 |
cdc25A |
phosphorylation |
Ser17 |
human |
prostate cancer |
DU145 |
gallic acid |
modulate |
4.0 |
17172433 |
acc1052 |
cdc25C |
phosphorylation |
Ser216 |
human |
prostate cancer |
DU145 |
gallic acid |
modulate |
4.0 |
17172433 |
acc1053 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
imatinib + GNF5 |
modulate |
4.0 |
30671399 |
acc1054 |
EGFR |
phosphorylation |
Tyr845 |
human |
colorectal cancer |
SW620 |
ganglioside + CD82 OV |
modulate |
4.0 |
33000220 |
acc1055 |
EGFR |
phosphorylation |
Tyr1045 |
human |
colorectal cancer |
SW620 |
ganglioside + CD82 OV |
modulate |
4.0 |
33000220 |
acc1056 |
EGFR |
phosphorylation |
Tyr1173 |
human |
colorectal cancer |
SW620 |
ganglioside + CD82 OV |
modulate |
4.0 |
33000220 |
acc1057 |
ER |
phosphorylation |
Ser118 |
human |
breast cancer |
|
gefitinib + anastrozole |
modulate |
4.0 |
15925816 |
acc1058 |
EGFR |
phosphorylation |
Tyr845 |
human |
breast cancer |
|
gefitinib + anastrozole |
modulate |
4.0 |
15925816 |
acc1059 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SUM159 |
gefitinib |
inhibit |
5.0 |
21660955 |
acc1060 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SUM 149 |
gefitinib |
inhibit |
5.0 |
21660955 |
acc1061 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SUM229 |
gefitinib |
inhibit |
5.0 |
21660955 |
acc1062 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
XG-1 |
genistein |
modulate |
4.0 |
19107739 |
acc1063 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
RPMI8226 |
genistein |
modulate |
4.0 |
19107739 |
acc1064 |
histone H3 |
methylation |
Lys9 |
human |
prostate cancer |
LNCaP |
genistein |
modulate |
3.0 |
18431742 |
acc1065 |
histone H3 |
methylation |
Lys9 |
human |
prostate cancer |
PC3 |
genistein |
modulate |
3.0 |
18431742 |
acc1066 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1067 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1068 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1069 |
EGFR |
phosphorylation |
Tyr1069 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1070 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1071 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1072 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1073 |
EGFR |
phosphorylation |
Tyr1069 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1074 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1075 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1076 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1077 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
Hep3B |
glycyrrhizic acid |
modulate |
4.0 |
32054305 |
acc1078 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1079 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1080 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1081 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1082 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1083 |
JNK |
phosphorylation |
Thr183 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1084 |
JNK |
phosphorylation |
Tyr185 |
human |
leukemia |
CML-iPSCs |
imatinib |
inhibit |
5.0 |
22592606 |
acc1085 |
beta-catenin |
phosphorylation |
Ser33 |
mouse |
melanoma |
B16 |
imidazole |
modulate |
4.0 |
20604839 |
acc1086 |
beta-catenin |
phosphorylation |
Ser37 |
mouse |
melanoma |
B16 |
imidazole |
modulate |
4.0 |
20604839 |
acc1087 |
beta-catenin |
phosphorylation |
Thr41 |
mouse |
melanoma |
B16 |
imidazole |
modulate |
4.0 |
20604839 |
acc1088 |
BCL2 |
phosphorylation |
Ser70 |
human |
hepatocellular carcinoma |
BEL-7402 |
3-Bromopropionylamino benzoylurea (JIMB01) |
modulate |
4.0 |
12754105 |
acc1089 |
c-FLIP |
phosphorylation |
unclear |
human |
glioblastoma |
LN-Z2308 |
CH-11 |
inhibit |
5.0 |
17973862 |
acc1090 |
c-FLIP |
phosphorylation |
unclear |
human |
glioblastoma |
U138 |
CH-11 |
inhibit |
5.0 |
17973862 |
acc1091 |
c-FLIP |
phosphorylation |
unclear |
human |
melanoma |
WM278 |
CH-11 |
inhibit |
5.0 |
17973862 |
acc1092 |
c-FLIP |
phosphorylation |
unclear |
human |
melanoma |
WM35 |
CH-11 |
inhibit |
5.0 |
17973862 |
acc1093 |
AKT |
phosphorylation |
Ser473 |
human |
glioblastoma |
U87 |
KU-60019 |
no effect |
4.0 |
19808981 |
acc1094 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
25590338 |
acc1095 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
28744398 |
acc1096 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
28744398 |
acc1097 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
28744398 |
acc1098 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
28744398 |
acc1099 |
c-Myc |
phosphorylation |
Ser62 |
human |
breast cancer |
BT474 |
lapatinib |
inhibit |
5.0 |
28744398 |
acc1100 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1101 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1102 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1103 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1104 |
MEK1 |
phosphorylation |
Ser217 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1105 |
MEK1 |
phosphorylation |
Ser221 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1106 |
MEK2 |
phosphorylation |
Ser222 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1107 |
MEK2 |
phosphorylation |
Ser226 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1108 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1109 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1110 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1111 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1112 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1113 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1975 |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1114 |
MEK1 |
phosphorylation |
Ser217 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1115 |
MEK1 |
phosphorylation |
Ser221 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1116 |
MEK2 |
phosphorylation |
Ser222 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1117 |
MEK2 |
phosphorylation |
Ser226 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1118 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1119 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
PC-9/GR |
gefitinib + Lovastatin |
modulate |
4.0 |
29215723 |
acc1120 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
PJ-34 |
modulate |
4.0 |
21821012 |
acc1121 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
3-AB |
modulate |
4.0 |
21821012 |
acc1122 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
U2OS |
PJ-34 |
modulate |
4.0 |
21821012 |
acc1123 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
U2OS |
3-AB |
modulate |
4.0 |
21821012 |
acc1124 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H358 |
PJ-34 |
modulate |
4.0 |
21821012 |
acc1125 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H358 |
3-AB |
modulate |
4.0 |
21821012 |
acc1126 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
AsPC-1 |
Bazedoxifene |
modulate |
4.0 |
27535971 |
acc1127 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
HPAF-2 |
Bazedoxifene |
modulate |
4.0 |
27535971 |
acc1128 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
PANC-1 |
Bazedoxifene |
modulate |
4.0 |
27535971 |
acc1129 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
MKN45 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1130 |
AKT |
phosphorylation |
Ser473 |
human |
gastric cancer |
SGC7901 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1131 |
p70S6K |
phosphorylation |
Thr421 |
human |
gastric cancer |
MKN45 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1132 |
p70S6K |
phosphorylation |
Thr421 |
human |
gastric cancer |
SGC7901 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1133 |
p70S6K |
phosphorylation |
Ser424 |
human |
gastric cancer |
MKN45 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1134 |
p70S6K |
phosphorylation |
Ser424 |
human |
gastric cancer |
SGC7901 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1135 |
4EBP1 |
phosphorylation |
Thr70 |
human |
gastric cancer |
MKN45 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1136 |
4EBP1 |
phosphorylation |
Thr70 |
human |
gastric cancer |
SGC7901 |
5-aza |
inhibit |
5.0 |
18622747 |
acc1137 |
c-Raf |
phosphorylation |
Ser43 |
human |
hepatocellular carcinoma |
Hep3B |
vitamin K1 + sorafenib |
modulate |
4.0 |
21734462 |
acc1138 |
c-Raf |
phosphorylation |
Ser259 |
human |
hepatocellular carcinoma |
Hep3B |
vitamin K1 + sorafenib |
modulate |
4.0 |
21734462 |
acc1139 |
c-Met |
phosphorylation |
Tyr1349 |
human |
hepatocellular carcinoma |
Hep3B |
vitamin K1 + sorafenib |
modulate |
4.0 |
21734462 |
acc1140 |
AKT |
phosphorylation |
Thr308 |
human |
ovarian cancer |
HEY |
lysophosphatidic acid(LPA) |
modulate |
4.0 |
12181443 |
acc1141 |
AKT |
phosphorylation |
Thr308 |
human |
ovarian cancer |
HEY |
sphingosine-1-phosphate (S1P) |
modulate |
4.0 |
12181443 |
acc1142 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
HEY |
lysophosphatidic acid(LPA) |
modulate |
4.0 |
12181443 |
acc1143 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
HEY |
sphingosine-1-phosphate (S1P) |
modulate |
4.0 |
12181443 |
acc1144 |
AKT |
phosphorylation |
Thr308 |
human |
ovarian cancer |
HEY |
paclitaxel |
inhibit |
5.0 |
12181443 |
acc1145 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
HEY |
paclitaxel |
inhibit |
5.0 |
12181443 |
acc1146 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
XG-6 |
mAVE1642 |
no effect |
2.0 |
16951388 |
acc1147 |
EGFR |
phosphorylation |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
MCI-186 |
modulate |
4.0 |
15868956 |
acc1148 |
EGFR |
phosphorylation |
unclear |
human |
mesothelioma |
MSTO-211H |
MCI-186 |
modulate |
4.0 |
15868956 |
acc1149 |
EGFR |
phosphorylation |
unclear |
human |
gastric cancer |
TMK-1 |
MCI-186 |
modulate |
4.0 |
15868956 |
acc1150 |
EGFR |
phosphorylation |
unclear |
human |
breast carcinoma |
MCF7 |
MCI-186 |
modulate |
4.0 |
15868956 |
acc1151 |
BCL2 |
phosphorylation |
Ser70 |
human |
melanoma |
M-14 |
mebendazole |
promote |
5.0 |
18667591 |
acc1152 |
BCL2 |
phosphorylation |
Ser70 |
human |
melanoma |
SK-Mel-19 |
mebendazole |
promote |
5.0 |
18667591 |
acc1153 |
FOXO3a |
phosphorylation |
Ser253 |
mouse |
ovarian cancer |
|
melatonin + cisplatin |
modulate |
4.0 |
26882203 |
acc1154 |
PTEN |
phosphorylation |
Ser380 |
mouse |
ovarian cancer |
|
melatonin + cisplatin |
modulate |
4.0 |
26882203 |
acc1155 |
AKT |
phosphorylation |
Ser473 |
mouse |
ovarian cancer |
|
melatonin + cisplatin |
modulate |
4.0 |
26882203 |
acc1156 |
AKT |
phosphorylation |
Ser473 |
mouse |
colorectal cancer |
C57BL/6 mice |
metformin |
modulate |
4.0 |
20228137 |
acc1157 |
AMPK |
phosphorylation |
Thr183 |
mouse |
colorectal cancer |
C57BL/6 mice |
metformin |
modulate |
4.0 |
20228137 |
acc1158 |
AMPK |
phosphorylation |
Thr172 |
mouse |
colorectal cancer |
C57BL/6 mice |
metformin |
modulate |
4.0 |
20228137 |
acc1159 |
acetyl-CoA carboxylase |
phosphorylation |
Ser79 |
mouse |
colorectal cancer |
C57BL/6 mice |
metformin |
modulate |
4.0 |
20228137 |
acc1160 |
HER2 |
phosphorylation |
Tyr1248 |
human |
breast cancer |
MCF7 |
tamoxifen |
inhibit |
5.0 |
26581908 |
acc1161 |
HER3 |
phosphorylation |
Tyr1289 |
human |
breast cancer |
MCF7 |
tamoxifen |
inhibit |
5.0 |
26581908 |
acc1162 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
tamoxifen |
inhibit |
5.0 |
26581908 |
acc1163 |
AMPK |
phosphorylation |
Thr183 |
rat |
uterine leiomyomas |
ELT-3 |
metformin |
modulate |
4.0 |
22835064 |
acc1164 |
AMPK |
phosphorylation |
Thr172 |
rat |
uterine leiomyomas |
ELT-3 |
metformin |
modulate |
4.0 |
22835064 |
acc1165 |
S6 |
phosphorylation |
Ser235 |
rat |
uterine leiomyomas |
ELT-3 |
metformin |
modulate |
4.0 |
22835064 |
acc1166 |
S6 |
phosphorylation |
Ser236 |
rat |
uterine leiomyomas |
ELT-3 |
metformin |
modulate |
4.0 |
22835064 |
acc1167 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
BxPC-3 |
gemcitabine |
inhibit |
5.0 |
28602977 |
acc1168 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
T3M4 |
gemcitabine |
inhibit |
5.0 |
28602977 |
acc1169 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc1170 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc1171 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
doxorubicin |
inhibit |
5.0 |
32460059 |
acc1172 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
THP-1 |
doxorubicin |
inhibit |
5.0 |
32460059 |
acc1173 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML2 |
doxorubicin |
inhibit |
5.0 |
32460059 |
acc1174 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
doxorubicin |
inhibit |
5.0 |
32460059 |
acc1175 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
NCI-H460 |
docetaxel |
inhibit |
5.0 |
20571069 |
acc1176 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780 |
doxorubicin |
inhibit |
5.0 |
20571069 |
acc1177 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
NCI-H460 |
carboplatin |
inhibit |
5.0 |
20571069 |
acc1178 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780 |
gemcitabine |
inhibit |
5.0 |
20571069 |
acc1179 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SMMC-7721 |
NR027113 |
modulate |
4.0 |
30468465 |
acc1180 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
SK-HEP-1 |
NR027113 |
modulate |
4.0 |
30468465 |
acc1181 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
temozolomide(TMZ) |
inhibit |
5.0 |
21730979 |
acc1182 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
Cisplatin |
inhibit |
5.0 |
21730979 |
acc1183 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
camptothecin |
inhibit |
5.0 |
21730979 |
acc1184 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
doxorubicin |
inhibit |
5.0 |
21730979 |
acc1185 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
hydroxyurea |
inhibit |
5.0 |
21730979 |
acc1186 |
CHK1 |
phosphorylation |
Ser345 |
human |
breast cancer |
MCF7 |
ionising radiation |
inhibit |
4.5 |
21730979 |
acc1187 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
MKN-28 |
Nintedanib |
modulate |
4.0 |
36002676 |
acc1188 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
AGS |
Nintedanib |
modulate |
4.0 |
36002676 |
acc1189 |
STAT3 |
phosphorylation |
Ser727 |
human |
gastric cancer |
MKN-28 |
Nintedanib |
modulate |
4.0 |
36002676 |
acc1190 |
STAT3 |
phosphorylation |
Ser727 |
human |
gastric cancer |
AGS |
Nintedanib |
modulate |
4.0 |
36002676 |
acc1191 |
CREB |
phosphorylation |
Ser133 |
mouse |
hepatocellular carcinoma |
Hepa1-6 |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1192 |
Sp1 |
phosphorylation |
Thr739 |
mouse |
hepatocellular carcinoma |
Hepa1-6 |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1193 |
HNF4A |
phosphorylation |
Ser313 |
mouse |
hepatocellular carcinoma |
Hepa1-6 |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1194 |
c-Myc |
phosphorylation |
Ser62 |
mouse |
hepatocellular carcinoma |
Hepa1-6 |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1195 |
CREB |
phosphorylation |
Ser133 |
mouse |
hepatocellular carcinoma |
Hca-F |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1196 |
Sp1 |
phosphorylation |
Thr739 |
mouse |
hepatocellular carcinoma |
Hca-F |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1197 |
HNF4A |
phosphorylation |
Ser313 |
mouse |
hepatocellular carcinoma |
Hca-F |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1198 |
c-Myc |
phosphorylation |
Ser62 |
mouse |
hepatocellular carcinoma |
Hca-F |
Cav-1 |
modulate |
3.0 |
31209283 |
acc1199 |
Bax |
phosphorylation |
Ser184 |
human |
lung cancer |
A549 |
Ceramide |
modulate |
4.0 |
16679323 |
acc1200 |
Bax |
phosphorylation |
Ser184 |
human |
lung cancer |
A549 |
okadaic acid (OA) |
modulate |
4.0 |
16679323 |
acc1201 |
CDK2 |
phosphorylation |
Thr160 |
human |
colorectal cancer |
LoVo |
adapalene |
modulate |
4.0 |
26398439 |
acc1202 |
CDK2 |
phosphorylation |
Thr160 |
human |
colorectal cancer |
DLD-1 |
adapalene |
modulate |
4.0 |
26398439 |
acc1203 |
Rb |
phosphorylation |
Ser795 |
human |
colorectal cancer |
LoVo |
adapalene |
modulate |
4.0 |
26398439 |
acc1204 |
Rb |
phosphorylation |
Ser795 |
human |
colorectal cancer |
DLD-1 |
adapalene |
modulate |
4.0 |
26398439 |
acc1205 |
STAT1 |
phosphorylation |
Tyr701 |
human |
lung cancer |
A549 |
oleic acid |
modulate |
4.0 |
33957086 |
acc1206 |
STAT1 |
phosphorylation |
Tyr701 |
human |
lung cancer |
A549 |
OEA |
modulate |
4.0 |
33957086 |
acc1207 |
AKT |
phosphorylation |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
PM2.5 |
modulate |
3.0 |
28521450 |
acc1208 |
AKT |
phosphorylation |
unclear |
human |
hepatocellular carcinoma |
HuH-7 |
PM2.5 |
modulate |
3.0 |
28521450 |
acc1209 |
BCL2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
HeLa |
paclitaxel |
enhance |
5.0 |
18306930 |
acc1210 |
BCL2 |
phosphorylation |
Ser70 |
human |
gastric cancer |
SNU 638 |
paclitaxel |
enhance |
5.0 |
18306930 |
acc1211 |
BCL2 |
phosphorylation |
Ser70 |
human |
gastric cancer |
SNU 668 |
paclitaxel |
enhance |
5.0 |
18306930 |
acc1212 |
BCL2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
A2780 |
paclitaxel + ABT-199 |
modulate |
4.0 |
29953843 |
acc1213 |
BCL2 |
phosphorylation |
Ser70 |
human |
cervical cancer |
HeLa |
paclitaxel + ABT-199 |
modulate |
4.0 |
29953843 |
acc1214 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
H460 |
paclitaxel + ABT-199 |
modulate |
4.0 |
29953843 |
acc1215 |
BCL2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
A2780/DDP |
paclitaxel + ABT-199 |
modulate |
4.0 |
29953843 |
acc1216 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-468 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1217 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
4T1 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1218 |
S6K1 |
phosphorylation |
Thr389 |
human |
breast cancer |
MDA-MB-468 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1219 |
S6K1 |
phosphorylation |
Thr389 |
human |
breast cancer |
4T1 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1220 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
MDA-MB-468 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1221 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
4T1 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1222 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
MDA-MB-468 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1223 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
4T1 |
Eribulin + everolimus |
modulate |
4.0 |
31480338 |
acc1224 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
HL-60 |
paclitaxel |
modulate |
4.0 |
11160861 |
acc1225 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
NUGC-3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1226 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
44As3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1227 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
58As9 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1228 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
MKN-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1229 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
TMK-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1230 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
SH101-P |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1231 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
NUGC-3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1232 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
44As3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1233 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
SNU-601 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1234 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
58As9 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1235 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
MKN-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1236 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
TMK-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1237 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
SNU-601 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1238 |
p38 |
phosphorylation |
Tyr182 |
human |
gastric cancer |
SH101-P |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1239 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
58As9 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1240 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
MKN-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1241 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
TMK-1 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1242 |
c-Jun |
phosphorylation |
Ser63 |
human |
gastric cancer |
SH101-P |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1243 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
NUGC-3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1244 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
44As3 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1245 |
p38 |
phosphorylation |
Thr180 |
human |
gastric cancer |
SNU-601 |
Cisplatin |
modulate |
4.0 |
35922477 |
acc1246 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT29 |
paclitaxel |
enhance |
5.0 |
21594648 |
acc1247 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HCT15 |
paclitaxel |
enhance |
5.0 |
21594648 |
acc1248 |
Arix |
phosphorylation |
unclear |
human |
neuroblastoma |
SH-SY5Y |
UO126 |
modulate |
3.0 |
16156742 |
acc1249 |
Arix |
phosphorylation |
unclear |
human |
neuroblastoma |
SH-SY5Y |
PD98059 |
modulate |
3.0 |
16156742 |
acc1250 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SK-BR-3 |
pelitinib |
inhibit |
5.0 |
21046231 |
acc1251 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
T47D |
pelitinib |
inhibit |
5.0 |
21046231 |
acc1252 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
SK-BR-3 |
canertinib |
inhibit |
5.0 |
21046231 |
acc1253 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
T47D |
canertinib |
inhibit |
5.0 |
21046231 |
acc1254 |
beta-catenin |
phosphorylation |
Ser552 |
human |
colon cancer |
HCT116 |
Rp-8-Br-cAMPS |
modulate |
4.0 |
22168384 |
acc1255 |
beta-catenin |
phosphorylation |
Ser675 |
human |
colon cancer |
HCT116 |
Rp-8-Br-cAMPS |
modulate |
4.0 |
22168384 |
acc1256 |
c-Src |
phosphorylation |
Tyr416 |
human |
breast cancer |
MDA-MB-231 |
pHe |
modulate |
3.0 |
35538691 |
acc1257 |
c-Src |
phosphorylation |
Tyr416 |
human |
breast cancer |
LM3 |
pHe |
modulate |
3.0 |
35538691 |
acc1258 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
radiation |
inhibit |
4.5 |
11358816 |
acc1259 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
radiation |
inhibit |
4.5 |
11358816 |
acc1260 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1261 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1262 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1263 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1264 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1265 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1266 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1155 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1267 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
radiation |
inhibit |
4.5 |
11358816 |
acc1268 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
radiation |
inhibit |
4.5 |
11358816 |
acc1269 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1703 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1270 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1703 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1271 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1703 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1272 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1703 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1273 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1703 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1274 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1703 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1275 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1276 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1277 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1278 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1279 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H157 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1280 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1281 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1703 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1282 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1283 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1284 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1285 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H1155 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1286 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1703 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1287 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1703 |
trastuzumab |
inhibit |
5.0 |
11358816 |
acc1288 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1703 |
gemcitabine |
inhibit |
5.0 |
11358816 |
acc1289 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
etoposide |
inhibit |
5.0 |
11358816 |
acc1290 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
CDDP |
inhibit |
5.0 |
11358816 |
acc1291 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
paclitaxel |
inhibit |
5.0 |
11358816 |
acc1292 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
SW480 |
phytomedicine |
modulate |
4.0 |
25647359 |
acc1293 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
DLD-1 |
phytomedicine |
modulate |
4.0 |
25647359 |
acc1294 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
T24 |
gemcitabine |
inhibit |
5.0 |
33452459 |
acc1295 |
AKT |
phosphorylation |
Thr308 |
human |
bladder cancer |
T24 |
gemcitabine |
inhibit |
5.0 |
33452459 |
acc1296 |
AKT |
phosphorylation |
Ser473 |
human |
bladder cancer |
UM-UC-3 |
gemcitabine |
inhibit |
5.0 |
33452459 |
acc1297 |
AKT |
phosphorylation |
Thr308 |
human |
bladder cancer |
UM-UC-3 |
gemcitabine |
inhibit |
5.0 |
33452459 |
acc1298 |
ERK1 |
phosphorylation |
Thr202 |
human |
thyroid cancer |
LOXIMVI |
AMG655 |
increase |
5.0 |
25867065 |
acc1299 |
ERK1 |
phosphorylation |
Tyr204 |
human |
thyroid cancer |
LOXIMVI |
AMG655 |
increase |
5.0 |
25867065 |
acc1300 |
ERK2 |
phosphorylation |
Thr185 |
human |
thyroid cancer |
TPC-1 |
AMG655 |
increase |
5.0 |
25867065 |
acc1301 |
ERK2 |
phosphorylation |
Tyr187 |
human |
thyroid cancer |
TPC-1 |
AMG655 |
increase |
5.0 |
25867065 |
acc1302 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
LOXIMVI |
TRAIL |
increase |
5.0 |
25867065 |
acc1303 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
LOXIMVI |
TRAIL |
increase |
5.0 |
25867065 |
acc1304 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
LOXIMVI |
TRAIL |
increase |
5.0 |
25867065 |
acc1305 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
LOXIMVI |
TRAIL |
increase |
5.0 |
25867065 |
acc1306 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
A375 |
TRAIL |
increase |
5.0 |
25867065 |
acc1307 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
A375 |
TRAIL |
increase |
5.0 |
25867065 |
acc1308 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
A375 |
TRAIL |
increase |
5.0 |
25867065 |
acc1309 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
A375 |
TRAIL |
increase |
5.0 |
25867065 |
acc1310 |
ERK2 |
phosphorylation |
Thr185 |
human |
thyroid cancer |
LOXIMVI |
AMG655 |
increase |
5.0 |
25867065 |
acc1311 |
ERK2 |
phosphorylation |
Tyr187 |
human |
thyroid cancer |
LOXIMVI |
AMG655 |
increase |
5.0 |
25867065 |
acc1312 |
ERK1 |
phosphorylation |
Thr202 |
human |
thyroid cancer |
BCPAP |
AMG655 |
increase |
5.0 |
25867065 |
acc1313 |
ERK1 |
phosphorylation |
Tyr204 |
human |
thyroid cancer |
BCPAP |
AMG655 |
increase |
5.0 |
25867065 |
acc1314 |
ERK2 |
phosphorylation |
Thr185 |
human |
thyroid cancer |
BCPAP |
AMG655 |
increase |
5.0 |
25867065 |
acc1315 |
ERK2 |
phosphorylation |
Tyr187 |
human |
thyroid cancer |
BCPAP |
AMG655 |
increase |
5.0 |
25867065 |
acc1316 |
ERK1 |
phosphorylation |
Thr202 |
human |
thyroid cancer |
TPC-1 |
AMG655 |
increase |
5.0 |
25867065 |
acc1317 |
ERK1 |
phosphorylation |
Tyr204 |
human |
thyroid cancer |
TPC-1 |
AMG655 |
increase |
5.0 |
25867065 |
acc1318 |
Chk1 |
phosphorylation |
Ser280 |
human |
melanoma |
A375(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1319 |
Chk1 |
phosphorylation |
Ser280 |
human |
melanoma |
WM9(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1320 |
Chk1 |
phosphorylation |
Ser296 |
human |
melanoma |
A375(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1321 |
Chk1 |
phosphorylation |
Ser296 |
human |
melanoma |
WM9(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1322 |
Chk1 |
phosphorylation |
Ser317 |
human |
melanoma |
A375(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1323 |
Chk1 |
phosphorylation |
Ser317 |
human |
melanoma |
WM9(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1324 |
Chk1 |
phosphorylation |
Ser345 |
human |
melanoma |
A375(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1325 |
Chk1 |
phosphorylation |
Ser345 |
human |
melanoma |
WM9(PLX4032-res) |
PLX4032 + PF477736 |
modulate |
4.0 |
30100999 |
acc1326 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
SB01 |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc1327 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
SB01 |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc1328 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
SB01 |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc1329 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
SB01 |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc1330 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
rapamycin |
modulate |
4.0 |
22422409 |
acc1331 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-435 |
rapamycin |
modulate |
4.0 |
22422409 |
acc1332 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MDA-MB-231 |
rapamycin |
modulate |
4.0 |
22422409 |
acc1333 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MDA-MB-435 |
rapamycin |
modulate |
4.0 |
22422409 |
acc1334 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
OS2 |
rapamycin |
resist |
5.0 |
20486173 |
acc1335 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
OS9 |
rapamycin |
resist |
5.0 |
20486173 |
acc1336 |
AKT |
phosphorylation |
Ser473 |
human |
osteosarcoma |
OS17 |
rapamycin |
resist |
5.0 |
20486173 |
acc1337 |
eIF4E |
phosphorylation |
Ser209 |
human |
prostate cancer |
DU145 |
MNK-inh |
modulate |
4.0 |
18809972 |
acc1338 |
eIF4E |
phosphorylation |
Ser209 |
human |
prostate cancer |
PC3 |
rapamycin |
modulate |
4.0 |
18809972 |
acc1339 |
eIF4E |
phosphorylation |
Ser209 |
human |
prostate cancer |
LNCaP |
rapamycin |
modulate |
4.0 |
18809972 |
acc1340 |
mTOR |
phosphorylation |
Ser2448 |
human |
breast cancer |
MCF7 |
rapamycin |
modulate |
3.0 |
30154572 |
acc1341 |
claudin-7 |
phosphorylation |
Ser204 |
human |
lung cancer |
H522 |
Cisplatin |
enhance |
5.0 |
23433123 |
acc1342 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-468 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1343 |
mTOR |
phosphorylation |
Ser2481 |
human |
breast cancer |
MDA-MB-468 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1344 |
FOXO3A |
phosphorylation |
Thr32 |
human |
breast cancer |
MDA-MB-468 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1345 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1346 |
mTOR |
phosphorylation |
Ser2481 |
human |
breast cancer |
MDA-MB-231 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1347 |
FOXO3A |
phosphorylation |
Thr32 |
human |
breast cancer |
MDA-MB-231 |
IBP OV |
modulate |
3.0 |
24113176 |
acc1348 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
A549 |
resveratrol |
modulate |
4.0 |
31665911 |
acc1349 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
resveratrol |
modulate |
4.0 |
31665911 |
acc1350 |
GSK3beta |
phosphorylation |
Ser9 |
human |
lung cancer |
A549 |
resveratrol |
modulate |
4.0 |
31665911 |
acc1351 |
ATF-2 |
phosphorylation |
Thr71 |
mouse |
melanoma |
B16 |
Taxol |
inhibit |
5.0 |
18269766 |
acc1352 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
A2780/T |
Rg5 + docetaxel |
modulate |
4.0 |
32148406 |
acc1353 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1792 |
rosiglitazone |
modulate |
4.0 |
16505118 |
acc1354 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H1838 |
rosiglitazone |
modulate |
4.0 |
16505118 |
acc1355 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
PANC-1 |
Sinapic acid(SA) |
modulate |
4.0 |
34859906 |
acc1356 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
SW1990 |
Sinapic acid(SA) |
modulate |
4.0 |
34859906 |
acc1357 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
HCC1954 |
SAIT301 |
inhibit |
5.0 |
24662823 |
acc1358 |
AR |
phosphorylation |
Ser81 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1359 |
AMPK |
phosphorylation |
Thr172 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1360 |
AMPK |
phosphorylation |
Thr183 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1361 |
Raptor |
phosphorylation |
Ser792 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1362 |
TSC-2 |
phosphorylation |
Ser1387 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1363 |
TSC-2 |
phosphorylation |
Ser939 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1364 |
TSC-2 |
phosphorylation |
Thr1462 |
human |
prostate cancer |
C4-2 |
salinomycin |
modulate |
4.0 |
27557496 |
acc1365 |
p38MAPK |
phosphorylation |
Thr180 |
human |
glioblastoma |
T98G |
SB203581 |
inhibit |
5.0 |
37185746 |
acc1366 |
p38MAPK |
phosphorylation |
Tyr182 |
human |
glioblastoma |
T98G |
SB203581 |
inhibit |
5.0 |
37185746 |
acc1367 |
mTOR |
phosphorylation |
Ser2448 |
human |
prostate cancer |
DU145 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1368 |
mTOR |
phosphorylation |
Ser2448 |
human |
prostate cancer |
PC3 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1369 |
AKT2 |
phosphorylation |
Thr309 |
human |
prostate cancer |
LNCaP |
SB225003 |
modulate |
4.0 |
29917166 |
acc1370 |
AKT3 |
phosphorylation |
Thr305 |
human |
prostate cancer |
LNCaP |
SB225003 |
modulate |
4.0 |
29917166 |
acc1371 |
mTOR |
phosphorylation |
Ser2448 |
human |
prostate cancer |
LNCaP |
SB225003 |
modulate |
4.0 |
29917166 |
acc1372 |
AKT1 |
phosphorylation |
Thr308 |
human |
prostate cancer |
DU145 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1373 |
AKT2 |
phosphorylation |
Thr309 |
human |
prostate cancer |
DU145 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1374 |
AKT3 |
phosphorylation |
Thr305 |
human |
prostate cancer |
DU145 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1375 |
AKT1 |
phosphorylation |
Thr308 |
human |
prostate cancer |
PC3 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1376 |
AKT2 |
phosphorylation |
Thr309 |
human |
prostate cancer |
PC3 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1377 |
AKT3 |
phosphorylation |
Thr305 |
human |
prostate cancer |
PC3 |
SB225003 |
modulate |
4.0 |
29917166 |
acc1378 |
AKT1 |
phosphorylation |
Thr308 |
human |
prostate cancer |
LNCaP |
SB225003 |
modulate |
4.0 |
29917166 |
acc1379 |
AKT |
phosphorylation |
Ser473 |
human |
Sarcoma |
EW8 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1380 |
AKT |
phosphorylation |
Ser473 |
human |
Sarcoma |
JR1 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1381 |
IN-R |
phosphorylation |
Tyr1146 |
human |
Sarcoma |
Rh18 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1382 |
IN-R |
phosphorylation |
Tyr1146 |
human |
Sarcoma |
Rh30 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1383 |
AKT |
phosphorylation |
Ser473 |
human |
Sarcoma |
Rh18 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1384 |
AKT |
phosphorylation |
Ser473 |
human |
Sarcoma |
Rh30 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1385 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
Sarcoma |
EW8 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1386 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
Sarcoma |
JR1 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1387 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
Sarcoma |
Rh18 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1388 |
IGF-IR |
phosphorylation |
Tyr1131 |
human |
Sarcoma |
Rh30 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1389 |
IN-R |
phosphorylation |
Tyr1146 |
human |
Sarcoma |
EW8 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1390 |
IN-R |
phosphorylation |
Tyr1146 |
human |
Sarcoma |
JR1 |
SCH717454 |
modulate |
4.0 |
22188815 |
acc1391 |
BCL2 |
phosphorylation |
Ser70 |
human |
hepatocellular carcinoma |
Bel7404 |
oxaliplatin (OXA) |
inhibit |
5.0 |
23279642 |
acc1392 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
PC3 |
selenium |
modulate |
3.0 |
16505097 |
acc1393 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
selenium |
modulate |
3.0 |
16505097 |
acc1394 |
FoxO1 |
phosphorylation |
Ser218 |
human |
sarcoma |
ISO-HAS-B |
ATG(aPKC inhibitor) |
modulate |
4.0 |
30559384 |
acc1395 |
FoxO1 |
phosphorylation |
Ser218 |
human |
sarcoma |
AS-M |
ATM(aPKC inhibitor) |
modulate |
4.0 |
30559384 |
acc1396 |
FoxO1 |
phosphorylation |
Ser218 |
human |
sarcoma |
ISO-HAS-B |
ATM(aPKC inhibitor) |
modulate |
4.0 |
30559384 |
acc1397 |
FoxO1 |
phosphorylation |
Ser218 |
human |
sarcoma |
AS-M |
ATG(aPKC inhibitor) |
modulate |
4.0 |
30559384 |
acc1398 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
KG-1 |
KP372-1 |
modulate |
4.0 |
16585200 |
acc1399 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
U937 |
KP372-1 |
modulate |
4.0 |
16585200 |
acc1400 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
TF-1 |
KP372-1 |
modulate |
4.0 |
16585200 |
acc1401 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
NCI-H69 |
NNK |
modulate |
4.0 |
15210690 |
acc1402 |
c-Myc |
phosphorylation |
Thr58 |
human |
lung cancer |
NCI-H69 |
NNK |
modulate |
4.0 |
15210690 |
acc1403 |
c-Myc |
phosphorylation |
Thr58 |
human |
lung cancer |
NCI-H82 |
staurosporine |
modulate |
4.0 |
15210690 |
acc1404 |
c-Myc |
phosphorylation |
Ser62 |
human |
lung cancer |
NCI-H82 |
staurosporine |
modulate |
4.0 |
15210690 |
acc1405 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
NCI-H82 |
staurosporine |
modulate |
4.0 |
15210690 |
acc1406 |
c-Myc |
phosphorylation |
Ser62 |
human |
lung cancer |
NCI-H69 |
NNK |
modulate |
4.0 |
15210690 |
acc1407 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
NCI-H82 |
NNK |
modulate |
4.0 |
15210690 |
acc1408 |
c-Myc |
phosphorylation |
Thr58 |
human |
lung cancer |
NCI-H82 |
NNK |
modulate |
4.0 |
15210690 |
acc1409 |
c-Myc |
phosphorylation |
Ser62 |
human |
lung cancer |
NCI-H82 |
NNK |
modulate |
4.0 |
15210690 |
acc1410 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
NCI-H82 |
Cisplatin |
suppress |
5.0 |
15210690 |
acc1411 |
c-Myc |
phosphorylation |
Thr58 |
human |
lung cancer |
NCI-H82 |
PD98059 |
modulate |
4.0 |
15210690 |
acc1412 |
c-Myc |
phosphorylation |
Ser62 |
human |
lung cancer |
NCI-H82 |
PD98059 |
modulate |
4.0 |
15210690 |
acc1413 |
BCL2 |
phosphorylation |
Ser70 |
human |
lung cancer |
NCI-H82 |
PD98059 |
modulate |
4.0 |
15210690 |
acc1414 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H2286 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1415 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H2286 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1416 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H2286 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1417 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
HCC366 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1418 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H2286 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1419 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H2286 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1420 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
HCC366 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1421 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
HCC366 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1422 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
HCC366 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1423 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
HCC366 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1424 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H2286 |
dasatinib + crizotinib |
modulate |
4.0 |
25348954 |
acc1425 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
HCC366 |
dasatinib + BMS-754807 |
modulate |
4.0 |
25348954 |
acc1426 |
HSP27 |
phosphorylation |
Ser82 |
human |
lung cancer |
A549 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1427 |
eIF2a |
phosphorylation |
Ser51 |
human |
lung cancer |
A549 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1428 |
IRS1 |
phosphorylation |
Ser1101 |
human |
lung cancer |
A549 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1429 |
HSP27 |
phosphorylation |
Ser82 |
human |
lung cancer |
H1299 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1430 |
eIF2a |
phosphorylation |
Ser51 |
human |
lung cancer |
H1299 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1431 |
IRS1 |
phosphorylation |
Ser1101 |
human |
lung cancer |
H1299 |
ZNF323A OV |
modulate |
3.0 |
32576196 |
acc1432 |
AKT |
phosphorylation |
Ser473 |
mouse |
leukemia |
DA1-3b/M1 |
GILZ ov |
inhibit |
4.5 |
21804606 |
acc1433 |
AKT |
phosphorylation |
Ser473 |
mouse |
leukemia |
DA1-3b/M1 |
imatinib |
inhibit |
5.0 |
21804606 |
acc1434 |
AKT |
phosphorylation |
Ser473 |
mouse |
leukemia |
DA1-3b/M2 |
imatinib |
inhibit |
5.0 |
21804606 |
acc1435 |
AKT |
phosphorylation |
Ser473 |
mouse |
leukemia |
DA1-3b/M2 |
dasatinib |
inhibit |
5.0 |
21804606 |
acc1436 |
AKT |
phosphorylation |
Ser473 |
human |
leukemia |
K562-r |
GILZ ov |
inhibit |
4.5 |
21804606 |
acc1437 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
|
rapamycin |
modulate |
4.0 |
23874880 |
acc1438 |
p70S6K |
phosphorylation |
Ser371 |
human |
lung cancer |
|
Ku0063794 |
increase |
5.0 |
23874880 |
acc1439 |
mTOR |
phosphorylation |
Ser2448 |
rat |
glioma |
C6 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1440 |
AKT |
phosphorylation |
Ser473 |
rat |
glioma |
C6 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1441 |
ULK1 |
phosphorylation |
Ser467 |
rat |
glioma |
C6 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1442 |
mTOR |
phosphorylation |
Ser2448 |
human |
glioma |
U251 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1443 |
AKT |
phosphorylation |
Ser473 |
human |
glioma |
U251 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1444 |
ULK1 |
phosphorylation |
Ser467 |
human |
glioma |
U251 |
xanthatin |
modulate |
4.0 |
36572650 |
acc1445 |
p38 |
phosphorylation |
Tyr182 |
human |
hepatocellular carcinoma |
SMMC-7721 |
mAb AA98 |
modulate |
4.0 |
17121934 |
acc1446 |
p53 |
phosphorylation |
Ser15 |
human |
melanoma |
A375 |
"3,3'-diselenodipropionic acid (DSeA)" |
modulate |
4.0 |
25277183 |
acc1447 |
p53 |
phosphorylation |
Ser15 |
human |
melanoma |
A375 |
TRAIL |
inhibit |
5.0 |
25277183 |
acc1448 |
Akt |
phosphorylation |
Thr308 |
human |
melanoma |
A375 |
"3,3'-diselenodipropionic acid (DSeA)" |
modulate |
4.0 |
25277183 |
acc1449 |
Akt |
phosphorylation |
Thr308 |
human |
melanoma |
A375 |
TRAIL |
inhibit |
5.0 |
25277183 |
acc1450 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1451 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
MCF7 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1452 |
S6 |
phosphorylation |
Ser235 |
human |
colon cancer |
COLO205 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1453 |
S6 |
phosphorylation |
Ser236 |
human |
colon cancer |
COLO205 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1454 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1455 |
S6 |
phosphorylation |
Ser235 |
human |
lung cancer |
A549 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1456 |
S6 |
phosphorylation |
Ser236 |
human |
lung cancer |
A549 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1457 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
SW620 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1458 |
S6 |
phosphorylation |
Ser235 |
human |
colorectal cancer |
SW620 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1459 |
S6 |
phosphorylation |
Ser236 |
human |
colorectal cancer |
SW620 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1460 |
AKT |
phosphorylation |
Ser473 |
human |
glioma |
U87-MG |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1461 |
S6 |
phosphorylation |
Ser235 |
human |
glioma |
U87-MG |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1462 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
MCF7 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1463 |
S6 |
phosphorylation |
Ser236 |
human |
glioma |
U87-MG |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1464 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-468 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1465 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
MDA-MB-468 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1466 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
MDA-MB-468 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1467 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
BT474 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1468 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
BT474 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1469 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
BT474 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1470 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
COLO205 |
SHR8443 |
modulate |
4.0 |
29296217 |
acc1471 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1472 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1473 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1474 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1475 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1476 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1477 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1478 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1479 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1480 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1481 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1482 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1483 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1484 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1485 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1486 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1487 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1488 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1489 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1490 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1491 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1492 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1493 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1494 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1495 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1496 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1497 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1498 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1499 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1500 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1501 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1502 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 + axitinib |
modulate |
4.0 |
21390185 |
acc1503 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1504 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
SN-38 |
modulate |
4.0 |
21390185 |
acc1505 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
Capan-1 |
axitinib |
modulate |
4.0 |
21390185 |
acc1506 |
AKT |
phosphorylation |
Thr308 |
human |
pancreas cancer |
MIA PaCa-2 |
axitinib |
modulate |
4.0 |
21390185 |
acc1507 |
erbB3 |
phosphorylation |
unclear |
human |
breast cancer |
MDA-MB-453 |
SNDX-275 + trastuzumab |
modulate |
4.0 |
21497990 |
acc1508 |
erbB3 |
phosphorylation |
unclear |
human |
breast cancer |
BT474 |
SNDX-275 + trastuzumab |
modulate |
4.0 |
21497990 |
acc1509 |
AKT |
phosphorylation |
unclear |
mouse |
hepatocellular carcinoma |
NK92-MI |
sorafenib |
modulate |
4.0 |
23409093 |
acc1510 |
ERK |
phosphorylation |
unclear |
human |
bladder cancer |
T24 |
sorafenib |
modulate |
4.0 |
20649572 |
acc1511 |
ERK |
phosphorylation |
unclear |
human |
bladder cancer |
J82 |
sorafenib |
modulate |
4.0 |
20649572 |
acc1512 |
ERK |
phosphorylation |
unclear |
human |
bladder cancer |
RT4 |
sorafenib |
modulate |
4.0 |
20649572 |
acc1513 |
FKHR |
phosphorylation |
Ser256 |
human |
lung cancer |
GLC-82 |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1514 |
FKHRL1 |
phosphorylation |
Ser318 |
human |
lung cancer |
GLC-82 |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1515 |
FKHRL1 |
phosphorylation |
Ser321 |
human |
lung cancer |
GLC-82 |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1516 |
FKHR |
phosphorylation |
Ser256 |
human |
hepatocellular carcinoma |
Hep3B |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1517 |
FKHRL1 |
phosphorylation |
Ser318 |
human |
hepatocellular carcinoma |
Hep3B |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1518 |
FKHRL1 |
phosphorylation |
Ser321 |
human |
hepatocellular carcinoma |
Hep3B |
SYUNZ-16 |
modulate |
4.0 |
19904742 |
acc1519 |
bcl-2 |
phosphorylation |
Ser70 |
human |
breast cancer |
MCF-18 |
docetaxel |
modulate |
4.0 |
12576925 |
acc1520 |
BCL2 |
phosphorylation |
Ser70 |
human |
prostate cancer |
|
Taxol |
modulate |
4.0 |
8640809 |
acc1521 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
MKN45 |
HP590 |
modulate |
4.0 |
36103247 |
acc1522 |
STAT3 |
phosphorylation |
Ser727 |
human |
gastric cancer |
MKN45 |
HP590 |
modulate |
4.0 |
36103247 |
acc1523 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
AGS |
HP590 |
modulate |
4.0 |
36103247 |
acc1524 |
STAT3 |
phosphorylation |
Ser727 |
human |
gastric cancer |
AGS |
HP590 |
modulate |
4.0 |
36103247 |
acc1525 |
STAT3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
MGC803 |
HP590 |
modulate |
4.0 |
36103247 |
acc1526 |
STAT3 |
phosphorylation |
Ser727 |
human |
gastric cancer |
MGC803 |
HP590 |
modulate |
4.0 |
36103247 |
acc1527 |
USP8 |
phosphorylation |
Thr907 |
human |
breast cancer |
MCF7 |
NRG1 OV |
modulate |
3.0 |
17210635 |
acc1528 |
ErbB3 |
ubiquitination |
unclear |
human |
breast cancer |
MCF7 |
NRG1 OV |
modulate |
3.0 |
17210635 |
acc1529 |
ASK-1 |
phosphorylation |
Thr845 |
human |
glioma |
U87 |
temozolomide(TMZ) |
increase |
5.0 |
36951032 |
acc1530 |
ASK-1 |
phosphorylation |
Thr845 |
human |
glioma |
U251 |
temozolomide(TMZ) |
increase |
5.0 |
36951032 |
acc1531 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
BT474 |
anti-HER2 phage-based vaccine |
modulate |
4.0 |
36011047 |
acc1532 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
BT474 |
anti-HER2 phage-based vaccine |
modulate |
4.0 |
36011047 |
acc1533 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
BT474 |
anti-HER2 phage-based vaccine |
modulate |
4.0 |
36011047 |
acc1534 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
BT474 |
anti-HER2 phage-based vaccine |
modulate |
4.0 |
36011047 |
acc1535 |
HSP27 |
phosphorylation |
Ser15 |
human |
breast cancer |
JIMT-1 |
TZMB |
inhibit |
5.0 |
32545363 |
acc1536 |
HSP27 |
phosphorylation |
Ser78 |
human |
breast cancer |
JIMT-1 |
TZMB |
inhibit |
5.0 |
32545363 |
acc1537 |
PDGFRB |
phosphorylation |
Tyr751 |
human |
glioblastoma |
A172 |
EGCG |
modulate |
4.0 |
10198059 |
acc1538 |
PDGFRB |
phosphorylation |
Tyr751 |
mouse |
glioblastoma |
NIH 3T3 |
EGCG |
modulate |
4.0 |
10198059 |
acc1539 |
cdc25c |
phosphorylation |
Ser216 |
human |
lung cancer |
A549 |
LBH589 |
modulate |
4.0 |
21179472 |
acc1540 |
cdc2 |
phosphorylation |
Tyr15 |
human |
lung cancer |
A549 |
LBH589 |
modulate |
4.0 |
21179472 |
acc1541 |
cdc25c |
phosphorylation |
Ser216 |
human |
lung cancer |
A549 |
scriptaid |
modulate |
4.0 |
21179472 |
acc1542 |
cdc2 |
phosphorylation |
Tyr15 |
human |
lung cancer |
A549 |
scriptaid |
modulate |
4.0 |
21179472 |
acc1543 |
cdc25c |
phosphorylation |
Ser216 |
human |
lung cancer |
PC9 |
LBH589 |
modulate |
4.0 |
21179472 |
acc1544 |
cdc2 |
phosphorylation |
Tyr15 |
human |
lung cancer |
PC9 |
LBH589 |
modulate |
4.0 |
21179472 |
acc1545 |
cdc25c |
phosphorylation |
Ser216 |
human |
lung cancer |
PC9 |
scriptaid |
modulate |
4.0 |
21179472 |
acc1546 |
cdc2 |
phosphorylation |
Tyr15 |
human |
lung cancer |
PC9 |
scriptaid |
modulate |
4.0 |
21179472 |
acc1547 |
ERK1 |
phosphorylation |
Thr202 |
human |
sarcoma |
SA-4 |
vemurafenib |
modulate |
4.0 |
29570692 |
acc1548 |
ERK1 |
phosphorylation |
Tyr204 |
human |
sarcoma |
SA-4 |
vemurafenib |
modulate |
4.0 |
29570692 |
acc1549 |
ERK2 |
phosphorylation |
Thr185 |
human |
sarcoma |
SA-4 |
vemurafenib |
modulate |
4.0 |
29570692 |
acc1550 |
ERK2 |
phosphorylation |
Tyr187 |
human |
sarcoma |
SA-4 |
vemurafenib |
modulate |
4.0 |
29570692 |
acc1551 |
EGFR |
phosphorylation |
unclear |
human |
ovarian cancer |
SK-OV-3 |
Y-142 |
modulate |
4.0 |
23251664 |
acc1552 |
ERBB4 |
phosphorylation |
unclear |
human |
ovarian cancer |
SK-OV-3 |
Y-142 |
modulate |
4.0 |
23251664 |
acc1553 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
myeloma |
MOPC-31C |
YM529 + ONO-5920 |
modulate |
4.0 |
17979996 |
acc1554 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
myeloma |
MOPC-31C |
YM529 + ONO-5920 |
modulate |
4.0 |
17979996 |
acc1555 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
myeloma |
MOPC-31C |
YM529 + ONO-5920 |
modulate |
4.0 |
17979996 |
acc1556 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
myeloma |
MOPC-31C |
YM529 + ONO-5920 |
modulate |
4.0 |
17979996 |
acc1557 |
AKT |
phosphorylation |
Ser473 |
mouse |
myeloma |
MOPC-31C |
YM529 + ONO-5920 |
modulate |
4.0 |
17979996 |
acc1558 |
STAT3 |
phosphorylation |
Tyr705 |
human |
esophageal cancer |
ESO26-PAC-r (paclitaxel-resistant) |
paclitaxel |
inhibit |
5.0 |
32579788 |
acc1559 |
70S6K |
phosphorylation |
Thr389 |
human |
esophageal cancer |
ESO26-PAC-r (paclitaxel-resistant) |
paclitaxel |
inhibit |
5.0 |
32579788 |
acc1560 |
STAT3 |
phosphorylation |
Tyr705 |
human |
esophageal cancer |
KYAE-1-PAC-r(paclitaxel-resistant) |
paclitaxel |
inhibit |
5.0 |
32579788 |
acc1561 |
70S6K |
phosphorylation |
Thr389 |
human |
esophageal cancer |
KYAE-1-PAC-r(paclitaxel-resistant) |
paclitaxel |
inhibit |
5.0 |
32579788 |
acc1562 |
AKT |
phosphorylation |
Thr308 |
human |
Merkel cell carcinoma |
MGH-mcc1 |
ZST474 |
modulate |
4.0 |
22261808 |
acc1563 |
AKT |
phosphorylation |
Ser473 |
human |
Merkel cell carcinoma |
MGH-mcc1 |
ZST474 |
modulate |
4.0 |
22261808 |
acc1564 |
AKT |
phosphorylation |
Thr308 |
human |
Merkel cell carcinoma |
MGH-mcc1 |
NVP-BEZ235 |
modulate |
4.0 |
22261808 |
acc1565 |
AKT |
phosphorylation |
Ser473 |
human |
Merkel cell carcinoma |
MGH-mcc1 |
NVP-BEZ235 |
modulate |
4.0 |
22261808 |
acc1566 |
cullin |
neddylation |
unclear |
human |
breast cancer |
MCF7 |
MLN4924 |
modulate |
4.0 |
23151137 |
acc1567 |
cullin |
neddylation |
unclear |
human |
cervical cancer |
EGFP-LC3+ HeLa |
MLN4924 |
modulate |
4.0 |
23151137 |
acc1568 |
Stat3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1569 |
Stat3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-435 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1570 |
Jak2 |
phosphorylation |
Tyr1007 |
human |
breast cancer |
MDA-MB-231 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1571 |
Jak2 |
phosphorylation |
Tyr1007 |
human |
breast cancer |
MDA-MB-435 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1572 |
Jak2 |
phosphorylation |
Tyr1008 |
human |
breast cancer |
MDA-MB-231 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1573 |
Jak2 |
phosphorylation |
Tyr1008 |
human |
breast cancer |
MDA-MB-435 |
paclitaxel |
decrease |
5.0 |
21518725 |
acc1574 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
CN-CPT |
modulate |
4.0 |
27301177 |
acc1575 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
PC3 |
CN-CPT |
modulate |
4.0 |
27301177 |
acc1576 |
STAT3 |
phosphorylation |
Tyr705 |
human |
myeloma |
U266 |
LLL12 |
modulate |
4.0 |
21520044 |
acc1577 |
AKT |
phosphorylation |
Ser473 |
human |
esophageal cancer |
|
Cisplatin |
inhibit |
5.0 |
36525138 |
acc1578 |
YB-1 |
phosphorylation |
Ser102 |
human |
hepatocellular carcinoma |
HuH-7R(sorafenib-resistant) |
sorafenib |
modulate |
4.0 |
33379356 |
acc1579 |
AMPK |
phosphorylation |
Thr172 |
human |
leukemia |
|
acadesine |
modulate |
4.0 |
12522004 |
acc1580 |
AMPK |
phosphorylation |
Thr183 |
human |
leukemia |
|
acadesine |
modulate |
4.0 |
12522004 |
acc1581 |
ERalpha |
phosphorylation |
Ser118 |
human |
breast cancer |
MCF7 |
PGE2 |
modulate |
4.0 |
20093341 |
acc1582 |
ERalpha |
phosphorylation |
Ser167 |
human |
breast cancer |
MCF7 |
PGE2 |
modulate |
4.0 |
20093341 |
acc1583 |
ERalpha |
phosphorylation |
Ser305 |
human |
breast cancer |
MCF7 |
PGE2 |
modulate |
4.0 |
20093341 |
acc1584 |
CREB |
phosphorylation |
Ser133 |
human |
breast cancer |
MCF7 |
Radiotherapy |
modulate |
4.0 |
26655813 |
acc1585 |
Caveolin-1 |
phosphorylation |
Tyr14 |
human |
gastric cancer |
SGC7901/Adr |
adriamycin(Dox) |
resist |
5.0 |
25788263 |
acc1586 |
Caveolin-1 |
phosphorylation |
Tyr14 |
human |
breast cancer |
MCF7/Adr |
adriamycin(Dox) |
resist |
5.0 |
25788263 |
acc1587 |
Akt |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF7 |
tamoxifen |
resist |
5.0 |
21170675 |
acc1588 |
Akt |
phosphorylation |
Ser473 |
human |
breast cancer |
TAMR-MCF-7 |
5-Aza |
modulate |
4.0 |
21170675 |
acc1589 |
CIC |
phosphorylation |
Tyr1455 |
mouse |
glioma |
GL261 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1590 |
CIC |
phosphorylation |
Tyr1455 |
human |
glioma |
U87 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1591 |
CIC |
phosphorylation |
Tyr1455 |
human |
glioma |
GSC-7-2 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1592 |
c-Src |
phosphorylation |
Tyr416 |
mouse |
glioma |
GL261 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1593 |
c-Src |
phosphorylation |
Tyr416 |
human |
glioma |
U87 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1594 |
c-Src |
phosphorylation |
Tyr416 |
human |
glioma |
GSC-7-2 |
dasatinib |
modulate |
4.0 |
32029440 |
acc1595 |
CDK-2 |
phosphorylation |
unclear |
human |
breast cancer |
MDA-MB-435 |
mevalonate |
modulate |
4.0 |
15155733 |
acc1596 |
p90RSK2 |
phosphorylation |
Thr359 |
human |
lung cancer |
H226B |
Kazinol-E |
modulate |
4.0 |
26774343 |
acc1597 |
p90RSK2 |
phosphorylation |
Ser363 |
human |
lung cancer |
H226B |
Kazinol-E |
modulate |
4.0 |
26774343 |
acc1598 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
HBL-1 |
ibrutinib (PCI-32765) |
modulate |
4.0 |
33827598 |
acc1599 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
OCI-Ly10 |
ibrutinib (PCI-32765) |
modulate |
4.0 |
33827598 |
acc1600 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
HBL-1 |
acalabrutinib (ACP-196) |
modulate |
4.0 |
33827598 |
acc1601 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
OCI-Ly10 |
acalabrutinib (ACP-196) |
modulate |
4.0 |
33827598 |
acc1602 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
HBL-1 |
rituximab |
suppress |
5.0 |
33827598 |
acc1603 |
CYLD |
phosphorylation |
Ser418 |
human |
lymphoma |
OCI-Ly10 |
rituximab |
suppress |
5.0 |
33827598 |
acc1604 |
DDR1 |
phosphorylation |
Tyr792 |
human |
colon cancer |
HCT116 |
dapagliflozin |
modulate |
4.0 |
31979355 |
acc1605 |
ERK1 |
phosphorylation |
Tyr204 |
human |
bladder cancer |
UM-UC-6 |
dacomitinib |
modulate |
4.0 |
24166682 |
acc1606 |
ERK1 |
phosphorylation |
Thr202 |
human |
bladder cancer |
UM-UC-6 |
dacomitinib |
modulate |
4.0 |
24166682 |
acc1607 |
EGFR |
phosphorylation |
Tyr1068 |
human |
bladder cancer |
UM-UC-6 |
dacomitinib |
modulate |
4.0 |
24166682 |
acc1608 |
EGFR |
phosphorylation |
Tyr1068 |
human |
bladder cancer |
UM-UC-9 |
dacomitinib |
modulate |
4.0 |
24166682 |
acc1609 |
EGFR |
phosphorylation |
Tyr1068 |
human |
bladder cancer |
UM-UC-9 |
dacomitinib |
modulate |
4.0 |
24166682 |
acc1610 |
STAT3 |
phosphorylation |
Tyr705 |
human |
mucoepidermoid carcinoma |
UM-HMC-1 |
tocilizumab |
modulate |
4.0 |
26287605 |
acc1611 |
STAT3 |
phosphorylation |
Tyr705 |
human |
mucoepidermoid carcinoma |
UM-HMC-3A |
tocilizumab |
modulate |
4.0 |
26287605 |
acc1612 |
STAT3 |
phosphorylation |
Tyr705 |
human |
mucoepidermoid carcinoma |
UM-HMC-3B |
tocilizumab |
modulate |
4.0 |
26287605 |
acc1613 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HCT116 |
Auranofin + ICG-001 |
modulate |
4.0 |
34900688 |
acc1614 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
SW480 |
Auranofin + ICG-001 |
modulate |
4.0 |
34900688 |
acc1615 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
DLD-1 |
Auranofin + ICG-001 |
modulate |
4.0 |
34900688 |
acc1616 |
EGFR |
phosphorylation |
Tyr1173 |
human |
lung cancer |
HCC827 |
erlotinib |
modulate |
4.0 |
27612423 |
acc1617 |
EGFR |
phosphorylation |
Tyr1173 |
human |
lung cancer |
NCI-H3255 |
erlotinib |
modulate |
4.0 |
27612423 |
acc1618 |
EGFR |
phosphorylation |
Tyr1173 |
human |
lung cancer |
NCI-H1975 |
erlotinib |
modulate |
4.0 |
27612423 |
acc1619 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
|
erlotinib |
activate |
5.0 |
26247735 |
acc1620 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
CL1-5 |
curcumin |
modulate |
4.0 |
21858220 |
acc1621 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
A549 |
curcumin |
modulate |
4.0 |
21858220 |
acc1622 |
EGFR |
ubiquitination |
unclear |
human |
lung cancer |
A549 |
gefitinib |
promote |
5.0 |
21858220 |
acc1623 |
EGFR |
ubiquitination |
unclear |
human |
lung cancer |
H1975 |
gefitinib |
promote |
5.0 |
21858220 |
acc1624 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
H1975 |
curcumin |
modulate |
4.0 |
21858220 |
acc1625 |
EGFR |
ubiquitination |
unclear |
human |
lung cancer |
CL1-5 |
curcumin |
modulate |
4.0 |
21858220 |
acc1626 |
EGFR |
ubiquitination |
unclear |
human |
lung cancer |
A549 |
curcumin |
modulate |
4.0 |
21858220 |
acc1627 |
EGFR |
ubiquitination |
unclear |
human |
lung cancer |
H1975 |
curcumin |
modulate |
4.0 |
21858220 |
acc1628 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
CL1-5 |
gefitinib |
inhibit |
5.0 |
21858220 |
acc1629 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
A549 |
gefitinib |
inhibit |
5.0 |
21858220 |
acc1630 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
H1975 |
gefitinib |
inhibit |
5.0 |
21858220 |
acc1631 |
EGFR |
ubiquitination |
Tyr1068 |
human |
lung cancer |
CL1-5 |
gefitinib |
promote |
5.0 |
21858220 |
acc1632 |
EGFR |
phosphorylation |
Tyr1068 |
human |
lung cancer |
PC9 |
docetaxel + gefitinib |
modulate |
4.0 |
24682085 |
acc1633 |
EGFR |
phosphorylation |
Tyr1068 |
human |
head and neck cancer |
|
lysophosphatidic acid (LPA) |
modulate |
4.0 |
12414665 |
acc1634 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
SK-OV-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1635 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
SK-BR-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1636 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
SK-OV-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1637 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
SK-BR-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1638 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
SK-OV-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1639 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
SK-BR-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1640 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
SK-OV-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1641 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
SK-BR-3 |
DpdtC |
modulate |
4.0 |
29467385 |
acc1642 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
H1666 |
gefitinib |
decrease |
5.0 |
22777356 |
acc1643 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
H1666 |
gefitinib |
decrease |
5.0 |
22777356 |
acc1644 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
H1666 |
gefitinib |
decrease |
5.0 |
22777356 |
acc1645 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
H1666 |
gefitinib |
decrease |
5.0 |
22777356 |
acc1646 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
PC9GR |
gefitinib |
inhibit |
5.0 |
31671073 |
acc1647 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
PC9GR |
osimertinib |
inhibit |
5.0 |
31671073 |
acc1648 |
EGFR |
phosphorylation |
Tyr1068 |
human |
pancreas cancer |
L3.6pl |
gefitinib |
modulate |
4.0 |
16585207 |
acc1649 |
AKT |
phosphorylation |
Ser473 |
human |
pancreas cancer |
L3.6pl |
gefitinib |
modulate |
4.0 |
16585207 |
acc1650 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
lung cancer |
A549 |
doxorubicin |
negative |
5.0 |
31848319 |
acc1651 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
prostate cancer |
DU145 |
boric acid(BA) |
modulate |
4.0 |
30196486 |
acc1652 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
T47D |
lapatinib |
resist |
5.0 |
32365111 |
acc1653 |
eIF4E |
phosphorylation |
Ser209 |
human |
thyroid cancer |
FTC-133 |
rifabutin |
modulate |
4.0 |
28864377 |
acc1654 |
eIF4E |
phosphorylation |
Ser209 |
human |
thyroid cancer |
8505C |
rifabutin |
modulate |
4.0 |
28864377 |
acc1655 |
eIF4E |
phosphorylation |
Ser209 |
human |
thyroid cancer |
FTC-133 |
paclitaxel |
inhibit |
5.0 |
28864377 |
acc1656 |
eIF4E |
phosphorylation |
Ser209 |
human |
thyroid cancer |
8505C |
paclitaxel |
inhibit |
5.0 |
28864377 |
acc1657 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H3255 |
rifabutin |
modulate |
4.0 |
26944016 |
acc1658 |
beta-catenin |
phosphorylation |
Ser552 |
human |
lung cancer |
H3255 |
rifabutin |
modulate |
4.0 |
26944016 |
acc1659 |
eIF4E |
phosphorylation |
Ser209 |
human |
pancreas cancer |
PC-346C |
RAD001 |
inhibit |
5.0 |
28745319 |
acc1660 |
eIF4E |
phosphorylation |
Ser209 |
human |
pancreas cancer |
C4-2 |
RAD001 |
inhibit |
5.0 |
28745319 |
acc1661 |
eIF4E |
phosphorylation |
Ser209 |
human |
glioma |
U373 |
temozolomide(TMZ) |
resist |
5.0 |
27289018 |
acc1662 |
eIF4E |
phosphorylation |
Ser209 |
human |
glioma |
LN229 |
temozolomide(TMZ) |
resist |
5.0 |
27289018 |
acc1663 |
endoglin |
phosphorylation |
Thr |
human |
prostate cancer |
PC3-M |
TGF-beta1 |
modulate |
4.0 |
19736306 |
acc1664 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1665 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
Hep3B |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1666 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
HuH6 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1667 |
EGFR |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
PLC/PRF5 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1668 |
HER-3 |
phosphorylation |
Tyr1289 |
human |
hepatocellular carcinoma |
HepG2 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1669 |
HER-3 |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
Hep3B |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1670 |
HER-3 |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
HuH6 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1671 |
HER-3 |
phosphorylation |
Tyr1068 |
human |
hepatocellular carcinoma |
PLC/PRF5 |
sorafenib |
inhibit |
5.0 |
22414764 |
acc1672 |
EGFR |
phosphorylation |
unclear |
human |
thyroid cancer |
|
apigenin |
modulate |
4.0 |
11299771 |
acc1673 |
ERK |
phosphorylation |
unclear |
human |
thyroid cancer |
|
apigenin |
modulate |
4.0 |
11299771 |
acc1674 |
Rb |
phosphorylation |
unclear |
human |
breast cancer |
MCF7 |
apigenin |
modulate |
4.0 |
11299771 |
acc1675 |
ERK |
phosphorylation |
unclear |
human |
breast cancer |
MDA-MB-468 |
apigenin |
modulate |
4.0 |
11299771 |
acc1676 |
ERalpha |
phosphorylation |
Ser118 |
human |
breast cancer |
MCF7 |
LY294002 |
resist |
5.0 |
18941890 |
acc1677 |
ERalpha |
phosphorylation |
Ser167 |
human |
breast cancer |
MCF7 |
LY294002 |
resist |
5.0 |
18941890 |
acc1678 |
ERalpha |
phosphorylation |
Ser118 |
human |
breast cancer |
MCF7 |
ICI182780 |
resist |
5.0 |
18941890 |
acc1679 |
ERalpha |
phosphorylation |
Ser167 |
human |
breast cancer |
MCF7 |
ICI182780 |
resist |
5.0 |
18941890 |
acc1680 |
ERalpha |
phosphorylation |
Ser118 |
rat |
prolactinoma |
MMQ/BRO |
bromocriptine |
inhibit |
5.0 |
33173437 |
acc1681 |
ERalpha |
phosphorylation |
Ser118 |
human |
prolactinoma |
|
bromocriptine |
inhibit |
5.0 |
33173437 |
acc1682 |
ERG |
phosphorylation |
Ser96 |
human |
prostate cancer |
HEK293T |
TAK-242 |
modulate |
4.0 |
33554122 |
acc1683 |
ERK1 |
phosphorylation |
Thr202 |
human |
glioma |
C6 |
temozolomide(TMZ) |
modulate |
4.0 |
27878252 |
acc1684 |
ERK1 |
phosphorylation |
Tyr204 |
human |
glioma |
C6 |
temozolomide(TMZ) |
modulate |
4.0 |
27878252 |
acc1685 |
ERK2 |
phosphorylation |
Thr185 |
human |
glioma |
C6 |
temozolomide(TMZ) |
modulate |
4.0 |
27878252 |
acc1686 |
ERK2 |
phosphorylation |
Tyr187 |
human |
glioma |
C6 |
temozolomide(TMZ) |
modulate |
4.0 |
27878252 |
acc1687 |
ERK1 |
phosphorylation |
Thr202 |
human |
glioma |
C6 |
U0126 |
inhibit |
5.0 |
27878252 |
acc1688 |
ERK1 |
phosphorylation |
Tyr204 |
human |
glioma |
C6 |
U0126 |
inhibit |
5.0 |
27878252 |
acc1689 |
ERK2 |
phosphorylation |
Thr185 |
human |
glioma |
C6 |
U0126 |
inhibit |
5.0 |
27878252 |
acc1690 |
ERK2 |
phosphorylation |
Tyr187 |
human |
glioma |
C6 |
U0126 |
inhibit |
5.0 |
27878252 |
acc1691 |
ERK1 |
phosphorylation |
Thr202 |
human |
stomach cancer |
|
Vitamin K3 |
modulate |
4.0 |
12678906 |
acc1692 |
ERK1 |
phosphorylation |
Tyr204 |
human |
stomach cancer |
|
Vitamin K3 |
modulate |
4.0 |
12678906 |
acc1693 |
ERK2 |
phosphorylation |
Thr185 |
human |
stomach cancer |
|
Vitamin K3 |
modulate |
4.0 |
12678906 |
acc1694 |
ERK2 |
phosphorylation |
Tyr187 |
human |
stomach cancer |
|
Vitamin K3 |
modulate |
4.0 |
12678906 |
acc1695 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HCT116 |
DHA + ISL |
modulate |
4.0 |
33502699 |
acc1696 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HCT116 |
DHA + ISL |
modulate |
4.0 |
33502699 |
acc1697 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HCT116 |
DHA + ISL |
modulate |
4.0 |
33502699 |
acc1698 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HCT116 |
DHA + ISL |
modulate |
4.0 |
33502699 |
acc1699 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
A2780AD |
PTX |
resist |
5.0 |
29693189 |
acc1700 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
A2780AD |
PTX |
resist |
5.0 |
29693189 |
acc1701 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
A2780AD |
PTX |
resist |
5.0 |
29693189 |
acc1702 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
A2780AD |
PTX |
resist |
5.0 |
29693189 |
acc1703 |
pRB |
phosphorylation |
Ser795 |
human |
lung cancer |
Ma-10 |
paclitaxel |
sensitize |
5.0 |
15138593 |
acc1704 |
pRB |
phosphorylation |
Ser795 |
human |
lung cancer |
Ma-31 |
paclitaxel |
sensitize |
5.0 |
15138593 |
acc1705 |
SHP2 |
phosphorylation |
Tyr62 |
human |
leukemia |
MOLM-13 |
SHP099 |
resist |
5.0 |
35311954 |
acc1706 |
SHP2 |
phosphorylation |
Tyr62 |
human |
leukemia |
MV4-11 |
SHP099 |
resist |
5.0 |
35311954 |
acc1707 |
ERK1 |
phosphorylation |
Thr202 |
human |
prostate cancer |
PC3 |
bortezomib |
modulate |
4.0 |
34363546 |
acc1708 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT29 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1709 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT29 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1710 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT29 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1711 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT29 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1712 |
Drp1 |
phosphorylation |
Ser616 |
human |
colorectal cancer |
HT29 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1713 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HCT116 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1714 |
ERK2 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HCT116 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1715 |
ERK1 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HCT116 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1716 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HCT116 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1717 |
Drp1 |
phosphorylation |
Ser616 |
human |
colorectal cancer |
HCT116 |
Paris Saponin II(PSII) |
modulate |
4.0 |
30471409 |
acc1718 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
A549 |
Thymoquinone |
modulate |
4.0 |
25238880 |
acc1719 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
A549 |
Thymoquinone |
modulate |
4.0 |
25238880 |
acc1720 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
A549 |
Thymoquinone |
modulate |
4.0 |
25238880 |
acc1721 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
A549 |
Thymoquinone |
modulate |
4.0 |
25238880 |
acc1722 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
HL-60 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1723 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
HL-60 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1724 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
HL-60 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1725 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
HL-60 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1726 |
ERK1 |
phosphorylation |
Thr202 |
human |
leukemia |
K562 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1727 |
ERK1 |
phosphorylation |
Tyr204 |
human |
leukemia |
K562 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1728 |
ERK2 |
phosphorylation |
Thr185 |
human |
leukemia |
K562 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1729 |
ERK2 |
phosphorylation |
Tyr187 |
human |
leukemia |
K562 |
Shikonin |
inhibit |
5.0 |
22837689 |
acc1730 |
ERK1 |
phosphorylation |
Thr202 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1731 |
ERK1 |
phosphorylation |
Tyr204 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1732 |
ERK2 |
phosphorylation |
Thr185 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1733 |
ERK2 |
phosphorylation |
Tyr187 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1734 |
AKT |
phosphorylation |
Tyr347 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1735 |
BAD |
phosphorylation |
Ser136 |
human |
osteosarcoma |
|
quercetin(QUE) |
modulate |
4.0 |
35447220 |
acc1736 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
SK-Mel-28 |
NHWD-870 |
inhibit |
5.0 |
35184394 |
acc1737 |
STAT3 |
phosphorylation |
Ser727 |
human |
melanoma |
SK-Mel-28 |
NHWD-870 |
inhibit |
5.0 |
35184394 |
acc1738 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
A375 |
NHWD-870 |
inhibit |
5.0 |
35184394 |
acc1739 |
STAT3 |
phosphorylation |
Ser727 |
human |
melanoma |
A375 |
NHWD-870 |
inhibit |
5.0 |
35184394 |
acc1740 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MCF7 |
U0126 |
inhibit |
5.0 |
15231676 |
acc1741 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MCF7 |
U0126 |
inhibit |
5.0 |
15231676 |
acc1742 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF7 |
U0126 |
inhibit |
5.0 |
15231676 |
acc1743 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MCF7 |
U0126 |
inhibit |
5.0 |
15231676 |
acc1744 |
ER alpha |
phosphorylation |
Ser118 |
human |
breast cancer |
|
tamoxifen |
benefit |
5.0 |
19940281 |
acc1745 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
HuH-7 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1746 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HuH-7 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1747 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
HuH-7 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1748 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
HuH-7 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1749 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
HepG2 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1750 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
HepG2 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1751 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
HepG2 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1752 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
HepG2 |
isofraxidin |
modulate |
4.0 |
20930381 |
acc1753 |
Bad |
phosphorylation |
Ser75 |
human |
melanoma |
A2058 |
BAY 43-9006(sorafenib) |
modulate |
4.0 |
16452220 |
acc1754 |
Bad |
phosphorylation |
Ser99 |
human |
melanoma |
A2058 |
BAY 43-9006(sorafenib) |
modulate |
4.0 |
16452220 |
acc1755 |
Bad |
phosphorylation |
Ser75 |
human |
melanoma |
SK-MEL-5 |
BAY 43-9006(sorafenib) |
modulate |
4.0 |
16452220 |
acc1756 |
Bad |
phosphorylation |
Ser99 |
human |
melanoma |
SK-MEL-5 |
BAY 43-9006(sorafenib) |
modulate |
4.0 |
16452220 |
acc1757 |
EZH2 |
phosphorylation |
Ser21 |
human |
breast cancer |
MCF7 |
tamoxifen |
resist |
5.0 |
36356296 |
acc1758 |
FAK |
phosphorylation |
Tyr925 |
human |
meningioma |
IOMM-Lee |
pUC |
modulate |
4.0 |
21347260 |
acc1759 |
FAK |
phosphorylation |
Tyr925 |
human |
meningioma |
CH-157MN |
pUC |
modulate |
4.0 |
21347260 |
acc1760 |
FAK |
phosphorylation |
Tyr397 |
human |
glioma |
LN229 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1761 |
IGF-IR |
phosphorylation |
Tyr1135 |
human |
glioma |
LN229 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1762 |
IGF-IR |
phosphorylation |
Tyr1136 |
human |
glioma |
LN229 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1763 |
FAK |
phosphorylation |
Tyr397 |
human |
glioma |
U87 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1764 |
IGF-IR |
phosphorylation |
Tyr1135 |
human |
glioma |
U87 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1765 |
IGF-IR |
phosphorylation |
Tyr1136 |
human |
glioma |
U87 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1766 |
FAK |
phosphorylation |
Tyr397 |
human |
glioma |
U251 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1767 |
IGF-IR |
phosphorylation |
Tyr1135 |
human |
glioma |
U251 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1768 |
IGF-IR |
phosphorylation |
Tyr1136 |
human |
glioma |
U251 |
TAE226 |
modulate |
4.0 |
17431114 |
acc1769 |
c-Myc |
phosphorylation |
Ser62 |
human |
cholangiocarcinoma |
QBC939 |
PD98059 |
modulate |
4.0 |
20101459 |
acc1770 |
FAK |
phosphorylation |
Tyr397 |
human |
myeloma |
MM1 |
palmitoyl-cyclic phosphatidic acid (Pal-cPA) |
modulate |
4.0 |
12738990 |
acc1771 |
FAK |
phosphorylation |
Tyr397 |
mouse |
melanoma |
B16 |
palmitoyl-cyclic phosphatidic acid (Pal-cPA) |
modulate |
4.0 |
12738990 |
acc1772 |
FOXO1 |
phosphorylation |
Ser256 |
human |
breast cancer |
SUM159PT |
Cold atmospheric plasma (CAP) |
modulate |
4.0 |
35637961 |
acc1773 |
FOXO1 |
phosphorylation |
Thr24 |
human |
colon cancer |
HT29 |
rapamycin |
inhibit |
5.0 |
20392999 |
acc1774 |
FOXO1 |
phosphorylation |
Thr24 |
human |
colon cancer |
LS174T |
rapamycin |
inhibit |
5.0 |
20392999 |
acc1775 |
HER2 |
phosphorylation |
Tyr1248 |
human |
breast cancer |
BT474 |
trastuzumab |
reduce |
5.0 |
21803025 |
acc1776 |
HER2 |
phosphorylation |
Tyr1248 |
human |
breast cancer |
SK-BR-3 |
trastuzumab |
reduce |
5.0 |
21803025 |
acc1777 |
EGFR |
phosphorylation |
Tyr845 |
human |
lung cancer |
H1299 |
- |
resist |
3.0 |
33706413 |
acc1778 |
GPNMB |
glycosylation |
Asn134 |
human |
lung cancer |
H1299 |
- |
resist |
3.0 |
33706413 |
acc1779 |
53BP1 |
phosphorylation |
Ser166 |
human |
glioblastoma |
U87 |
ionizing radiation + SB216763 |
modulate |
4.0 |
29328365 |
acc1780 |
53BP1 |
phosphorylation |
Ser166 |
human |
glioblastoma |
U87 |
ionizing radiation |
inhibit |
4.5 |
29328365 |
acc1781 |
STAT3 |
phosphorylation |
Tyr705 |
human |
head and neck cancer |
Tu212 |
erlotinib |
modulate |
4.0 |
24019973 |
acc1782 |
STAT3 |
phosphorylation |
Tyr705 |
human |
head and neck cancer |
Tu686 |
erlotinib |
modulate |
4.0 |
24019973 |
acc1783 |
STAT3 |
phosphorylation |
Tyr705 |
human |
head and neck cancer |
Tu212 |
erlotinib |
resist |
5.0 |
24019973 |
acc1784 |
STAT3 |
phosphorylation |
Tyr705 |
human |
head and neck cancer |
Tu686 |
erlotinib |
resist |
5.0 |
24019973 |
acc1785 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
MCF7 |
rapalogues |
increase |
5.0 |
24204783 |
acc1786 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
MDA-MB-231 |
rapalogues |
increase |
5.0 |
24204783 |
acc1787 |
GSK3beta |
phosphorylation |
Ser9 |
human |
neuroblastoma |
SH-SY5Y |
FK506(calcineurin inhibitors) |
modulate |
3.0 |
19659461 |
acc1788 |
GSK3beta |
phosphorylation |
Ser9 |
human |
neuroblastoma |
SH-SY5Y |
cyclosporin A (CsA) |
modulate |
3.0 |
19659461 |
acc1789 |
GSK3beta |
phosphorylation |
Ser9 |
human |
breast cancer |
MCF7(TamR) |
tamoxifen |
modulate |
4.0 |
21044952 |
acc1790 |
GSK3beta |
phosphorylation |
Ser9 |
human |
colorectal cancer |
HCT116 |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1791 |
GSK3beta |
phosphorylation |
Ser9 |
human |
glioblastoma |
U87-MG |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1792 |
GSK3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
PC3 |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1793 |
AKT |
phosphorylation |
Thr308 |
human |
colorectal cancer |
HCT116 |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1794 |
AKT |
phosphorylation |
Thr308 |
human |
glioblastoma |
U87-MG |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1795 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
PC3 |
Enzastaurin |
modulate |
4.0 |
16103100 |
acc1796 |
GSTP1 |
phosphorylation |
Tyr7 |
human |
breast cancer |
SUM 149 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1797 |
GSTP1 |
phosphorylation |
Tyr7 |
human |
glioma |
MGR1 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1798 |
GSTP1 |
phosphorylation |
Tyr7 |
human |
glioma |
MGR3 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1799 |
GSTP1 |
phosphorylation |
Tyr7 |
human |
glioblastoma |
U87-MG |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1800 |
GSTP1 |
phosphorylation |
Tyr198 |
human |
breast cancer |
SUM 149 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1801 |
GSTP1 |
phosphorylation |
Tyr198 |
human |
breast cancer |
SUM 149 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1802 |
GSTP1 |
phosphorylation |
Tyr198 |
human |
glioma |
MGR3 |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1803 |
GSTP1 |
phosphorylation |
Tyr198 |
human |
glioma |
U87-MG |
Cisplatin |
decrease |
5.0 |
19254954 |
acc1804 |
p65 |
acetylation |
Lys310 |
human |
pancreas cancer |
PANC-1 |
ICB |
sensitize |
4.5 |
35265200 |
acc1805 |
p65 |
acetylation |
Lys310 |
human |
pancreas cancer |
MIA PaCa-2 |
ICB |
sensitize |
4.5 |
35265200 |
acc1806 |
MtCK1 |
phosphorylation |
Tyr153 |
human |
breast cancer |
SK-BR-3 |
lapatinib |
inhibit |
5.0 |
30174304 |
acc1807 |
MtCK1 |
phosphorylation |
Tyr153 |
human |
breast cancer |
BT474(trastuzumab-resistant) |
lapatinib |
inhibit |
5.0 |
30174304 |
acc1808 |
ERK1 |
phosphorylation |
Thr202 |
human |
endometrial cancer |
Ishikawa |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1809 |
ERK1 |
phosphorylation |
Tyr204 |
human |
endometrial cancer |
Ishikawa |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1810 |
ERK2 |
phosphorylation |
Thr185 |
human |
endometrial cancer |
Ishikawa |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1811 |
ERK2 |
phosphorylation |
Tyr187 |
human |
endometrial cancer |
Ishikawa |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1812 |
ERK1 |
phosphorylation |
Thr202 |
human |
endometrial cancer |
HEC-1A |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1813 |
ERK1 |
phosphorylation |
Tyr204 |
human |
endometrial cancer |
HEC-1A |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1814 |
ERK2 |
phosphorylation |
Thr185 |
human |
endometrial cancer |
HEC-1A |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1815 |
ERK2 |
phosphorylation |
Tyr187 |
human |
endometrial cancer |
HEC-1A |
trastuzumab |
inhibit |
5.0 |
12763221 |
acc1816 |
HER2 |
phosphorylation |
Tyr1221 |
human |
breast cancer |
MDA-MB-453m1 |
SUCI02 |
modulate |
4.0 |
12917021 |
acc1817 |
HER2 |
phosphorylation |
Tyr1222 |
human |
breast cancer |
MDA-MB-453m1 |
SUCI02 |
modulate |
4.0 |
12917021 |
acc1818 |
HER2 |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-231 |
emodin |
modulate |
4.0 |
10037184 |
acc1819 |
HER2 |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-231 |
paclitaxel |
inhibit |
5.0 |
10037184 |
acc1820 |
HER2 |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-361 |
emodin |
modulate |
4.0 |
10037184 |
acc1821 |
HER2 |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-361 |
paclitaxel |
inhibit |
5.0 |
10037184 |
acc1822 |
histone H4 |
acetylation |
unclear |
human |
prostate cancer |
C4-2 |
enzalutamide |
resist |
4.0 |
34323404 |
acc1823 |
histone H4 |
acetylation |
unclear |
human |
prostate cancer |
22Rv1 |
enzalutamide |
resist |
4.0 |
34323404 |
acc1824 |
histone H4 |
acetylation |
unclear |
human |
prostate cancer |
LNCaP |
enzalutamide |
resist |
4.0 |
34323404 |
acc1825 |
histone H3 |
methylation |
Lys27 |
human |
leukemia |
HL-60 |
ATRA |
modulate |
3.0 |
19578722 |
acc1826 |
histone H4 |
acetylation |
unclear |
human |
leukemia |
HL-60 |
ATRA |
modulate |
3.0 |
19578722 |
acc1827 |
IDO |
acetylation |
unclear |
human |
nasopharyngeal carcinoma |
CNE2 |
NaB |
modulate |
4.0 |
25854569 |
acc1828 |
IDO |
acetylation |
unclear |
human |
nasopharyngeal carcinoma |
CNE2 |
NaB |
modulate |
4.0 |
25854569 |
acc1829 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H358 |
gefitinib |
resist |
5.0 |
24374738 |
acc1830 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H322 |
gefitinib |
resist |
5.0 |
24374738 |
acc1831 |
Ku70 |
acetylation |
unclear |
human |
lung cancer |
H358 |
gefitinib |
enhance |
5.0 |
24374738 |
acc1832 |
Ku70 |
acetylation |
unclear |
human |
lung cancer |
H322 |
gefitinib |
enhance |
5.0 |
24374738 |
acc1833 |
NF-kappaB's RelA |
acetylation |
Lys310 |
human |
breast cancer |
MDA-MB-231 |
13a |
modulate |
4.0 |
34378541 |
acc1834 |
p53 |
acetylation |
Lys382 |
human |
glioblastoma |
U251 |
DWP0016 |
enhance |
5.0 |
23297003 |
acc1835 |
p53 |
acetylation |
Lys370 |
human |
colon cancer |
HCT116 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1836 |
p53 |
acetylation |
Lys372 |
human |
colon cancer |
HCT116 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1837 |
p53 |
acetylation |
Lys370 |
human |
breast cancer |
MCF7 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1838 |
p53 |
acetylation |
Lys372 |
human |
breast cancer |
MCF7 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1839 |
p53 |
acetylation |
Lys373 |
human |
breast cancer |
MCF7 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1840 |
p53 |
acetylation |
Lys381 |
human |
breast cancer |
MCF7 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1841 |
p53 |
acetylation |
Lys382 |
human |
breast cancer |
MCF7 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1842 |
p53 |
acetylation |
Lys373 |
human |
colon cancer |
HCT116 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1843 |
p53 |
acetylation |
Lys381 |
human |
colon cancer |
HCT116 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1844 |
p53 |
acetylation |
Lys382 |
human |
colon cancer |
HCT116 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1845 |
p53 |
acetylation |
Lys370 |
human |
lung cancer |
A549 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1846 |
p53 |
acetylation |
Lys372 |
human |
lung cancer |
A549 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1847 |
p53 |
acetylation |
Lys373 |
human |
lung cancer |
A549 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1848 |
p53 |
acetylation |
Lys381 |
human |
lung cancer |
A549 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1849 |
p53 |
acetylation |
Lys382 |
human |
lung cancer |
A549 |
MS-275 |
modulate |
4.0 |
36257192 |
acc1850 |
SKP2 |
acetylation |
Lys68 |
human |
prostate cancer |
LNCaP |
dihydrotestosterone (DHT) |
modulate |
4.0 |
36871351 |
acc1851 |
SKP2 |
acetylation |
Lys71 |
human |
prostate cancer |
LNCaP |
dihydrotestosterone (DHT) |
modulate |
4.0 |
36871351 |
acc1852 |
SKP2 |
acetylation |
Lys68 |
human |
prostate cancer |
C4-2 |
dihydrotestosterone (DHT) |
modulate |
4.0 |
36871351 |
acc1853 |
SKP2 |
acetylation |
Lys71 |
human |
prostate cancer |
C4-2 |
dihydrotestosterone (DHT) |
modulate |
4.0 |
36871351 |
acc1854 |
histone H3 |
methylation |
Lys9 |
human |
colon cancer |
SW480 |
Mithramycin |
modulate |
3.0 |
32473242 |
acc1855 |
histone H3 |
methylation |
Lys9 |
human |
colon cancer |
LoVo |
Mithramycin |
modulate |
3.0 |
32473242 |
acc1856 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
SW480 |
cetuximab |
inhibit |
5.0 |
32473242 |
acc1857 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
LoVo |
cetuximab |
inhibit |
5.0 |
32473242 |
acc1858 |
AKT |
phosphorylation |
Tyr308 |
human |
colon cancer |
SW480 |
cetuximab |
inhibit |
5.0 |
32473242 |
acc1859 |
AKT |
phosphorylation |
Tyr308 |
human |
colon cancer |
LoVo |
cetuximab |
inhibit |
5.0 |
32473242 |
acc1860 |
MST1 |
methylation |
Lys59 |
human |
breast cancer |
MDA-MB-231 |
neuregulin |
modulate |
4.0 |
28114269 |
acc1861 |
HER3 |
methylation |
Tyr1307 |
human |
breast cancer |
MDA-MB-231 |
neuregulin |
modulate |
4.0 |
28114269 |
acc1862 |
HSP70 |
methylation |
Arg416 |
human |
pancreas cancer |
MIA PaCa-2 |
gemcitabine |
resist |
5.0 |
32699135 |
acc1863 |
HSP70 |
methylation |
Arg447 |
human |
pancreas cancer |
MIA PaCa-2 |
gemcitabine |
resist |
5.0 |
32699135 |
acc1864 |
ULK1 |
methylation |
Arg170 |
human |
lung cancer |
A549 |
carboplatin |
resist |
5.0 |
37381616 |
acc1865 |
ULK1 |
methylation |
Arg170 |
human |
lung cancer |
NCI-H1975 |
carboplatin |
resist |
5.0 |
37381616 |
acc1866 |
RNF4 |
methylation |
Arg164 |
human |
leukemia |
NB-4 |
As2O3 |
resist |
5.0 |
35622143 |
acc1867 |
mTOR |
phosphorylation |
Ser2448 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1868 |
mTOR |
phosphorylation |
Ser2448 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1869 |
4EBP1 |
phosphorylation |
Thr46 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1870 |
4EBP1 |
phosphorylation |
Thr46 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1871 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1872 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1873 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1874 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1875 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1876 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1877 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1878 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1879 |
mTOR |
phosphorylation |
Ser2448 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1880 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1881 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1882 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1883 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1884 |
p70s6K |
phosphorylation |
Thr389 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1885 |
p70s6K |
phosphorylation |
Thr389 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1886 |
p70s6K |
phosphorylation |
Thr389 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1887 |
4EBP1 |
phosphorylation |
Thr37 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1888 |
4EBP1 |
phosphorylation |
Thr37 |
human |
colorectal cancer |
HT29 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1889 |
4EBP1 |
phosphorylation |
Thr37 |
human |
colorectal cancer |
HCT116 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1890 |
4EBP1 |
phosphorylation |
Thr46 |
human |
colorectal cancer |
SW480 |
PD98059 + rapamycin |
modulate |
4.0 |
19194827 |
acc1891 |
mTOR |
phosphorylation |
Ser2448 |
human |
pancreas cancer |
CFPAC-1 |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1892 |
4EBP1 |
phosphorylation |
Thr37 |
human |
pancreas cancer |
CFPAC-1 |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1893 |
4EBP1 |
phosphorylation |
Thr46 |
human |
pancreas cancer |
CFPAC-1 |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1894 |
mTOR |
phosphorylation |
Ser2448 |
human |
pancreas cancer |
BxPC-3(gemcitabine R) |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1895 |
4EBP1 |
phosphorylation |
Thr37 |
human |
pancreas cancer |
BxPC-3(gemcitabine R) |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1896 |
4EBP1 |
phosphorylation |
Thr46 |
human |
pancreas cancer |
BxPC-3(gemcitabine R) |
pralatrexate |
modulate |
4.0 |
36544829 |
acc1897 |
CUL1 |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1898 |
CUL2 |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1899 |
CUL3 |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1900 |
CUL4A |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1901 |
CUL4B |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1902 |
CUL5 |
neddylation |
unclear |
human |
lung cancer |
H1299 |
MLN4924 |
resist |
5.0 |
31208947 |
acc1903 |
LCK |
nitration |
Tyr394 |
mouse |
lung cancer |
Lewis |
ICB |
inhibit |
4.5 |
30232256 |
acc1904 |
LCK |
nitration |
Tyr394 |
mouse |
prostate cancer |
|
ICB |
inhibit |
4.5 |
30232256 |
acc1905 |
BCL2 |
phosphorylation |
Ser70 |
human |
myeloma |
ARP-1 |
bortezomib |
inhibit |
5.0 |
27924158 |
acc1906 |
BCL2 |
phosphorylation |
Ser70 |
human |
myeloma |
ANBL6 |
bortezomib |
inhibit |
5.0 |
27924158 |
acc1907 |
Hsp27 |
phosphorylation |
Ser78 |
human |
leukemia |
THP-1 |
apigenin |
inhibit |
5.0 |
21364669 |
acc1908 |
Hsp27 |
phosphorylation |
Ser82 |
human |
leukemia |
THP-1 |
apigenin |
inhibit |
5.0 |
21364669 |
acc1909 |
HSP27 |
phosphorylation |
Ser15 |
human |
lung cancer |
SK-MES-1 |
dioscin |
modulate |
4.0 |
33061803 |
acc1910 |
HSP27 |
phosphorylation |
Ser15 |
human |
lung cancer |
NCI-H520 |
dioscin |
modulate |
4.0 |
33061803 |
acc1911 |
IGF-1R |
phosphorylation |
Tyr1131 |
human |
sarcoma |
|
SCH717454 |
modulate |
4.0 |
22188815 |
acc1912 |
IGF1R |
phosphorylation |
Tyr1135 |
human |
sarcoma |
U2OS |
mitoxantrone |
inhibit |
5.0 |
34110249 |
acc1913 |
IGF1R |
phosphorylation |
Tyr1136 |
human |
sarcoma |
U2OS |
mitoxantrone |
inhibit |
5.0 |
34110249 |
acc1914 |
IGF1R |
phosphorylation |
Tyr1135 |
mouse |
sarcoma |
MCA205 |
mitoxantrone |
inhibit |
5.0 |
34110249 |
acc1915 |
IGF1R |
phosphorylation |
Tyr1136 |
mouse |
sarcoma |
MCA205 |
mitoxantrone |
inhibit |
5.0 |
34110249 |
acc1916 |
IGF1R |
phosphorylation |
Tyr1135 |
mouse |
sarcoma |
MCA205 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1917 |
IGF1R |
phosphorylation |
Tyr1136 |
mouse |
sarcoma |
MCA205 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1918 |
IGF1R |
phosphorylation |
Tyr1135 |
mouse |
breast cancer |
AT3 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1919 |
IGF1R |
phosphorylation |
Tyr1136 |
mouse |
breast cancer |
AT3 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1920 |
IGF1R |
phosphorylation |
Tyr1135 |
mouse |
lung cancer |
TC1 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1921 |
IGF1R |
phosphorylation |
Tyr1136 |
mouse |
lung cancer |
TC1 |
oxaliplatin (OXA) |
inhibit |
5.0 |
34110249 |
acc1922 |
IGFBP-3 |
phosphorylation |
Ser |
human |
lung cancer |
A549 |
Cisplatin |
inhibit |
5.0 |
36766747 |
acc1923 |
IGFBP-3 |
phosphorylation |
Ser |
human |
lung cancer |
H1299 |
Cisplatin |
inhibit |
5.0 |
36766747 |
acc1924 |
IRS-1 |
phosphorylation |
Ser312 |
human |
breast cancer |
MCF7 |
anisomycin |
modulate |
3.0 |
15952059 |
acc1925 |
BCL2 |
phosphorylation |
Ser70 |
human |
breast cancer |
Bcap37 |
paclitaxel |
enhance |
5.0 |
17568189 |
acc1926 |
BCL2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
OV2008 |
paclitaxel |
enhance |
5.0 |
17568189 |
acc1927 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colon cancer |
HCT116 |
Evista (Raloxifene¡¤HCl) |
modulate |
4.0 |
28711499 |
acc1928 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
Evista (Raloxifene¡¤HCl) |
modulate |
4.0 |
28711499 |
acc1929 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
SUM159 |
Evista (Raloxifene¡¤HCl) |
modulate |
4.0 |
28711499 |
acc1930 |
mTOR |
phosphorylation |
Ser2448 |
human |
cervical cancer |
HeLa |
angelicin |
modulate |
4.0 |
31602210 |
acc1931 |
mTOR |
phosphorylation |
Ser2448 |
human |
cervical cancer |
SiHa |
angelicin |
modulate |
4.0 |
31602210 |
acc1932 |
STAT3 |
phosphorylation |
Tyr705 |
human |
oral cancer |
SAS |
Cisplatin |
suppress |
5.0 |
33551310 |
acc1933 |
STAT3 |
phosphorylation |
Tyr705 |
human |
oral cancer |
GNM |
Cisplatin |
suppress |
5.0 |
33551310 |
acc1934 |
STAT3 |
phosphorylation |
Tyr705 |
human |
oral cancer |
SAS |
magnolol |
modulate |
4.0 |
33551310 |
acc1935 |
STAT3 |
phosphorylation |
Tyr705 |
human |
oral cancer |
GNM |
magnolol |
modulate |
4.0 |
33551310 |
acc1936 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
Rh30 |
Celecoxib |
modulate |
4.0 |
21397587 |
acc1937 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
RH28 |
Celecoxib |
modulate |
4.0 |
21397587 |
acc1938 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
RD2 |
Celecoxib |
modulate |
4.0 |
21397587 |
acc1939 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
PEITC |
modulate |
4.0 |
19437484 |
acc1940 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
LNCaP |
PEITC |
modulate |
4.0 |
19437484 |
acc1941 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
PEITC |
modulate |
4.0 |
19437484 |
acc1942 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
LNCaP |
PEITC |
modulate |
4.0 |
19437484 |
acc1943 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
PEITC |
modulate |
4.0 |
19437484 |
acc1944 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
LNCaP |
PEITC |
modulate |
4.0 |
19437484 |
acc1945 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
B12 |
modulate |
4.0 |
33774344 |
acc1946 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colon cancer |
HCT116 |
B12 |
modulate |
4.0 |
33774344 |
acc1947 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colon cancer |
SW480 |
B12 |
modulate |
4.0 |
33774344 |
acc1948 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
L3.6pl |
B12 |
modulate |
4.0 |
33774344 |
acc1949 |
STAT3 |
phosphorylation |
Tyr705 |
human |
thyroid cancer |
NPA-87 |
phenylmethimazole(C10) |
modulate |
4.0 |
17525119 |
acc1950 |
STAT3 |
phosphorylation |
Ser727 |
human |
thyroid cancer |
NPA-87 |
phenylmethimazole(C10) |
modulate |
4.0 |
17525119 |
acc1951 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
|
gemcitabine |
inhibit |
5.0 |
27003603 |
acc1952 |
IRS-1 |
phosphorylation |
Tyr |
human |
hepatocellular carcinoma |
FOCUS |
ethanol |
modulate |
3.0 |
9884156 |
acc1953 |
erbB-2 |
phosphorylation |
Tyr |
human |
ovarian cancer |
SK-OV-3 |
IFN-gamma |
modulate |
4.0 |
7914514 |
acc1954 |
STAT3 |
phosphorylation |
Tyr705 |
human |
glioblastoma |
GBM4 |
SAR317461 |
modulate |
4.0 |
26283544 |
acc1955 |
STAT3 |
phosphorylation |
Tyr705 |
human |
glioblastoma |
GBM8 |
SAR317461 |
modulate |
4.0 |
26283544 |
acc1956 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HCT116 |
SC-43 |
modulate |
4.0 |
30109144 |
acc1957 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HT29 |
SC-43 |
modulate |
4.0 |
30109144 |
acc1958 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HCT116 |
SC-78 |
modulate |
4.0 |
30109144 |
acc1959 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HT29 |
SC-78 |
modulate |
4.0 |
30109144 |
acc1960 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
Tanshinone I |
modulate |
4.0 |
26202747 |
acc1961 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
Hep3B |
ursolic acid (UA) |
modulate |
4.0 |
28714512 |
acc1962 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
HepG2 |
ursolic acid (UA) |
modulate |
4.0 |
28714512 |
acc1963 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
SSMC-7721 |
ursolic acid (UA) |
modulate |
4.0 |
28714512 |
acc1964 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
HuH-7 |
ursolic acid (UA) |
modulate |
4.0 |
28714512 |
acc1965 |
ULK1 |
phosphorylation |
Ser757 |
human |
melanoma |
A375 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1966 |
ULK1 |
phosphorylation |
Ser555 |
human |
melanoma |
A375 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1967 |
ULK1 |
phosphorylation |
Ser317 |
human |
melanoma |
A375 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1968 |
ULK1 |
phosphorylation |
Ser757 |
human |
melanoma |
SK-Mel-28 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1969 |
ULK1 |
phosphorylation |
Ser555 |
human |
melanoma |
SK-Mel-28 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1970 |
ULK1 |
phosphorylation |
Ser317 |
human |
melanoma |
SK-Mel-28 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1971 |
ULK1 |
phosphorylation |
Ser757 |
human |
melanoma |
SK-MEL-1 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1972 |
ULK1 |
phosphorylation |
Ser555 |
human |
melanoma |
SK-MEL-1 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1973 |
ULK1 |
phosphorylation |
Ser317 |
human |
melanoma |
SK-MEL-1 |
p53 upregulated regulator of p53 levels (PURPL) |
modulate |
3.0 |
34759263 |
acc1974 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
LLL12 |
modulate |
4.0 |
20072652 |
acc1975 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
SK-BR-3 |
LLL12 |
modulate |
4.0 |
20072652 |
acc1976 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
PANC-1 |
LLL12 |
modulate |
4.0 |
20072652 |
acc1977 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
HPAC |
LLL12 |
modulate |
4.0 |
20072652 |
acc1978 |
STAT3 |
phosphorylation |
Tyr705 |
human |
glioblastoma |
U87 |
LLL12 |
modulate |
4.0 |
20072652 |
acc1979 |
STAT3 |
phosphorylation |
Tyr705 |
human |
glioblastoma |
U373 |
LLL12 |
modulate |
4.0 |
20072652 |
acc1980 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
LLL12 + doxorubicin |
modulate |
4.0 |
20072652 |
acc1981 |
STAT3 |
phosphorylation |
Tyr705 |
human |
pancreas cancer |
HPAC |
LLL12 + gemcitabine |
modulate |
4.0 |
20072652 |
acc1982 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
A549 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1983 |
STAT3 |
phosphorylation |
Ser727 |
human |
lung cancer |
A549 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1984 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
H441 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1985 |
STAT3 |
phosphorylation |
Ser727 |
human |
lung cancer |
H441 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1986 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
H292 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1987 |
STAT3 |
phosphorylation |
Ser727 |
human |
lung cancer |
H292 |
Pyrvinium pamoate |
modulate |
4.0 |
32298693 |
acc1988 |
STAT3 |
phosphorylation |
Tyr705 |
human |
neuroblastoma |
SH-SY5Y |
ethanol |
modulate |
3.0 |
26206265 |
acc1989 |
STAT3 |
phosphorylation |
Tyr705 |
human |
neuroblastoma |
IMR-32 |
ethanol |
modulate |
3.0 |
26206265 |
acc1990 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
HL-60 |
rapamycin |
modulate |
4.0 |
35116779 |
acc1991 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
THP-1 |
rapamycin |
modulate |
4.0 |
35116779 |
acc1992 |
STAT3 |
phosphorylation |
Tyr727 |
human |
leukemia |
HL-60 |
rapamycin |
modulate |
4.0 |
35116779 |
acc1993 |
STAT3 |
phosphorylation |
Tyr727 |
human |
leukemia |
THP-1 |
rapamycin |
modulate |
4.0 |
35116779 |
acc1994 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
Daoy |
SPARC OV |
modulate |
3.0 |
21613407 |
acc1995 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
D283 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc1996 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
H2405 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc1997 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
H2411 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc1998 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
UW228 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc1999 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
D425 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2000 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
H2405 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2001 |
STAT3 |
phosphorylation |
Tyr705 |
human |
medulloblastoma |
H2411 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2002 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
Daoy |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2003 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
D283 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2004 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
UW228 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2005 |
STAT3 |
phosphorylation |
Tyr727 |
human |
medulloblastoma |
D425 |
SPARC OV |
modulate |
3.0 |
21613407 |
acc2006 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colorectal cancer |
HCT116 |
doxorubicin |
sensitize |
5.0 |
20026083 |
acc2007 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-231 |
doxorubicin |
sensitize |
5.0 |
20026083 |
acc2008 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
HeLa |
doxorubicin |
sensitize |
5.0 |
20026083 |
acc2009 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HepG2 |
doxorubicin |
sensitize |
5.0 |
20026083 |
acc2010 |
PIN1 |
phosphorylation |
Ser115 |
human |
cholangiocarcinoma |
|
retinoic acid |
modulate |
4.0 |
34048060 |
acc2011 |
JNK1 |
phosphorylation |
Thr183 |
human |
hepatocellular carcinoma |
HuH-7 |
resveratrol |
modulate |
4.0 |
23437203 |
acc2012 |
JNK1 |
phosphorylation |
Tyr185 |
human |
hepatocellular carcinoma |
HuH-7 |
resveratrol |
modulate |
4.0 |
23437203 |
acc2013 |
JNK2 |
phosphorylation |
Thr183 |
human |
hepatocellular carcinoma |
HuH-7 |
resveratrol |
modulate |
4.0 |
23437203 |
acc2014 |
JNK2 |
phosphorylation |
Tyr185 |
human |
hepatocellular carcinoma |
HuH-7 |
resveratrol |
modulate |
4.0 |
23437203 |
acc2015 |
KIT |
phosphorylation |
Tyr703 |
human |
lung cancer |
HCC78 |
ponatinib |
modulate |
3.0 |
27068398 |
acc2016 |
KIT |
phosphorylation |
Tyr703 |
human |
lung cancer |
CUTO2 |
ponatinib |
modulate |
3.0 |
27068398 |
acc2017 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HepG2 xenografts |
sorafenib + cucurbitacin B (CuB) |
reduce |
5.0 |
33176070 |
acc2018 |
LASP1 |
phosphorylation |
Tyr171 |
human |
leukemia |
BV173 |
erlotinib |
modulate |
3.0 |
24913448 |
acc2019 |
AMPK |
phosphorylation |
Thr172 |
human |
breast cancer |
MCF7 |
docosahexaenoic acid(DHA) |
modulate |
4.0 |
24025358 |
acc2020 |
AMPK |
phosphorylation |
Thr183 |
human |
breast cancer |
MCF7 |
docosahexaenoic acid(DHA) |
modulate |
4.0 |
24025358 |
acc2021 |
BIM |
phosphorylation |
unclear |
human |
leukemia |
SUPT-1 |
prednisolone |
inhibit |
5.0 |
34007050 |
acc2022 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
SB01-VR |
bafetinib |
modulate |
4.0 |
29717260 |
acc2023 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
SB01-VR |
bafetinib |
modulate |
4.0 |
29717260 |
acc2024 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
SB01-VR |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc2025 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
SB01-VR |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc2026 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
SB01-VR |
bafetinib |
modulate |
4.0 |
29717260 |
acc2027 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
SB01-VR |
bafetinib |
modulate |
4.0 |
29717260 |
acc2028 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
SB01-VR |
trametinib |
modulate |
4.0 |
29717260 |
acc2029 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
SB01-VR |
trametinib |
modulate |
4.0 |
29717260 |
acc2030 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
SB01-VR |
trametinib |
modulate |
4.0 |
29717260 |
acc2031 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
SB01-VR |
trametinib |
modulate |
4.0 |
29717260 |
acc2032 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
SB01-VR |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc2033 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
SB01-VR |
bafetinib + trametinib |
modulate |
4.0 |
29717260 |
acc2034 |
MEK1 |
phosphorylation |
Ser217 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2035 |
MEK1 |
phosphorylation |
Ser221 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2036 |
MEK2 |
phosphorylation |
Ser217 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2037 |
MEK2 |
phosphorylation |
Ser221 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2038 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2039 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2040 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2041 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2042 |
MEK2 |
phosphorylation |
Ser217 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2043 |
MEK2 |
phosphorylation |
Ser221 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2044 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2045 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2046 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2047 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MCF7 |
DHA |
modulate |
4.0 |
21771724 |
acc2048 |
MEK1 |
phosphorylation |
Ser217 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2049 |
MEK1 |
phosphorylation |
Ser221 |
human |
breast cancer |
SK-BR-3 |
DHA |
modulate |
4.0 |
21771724 |
acc2050 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
Calu-6 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2051 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
Calu-6 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2052 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
HCC2450 |
AZD6244 |
inhibit |
5.0 |
19783898 |
acc2053 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
HCC2450 |
AZD6244 |
inhibit |
5.0 |
19783898 |
acc2054 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
Calu-6 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2055 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
Calu-6 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2056 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
HCC2450 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2057 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
HCC2450 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2058 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
HCC2450 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2059 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
HCC2450 |
AZD6244 |
modulate |
4.0 |
19783898 |
acc2060 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H522 |
AZD6244 |
inhibit |
5.0 |
19783898 |
acc2061 |
AKT |
phosphorylation |
Thr308 |
human |
lung cancer |
H522 |
AZD6244 |
inhibit |
5.0 |
19783898 |
acc2062 |
MEK |
phosphorylation |
unclear |
human |
breast cancer |
MCF7 |
silibinin |
modulate |
4.0 |
23353996 |
acc2063 |
ERK |
phosphorylation |
unclear |
human |
breast cancer |
MCF7 |
silibinin |
modulate |
4.0 |
23353996 |
acc2064 |
MEK |
phosphorylation |
unclear |
human |
thyroid cancer |
TPC-1 |
silibinin |
modulate |
4.0 |
23353996 |
acc2065 |
ERK |
phosphorylation |
unclear |
human |
thyroid cancer |
TPC-1 |
silibinin |
modulate |
4.0 |
23353996 |
acc2066 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
HL-60 |
paclitaxel |
modulate |
4.0 |
10400418 |
acc2067 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
U937 |
paclitaxel |
modulate |
4.0 |
10400418 |
acc2068 |
BCL2 |
phosphorylation |
Ser70 |
human |
leukemia |
Jurkat |
paclitaxel |
modulate |
4.0 |
10400418 |
acc2069 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
PC9 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2070 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
PC9 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2071 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
PC9 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2072 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
PC9 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2073 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
HCC827 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2074 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
HCC827 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2075 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
HCC827 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2076 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
HCC827 |
erlotinib |
modulate |
4.0 |
23979919 |
acc2077 |
FAK |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-231 |
Met-F-AEA |
modulate |
4.0 |
16343481 |
acc2078 |
Src |
phosphorylation |
Tyr |
human |
breast cancer |
MDA-MB-231 |
Met-F-AEA |
modulate |
4.0 |
16343481 |
acc2079 |
FAK |
phosphorylation |
Tyr |
mouse |
breast cancer |
TSA-E1 |
Met-F-AEA |
modulate |
4.0 |
16343481 |
acc2080 |
Src |
phosphorylation |
Tyr |
mouse |
breast cancer |
TSA-E1 |
Met-F-AEA |
modulate |
4.0 |
16343481 |
acc2081 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
Sbcl2 |
azacitidine |
modulate |
4.0 |
34866327 |
acc2082 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
Sbcl2 |
azacitidine |
modulate |
4.0 |
34866327 |
acc2083 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
Sbcl2 |
azacitidine + trametinib |
modulate |
4.0 |
34866327 |
acc2084 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
Sbcl2 |
azacitidine + trametinib |
modulate |
4.0 |
34866327 |
acc2085 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
Sbcl2 |
azacitidine |
modulate |
4.0 |
34866327 |
acc2086 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
Sbcl2 |
azacitidine |
modulate |
4.0 |
34866327 |
acc2087 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
Sbcl2 |
trametinib |
modulate |
4.0 |
34866327 |
acc2088 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
Sbcl2 |
trametinib |
modulate |
4.0 |
34866327 |
acc2089 |
ERK2 |
phosphorylation |
Thr185 |
human |
melanoma |
Sbcl2 |
trametinib |
modulate |
4.0 |
34866327 |
acc2090 |
ERK2 |
phosphorylation |
Tyr187 |
human |
melanoma |
Sbcl2 |
trametinib |
modulate |
4.0 |
34866327 |
acc2091 |
ERK1 |
phosphorylation |
Thr202 |
human |
melanoma |
Sbcl2 |
azacitidine + trametinib |
modulate |
4.0 |
34866327 |
acc2092 |
ERK1 |
phosphorylation |
Tyr204 |
human |
melanoma |
Sbcl2 |
azacitidine + trametinib |
modulate |
4.0 |
34866327 |
acc2093 |
MMP-9 |
phosphorylation |
unclear |
human |
breast cancer |
MCF7 |
SFN |
modulate |
4.0 |
35988280 |
acc2094 |
MMP-9 |
phosphorylation |
unclear |
human |
breast cancer |
MDA-MB-231 |
SFN |
modulate |
4.0 |
35988280 |
acc2095 |
eIF4E |
phosphorylation |
Ser209 |
human |
leukemia |
MV4-11 |
merestinib |
modulate |
4.0 |
27307295 |
acc2096 |
eIF4E |
phosphorylation |
Ser209 |
human |
leukemia |
MM6 |
merestinib |
modulate |
4.0 |
27307295 |
acc2097 |
KNL1 |
phosphorylation |
Thr875 |
human |
breast cancer |
MDA-MB-231 |
paclitaxel |
inhibit |
5.0 |
31575759 |
acc2098 |
KNL1 |
phosphorylation |
Thr875 |
human |
breast cancer |
MDA-MB-468 |
paclitaxel |
inhibit |
5.0 |
31575759 |
acc2099 |
KNL1 |
phosphorylation |
Thr875 |
human |
breast cancer |
MDA-MB-231 |
BOS172722 |
modulate |
4.0 |
31575759 |
acc2100 |
KNL1 |
phosphorylation |
Thr875 |
human |
breast cancer |
MDA-MB-468 |
BOS172722 |
modulate |
4.0 |
31575759 |
acc2101 |
histone H3 |
phosphorylation |
Ser10 |
human |
breast cancer |
MDA-MB-231 |
BOS172722 |
modulate |
3.0 |
31575759 |
acc2102 |
histone H3 |
phosphorylation |
Ser10 |
human |
breast cancer |
MDA-MB-468 |
BOS172722 |
modulate |
3.0 |
31575759 |
acc2103 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
BT474 |
trastuzumab |
modulate |
4.0 |
21498638 |
acc2104 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
SK-BR-3 |
trastuzumab |
modulate |
4.0 |
21498638 |
acc2105 |
4EBP1 |
phosphorylation |
Ser65 |
human |
colon cancer |
HCT-8 |
cetuximab |
modulate |
4.0 |
21498638 |
acc2106 |
4EBP1 |
phosphorylation |
Ser65 |
human |
colon cancer |
HCT116 |
cetuximab |
modulate |
4.0 |
21498638 |
acc2107 |
4EBP1 |
phosphorylation |
Ser65 |
human |
head and neck cancer |
CAL33 |
erlotinib |
modulate |
4.0 |
21498638 |
acc2108 |
4EBP1 |
phosphorylation |
Ser65 |
human |
head and neck cancer |
CAL33-LTE |
erlotinib |
modulate |
4.0 |
21498638 |
acc2109 |
MYC |
phosphorylation |
Thr58 |
human |
prostate cancer |
PC3 |
anti-PD1 immunotherapy |
sensitize |
4.5 |
31679823 |
acc2110 |
MYC |
phosphorylation |
Thr58 |
human |
prostate cancer |
MycCaP |
anti-PD1 immunotherapy |
sensitize |
4.5 |
31679823 |
acc2111 |
MYC |
phosphorylation |
Thr58 |
human |
prostate cancer |
LNCaP |
anti-PD1 immunotherapy |
sensitize |
4.5 |
31679823 |
acc2112 |
STAT3 |
phosphorylation |
Ser727 |
human |
lung cancer |
A549 |
Cisplatin |
resist |
5.0 |
34543857 |
acc2113 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
A549 |
ACHP |
modulate |
4.0 |
31847229 |
acc2114 |
STAT3 |
phosphorylation |
Tyr705 |
human |
lung cancer |
H1299 |
ACHP |
modulate |
4.0 |
31847229 |
acc2115 |
STAT3 |
phosphorylation |
Tyr705 |
human |
cervical cancer |
HeLa |
resveratrol |
modulate |
4.0 |
33040485 |
acc2116 |
STAT3 |
phosphorylation |
Tyr705 |
human |
cervical cancer |
SiHa |
resveratrol |
modulate |
4.0 |
33040485 |
acc2117 |
p21WAF1/CIP2 |
phosphorylation |
Ser146 |
human |
hepatocellular carcinoma |
HepG2 |
asiatic acid |
modulate |
4.0 |
24568526 |
acc2118 |
p27 |
phosphorylation |
Ser10 |
human |
breast cancer |
BT474 |
erlotinib |
resist |
5.0 |
21045138 |
acc2119 |
p27 |
phosphorylation |
Ser10 |
human |
breast cancer |
SK-BR-3 |
erlotinib |
resist |
5.0 |
21045138 |
acc2120 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
breast cancer |
MDA-MB-435 |
Taxol |
inhibit |
5.0 |
12384528 |
acc2121 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
breast cancer |
SK-BR-3 |
Taxol |
inhibit |
5.0 |
12384528 |
acc2122 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
breast cancer |
MDA-MB-453 |
Taxol |
inhibit |
5.0 |
12384528 |
acc2123 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
breast cancer |
435eB |
Taxol |
inhibit |
5.0 |
12384528 |
acc2124 |
p36 |
phosphorylation |
unclear |
mouse |
lung cancer |
|
Butylated hydroxytoluene (BHT) |
inhibit |
5.0 |
4053047 |
acc2125 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
MCF7 |
SB203580 |
enhance |
5.0 |
11060298 |
acc2126 |
p38 |
phosphorylation |
Thr180 |
human |
leukemia |
NB-4 |
SB203580 |
enhance |
5.0 |
11060298 |
acc2127 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
MCF7 |
SB202190 |
enhance |
5.0 |
11060298 |
acc2128 |
p38 |
phosphorylation |
Thr180 |
human |
leukemia |
NB-4 |
SB202190 |
enhance |
5.0 |
11060298 |
acc2129 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
MCF7 |
SB203580 |
enhance |
5.0 |
11060298 |
acc2130 |
p38 |
phosphorylation |
Tyr182 |
human |
leukemia |
NB-4 |
SB203580 |
enhance |
5.0 |
11060298 |
acc2131 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
MCF7 |
SB202190 |
enhance |
5.0 |
11060298 |
acc2132 |
p38 |
phosphorylation |
Tyr182 |
human |
leukemia |
NB-4 |
SB202190 |
enhance |
5.0 |
11060298 |
acc2133 |
p38 |
phosphorylation |
Thr180 |
human |
colorectal cancer |
RKO |
melatonin |
modulate |
4.0 |
29152648 |
acc2134 |
p38 |
phosphorylation |
Tyr182 |
human |
colorectal cancer |
RKO |
melatonin |
modulate |
4.0 |
29152648 |
acc2135 |
p53 |
phosphorylation |
Ser392 |
human |
lung cancer |
HCC-827 |
MX-C4 |
modulate |
4.0 |
35902040 |
acc2136 |
p53 |
phosphorylation |
Ser392 |
human |
lung cancer |
HCI-H460 |
MX-C4 |
modulate |
4.0 |
35902040 |
acc2137 |
p53 |
phosphorylation |
Ser46 |
human |
colorectal cancer |
RKO |
adryamicin |
reduce |
5.0 |
25260780 |
acc2138 |
p53 |
phosphorylation |
Ser46 |
human |
colorectal cancer |
HCT116 |
adryamicin |
reduce |
5.0 |
25260780 |
acc2139 |
p53 |
phosphorylation |
Ser46 |
human |
ovarian cancer |
2008 |
adryamicin |
reduce |
5.0 |
25260780 |
acc2140 |
p53 |
phosphorylation |
Ser46 |
human |
lung cancer |
A549 |
adryamicin |
reduce |
5.0 |
25260780 |
acc2141 |
p53 |
phosphorylation |
Ser46 |
human |
colorectal cancer |
RKO |
Cisplatin |
reduce |
5.0 |
25260780 |
acc2142 |
p53 |
phosphorylation |
Ser46 |
human |
colorectal cancer |
HCT116 |
Cisplatin |
reduce |
5.0 |
25260780 |
acc2143 |
p53 |
phosphorylation |
Ser46 |
human |
ovarian cancer |
2008 |
Cisplatin |
reduce |
5.0 |
25260780 |
acc2144 |
p53 |
phosphorylation |
Ser46 |
human |
lung cancer |
A549 |
Cisplatin |
reduce |
5.0 |
25260780 |
acc2145 |
p53 |
phosphorylation |
Ser20 |
human |
colorectal cancer |
HCT116 |
ionizing radiation |
inhibit |
4.5 |
12384533 |
acc2146 |
p53 |
phosphorylation |
Ser15 |
human |
colorectal cancer |
HCT116 |
NO + ionizing radiation |
enhance |
4.5 |
15520210 |
acc2147 |
p53 |
phosphorylation |
Ser15 |
human |
gastric cancer |
SNU-1040 |
NO + ionizing radiation |
enhance |
4.5 |
15520210 |
acc2148 |
p53 |
phosphorylation |
Ser15 |
human |
ovarian cancer |
A2780 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2149 |
p53 |
phosphorylation |
Ser15 |
human |
breast cancer |
MCF7 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2150 |
p53 |
phosphorylation |
Ser392 |
human |
ovarian cancer |
A2780 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2151 |
p53 |
phosphorylation |
Ser392 |
human |
breast cancer |
MCF7 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2152 |
p53 |
phosphorylation |
Ser15 |
human |
ovarian cancer |
2780CP/Cl-16 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2153 |
p53 |
phosphorylation |
Ser15 |
human |
ovarian cancer |
HEY/C-2 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2154 |
p53 |
phosphorylation |
Ser392 |
human |
ovarian cancer |
2780CP/Cl-16 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2155 |
p53 |
phosphorylation |
Ser392 |
human |
ovarian cancer |
HEY/C-2 |
Cisplatin |
increase |
5.0 |
14513366 |
acc2156 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
PC9 |
osimertinib |
inhibit |
5.0 |
34599981 |
acc2157 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
PC9 |
osimertinib |
inhibit |
5.0 |
34599981 |
acc2158 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
PC9 |
osimertinib |
inhibit |
5.0 |
34599981 |
acc2159 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
PC9 |
osimertinib |
inhibit |
5.0 |
34599981 |
acc2160 |
PAX3-FOXO1 |
phosphorylation |
Ser201 |
human |
sarcoma |
Rh30 |
LiCl |
modulate |
4.0 |
25821947 |
acc2161 |
PAX3-FOXO1 |
phosphorylation |
Ser205 |
human |
sarcoma |
Rh30 |
LiCl |
modulate |
4.0 |
25821947 |
acc2162 |
PAX3-FOXO1 |
phosphorylation |
Ser201 |
human |
sarcoma |
RH4 |
LiCl |
modulate |
4.0 |
25821947 |
acc2163 |
PAX3-FOXO1 |
phosphorylation |
Ser205 |
human |
sarcoma |
RH4 |
LiCl |
modulate |
4.0 |
25821947 |
acc2164 |
PAX3-FOXO1 |
phosphorylation |
Ser201 |
human |
sarcoma |
Rh30 |
AR-A014418 |
modulate |
4.0 |
25821947 |
acc2165 |
PAX3-FOXO1 |
phosphorylation |
Ser205 |
human |
sarcoma |
Rh30 |
AR-A014418 |
modulate |
4.0 |
25821947 |
acc2166 |
PAX3-FOXO1 |
phosphorylation |
Ser201 |
human |
sarcoma |
RH4 |
AR-A014418 |
modulate |
4.0 |
25821947 |
acc2167 |
PAX3-FOXO1 |
phosphorylation |
Ser205 |
human |
sarcoma |
RH4 |
AR-A014418 |
modulate |
4.0 |
25821947 |
acc2168 |
PCK1 |
phosphorylation |
Ser90 |
human |
hepatocellular carcinoma |
HuH-7 |
MK-220 |
modulate |
4.0 |
32322062 |
acc2169 |
PCK1 |
phosphorylation |
Ser90 |
human |
hepatocellular carcinoma |
Hep3B |
MK-220 |
modulate |
4.0 |
32322062 |
acc2170 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
MCF7 |
etoposide |
increase |
5.0 |
24786831 |
acc2171 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
ZR75 |
etoposide |
increase |
5.0 |
24786831 |
acc2172 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
MCF7 |
camptothecin |
increase |
5.0 |
24786831 |
acc2173 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
ZR75 |
camptothecin |
increase |
5.0 |
24786831 |
acc2174 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
MCF7 |
gamma-radiation |
increase |
4.5 |
24786831 |
acc2175 |
PELP1 |
phosphorylation |
Ser1033 |
human |
breast cancer |
ZR75 |
gamma-radiation |
increase |
4.5 |
24786831 |
acc2176 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
leukemia |
K562 |
imatinib |
sensitize |
5.0 |
23095523 |
acc2177 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
leukemia |
BV173 |
imatinib |
sensitize |
5.0 |
23095523 |
acc2178 |
PTEN |
phosphorylation |
Tyr240 |
human |
glioma |
patient-derivedglioma stem celllines |
ionizing radiation |
resist |
4.5 |
31025173 |
acc2179 |
AMPKalpha1 |
phosphorylation |
Thr467 |
human |
cervical cancer |
Ishikawa |
SMI-4a + AICAR |
modulate |
4.0 |
31358902 |
acc2180 |
PKC |
phosphorylation |
Ser660 |
human |
prostate cancer |
LNCaP |
Ro-31-8220(PKC inhibitor) |
sensitize |
5.0 |
24352647 |
acc2181 |
PKC |
phosphorylation |
Ser660 |
human |
prostate cancer |
C4-2 |
Ro-31-8220(PKC inhibitor) |
sensitize |
5.0 |
24352647 |
acc2182 |
PKC |
phosphorylation |
Ser660 |
human |
prostate cancer |
22Rv1 |
Ro-31-8220(PKC inhibitor) |
sensitize |
5.0 |
24352647 |
acc2183 |
Hsp27 |
phosphorylation |
Ser15 |
human |
leukemia |
THP-1 |
apigenin |
increase |
5.0 |
21364669 |
acc2184 |
Hsp27 |
phosphorylation |
Ser78 |
human |
leukemia |
THP-1 |
apigenin |
increase |
5.0 |
21364669 |
acc2185 |
Hsp27 |
phosphorylation |
Ser82 |
human |
leukemia |
THP-1 |
apigenin |
increase |
5.0 |
21364669 |
acc2186 |
STAT1 |
phosphorylation |
Ser727 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2187 |
STAT1 |
phosphorylation |
Tyr701 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2188 |
JAK-1 |
phosphorylation |
Tyr1022 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2189 |
JAK-1 |
phosphorylation |
Tyr1023 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2190 |
JAK-2 |
phosphorylation |
Tyr1007 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2191 |
JAK-2 |
phosphorylation |
Tyr1008 |
human |
oral cancer |
HSC-3 |
EGCG |
modulate |
4.0 |
19928918 |
acc2192 |
PKCdelta |
phosphorylation |
Thr507 |
human |
colorectal cancer |
HT29 |
magnolol |
modulate |
4.0 |
32429376 |
acc2193 |
PKCdelta |
phosphorylation |
Thr507 |
human |
colorectal cancer |
CT26 |
magnolol |
modulate |
4.0 |
32429376 |
acc2194 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT29 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2195 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
CT26 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2196 |
NF-kappaB |
phosphorylation |
Ser276 |
human |
colorectal cancer |
HT29 |
magnolol |
modulate |
4.0 |
32429376 |
acc2197 |
NF-kappaB |
phosphorylation |
Ser276 |
human |
colorectal cancer |
CT26 |
magnolol |
modulate |
4.0 |
32429376 |
acc2198 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT29 |
magnolol |
modulate |
4.0 |
32429376 |
acc2199 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
CT26 |
magnolol |
modulate |
4.0 |
32429376 |
acc2200 |
PKCdelta |
phosphorylation |
Thr507 |
human |
colorectal cancer |
HT29 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2201 |
PKCdelta |
phosphorylation |
Thr507 |
human |
colorectal cancer |
CT26 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2202 |
NF-kappaB |
phosphorylation |
Ser276 |
human |
colorectal cancer |
HT29 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2203 |
NF-kappaB |
phosphorylation |
Ser276 |
human |
colorectal cancer |
CT26 |
rottlerin |
modulate |
4.0 |
32429376 |
acc2204 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MCF7 |
VPA |
modulate |
4.0 |
34263655 |
acc2205 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MDA-MB-231 |
VPA |
modulate |
4.0 |
34263655 |
acc2206 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF7 |
VPA |
modulate |
4.0 |
34263655 |
acc2207 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MDA-MB-231 |
VPA |
modulate |
4.0 |
34263655 |
acc2208 |
PLK1 |
phosphorylation |
Thr210 |
human |
prostate cancer |
PC3 |
KUD773 |
increase |
5.0 |
25563361 |
acc2209 |
PLK1 |
phosphorylation |
Thr210 |
human |
prostate cancer |
DU145 |
KUD773 |
increase |
5.0 |
25563361 |
acc2210 |
pp125FAK |
phosphorylation |
Tyr |
human |
prostate cancer |
PC3 |
bombesin |
modulate |
4.0 |
9247295 |
acc2211 |
Akt |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-468 |
tamoxifen |
modulate |
4.0 |
29261144 |
acc2212 |
Akt |
phosphorylation |
Ser473 |
human |
breast cancer |
HCC-1937 |
tamoxifen |
modulate |
4.0 |
29261144 |
acc2213 |
PRAS40 |
phosphorylation |
Thr246 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2214 |
PRAS40 |
phosphorylation |
Thr246 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2215 |
AKT |
phosphorylation |
Thr308 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2216 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2217 |
4EBP1 |
phosphorylation |
Ser65 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2218 |
4EBP1 |
phosphorylation |
Ser65 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2219 |
GSK3beta |
phosphorylation |
Ser9 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2220 |
GSK3beta |
phosphorylation |
Ser9 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2221 |
S6 |
phosphorylation |
Ser235 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2222 |
S6 |
phosphorylation |
Ser235 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2223 |
S6 |
phosphorylation |
Ser236 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2224 |
S6 |
phosphorylation |
Ser236 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2225 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
LNCaP |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2226 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
BT474c |
AZD5363 |
modulate |
4.0 |
22294718 |
acc2227 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
OE19 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2228 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
OE19 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2229 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
TE-13 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2230 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
TE-13 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2231 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
OE21 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2232 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
OE21 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2233 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
TE-13 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2234 |
RB |
phosphorylation |
Ser807 |
human |
esophageal cancer |
TE-13 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2235 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
OE19 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2236 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
OE19 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2237 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
OE21 |
5-FU |
inhibit |
5.0 |
28734226 |
acc2238 |
RB |
phosphorylation |
Ser811 |
human |
esophageal cancer |
OE21 |
Cisplatin |
increase |
5.0 |
28734226 |
acc2239 |
AXL |
phosphorylation |
Tyr702 |
human |
glioblastoma |
|
nivolumab |
inhibit |
5.0 |
29531161 |
acc2240 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
hepatocellular carcinoma |
HA22T |
apicidin |
enhance |
5.0 |
31261976 |
acc2241 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
hepatocellular carcinoma |
HA22T |
SAHA |
inhibit |
5.0 |
31261976 |
acc2242 |
CHK1 |
phosphorylation |
Ser317 |
human |
lung cancer |
HTB182 |
Cisplatin |
decrease |
5.0 |
25937999 |
acc2243 |
CHK1 |
phosphorylation |
Ser345 |
human |
lung cancer |
HTB182 |
Cisplatin |
decrease |
5.0 |
25937999 |
acc2244 |
ATM |
phosphorylation |
Ser1981 |
human |
lung cancer |
HTB182 |
Cisplatin |
increase |
5.0 |
25937999 |
acc2245 |
CHK1 |
phosphorylation |
Ser317 |
human |
lung cancer |
CRL5985 |
Cisplatin |
decrease |
5.0 |
25937999 |
acc2246 |
CHK1 |
phosphorylation |
Ser345 |
human |
lung cancer |
CRL5985 |
Cisplatin |
decrease |
5.0 |
25937999 |
acc2247 |
ATM |
phosphorylation |
Ser1981 |
human |
lung cancer |
CRL5985 |
Cisplatin |
increase |
5.0 |
25937999 |
acc2248 |
RB1 |
phosphorylation |
Thr356 |
human |
head and neck cancer |
FaDu |
palbociclib(CDK4/6 inhibitors) |
modulate |
4.0 |
26265441 |
acc2249 |
RB1 |
phosphorylation |
Thr356 |
human |
head and neck cancer |
SCC61 |
palbociclib(CDK4/6 inhibitors) |
modulate |
4.0 |
26265441 |
acc2250 |
RelA |
phosphorylation |
Ser536 |
human |
breast cancer |
MCF7 |
RITA |
increase |
5.0 |
27721021 |
acc2251 |
RelA |
phosphorylation |
Ser276 |
human |
breast cancer |
MCF7 |
RITA |
resist |
5.0 |
27721021 |
acc2252 |
RelA |
phosphorylation |
Ser468 |
human |
breast cancer |
MCF7 |
RITA |
resist |
5.0 |
27721021 |
acc2253 |
RelA |
phosphorylation |
Ser536 |
human |
colorectal cancer |
HCT116 |
RITA |
increase |
5.0 |
27721021 |
acc2254 |
RelA |
phosphorylation |
Ser276 |
human |
colorectal cancer |
HCT116 |
RITA |
resist |
5.0 |
27721021 |
acc2255 |
RelA |
phosphorylation |
Ser468 |
human |
colorectal cancer |
HCT116 |
RITA |
resist |
5.0 |
27721021 |
acc2256 |
Erk1 |
phosphorylation |
Thr202 |
human |
sarcoma |
Rh1 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2257 |
Erk1 |
phosphorylation |
Tyr204 |
human |
sarcoma |
Rh1 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2258 |
Erk2 |
phosphorylation |
Thr185 |
human |
colon cancer |
HT29 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2259 |
Erk2 |
phosphorylation |
Tyr187 |
human |
colon cancer |
HT29 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2260 |
Erk1 |
phosphorylation |
Thr202 |
human |
cervical cancer |
HeLa |
resveratrol |
modulate |
3.0 |
30066962 |
acc2261 |
Erk1 |
phosphorylation |
Tyr204 |
human |
cervical cancer |
HeLa |
resveratrol |
modulate |
3.0 |
30066962 |
acc2262 |
Erk2 |
phosphorylation |
Thr185 |
human |
cervical cancer |
HeLa |
resveratrol |
modulate |
3.0 |
30066962 |
acc2263 |
Erk2 |
phosphorylation |
Tyr187 |
human |
cervical cancer |
HeLa |
resveratrol |
modulate |
3.0 |
30066962 |
acc2264 |
Erk2 |
phosphorylation |
Thr185 |
human |
sarcoma |
Rh1 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2265 |
Erk2 |
phosphorylation |
Tyr187 |
human |
sarcoma |
Rh1 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2266 |
Erk1 |
phosphorylation |
Thr202 |
human |
sarcoma |
Rh30 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2267 |
Erk1 |
phosphorylation |
Tyr204 |
human |
sarcoma |
Rh30 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2268 |
Erk2 |
phosphorylation |
Thr185 |
human |
sarcoma |
Rh30 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2269 |
Erk2 |
phosphorylation |
Tyr187 |
human |
sarcoma |
Rh30 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2270 |
Erk1 |
phosphorylation |
Thr202 |
human |
colon cancer |
HT29 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2271 |
Erk1 |
phosphorylation |
Tyr204 |
human |
colon cancer |
HT29 |
resveratrol |
modulate |
3.0 |
30066962 |
acc2272 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
SK-BR-3 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2273 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
SK-BR-3 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2274 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
HCC1954 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2275 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
HCC1954 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2276 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
SK-BR-3 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2277 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
SK-BR-3 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2278 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
HCC1954 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2279 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
HCC1954 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2280 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
SK-BR-3 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2281 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
SK-BR-3 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2282 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
HCC1954 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2283 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
HCC1954 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2284 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
HCC1954 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2285 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
SK-BR-3 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2286 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
SK-BR-3 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2287 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
HCC1954 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2288 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
HCC1954 |
erlotinib + trastuzumab |
modulate |
4.0 |
23552733 |
acc2289 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
HCC1954 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2290 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
SK-BR-3 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2291 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
SK-BR-3 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2292 |
RB |
phosphorylation |
Ser807 |
human |
breast cancer |
HCC1954 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2293 |
RB |
phosphorylation |
Ser811 |
human |
breast cancer |
HCC1954 |
erlotinib |
modulate |
4.0 |
23552733 |
acc2294 |
RPS6 |
phosphorylation |
Ser235 |
human |
breast cancer |
SK-BR-3 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2295 |
RPS6 |
phosphorylation |
Ser236 |
human |
breast cancer |
SK-BR-3 |
erlotinib + pertuzumab |
modulate |
4.0 |
23552733 |
acc2296 |
IRAK1 |
phosphorylation |
unclear |
human |
nasopharyngeal carcinoma |
CNE2 R |
paclitaxel |
sensitize |
5.0 |
33402387 |
acc2297 |
IRAK1 |
phosphorylation |
unclear |
human |
nasopharyngeal carcinoma |
S26 R |
paclitaxel |
sensitize |
5.0 |
33402387 |
acc2298 |
NDRG-1 |
phosphorylation |
Thr346 |
human |
myeloma |
BR bortezomib-resistant 8226 |
bortezomib |
resist |
5.0 |
26869290 |
acc2299 |
STAT3 |
phosphorylation |
Tyr705 |
human |
colon cancer |
HCT116 |
celastrol derivative 4m |
modulate |
4.0 |
34894961 |
acc2300 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
A375 |
FLLL32 |
modulate |
4.0 |
20576164 |
acc2301 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
Hs294T |
FLLL32 |
modulate |
4.0 |
20576164 |
acc2302 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
pimozide |
modulate |
4.0 |
26549437 |
acc2303 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
LNCaP |
pimozide |
modulate |
4.0 |
26549437 |
acc2304 |
Src |
phosphorylation |
Tyr416 |
human |
lung cancer |
FA31 |
gefitinib |
resist |
5.0 |
19491201 |
acc2305 |
Src |
phosphorylation |
Tyr416 |
human |
lung cancer |
H1819 |
gefitinib |
resist |
5.0 |
19491201 |
acc2306 |
Src |
phosphorylation |
Tyr416 |
human |
lung cancer |
H1975 |
gefitinib |
resist |
5.0 |
19491201 |
acc2307 |
Neu |
phosphorylation |
Tyr1201 |
human |
breast cancer |
MCF7 |
heregulin |
modulate |
4.0 |
19525980 |
acc2308 |
Neu |
phosphorylation |
Tyr1226 |
human |
breast cancer |
MCF7 |
heregulin |
modulate |
4.0 |
19525980 |
acc2309 |
Neu |
phosphorylation |
Tyr1227 |
human |
breast cancer |
MCF7 |
heregulin |
modulate |
4.0 |
19525980 |
acc2310 |
Neu |
phosphorylation |
Tyr1201 |
human |
breast cancer |
T47D |
heregulin |
modulate |
4.0 |
19525980 |
acc2311 |
Neu |
phosphorylation |
Tyr1226 |
human |
breast cancer |
T47D |
heregulin |
modulate |
4.0 |
19525980 |
acc2312 |
Neu |
phosphorylation |
Tyr1227 |
human |
breast cancer |
T47D |
heregulin |
modulate |
4.0 |
19525980 |
acc2313 |
Neu |
phosphorylation |
Tyr1201 |
mouse |
breast cancer |
4T1 |
heregulin |
modulate |
4.0 |
19525980 |
acc2314 |
Neu |
phosphorylation |
Tyr1226 |
mouse |
breast cancer |
4T1 |
heregulin |
modulate |
4.0 |
19525980 |
acc2315 |
Neu |
phosphorylation |
Tyr1227 |
mouse |
breast cancer |
4T1 |
heregulin |
modulate |
4.0 |
19525980 |
acc2316 |
SMAD2 |
phosphorylation |
Ser465 |
human |
hepatocellular carcinoma |
HepG2 |
NH4Cl |
promote |
5.0 |
25342595 |
acc2317 |
SMAD2 |
phosphorylation |
Ser467 |
human |
hepatocellular carcinoma |
HepG2 |
NH4Cl |
promote |
5.0 |
25342595 |
acc2318 |
CtIP |
phosphorylation |
Thr847 |
human |
ovarian cancer |
IGROV1 |
olaparib |
promote |
5.0 |
37333340 |
acc2319 |
CtIP |
phosphorylation |
Thr847 |
human |
ovarian cancer |
IGROV1 |
Cisplatin |
promote |
5.0 |
37333340 |
acc2320 |
Tau |
phosphorylation |
Thr205 |
human |
neuroblastoma |
SH-SY5Y |
ebselen |
modulate |
3.0 |
22634399 |
acc2321 |
Tau |
phosphorylation |
Ser396 |
human |
neuroblastoma |
SH-SY5Y |
ebselen |
modulate |
3.0 |
22634399 |
acc2322 |
Tau |
phosphorylation |
Thr231 |
human |
neuroblastoma |
SH-SY5Y |
ebselen |
modulate |
3.0 |
22634399 |
acc2323 |
Smad2 |
phosphorylation |
Ser465 |
human |
breast cancer |
MCF7 |
SSA |
modulate |
4.0 |
26769851 |
acc2324 |
Smad2 |
phosphorylation |
Ser467 |
human |
breast cancer |
MCF7 |
SSA |
modulate |
4.0 |
26769851 |
acc2325 |
Smad3 |
phosphorylation |
Ser423 |
human |
breast cancer |
MCF7 |
SSA |
modulate |
4.0 |
26769851 |
acc2326 |
Smad3 |
phosphorylation |
Ser425 |
human |
breast cancer |
MCF7 |
SSA |
modulate |
4.0 |
26769851 |
acc2327 |
Smad2 |
phosphorylation |
Ser465 |
human |
breast cancer |
MDA-MB-231 |
SSA |
modulate |
4.0 |
26769851 |
acc2328 |
Smad2 |
phosphorylation |
Ser467 |
human |
breast cancer |
MDA-MB-231 |
SSA |
modulate |
4.0 |
26769851 |
acc2329 |
Smad3 |
phosphorylation |
Ser423 |
human |
breast cancer |
MDA-MB-231 |
SSA |
modulate |
4.0 |
26769851 |
acc2330 |
Smad3 |
phosphorylation |
Ser425 |
human |
breast cancer |
MDA-MB-231 |
SSA |
modulate |
4.0 |
26769851 |
acc2331 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
A375 |
Gentian violet(GV) |
modulate |
4.0 |
27373978 |
acc2332 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
SSM2c |
Gentian violet(GV) |
modulate |
4.0 |
27373978 |
acc2333 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
M33x |
Gentian violet(GV) |
modulate |
4.0 |
27373978 |
acc2334 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
Niclosamide |
modulate |
4.0 |
33002501 |
acc2335 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
MCF7 |
Niclosamide |
modulate |
4.0 |
33002501 |
acc2336 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
Stattic |
modulate |
4.0 |
33002501 |
acc2337 |
STAT3 |
phosphorylation |
Tyr705 |
human |
myeloma |
ARH-77 |
LLL12 |
modulate |
4.0 |
21520044 |
acc2338 |
STAT3 |
phosphorylation |
Tyr705 |
human |
myeloma |
U266 |
lenalidomide |
inhibit |
5.0 |
21520044 |
acc2339 |
STAT3 |
phosphorylation |
Tyr705 |
human |
myeloma |
MM1.S |
lenalidomide |
inhibit |
5.0 |
21520044 |
acc2340 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HepG2 |
XZH-5 |
modulate |
4.0 |
21311975 |
acc2341 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HuH-7 |
XZH-5 |
modulate |
4.0 |
21311975 |
acc2342 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-387 |
XZH-5 |
modulate |
4.0 |
21311975 |
acc2343 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-398 |
XZH-5 |
modulate |
4.0 |
21311975 |
acc2344 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-468 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2345 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MDA-MB-468 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2346 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2347 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2348 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
MDA-MB-468 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2349 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
MDA-MB-468 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2350 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
BT549 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2351 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
BT549 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2352 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
MCF7 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2353 |
STAT3 |
phosphorylation |
Ser727 |
human |
breast cancer |
MCF7 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2354 |
STAT3 |
phosphorylation |
Ser727 |
human |
ovarian cancer |
OVCAR8 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2355 |
STAT3 |
phosphorylation |
Ser727 |
human |
ovarian cancer |
OVCAR8 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2356 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
BT549 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2357 |
STAT3 |
phosphorylation |
Ser727 |
human |
ovarian cancer |
SK-OV-3 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2358 |
STAT3 |
phosphorylation |
Ser727 |
human |
ovarian cancer |
SK-OV-3 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2359 |
STAT3 |
phosphorylation |
Ser727 |
human |
prostate cancer |
DU145 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2360 |
STAT3 |
phosphorylation |
Ser727 |
human |
prostate cancer |
DU145 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2361 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
BT549 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2362 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2363 |
STAT3 |
phosphorylation |
Tyr705 |
human |
breast cancer |
MCF7 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2364 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR8 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2365 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR8 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2366 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
SK-OV-3 |
vinorelbine |
modulate |
4.0 |
20693278 |
acc2367 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
SK-OV-3 |
paclitaxel |
modulate |
4.0 |
20693278 |
acc2368 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
HepG2 |
Bazedoxifene(BAZ) |
modulate |
4.0 |
30648776 |
acc2369 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
SSMC-7721 |
Bazedoxifene(BAZ) |
modulate |
4.0 |
30648776 |
acc2370 |
STAT3 |
phosphorylation |
Tyr705 |
human |
liver cancer |
HuH-7 |
Bazedoxifene(BAZ) |
modulate |
4.0 |
30648776 |
acc2371 |
STAT3 |
phosphorylation |
Ser727 |
human |
prostate cancer |
DU145 |
scoparone |
modulate |
4.0 |
24260381 |
acc2372 |
STAT3 |
phosphorylation |
Tyr705 |
human |
prostate cancer |
DU145 |
scoparone |
modulate |
4.0 |
24260381 |
acc2373 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
SK-OV-3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2374 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
SK-OV-3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2375 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
CAOV3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2376 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
CAOV3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2377 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OVCAR-3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2378 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
OVCAR-3 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2379 |
STAT3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
OV75 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2380 |
AKT |
phosphorylation |
Ser473 |
human |
ovarian cancer |
OV75 |
bazedoxifene(Baze) + SCH527123(SCH) |
modulate |
4.0 |
35315502 |
acc2381 |
Stat3 |
phosphorylation |
Tyr705 |
human |
ovarian cancer |
SK-OV-3TR(paclitaxel-res) |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc2382 |
Jak2 |
phosphorylation |
Tyr1007 |
human |
ovarian cancer |
SK-OV-3TR(paclitaxel-res) |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc2383 |
Jak2 |
phosphorylation |
Tyr1008 |
human |
ovarian cancer |
SK-OV-3TR(paclitaxel-res) |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc2384 |
Src |
phosphorylation |
Tyr530 |
human |
ovarian cancer |
SK-OV-3TR(paclitaxel-res) |
CDDO-Me |
modulate |
4.0 |
18587580 |
acc2385 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
K562 |
Cryptotanshinone |
modulate |
4.0 |
30054832 |
acc2386 |
STAT5 |
phosphorylation |
Tyr694 |
human |
leukemia |
|
Cryptotanshinone |
modulate |
4.0 |
30054832 |
acc2387 |
STAT5 |
phosphorylation |
Tyr694 |
human |
leukemia |
|
Imatinib mesylate |
modulate |
4.0 |
28387753 |
acc2388 |
STAT5 |
phosphorylation |
Tyr694 |
human |
breast cancer |
HC11-Cuzd1 |
pimozide |
modulate |
4.0 |
29321207 |
acc2389 |
STAT5 |
phosphorylation |
Tyr694 |
human |
breast cancer |
MCF7-Cuzd1 |
pimozide |
modulate |
4.0 |
29321207 |
acc2390 |
STAT5 |
phosphorylation |
Tyr694 |
human |
lymphoma |
CRL-2105 |
romidepsin |
inhibit |
5.0 |
34089720 |
acc2391 |
STAT5 |
phosphorylation |
Tyr694 |
human |
lymphoma |
HuT78 |
romidepsin |
inhibit |
5.0 |
34089720 |
acc2392 |
STAT5 |
phosphorylation |
Tyr694 |
human |
hepatocellular carcinoma |
|
PD-1 therapy |
inhibit |
4.5 |
34036623 |
acc2393 |
STAT6 |
phosphorylation |
Tyr641 |
mouse |
breast cancer |
4T1 |
emodin |
modulate |
4.0 |
25311112 |
acc2394 |
STAT6 |
phosphorylation |
Tyr641 |
human |
breast cancer |
EO771 |
emodin |
modulate |
4.0 |
25311112 |
acc2395 |
H2AX |
methylation |
Lys134 |
human |
breast cancer |
MDA-MB-231 |
doxorubicin |
inhibit |
4.0 |
30159125 |
acc2396 |
H2AX |
phosphorylation |
Ser139 |
human |
breast cancer |
MDA-MB-231 |
doxorubicin |
inhibit |
4.0 |
30159125 |
acc2397 |
H2AX |
methylation |
Lys134 |
human |
lung cancer |
A549 |
doxorubicin |
inhibit |
4.0 |
30159125 |
acc2398 |
H2AX |
phosphorylation |
Ser139 |
human |
lung cancer |
A549 |
doxorubicin |
inhibit |
4.0 |
30159125 |
acc2399 |
H2AX |
methylation |
Lys134 |
human |
breast cancer |
MDA-MB-231 |
OTS193320 |
modulate |
3.0 |
30159125 |
acc2400 |
H2AX |
phosphorylation |
Ser139 |
human |
breast cancer |
MDA-MB-231 |
OTS193320 |
modulate |
3.0 |
30159125 |
acc2401 |
H2AX |
methylation |
Lys134 |
human |
lung cancer |
A549 |
OTS193320 |
modulate |
3.0 |
30159125 |
acc2402 |
H2AX |
phosphorylation |
Ser139 |
human |
lung cancer |
A549 |
OTS193320 |
modulate |
3.0 |
30159125 |
acc2403 |
YAP |
phosphorylation |
Ser127 |
human |
pancreas cancer |
PANC-1 |
gemcitabine |
decrease |
5.0 |
31627466 |
acc2404 |
YAP |
phosphorylation |
Ser127 |
human |
pancreas cancer |
BxPC-3 |
gemcitabine |
decrease |
5.0 |
31627466 |
acc2405 |
YAP |
phosphorylation |
Ser127 |
human |
pancreas cancer |
ASPC-1 |
gemcitabine |
decrease |
5.0 |
31627466 |
acc2406 |
BCL2 |
phosphorylation |
unclear |
human |
lung cancer |
H5800 |
Cisplatin |
increase |
5.0 |
24548862 |
acc2407 |
BCL2 |
phosphorylation |
unclear |
mouse |
lung cancer |
LKR |
Cisplatin |
increase |
5.0 |
24548862 |
acc2408 |
Beclin-1 |
ubiquitination |
Ser90 |
human |
myeloma |
KMS11 |
BTZ |
decrease |
5.0 |
31955515 |
acc2409 |
Beclin-1 |
ubiquitination |
Ser90 |
human |
myeloma |
RPMI8226 |
BTZ |
decrease |
5.0 |
31955515 |
acc2410 |
Beclin-1 |
ubiquitination |
Ser93 |
human |
myeloma |
KMS11 |
BTZ |
decrease |
5.0 |
31955515 |
acc2411 |
Beclin-1 |
ubiquitination |
Ser93 |
human |
myeloma |
RPMI8226 |
BTZ |
decrease |
5.0 |
31955515 |
acc2412 |
Beclin-1 |
ubiquitination |
Ser96 |
human |
myeloma |
KMS11 |
BTZ |
decrease |
5.0 |
31955515 |
acc2413 |
Beclin-1 |
ubiquitination |
Ser96 |
human |
myeloma |
RPMI8226 |
BTZ |
decrease |
5.0 |
31955515 |
acc2414 |
MRE11 |
ubiquitination |
Lys339 |
human |
breast cancer |
HCC1806 |
radiotherapy |
improve |
5.0 |
36563124 |
acc2415 |
MRE11 |
ubiquitination |
Lys339 |
human |
breast cancer |
MDA-MB-231 |
radiotherapy |
improve |
5.0 |
36563124 |
acc2416 |
MRE11 |
ubiquitination |
Lys480 |
human |
breast cancer |
HCC1806 |
radiotherapy |
improve |
5.0 |
36563124 |
acc2417 |
MRE11 |
ubiquitination |
Lys480 |
human |
breast cancer |
MDA-MB-231 |
radiotherapy |
improve |
5.0 |
36563124 |
acc2418 |
RIPK1 |
ubiquitination |
unclear |
human |
leukemia |
MT4 |
birinapant |
modulate |
4.0 |
32024820 |
acc2419 |
CYLD |
phosphorylation |
Ser418 |
human |
leukemia |
MT4 |
birinapant |
modulate |
4.0 |
32024820 |
acc2420 |
RIPK1 |
ubiquitination |
unclear |
human |
leukemia |
MT4 |
MRT67307 |
modulate |
4.0 |
32024820 |
acc2421 |
CYLD |
phosphorylation |
Ser418 |
human |
leukemia |
MT4 |
MRT67307 |
modulate |
4.0 |
32024820 |
acc2422 |
RIPK1 |
ubiquitination |
unclear |
human |
leukemia |
MT4 |
TPCA |
modulate |
4.0 |
32024820 |
acc2423 |
CYLD |
phosphorylation |
Ser418 |
human |
leukemia |
MT4 |
TPCA |
modulate |
4.0 |
32024820 |
acc2424 |
ERK1 |
phosphorylation |
Thr202 |
human |
hepatocellular carcinoma |
Hep3B |
EGCG |
modulate |
4.0 |
19360302 |
acc2425 |
ERK1 |
phosphorylation |
Tyr204 |
human |
hepatocellular carcinoma |
Hep3B |
EGCG |
modulate |
4.0 |
19360302 |
acc2426 |
ERK2 |
phosphorylation |
Thr185 |
human |
hepatocellular carcinoma |
Hep3B |
EGCG |
modulate |
4.0 |
19360302 |
acc2427 |
ERK2 |
phosphorylation |
Tyr187 |
human |
hepatocellular carcinoma |
Hep3B |
EGCG |
modulate |
4.0 |
19360302 |
acc2428 |
NFKBIA |
phosphorylation |
Ser32 |
human |
myeloma |
MM.1S |
PS-1145 |
modulate |
4.0 |
11872748 |
acc2429 |
NFKBIA |
phosphorylation |
Ser32 |
human |
myeloma |
RPMI8226 |
PS-1145 |
modulate |
4.0 |
11872748 |
acc2430 |
NFKBIA |
phosphorylation |
Ser32 |
human |
myeloma |
U266 |
PS-1145 |
modulate |
4.0 |
11872748 |
acc2431 |
NFKBIA |
phosphorylation |
Ser32 |
human |
myeloma |
MM.1S |
PS-1145 + Dex |
modulate |
4.0 |
11872748 |
acc2432 |
TOPK |
phosphorylation |
Thr9 |
human |
melanoma |
RPMI7951 |
arsenite |
modulate |
4.0 |
17145805 |
acc2433 |
H2AX |
phosphorylation |
Ser139 |
human |
melanoma |
RPMI7951 |
arsenite |
modulate |
3.0 |
17145805 |
acc2434 |
AMPK |
phosphorylation |
Thr172 |
human |
lung cancer |
A549 |
TRAIL |
inhibit |
5.0 |
29929000 |
acc2435 |
AMPK |
phosphorylation |
Thr183 |
human |
lung cancer |
A549 |
TRAIL |
inhibit |
5.0 |
29929000 |
acc2436 |
AMPK |
phosphorylation |
Thr172 |
human |
lung cancer |
HCC-15 |
TRAIL |
inhibit |
5.0 |
29929000 |
acc2437 |
AMPK |
phosphorylation |
Thr183 |
human |
lung cancer |
HCC-15 |
TRAIL |
inhibit |
5.0 |
29929000 |
acc2438 |
JNK2 |
phosphorylation |
Thr183 |
human |
colorectal cancer |
HT29 |
TRAIL + 5-fluorouracil (7-FU) |
inhibit |
5.0 |
15837763 |
acc2439 |
JNK2 |
phosphorylation |
Thr183 |
human |
hepatocellular carcinoma |
HepG2 |
TRAIL + 5-fluorouracil (8-FU) |
inhibit |
5.0 |
15837763 |
acc2440 |
JNK2 |
phosphorylation |
Tyr185 |
human |
colorectal cancer |
HT29 |
TRAIL + 5-fluorouracil (9-FU) |
inhibit |
5.0 |
15837763 |
acc2441 |
JNK2 |
phosphorylation |
Tyr185 |
human |
hepatocellular carcinoma |
HepG2 |
TRAIL + 5-fluorouracil (10-FU) |
inhibit |
5.0 |
15837763 |
acc2442 |
JNK2 |
phosphorylation |
Thr183 |
human |
colorectal cancer |
HT29 |
TRAIL + cisplatin |
inhibit |
5.0 |
15837763 |
acc2443 |
JNK2 |
phosphorylation |
Thr183 |
human |
hepatocellular carcinoma |
HepG2 |
TRAIL + cisplatin |
inhibit |
5.0 |
15837763 |
acc2444 |
JNK2 |
phosphorylation |
Tyr185 |
human |
colorectal cancer |
HT29 |
TRAIL + cisplatin |
inhibit |
5.0 |
15837763 |
acc2445 |
JNK2 |
phosphorylation |
Tyr185 |
human |
hepatocellular carcinoma |
HepG2 |
TRAIL + cisplatin |
inhibit |
5.0 |
15837763 |
acc2446 |
TRIP13 |
phosphorylation |
Tyr56 |
human |
head and neck cancer |
UM-SCC-1 |
cetuximab |
sensitize |
5.0 |
34111559 |
acc2447 |
TRIP13 |
phosphorylation |
Tyr56 |
human |
head and neck cancer |
UM-SCC-1 |
radiotherapy |
resist |
5.0 |
34111559 |
acc2448 |
TRIP13 |
phosphorylation |
Tyr56 |
human |
head and neck cancer |
UM-SCC-11A |
cetuximab |
sensitize |
5.0 |
34111559 |
acc2449 |
TRIP13 |
phosphorylation |
Tyr56 |
human |
head and neck cancer |
UM-SCC-11A |
radiotherapy |
resist |
5.0 |
34111559 |
acc2450 |
TrkB |
phosphorylation |
Tyr |
human |
neuroblastoma |
SH-SY5Y |
retinoic acid |
modulate |
4.0 |
8394722 |
acc2451 |
TrkB |
phosphorylation |
Tyr |
human |
neuroblastoma |
SMS-KCNR |
retinoic acid |
modulate |
4.0 |
8394722 |
acc2452 |
TrkB |
phosphorylation |
Tyr |
human |
neuroblastoma |
NGP-2 |
retinoic acid |
modulate |
4.0 |
8394722 |
acc2453 |
TrkB |
phosphorylation |
Tyr |
human |
neuroblastoma |
LAN-I-15N |
retinoic acid |
modulate |
4.0 |
8394722 |
acc2454 |
MERTK |
phosphorylation |
Tyr749 |
human |
leukemia |
K562 |
metformin |
modulate |
4.0 |
32460059 |
acc2455 |
TYRO3 |
phosphorylation |
Tyr681 |
human |
leukemia |
K562 |
metformin |
modulate |
4.0 |
32460059 |
acc2456 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
DXR |
inhibit |
5.0 |
32460059 |
acc2457 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
DXR |
inhibit |
5.0 |
32460059 |
acc2458 |
TYRO3 |
phosphorylation |
Tyr681 |
human |
leukemia |
OCI/AML3 |
metformin |
modulate |
4.0 |
32460059 |
acc2459 |
TYRO3 |
phosphorylation |
Tyr681 |
human |
leukemia |
THP-1 |
metformin |
modulate |
4.0 |
32460059 |
acc2460 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc2461 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc2462 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc2463 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
K562 |
TP-0903 |
inhibit |
5.0 |
32460059 |
acc2464 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
DXR |
inhibit |
5.0 |
32460059 |
acc2465 |
AXL |
phosphorylation |
Tyr779 |
human |
leukemia |
OCI/AML3 |
DXR |
inhibit |
5.0 |
32460059 |
acc2466 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
OCI/AML2 |
metformin |
modulate |
4.0 |
32460059 |
acc2467 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
OCI/AML3 |
metformin |
modulate |
4.0 |
32460059 |
acc2468 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
THP-1 |
metformin |
modulate |
4.0 |
32460059 |
acc2469 |
STAT3 |
phosphorylation |
Tyr705 |
human |
leukemia |
K562 |
metformin |
modulate |
4.0 |
32460059 |
acc2470 |
p53 |
phosphorylation |
Ser15 |
human |
melanoma |
DB-1 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2471 |
p53 |
phosphorylation |
Ser20 |
human |
melanoma |
DB-1 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2472 |
p53 |
phosphorylation |
Ser37 |
human |
melanoma |
SK-Mel-28 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2473 |
p53 |
phosphorylation |
Ser392 |
human |
melanoma |
SK-Mel-28 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2474 |
p53 |
phosphorylation |
Ser37 |
human |
melanoma |
DB-1 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2475 |
p53 |
phosphorylation |
Ser392 |
human |
melanoma |
DB-1 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2476 |
p53 |
phosphorylation |
Ser15 |
human |
melanoma |
SK-MEL-5 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2477 |
p53 |
phosphorylation |
Ser20 |
human |
melanoma |
SK-MEL-5 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2478 |
p53 |
phosphorylation |
Ser37 |
human |
melanoma |
SK-MEL-5 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2479 |
p53 |
phosphorylation |
Ser392 |
human |
melanoma |
SK-MEL-5 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2480 |
p53 |
phosphorylation |
Ser15 |
human |
melanoma |
SK-Mel-28 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2481 |
p53 |
phosphorylation |
Ser20 |
human |
melanoma |
SK-Mel-28 |
dacarbazine |
promote |
5.0 |
18791269 |
acc2482 |
CHK1 |
phosphorylation |
Ser317 |
human |
lung cancer |
A549 |
Cisplatin |
inhibit |
5.0 |
35856403 |
acc2483 |
VEGFR2 |
phosphorylation |
Tyr1059 |
human |
hepatocellular carcinoma |
SMMC-7721 |
I131-metuximab |
modulate |
4.0 |
29210217 |
acc2484 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
HL-60 |
SU4312 |
modulate |
4.0 |
34872003 |
acc2485 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
K562 |
SU4312 |
modulate |
4.0 |
34872003 |
acc2486 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
KG-1 |
SU4312 |
modulate |
4.0 |
34872003 |
acc2487 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
HL-60 |
cytarabine |
modulate |
4.0 |
34872003 |
acc2488 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
K562 |
cytarabine |
modulate |
4.0 |
34872003 |
acc2489 |
VEGFR2 |
phosphorylation |
Tyr996 |
human |
leukemia |
KG-1 |
cytarabine |
modulate |
4.0 |
34872003 |
acc2490 |
KLF4 |
phosphorylation |
Tyr20 |
human |
breast cancer |
MCF7 |
tamoxifen |
resist |
5.0 |
32084531 |
acc2491 |
KLF4 |
phosphorylation |
Tyr20 |
human |
breast cancer |
HTR |
tamoxifen |
resist |
5.0 |
32084531 |
acc2492 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
ovarian cancer |
HT29 |
PD0166285 |
modulate |
4.0 |
11719452 |
acc2493 |
Cdc2 |
phosphorylation |
Thr14 |
human |
colon cancer |
HT29 |
PD0166285 |
modulate |
4.0 |
11719452 |
acc2494 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
ovarian cancer |
HT29 |
radiation |
inhibit |
4.5 |
11719452 |
acc2495 |
Cdc2 |
phosphorylation |
Thr14 |
human |
colon cancer |
HT29 |
radiation |
inhibit |
4.5 |
11719452 |
acc2496 |
GSK3beta |
phosphorylation |
Ser9 |
human |
endometrial cancer |
RL95-2 |
Cisplatin |
inhibit |
5.0 |
33680959 |
acc2497 |
GSK3beta |
phosphorylation |
Ser9 |
human |
endometrial cancer |
ARK-2 |
Cisplatin |
inhibit |
5.0 |
33680959 |
acc2498 |
PKCepsilon |
phosphorylation |
Ser87 |
human |
breast cancer |
MCF7 |
4-OHE2 |
modulate |
4.0 |
31493422 |
acc2499 |
PKCepsilon |
phosphorylation |
Ser87 |
human |
breast cancer |
MDA-MB-231 |
4-OHE2 |
modulate |
4.0 |
31493422 |
acc2500 |
PKCepsilon |
phosphorylation |
Ser87 |
human |
cervical cancer |
HeLa |
4-OHE2 |
modulate |
4.0 |
31493422 |
acc2501 |
PKCepsilon |
phosphorylation |
Ser87 |
human |
prostate cancer |
PC3 |
4-OHE2 |
modulate |
4.0 |
31493422 |
acc2502 |
UVRAG |
phosphorylation |
Ser522 |
human |
hepatocellular carcinoma |
MHCC97H |
D4476 |
modulate |
4.0 |
30686098 |
acc2503 |
UVRAG |
phosphorylation |
Ser522 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc2504 |
UVRAG |
ubiquitination |
Lys517 |
human |
hepatocellular carcinoma |
MHCC97H |
D4476 |
modulate |
4.0 |
30686098 |
acc2505 |
UVRAG |
ubiquitination |
Lys517 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc2506 |
UVRAG |
ubiquitination |
Lys559 |
human |
hepatocellular carcinoma |
MHCC97H |
D4476 |
modulate |
4.0 |
30686098 |
acc2507 |
UVRAG |
ubiquitination |
Lys559 |
human |
hepatocellular carcinoma |
HuH-7 |
D4476 |
modulate |
4.0 |
30686098 |
acc2508 |
ITGalpha6 |
S-nitrosylation |
Cys86 |
human |
prostate cancer |
PC3 |
1400W(iNOS inhibitors) |
modulate |
4.0 |
23106339 |
acc2509 |
ITGalpha6 |
S-nitrosylation |
Cys86 |
human |
prostate cancer |
DU145 |
1400W(iNOS inhibitors) |
modulate |
4.0 |
23106339 |
acc2510 |
SOX10 |
sumoylation |
Lys55 |
human |
melanoma |
|
vemurafenib |
inhibit |
5.0 |
34087780 |
acc2511 |
LIP |
ubiquitination |
unclear |
mouse |
mesothelioma |
AB1 |
Cisplatin |
sensitize |
5.0 |
29748013 |
acc2512 |
LIP |
ubiquitination |
unclear |
human |
mesothelioma |
|
Cisplatin |
sensitize |
5.0 |
29748013 |
acc2513 |
PD-L1 |
ubiquitination |
unclear |
human |
lung cancer |
A549 |
DHA |
modulate |
4.0 |
36309154 |
acc2514 |
PD-L1 |
ubiquitination |
unclear |
mouse |
lung cancer |
LLC |
DHA |
modulate |
4.0 |
36309154 |
acc2515 |
PD-L1 |
ubiquitination |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
DHA |
modulate |
4.0 |
36309154 |
acc2516 |
PD-L1 |
ubiquitination |
unclear |
human |
hepatocellular carcinoma |
SMMC-7721 |
DHA |
modulate |
4.0 |
36309154 |
acc2517 |
stathmin |
phosphorylation |
Ser38 |
human |
ovarian cancer |
RMG-1 |
paclitaxel |
reduce |
5.0 |
36328498 |
acc2518 |
HER2 |
ubiquitination |
unclear |
human |
breast cancer |
SK-BR-3 |
peptide p37 |
modulate |
4.0 |
25898135 |
acc2519 |
HER2 |
ubiquitination |
unclear |
human |
breast cancer |
BT474 |
peptide p37 |
modulate |
4.0 |
25898135 |
acc2520 |
HER2 |
ubiquitination |
unclear |
human |
breast cancer |
ZR-75-30 |
peptide p37 |
modulate |
4.0 |
25898135 |
acc2521 |
HER2 |
ubiquitination |
unclear |
human |
breast cancer |
MDA-MB-361 |
peptide p37 |
modulate |
4.0 |
25898135 |
acc2522 |
HER2 |
ubiquitination |
unclear |
human |
breast cancer |
SK-BR-3 |
peptide p37 + trastuzumab |
modulate |
4.0 |
25898135 |
acc2523 |
JNK2 |
phosphorylation |
unclear |
human |
colon cancer |
HT29 |
TRAIL + 5-fluorouracil (5-FU) |
enhance |
5.0 |
15837763 |
acc2524 |
JNK2 |
phosphorylation |
unclear |
human |
colon cancer |
HepG2 |
TRAIL + 5-fluorouracil (6-FU) |
enhance |
5.0 |
15837763 |
acc2525 |
AMPK |
phosphorylation |
Thr172 |
human |
hepatocellular carcinoma |
HepG2 |
berberine(BBR) |
modulate |
3.0 |
16508037 |
acc2526 |
AMPK |
phosphorylation |
Thr183 |
human |
hepatocellular carcinoma |
HepG2 |
berberine(BBR) |
modulate |
3.0 |
16508037 |
acc2527 |
Nrf2 |
phosphorylation |
unclear |
human |
neuroblastoma |
IMR-32 |
DMAT(CK2 inhibitor) |
relate |
5.0 |
18273910 |
acc2528 |
MRP3 |
nitration |
unclear |
human |
colon cancer |
HT29 |
doxorubicin |
increase |
5.0 |
18922976 |
acc2529 |
MRP3 |
nitration |
unclear |
human |
colon cancer |
HT29-dx |
doxorubicin |
increase |
5.0 |
18922976 |
acc2530 |
AKT |
phosphorylation |
Thr308 |
human |
colon cancer |
HT29 |
SBA |
inhibit |
5.0 |
20503249 |
acc2531 |
AKT |
phosphorylation |
Ser473 |
human |
colon cancer |
HT29 |
SBA |
inhibit |
5.0 |
20503249 |
acc2532 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
Hep3B |
XZH-5 |
inhibit |
5.0 |
21311975 |
acc2533 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HepG2 |
XZH-5 |
inhibit |
5.0 |
21311975 |
acc2534 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
HuH-7 |
XZH-5 |
inhibit |
5.0 |
21311975 |
acc2535 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-387 |
XZH-5 |
inhibit |
5.0 |
21311975 |
acc2536 |
STAT3 |
phosphorylation |
Tyr705 |
human |
hepatocellular carcinoma |
SNU-398 |
XZH-5 |
inhibit |
5.0 |
21311975 |
acc2537 |
MKP-1 |
S-nitrosylation |
Cys258 |
human |
head and neck cancer |
MDA-1483 |
radiotherapy |
decrease |
4.5 |
22014408 |
acc2538 |
MKP-1 |
S-nitrosylation |
Cys258 |
human |
head and neck cancer |
UM-SCC-10A |
radiotherapy |
decrease |
4.5 |
22014408 |
acc2539 |
THOC5 |
phosphorylation |
Tyr225 |
human |
leukemia |
K562 |
dasatinib |
sensitize |
5.0 |
23032722 |
acc2540 |
THOC5 |
phosphorylation |
Tyr225 |
human |
leukemia |
K562 |
imatinib |
sensitize |
5.0 |
23032722 |
acc2541 |
THOC5 |
phosphorylation |
Tyr225 |
human |
leukemia |
K562 |
nilotinib |
sensitize |
5.0 |
23032722 |
acc2542 |
ITGalpha6 |
S-nitrosylation |
Cys86 |
human |
prostate cancer |
PC3 |
1400W(iNOS inhibitors) |
increase |
5.0 |
23106339 |
acc2543 |
Akt |
phosphorylation |
Thr308 |
human |
neuroblastoma |
SK-N-SH neuroblastoma cells |
okadaic acid (OA) |
enhance |
5.0 |
23127854 |
acc2544 |
Akt |
phosphorylation |
Thr308 |
human |
neuroblastoma |
SK-N-SH neuroblastoma cells |
rapamycin |
enhance |
5.0 |
23127854 |
acc2545 |
Akt |
phosphorylation |
Ser473 |
human |
neuroblastoma |
SK-N-SH neuroblastoma cells |
okadaic acid (OA) |
enhance |
5.0 |
23127854 |
acc2546 |
Akt |
phosphorylation |
Ser473 |
human |
neuroblastoma |
SK-N-SH neuroblastoma cells |
rapamycin |
enhance |
5.0 |
23127854 |
acc2547 |
PKCzeta |
ubiquitination |
Lys48 |
human |
lung cancer |
|
HOIL-1L expression |
promote |
4.5 |
25118570 |
acc2548 |
VASP |
phosphorylation |
Ser239 |
human |
lung cancer |
|
Baicalein |
promote |
5.0 |
25268843 |
acc2549 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
|
Ritonavir |
modulate |
4.0 |
25542900 |
acc2550 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
|
metformin |
inhibit |
5.0 |
25542900 |
acc2551 |
mTORC1 |
phosphorylation |
Thr172 |
human |
myeloma |
|
Ritonavir |
modulate |
4.0 |
25542900 |
acc2552 |
mTORC1 |
phosphorylation |
Thr172 |
human |
myeloma |
|
metformin |
inhibit |
5.0 |
25542900 |
acc2553 |
Trx1 |
oxidation |
unclear |
human |
breast cancer |
MDA-MB-231 |
2DG + Au |
enhance |
5.0 |
25560241 |
acc2554 |
Trx1 |
oxidation |
unclear |
human |
breast cancer |
MDA-MB-231 |
2DG + DHEA |
enhance |
5.0 |
25560241 |
acc2555 |
Trx1 |
oxidation |
unclear |
human |
prostate cancer |
PC3 |
2DG + Au |
enhance |
5.0 |
25560241 |
acc2556 |
Trx1 |
oxidation |
unclear |
human |
prostate cancer |
PC3 |
2DG + DHEA |
enhance |
5.0 |
25560241 |
acc2557 |
Trx1 |
oxidation |
unclear |
human |
prostate cancer |
DU145 |
2DG + Au |
enhance |
5.0 |
25560241 |
acc2558 |
Trx1 |
oxidation |
unclear |
human |
prostate cancer |
DU145 |
2DG + DHEA |
enhance |
5.0 |
25560241 |
acc2559 |
Trx1 |
oxidation |
Cys62 |
human |
neuroblastoma |
SH-SH5Y |
As(2-mercaptopyridine)3 |
enhance |
5.0 |
26169724 |
acc2560 |
Trx1 |
oxidation |
Cys69 |
human |
neuroblastoma |
SH-SH5Y |
As(2-mercaptopyridine)3 |
enhance |
5.0 |
26169724 |
acc2561 |
Trx1 |
oxidation |
Cys62 |
human |
neuroblastoma |
SH-SH5Y |
As(2-mercaptopyridine N-oxide)3 |
enhance |
5.0 |
26169724 |
acc2562 |
Trx1 |
oxidation |
Cys69 |
human |
neuroblastoma |
SH-SH5Y |
As(2-mercaptopyridine N-oxide)3 |
enhance |
5.0 |
26169724 |
acc2563 |
PKM2 |
glycosylation |
Arg399 |
human |
cancer |
|
MG |
inhibit |
5.0 |
26911935 |
acc2564 |
Akt |
phosphorylation |
Ser473 |
human |
leukemia |
|
sanguinarine (SNG) |
modulate |
4.0 |
27154977 |
acc2565 |
Akt |
phosphorylation |
Ser473 |
human |
ovarian cancer |
|
delphinidin |
antagonize |
5.0 |
29122484 |
acc2566 |
Smad3 |
phosphorylation |
Thr179 |
human |
hepatocellular carcinoma |
|
|
suppress |
4.5 |
29524413 |
acc2567 |
ERK1 |
phosphorylation |
Thr202 |
human |
ovarian cancer |
|
PD98049 |
increase |
5.0 |
29693189 |
acc2568 |
ERK1 |
phosphorylation |
Tyr204 |
human |
ovarian cancer |
|
PD98049 |
increase |
5.0 |
29693189 |
acc2569 |
ERK2 |
phosphorylation |
Thr185 |
human |
ovarian cancer |
|
PD98049 |
increase |
5.0 |
29693189 |
acc2570 |
ERK2 |
phosphorylation |
Tyr187 |
human |
ovarian cancer |
|
PD98049 |
increase |
5.0 |
29693189 |
acc2571 |
AKT |
phosphorylation |
Ser473 |
human |
cervical cancer |
C33A |
emodin |
modulate |
4.0 |
30057674 |
acc2572 |
AKT |
phosphorylation |
Ser473 |
human |
oral cancer |
HSC-3 |
emodin |
modulate |
4.0 |
30057674 |
acc2573 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
prostate cancer |
DU145 |
boric acid(BA) |
activate |
5.0 |
30196486 |
acc2574 |
c-Jun |
phosphorylation |
Ser63 |
human |
pancreas cancer |
PANC-1 |
ActD |
enhance |
5.0 |
30295945 |
acc2575 |
Akt |
phosphorylation |
Ser473 |
human |
gastric cancer |
HGC-27 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2576 |
Akt |
phosphorylation |
Ser473 |
human |
gastric cancer |
BGC-823 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2577 |
Stat3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
HGC-27 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2578 |
Stat3 |
phosphorylation |
Tyr705 |
human |
gastric cancer |
BGC-823 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2579 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
gastric cancer |
HGC-27 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2580 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
gastric cancer |
BGC-823 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2581 |
mTOR |
phosphorylation |
Ser2448 |
human |
gastric cancer |
HGC-27 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2582 |
mTOR |
phosphorylation |
Ser2448 |
human |
gastric cancer |
BGC-823 |
N-acetylcysteine(NAC) |
modulate |
4.0 |
32021099 |
acc2583 |
AKT |
phosphorylation |
Ser473 |
mouse |
breast cancer |
4T1 |
doxorubicin |
increase |
5.0 |
32035191 |
acc2584 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
T47D |
lapatinib |
sensitize |
5.0 |
32365111 |
acc2585 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
MCF7 |
lapatinib |
sensitize |
5.0 |
32365111 |
acc2586 |
AMPK |
phosphorylation |
Thr183 |
human |
lung cancer |
A549 |
"cis,cis,trans-[Pt(NH3)2Cl2(BEZ)(OH)] (CB)" |
conducive |
5.0 |
34388483 |
acc2587 |
AMPK |
phosphorylation |
Thr172 |
human |
lung cancer |
A549 |
"cis,cis,trans-[Pt(NH3)2Cl2(BEZ)2] (CP)" |
conducive |
5.0 |
34388483 |
acc2588 |
CDKN1B |
phosphorylation |
unclear |
human |
breast cancer |
|
NP-ALT |
modulate |
4.0 |
34446542 |
acc2589 |
RNF4 |
methylation |
Arg164 |
human |
leukemia |
|
As2O3 |
resist |
5.0 |
35622143 |
acc2590 |
BCL-2 |
phosphorylation |
Ser70 |
human |
ovarian cancer |
|
PUMA adenovirus + paclitaxel |
modulate |
4.0 |
36122664 |
acc2591 |
BCL-XL |
phosphorylation |
Ser62 |
human |
ovarian cancer |
|
PUMA adenovirus + paclitaxel |
modulate |
4.0 |
36122664 |
acc2592 |
PP2A |
methylation |
unclear |
human |
glioblastoma |
U87-MG |
radiotherapy |
increase |
4.5 |
37500619 |
acc2593 |
PP2A |
methylation |
unclear |
human |
glioblastoma |
U87-MG |
temozolomide(TMZ) |
increase |
5.0 |
37500619 |
acc2594 |
PP2A |
methylation |
unclear |
human |
glioblastoma |
U251MG |
radiotherapy |
increase |
4.5 |
37500619 |
acc2595 |
PP2A |
methylation |
unclear |
human |
glioblastoma |
U251MG |
temozolomide(TMZ) |
increase |
5.0 |
37500619 |
acc2596 |
AROS |
methylation |
Lys27 |
human |
colorectal cancer |
LoVo |
radiotherapy |
inhibit |
4.5 |
37756162 |
acc2597 |
AROS |
methylation |
Lys27 |
human |
colorectal cancer |
HCT116 |
radiotherapy |
inhibit |
4.5 |
37756162 |
acc2598 |
NADPH |
oxidation |
unclear |
human |
breast cancer |
|
carbon monoxide |
inhibit |
4.5 |
4004771 |
acc2599 |
NADPH |
oxidation |
unclear |
human |
breast cancer |
|
antibody against cytochrome P-450 |
inhibit |
4.5 |
4004771 |
acc3001 |
BAD |
phosphorylation |
unclear |
human |
colorectal cancer |
COLO205 |
gossypol |
modulate |
4.0 |
17597109 |
acc3002 |
BAD |
phosphorylation |
unclear |
human |
colorectal cancer |
HT29 |
gossypol |
modulate |
4.0 |
17597109 |
acc3003 |
BAD |
phosphorylation |
unclear |
human |
colorectal cancer |
COLO205 |
gossypol acetic acid |
modulate |
4.0 |
17597109 |
acc3004 |
BAD |
phosphorylation |
unclear |
human |
colorectal cancer |
HT29 |
gossypol acetic acid |
modulate |
4.0 |
17597109 |
acc3005 |
p53 |
acetylation |
Lys382 |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3006 |
ATM |
phosphorylation |
Ser1981 |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3007 |
Chk1 |
phosphorylation |
Ser345 |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3008 |
Chk2 |
phosphorylation |
Thr68 |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3009 |
H2AX |
phosphorylation |
unclear |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
4.0 |
19676051 |
acc3010 |
p53 |
phosphorylation |
Ser15 |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3011 |
RPA-2 |
phosphorylation |
unclear |
mouse |
ovarian carcinoma |
IGROV-1 |
ST1926 |
promote |
5.0 |
19676051 |
acc3012 |
Akt |
phosphorylation |
Ser473 |
mouse |
myocardial infarction |
|
rapamycin(RAPA) |
modulate |
4.0 |
31738412 |
acc3013 |
S6 |
phosphorylation |
Ser235 |
mouse |
myocardial infarction |
|
rapamycin(RAPA) |
modulate |
4.0 |
31738412 |
acc3014 |
S6 |
phosphorylation |
Ser236 |
mouse |
myocardial infarction |
|
rapamycin(RAPA) |
modulate |
4.0 |
31738412 |
acc3015 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
myocardial infarction |
|
rapamycin(RAPA) |
modulate |
4.0 |
31738412 |
acc3016 |
PDGFR |
phosphorylation |
Tyr |
mouse |
PI-turnover |
NIH 3T3 |
glucopiericidin A |
no effect |
2.0 |
8653074 |
acc3017 |
PLC-gamma1 |
Phosphorylation |
Tyr783 |
mouse |
PI-turnover |
NIH 3T3 |
glucopiericidin A |
no effect |
2.0 |
8653074 |
acc3018 |
SNAP-25 |
phosphorylation |
Ser187 |
rat |
Synaptic plasticity |
PC12 cells |
PMA |
no effect |
2.0 |
8662851 |
acc3019 |
PLC-gamma2 |
phosphorylation |
Tyr |
mouse |
phospholipid hydrolysis |
Plcg1(-/-) cells |
Platelet-derived growth factor (PDGF) |
modulate |
4.0 |
9685408 |
acc3020 |
STAT3 |
Phosphorylation |
Tyr705 |
human |
prostate cancer |
|
PGE2 |
modulate |
4.0 |
11779161 |
acc3021 |
Akt |
phosphorylation |
unclear |
rat |
hypertension |
|
Wortmannin |
modulate |
4.0 |
12003815 |
acc3022 |
eNOS |
phosphorylation |
Ser1176 |
rat |
hypertension |
|
Wortmannin |
modulate |
4.0 |
12003815 |
acc3023 |
nNOS |
phosphorylation |
Ser847 |
rat |
ischemia |
|
KN-93 |
modulate |
4.0 |
12218415 |
acc3024 |
ERK |
phosphorylation |
unclear |
mouse |
apoptosis of cardiac muscle cell |
HL-1 |
mercury |
modulate |
4.0 |
12788478 |
acc3025 |
GATA4 |
phosphorylation |
unclear |
mouse |
apoptosis of cardiac muscle cell |
HL-1 |
mercury |
modulate |
4.0 |
12788478 |
acc3026 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
melanoma |
LU1205 |
PD98059 + LY294002 |
modulate |
4.0 |
12821943 |
acc3027 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
melanoma |
LU1205 |
PD98059 + LY294002 |
modulate |
4.0 |
12821943 |
acc3028 |
STAT3 |
phosphorylation |
Tyr705 |
human |
melanoma |
LU1205 |
PD98059 + LY294002 |
modulate |
4.0 |
12821943 |
acc3029 |
STAT5 |
phosphorylation |
Tyr694 |
human |
melanoma |
LU1205 |
PD98059 + LY294002 |
modulate |
4.0 |
12821943 |
acc3030 |
NR2A |
phosphorylation |
Tyr1472 |
rat |
cerebral ischemia |
|
Lithium |
modulate |
4.0 |
12932824 |
acc3031 |
RhoA |
geranylgeranylation |
unclear |
human |
colon cancer |
COLO 320DM |
GGTI-298 |
modulate |
4.0 |
14598891 |
acc3032 |
Tau |
phosphorylation |
Ser199 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
lithium |
modulate |
4.0 |
15184080 |
acc3033 |
Tau |
phosphorylation |
Ser202 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
lithium |
modulate |
4.0 |
15184080 |
acc3034 |
Tau |
phosphorylation |
Thr205 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
lithium |
modulate |
4.0 |
15184080 |
acc3035 |
Tau |
phosphorylation |
Ser396 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
lithium |
modulate |
4.0 |
15184080 |
acc3036 |
Tau |
phosphorylation |
Ser404 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
lithium |
modulate |
4.0 |
15184080 |
acc3037 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
cancer |
BCap37 |
gamma-radiation + paclitaxel |
modulate |
3.0 |
15269161 |
acc3038 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
cancer |
KB |
gamma-radiation + paclitaxel |
modulate |
3.0 |
15269161 |
acc3039 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
cancer |
BCap37 |
gamma-radiation + paclitaxel |
modulate |
3.0 |
15269161 |
acc3040 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
cancer |
KB |
gamma-radiation + paclitaxel |
modulate |
3.0 |
15269161 |
acc3041 |
ATM |
phosphorylation |
Ser1981 |
human |
cancer |
A2780 |
irofulven |
modulate |
4.0 |
15269203 |
acc3042 |
ATM |
phosphorylation |
Ser1981 |
human |
cancer |
CAOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3043 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
A2780 |
irofulven |
modulate |
4.0 |
15269203 |
acc3044 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
A2780/CP70 |
irofulven |
modulate |
4.0 |
15269203 |
acc3045 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
CAOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3046 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
OVCAR3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3047 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
SKOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3048 |
NBS1 |
phosphorylation |
Ser343 |
human |
cancer |
SKOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3049 |
NBS1 |
phosphorylation |
Ser343 |
human |
cancer |
OVCAR3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3050 |
p53 |
phosphorylation |
Ser15 |
human |
cancer |
A2780 |
irofulven |
modulate |
4.0 |
15269203 |
acc3051 |
p53 |
phosphorylation |
Ser20 |
human |
cancer |
A2780 |
irofulven |
modulate |
4.0 |
15269203 |
acc3052 |
SMC1 |
phosphorylation |
Ser957 |
human |
cancer |
CAOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3053 |
SMC1 |
phosphorylation |
Ser957 |
human |
cancer |
SKOV3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3054 |
SMC1 |
phosphorylation |
Ser957 |
human |
cancer |
OVCAR3 |
irofulven |
modulate |
4.0 |
15269203 |
acc3055 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
Ganoderma lucidum |
modulate |
4.0 |
15489214 |
acc3056 |
AKT |
phosphorylation |
Thr308 |
human |
gastric carcinoma |
MKN-45 |
CH-11 |
inhibit |
5.0 |
15767780 |
acc3057 |
histone H3 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
TSA |
modulate |
3.0 |
15955204 |
acc3058 |
histone H3 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
Huh-7 |
TSA |
modulate |
3.0 |
15955204 |
acc3059 |
histone H4 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
HepG2 |
TSA |
modulate |
3.0 |
15955204 |
acc3060 |
histone H4 |
acetylation |
unclear |
human |
hepatocellular carcinoma |
Huh-7 |
TSA |
modulate |
3.0 |
15955204 |
acc3061 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
EPA + DHA |
modulate |
4.0 |
15986129 |
acc3062 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3063 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H157 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3064 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H358 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3065 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H460 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3066 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
A549 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3067 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H157 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3068 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H358 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3069 |
eIF4E |
phosphorylation |
Ser209 |
human |
lung cancer |
H460 |
rapamycin |
inhibit |
5.0 |
16103051 |
acc3070 |
ACC |
phosphorylation |
Ser79 |
human |
multiple cancer models |
"MCF-7,T98G,U87MG,PC-3,K-562,CEM T" |
AICAR |
modulate |
4.0 |
16176927 |
acc3071 |
ACC |
phosphorylation |
Ser79 |
rat |
glioma |
C6 |
AICAR |
modulate |
4.0 |
16176927 |
acc3072 |
AKT |
phosphorylation |
Ser473 |
human |
multiple cancer models |
"MCF-7,T98G,U87MG,K-562,CEM T" |
AICAR |
modulate |
4.0 |
16176927 |
acc3073 |
Akt |
phosphorylation |
Ser473 |
rat |
glioma |
C6 |
AICAR |
modulate |
4.0 |
16176927 |
acc3074 |
AMPK |
phosphorylation |
Thr172 |
human |
multiple cancer models |
"MCF-7,T98G,U87MG,K-562,CEM T" |
AICAR |
modulate |
4.0 |
16176927 |
acc3075 |
AMPK |
phosphorylation |
Thr172 |
rat |
glioma |
C6 |
AICAR |
modulate |
4.0 |
16176927 |
acc3076 |
AMPK |
phosphorylation |
Thr183 |
rat |
glioma |
C6 |
AICAR |
modulate |
4.0 |
16176927 |
acc3077 |
mTOR |
phosphorylation |
Ser1448 |
human |
multiple cancer models |
"MCF-7,T98G,U87MG,K-562,CEM T" |
AICAR |
modulate |
4.0 |
16176927 |
acc3078 |
mTOR |
phosphorylation |
Ser1448 |
rat |
glioma |
C6 |
AICAR |
modulate |
4.0 |
16176927 |
acc3079 |
Wwox |
phosphorylation |
Tyr287 |
human |
Prostate cancer |
LNCaP |
geldanamycin |
modulate |
4.0 |
16288044 |
acc3080 |
DARPP-32 |
phosphorylation |
Thr34 |
rat |
cell signaling |
PC-12/rNPFF1 |
PFR(Tic)amide + forskolin |
no effect |
2.0 |
16490283 |
acc3081 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
apoptosis |
|
TNFalpha |
modulate |
4.0 |
16717090 |
acc3082 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
apoptosis |
|
TNFalpha |
modulate |
4.0 |
16717090 |
acc3083 |
IkappaBalpha |
phosphorylation |
Ser180 |
human |
leukemia |
KBM¨C5 |
TNF |
inhibit |
5.0 |
16785236 |
acc3084 |
IKKbeta |
phosphorylation |
Ser181 |
human |
leukemia |
KBM¨C5 |
TNF |
inhibit |
5.0 |
16785236 |
acc3085 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
leukemia |
KBM¨C5 |
TNF |
inhibit |
5.0 |
16785236 |
acc3086 |
p65 |
phosphorylation |
Ser536 |
human |
leukemia |
KBM¨C5 |
TNF |
inhibit |
5.0 |
16785236 |
acc3087 |
Akt |
phosphorylation |
unclear |
rat |
atherosclerosis |
|
NQ304 |
modulate |
4.0 |
16875883 |
acc3088 |
ERK1 |
phosphorylation |
unclear |
rat |
atherosclerosis |
|
NQ304 |
modulate |
4.0 |
16875883 |
acc3089 |
ERK2 |
phosphorylation |
unclear |
rat |
atherosclerosis |
|
NQ304 |
modulate |
4.0 |
16875883 |
acc3090 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
HCV |
HeLa |
H2O2 |
modulate |
4.0 |
17030858 |
acc3091 |
JNK |
phosphorylation |
Thr183 |
human |
lung cancer |
H1299 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3092 |
JNK |
phosphorylation |
Tyr185 |
human |
lung cancer |
H1299 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3093 |
JNK |
phosphorylation |
Thr183 |
human |
lung cancer |
A549 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3094 |
JNK |
phosphorylation |
Tyr185 |
human |
lung cancer |
A549 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3095 |
JNK |
phosphorylation |
Thr183 |
human |
breast cancer |
MCF-7 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3096 |
JNK |
phosphorylation |
Tyr185 |
human |
breast cancer |
MCF-7 |
RASSF1A |
modulate |
4.0 |
17088994 |
acc3097 |
CREB |
phosphorylation |
Ser133 |
mouse |
memory impairment |
|
oroxylin A |
modulate |
4.0 |
17174385 |
acc3098 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
choriocarcinoma |
JEG-3 |
pervanadate |
no effect |
2.0 |
17237409 |
acc3099 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
choriocarcinoma |
JEG-3 |
pervanadate |
no effect |
2.0 |
17237409 |
acc3100 |
STAT1 |
phosphorylation |
Tyr701 |
human |
choriocarcinoma |
JEG-3 |
pervanadate |
no effect |
2.0 |
17237409 |
acc3101 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Ischemia-reperfusion injury |
|
L-NAME |
modulate |
4.0 |
17268885 |
acc3102 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Ischemia-reperfusion injury |
|
L-NAME |
modulate |
4.0 |
17268885 |
acc3103 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Ischemia-reperfusion injury |
|
PD98059 |
modulate |
4.0 |
17268885 |
acc3104 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Ischemia-reperfusion injury |
|
PD98059 |
modulate |
4.0 |
17268885 |
acc3105 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Ischemia-reperfusion injury |
|
FR167653 |
modulate |
4.0 |
17268885 |
acc3106 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Ischemia-reperfusion injury |
|
FR167653 |
modulate |
4.0 |
17268885 |
acc3107 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Ischemia-reperfusion injury |
|
L-NAME |
modulate |
4.0 |
17268885 |
acc3108 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Ischemia-reperfusion injury |
|
L-NAME |
modulate |
4.0 |
17268885 |
acc3109 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Ischemia-reperfusion injury |
|
PD98059 |
modulate |
4.0 |
17268885 |
acc3110 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Ischemia-reperfusion injury |
|
PD98059 |
modulate |
4.0 |
17268885 |
acc3111 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Ischemia-reperfusion injury |
|
FR167653 |
modulate |
4.0 |
17268885 |
acc3112 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Ischemia-reperfusion injury |
|
FR167653 |
modulate |
4.0 |
17268885 |
acc3113 |
p38 MAPK |
phosphorylation |
unclear |
mouse |
Ischemia-reperfusion injury |
|
L-NAME |
modulate |
4.0 |
17268885 |
acc3114 |
p38 MAPK |
phosphorylation |
unclear |
mouse |
Ischemia-reperfusion injury |
|
PD98059 |
modulate |
4.0 |
17268885 |
acc3115 |
p38 MAPK |
phosphorylation |
unclear |
mouse |
Ischemia-reperfusion injury |
|
FR167653 |
modulate |
4.0 |
17268885 |
acc3116 |
histone H3 |
phosphorylation |
Ser10 |
human |
breast cancer |
MCF-7 |
doxorubicin |
modulate |
3.0 |
17363502 |
acc3117 |
histone H3 |
phosphorylation |
Ser10 |
human |
breast cancer |
MCF-7 |
cisplatin |
modulate |
3.0 |
17363502 |
acc3118 |
histone H4 |
trimethylation |
Lys20 |
human |
breast cancer |
MCF-7 |
doxorubicin |
modulate |
3.0 |
17363502 |
acc3119 |
histone H4 |
trimethylation |
Lys20 |
human |
breast cancer |
MCF-7 |
cisplatin |
modulate |
3.0 |
17363502 |
acc3120 |
AKT |
phosphorylation |
Ser473 |
human |
mast cell activation |
hCBMC |
anti-FcRIalpha mAb designated 15/1 |
modulate |
3.0 |
17368811 |
acc3121 |
AKT |
phosphorylation |
Ser473 |
human |
mast cell activation |
hCBMC |
Omalizumab |
modulate |
4.0 |
17368811 |
acc3122 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
cancer |
SMMC-7721 |
Lithium |
modulate |
4.0 |
18247328 |
acc3123 |
ERK1 |
phosphorylation |
Thr202 |
human |
growth arrest |
ML-1 |
TPA |
modulate |
4.0 |
18270969 |
acc3124 |
ERK1 |
phosphorylation |
Tyr204 |
human |
growth arrest |
ML-1 |
TPA |
modulate |
4.0 |
18270969 |
acc3125 |
ERK2 |
phosphorylation |
Thr185 |
human |
growth arrest |
ML-1 |
TPA |
modulate |
4.0 |
18270969 |
acc3126 |
ERK2 |
phosphorylation |
Tyr187 |
human |
growth arrest |
ML-1 |
TPA |
modulate |
4.0 |
18270969 |
acc3127 |
IPP5 |
phosphorylation |
Thr40 |
human |
colorectal adenocarcinoma |
SW480 |
IPP5 OE |
modulate |
3.0 |
18310074 |
acc3128 |
IPP5 |
phosphorylation |
Thr40 |
human |
colorectal adenocarcinoma |
SW620 |
IPP5 OE |
modulate |
3.0 |
18310074 |
acc3129 |
AKT |
phosphorylation |
unclear |
human |
ependymoma |
IGRG88 |
gefitinib + radiotherapy |
modulate |
4.0 |
18386816 |
acc3130 |
AKT |
phosphorylation |
unclear |
human |
ependymoma |
IGREP83 |
gefitinib + radiotherapy |
modulate |
4.0 |
18386816 |
acc3131 |
MAPK |
phosphorylation |
unclear |
human |
ependymoma |
IGRG88 |
gefitinib + radiotherapy |
modulate |
4.0 |
18386816 |
acc3132 |
MAPK |
phosphorylation |
unclear |
human |
ependymoma |
IGREP83 |
gefitinib + radiotherapy |
modulate |
4.0 |
18386816 |
acc3133 |
eIF2alpha |
phosphorylation |
Ser51 |
rat |
hypomyelination and oligodendrocyte loss |
|
Salubrinal |
modulate |
4.0 |
18818381 |
acc3134 |
Tau |
phosphorylation |
Tyr18 |
human |
Alzheimer's disease (AD) |
SHSY-5Y |
Abeta |
increase |
4.0 |
19158430 |
acc3135 |
Tau |
phosphorylation |
Ser396 |
human |
Alzheimer's disease (AD) |
SHSY-5Y |
Abeta |
increase |
4.0 |
19158430 |
acc3136 |
Tau |
phosphorylation |
Ser404 |
human |
Alzheimer's disease (AD) |
SHSY-5Y |
Abeta |
increase |
4.0 |
19158430 |
acc3137 |
Tau |
phosphorylation |
Ser396 |
human |
Alzheimer's disease (AD) |
SHSY-5Y |
roscovitine |
modulate |
4.0 |
19158430 |
acc3138 |
Tau |
phosphorylation |
Ser404 |
human |
Alzheimer's disease (AD) |
SHSY-5Y |
roscovitine |
modulate |
4.0 |
19158430 |
acc3139 |
Akt |
phosphorylation |
Ser473 |
rabbit |
infarction |
|
Glimepiride |
modulate |
4.0 |
19202319 |
acc3140 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
Alzheimer's disease (AD) |
|
A-582941 |
modulate |
4.0 |
19230830 |
acc3141 |
Tau |
phosphorylation |
Ser202 |
mouse |
Alzheimer's disease (AD) |
|
A-582941 |
modulate |
4.0 |
19230830 |
acc3142 |
Tau |
phosphorylation |
Thr205 |
mouse |
Alzheimer's disease (AD) |
|
A-582941 |
modulate |
4.0 |
19230830 |
acc3143 |
ERK1 |
phosphorylation |
Thr202 |
human |
HCV |
OR6 |
Cyclosporine A |
modulate |
4.0 |
19492433 |
acc3144 |
ERK1 |
phosphorylation |
Tyr204 |
human |
HCV |
OR6 |
Cyclosporine A |
modulate |
4.0 |
19492433 |
acc3145 |
ERK2 |
phosphorylation |
Thr185 |
human |
HCV |
OR6 |
Cyclosporine A |
modulate |
4.0 |
19492433 |
acc3146 |
ERK2 |
phosphorylation |
Tyr187 |
human |
HCV |
OR6 |
Cyclosporine A |
modulate |
4.0 |
19492433 |
acc3147 |
ATM |
phosphorylation |
Ser1981 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3148 |
Cdc25C |
phosphorylation |
Ser216 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3149 |
Cdc25C |
phosphorylation |
Ser198 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3150 |
Cdk1 |
phosphorylation |
Tyr15 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3151 |
Chk1 |
phosphorylation |
Ser317 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3152 |
Chk2 |
phosphorylation |
Thr68 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3153 |
c-Jun |
phosphorylation |
Ser63 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3154 |
JNK |
phosphorylation |
Thr183 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3155 |
JNK |
phosphorylation |
Tyr185 |
human |
Hepatocellular carcinoma (HCC) |
Hep3B |
HKH40A |
modulate |
4.0 |
19530246 |
acc3156 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Nephritis |
|
candesartan |
modulate |
4.0 |
19846573 |
acc3157 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
Nephritis |
|
candesartan |
modulate |
4.0 |
19846573 |
acc3158 |
ERK2 |
phosphorylation |
Thr218 |
rat |
Nephritis |
|
candesartan |
modulate |
4.0 |
19846573 |
acc3159 |
ERK2 |
phosphorylation |
Tyr220 |
rat |
Nephritis |
|
candesartan |
modulate |
4.0 |
19846573 |
acc3160 |
CREB |
phosphorylation |
Ser133 |
mouse |
depression |
|
flavonol |
modulate |
4.0 |
19917299 |
acc3161 |
Smad1 |
phosphorylation |
unclear |
mouse |
Fibrodysplasia ossificans progressiva (FOP) |
C2C12 |
mutant ALK2-R206H receptor |
modulate |
3.0 |
19929436 |
acc3162 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
infarction |
|
ischemic post-conditioning |
modulate |
3.0 |
20054613 |
acc3163 |
GSK3alpha |
phosphorylation |
Ser21 |
mouse |
Fragile X syndrome (FXS) |
|
Lithium |
modulate |
4.0 |
20600866 |
acc3164 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
Fragile X syndrome (FXS) |
|
Lithium |
modulate |
4.0 |
20600866 |
acc3165 |
AMPK |
phosphorylation |
Thr172 |
human |
apoptosis |
HUVEC |
adiponectin |
modulate |
4.0 |
20675307 |
acc3166 |
AMPK |
phosphorylation |
Thr183 |
human |
apoptosis |
HUVEC |
adiponectin |
modulate |
4.0 |
20675307 |
acc3167 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
inflammation |
|
"icariin derivative (3,5-dihydroxy-4'-methoxy-6'',6''-dimethy1-4'',5''-dihydropyrano[2'',3'':7,8]-fl |
modulate |
4.0 |
20686223 |
acc3168 |
p38 |
phosphorylation |
Tyr182 |
mouse |
inflammation |
|
"icariin derivative (3,5-dihydroxy-4'-methoxy-6'',6''-dimethy1-4'',5''-dihydropyrano[2'',3'':7,8]-fl |
modulate |
4.0 |
20686223 |
acc3169 |
STAT1 |
phosphorylation |
Tyr701 |
human |
lung cancer |
cancer cells from MPE |
cisplatin |
resist |
5.0 |
20814891 |
acc3170 |
STAT1 |
phosphorylation |
Tyr701 |
human |
lung cancer |
PC14PE6/AS2 |
cisplatin |
inhibit |
5.0 |
20814891 |
acc3171 |
STAT1 |
phosphorylation |
Tyr701 |
human |
nasopharyngeal carcinoma |
HONE1-cis6 |
cisplatin |
inhibit |
5.0 |
20814891 |
acc3172 |
STAT1 |
phosphorylation |
Tyr701 |
human |
nasopharyngeal carcinoma |
HONE1 |
cisplatin |
inhibit |
5.0 |
20814891 |
acc3173 |
p53 |
phosphorylation |
Ser18 |
mouse |
insulin resistant |
|
N-Acetyl cysteine (NAC) |
no effect |
2.0 |
20956556 |
acc3174 |
AKT |
phosphorylation |
Ser473 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3175 |
ERK1 |
phosphorylation |
Thr202 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3176 |
ERK1 |
phosphorylation |
Tyr204 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3177 |
ERK2 |
phosphorylation |
Thr185 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3178 |
ERK2 |
phosphorylation |
Tyr187 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3179 |
JNK |
phosphorylation |
Tyr185 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3180 |
JNK |
phosphorylation |
Thr183 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3181 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3182 |
p38 MAPK |
phosphorylation |
Tyr180 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3183 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
cataract |
SRA 01-04 |
honokiol |
modulate |
4.0 |
20965163 |
acc3184 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
memory impairment and neuronal cell death |
|
4-O-methylhonokiol |
modulate |
4.0 |
20974250 |
acc3185 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
memory impairment and neuronal cell death |
|
4-O-methylhonokiol |
modulate |
4.0 |
20974250 |
acc3186 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
memory impairment and neuronal cell death |
|
4-O-methylhonokiol |
modulate |
4.0 |
20974250 |
acc3187 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
memory impairment and neuronal cell death |
|
4-O-methylhonokiol |
modulate |
4.0 |
20974250 |
acc3188 |
eNOS |
phosphorylation |
Ser1177 |
rat |
insulin resistance |
|
Losartan |
modulate |
4.0 |
21153603 |
acc3189 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistance |
|
Losartan |
modulate |
4.0 |
21153603 |
acc3190 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3191 |
ERK1 |
phosphorylation |
Thr202 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3192 |
ERK1 |
phosphorylation |
Tyr204 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3193 |
ERK2 |
phosphorylation |
Thr185 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3194 |
ERK2 |
phosphorylation |
Tyr187 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3195 |
p38alpha |
phosphorylation |
Thr180 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3196 |
p38alpha |
phosphorylation |
Tyr182 |
human |
colorectal cancer |
HT-29 |
LPS |
modulate |
4.0 |
21363926 |
acc3197 |
AMPKalpha |
phosphorylation |
Thr172 |
human |
renal cancer |
H295R |
rosiglitazone |
modulate |
4.0 |
21376716 |
acc3198 |
RB |
phosphorylation |
Ser780 |
human |
renal cancer |
SW13 |
rosiglitazone |
modulate |
4.0 |
21376716 |
acc3199 |
Lyn |
phosphorylation |
unclear |
mouse |
Delayed-Type Hypersensitivity |
"RBL-1,RBL-2H3" |
Valencene |
modulate |
4.0 |
21380805 |
acc3200 |
Lyn |
phosphorylation |
unclear |
mouse |
Delayed-Type Hypersensitivity |
"RBL-1,RBL-2H3" |
cyperus rotundus (CRE) |
modulate |
4.0 |
21380805 |
acc3201 |
Tau |
phosphorylation |
Ser202 |
mouse |
neurodegeneration |
|
Roscovitine |
modulate |
4.0 |
21435449 |
acc3202 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
diabetic |
|
T-cell vaccination (TCV) |
modulate |
4.0 |
21519350 |
acc3203 |
JNK |
phosphorylation |
Tyr185 |
mouse |
fatigue |
HEK 293 |
N-acetylcysteine (NAC) |
modulate |
4.0 |
21827635 |
acc3204 |
JNK |
phosphorylation |
Thr183 |
mouse |
fatigue |
HEK 293 |
N-acetylcysteine (NAC) |
modulate |
4.0 |
21827635 |
acc3205 |
Akt |
phosphorylation |
Ser473 |
rat |
Alzheimer¡¯s disease |
|
|
modulate |
4.0 |
21884524 |
acc3206 |
Akt |
phosphorylation |
Ser473 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3207 |
IRS1 |
phosphorylation |
Tyr941 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3208 |
NF-kappaB p65 |
phosphorylation |
Ser276 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3209 |
PKC lambda |
phosphorylation |
Thr403 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3210 |
PKC zeta |
phosphorylation |
Thr410 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3211 |
PKC gamma |
phosphorylation |
Thr514 |
mouse |
high glucose |
3T3L1 |
"H(2)S, L-cysteine (LC)" |
modulate |
4.0 |
21953448 |
acc3212 |
Elk-1 |
phosphorylation |
Ser383 |
rat |
diabetes vascular complications |
A10 |
EGCG |
modulate |
4.0 |
21973165 |
acc3213 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetes vascular complications |
A10 |
EGCG |
modulate |
4.0 |
21973165 |
acc3214 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetes vascular complications |
A10 |
EGCG |
modulate |
4.0 |
21973165 |
acc3215 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetes vascular complications |
A10 |
EGCG |
modulate |
4.0 |
21973165 |
acc3216 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetes vascular complications |
A10 |
EGCG |
modulate |
4.0 |
21973165 |
acc3217 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3218 |
GS |
phosphorylation |
Ser641 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3219 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3220 |
PTEN |
phosphorylation |
Ser380 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3221 |
PTEN |
phosphorylation |
Thr382 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3222 |
PTEN |
phosphorylation |
Thr383 |
mouse |
diabetic |
|
TPEN |
modulate |
4.0 |
22000581 |
acc3223 |
ERK1 |
Phosphorylation |
Thr202 |
pig |
Fibrotic disorder |
porcine valvular interstitial cells |
Terguride |
modulate |
4.0 |
22049464 |
acc3224 |
ERK1 |
Phosphorylation |
Tyr204 |
pig |
Fibrotic disorder |
porcine valvular interstitial cells |
Terguride |
modulate |
4.0 |
22049464 |
acc3225 |
ERK2 |
Phosphorylation |
Thr185 |
pig |
Fibrotic disorder |
porcine valvular interstitial cells |
Terguride |
modulate |
4.0 |
22049464 |
acc3226 |
ERK2 |
Phosphorylation |
Tyr187 |
pig |
Fibrotic disorder |
porcine valvular interstitial cells |
Terguride |
modulate |
4.0 |
22049464 |
acc3227 |
Akt |
phosphorylation |
unclear |
mouse |
abnormal platelet function |
|
alpha-PGG |
modulate |
4.0 |
22073153 |
acc3228 |
IRS1 |
phosphorylation |
unclear |
mouse |
abnormal platelet function |
|
alpha-PGG |
modulate |
4.0 |
22073153 |
acc3229 |
Titin |
phosphorylation |
unclear |
dog |
hypertension |
|
sildenafil |
modulate |
4.0 |
22144574 |
acc3230 |
Akt |
phosphorylation |
Ser473 |
rat |
pain |
|
Carrageenan |
modulate |
4.0 |
22243518 |
acc3231 |
SRC-3 |
phosphorylation |
Ser857 |
human |
lung cancer |
H1299 |
ERK3 OE |
modulate |
3.0 |
22505454 |
acc3232 |
SRC-3 |
phosphorylation |
Ser857 |
human |
lung cancer |
A549 |
ERK3 OE |
modulate |
3.0 |
22505454 |
acc3233 |
Akt |
phosphorylation |
Ser473 |
rat |
acute hyperhomocysteinemia |
|
Homocysteine |
modulate |
4.0 |
22525229 |
acc3234 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
acute hyperhomocysteinemia |
|
Homocysteine |
modulate |
4.0 |
22525229 |
acc3235 |
Tau |
phosphorylation |
Ser396 |
rat |
acute hyperhomocysteinemia |
|
Homocysteine |
modulate |
4.0 |
22525229 |
acc3236 |
Cdc2 |
phosphorylation |
Tyr15 |
human |
cancer |
HCT116 |
doxorubicin |
modulate |
4.0 |
22589537 |
acc3237 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
HCT116 |
doxorubicin |
modulate |
4.0 |
22589537 |
acc3238 |
VEGFR2 |
phosphorylation |
Tyr1175 |
human |
angiogenesis |
HUVEC |
Triphala churna |
modulate |
4.0 |
22937129 |
acc3239 |
RelA |
phosphorylation |
Ser536 |
human |
hepatic fibrosis |
LX-2 |
P6 |
modulate |
4.0 |
22996371 |
acc3240 |
E2F1 |
phosphorylation |
Ser364 |
human |
breast cancer |
MCF-7 |
vinorelbine |
inhibit |
5.0 |
23306062 |
acc3241 |
E2F1 |
phosphorylation |
Ser364 |
human |
breast cancer |
MCF-7 |
docetaxel |
inhibit |
5.0 |
23306062 |
acc3242 |
E2F1 |
phosphorylation |
Ser364 |
human |
breast cancer |
MDA-MB-231 |
vinorelbine |
inhibit |
5.0 |
23306062 |
acc3243 |
E2F1 |
phosphorylation |
Ser364 |
human |
breast cancer |
MDA-MB-231 |
docetaxel |
inhibit |
5.0 |
23306062 |
acc3244 |
p53 |
phosphorylation |
Ser15 |
human |
breast cancer |
MCF-7 |
Auranofin |
increase |
5.0 |
23342042 |
acc3245 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MCF-7 |
Selenocystine + Auranofin |
modulate |
4.0 |
23342042 |
acc3246 |
Chk1 |
phosphorylation |
Ser345 |
human |
cancer |
HeLa |
Hyperthermia |
decrease |
4.5 |
23383325 |
acc3247 |
Chk2 |
phosphorylation |
Thr68 |
human |
cancer |
HeLa |
Hyperthermia |
decrease |
4.5 |
23383325 |
acc3248 |
beta-catenin |
phosphorylation |
Ser675 |
mouse |
diabetic |
|
GLP¨C1(28¨C36)amide |
modulate |
4.0 |
23571712 |
acc3249 |
CREB |
phosphorylation |
unclear |
human |
inflammatory bowel disease |
KRJ-I |
MRS1754 |
modulate |
4.0 |
23638125 |
acc3250 |
CREB |
phosphorylation |
unclear |
human |
inflammatory bowel disease |
KRJ-I |
MRS1754 |
modulate |
4.0 |
23638125 |
acc3251 |
TPH-1 |
phosphorylation |
unclear |
human |
inflammatory bowel disease |
KRJ-I |
NECA |
modulate |
4.0 |
23638125 |
acc3252 |
TPH-1 |
phosphorylation |
unclear |
human |
inflammatory bowel disease |
KRJ-I |
NECA |
modulate |
4.0 |
23638125 |
acc3253 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Multiple Sclerosis (MS) |
|
CB52 |
modulate |
4.0 |
24036373 |
acc3254 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Multiple Sclerosis (MS) |
|
CB52 |
modulate |
4.0 |
24036373 |
acc3255 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Multiple Sclerosis (MS) |
|
CB52 |
modulate |
4.0 |
24036373 |
acc3256 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Multiple Sclerosis (MS) |
|
CB52 |
modulate |
4.0 |
24036373 |
acc3257 |
Akt |
phosphorylation |
Ser473 |
mouse |
hyperammonic brain disorder |
|
ammonia |
modulate |
4.0 |
24044899 |
acc3258 |
EGFR |
phosphorylation |
Tyr846 |
mouse |
hyperammonic brain disorder |
|
ammonia |
modulate |
4.0 |
24044899 |
acc3259 |
EGFR |
phosphorylation |
Tyr1068 |
mouse |
hyperammonic brain disorder |
|
ammonia |
modulate |
4.0 |
24044899 |
acc3260 |
ERK |
phosphorylation |
Tyr204 |
mouse |
hyperammonic brain disorder |
|
ammonia |
modulate |
4.0 |
24044899 |
acc3261 |
Bcl-2 |
phosphorylation |
Thr56 |
human |
leukemia |
Jurkat T |
nocodazole |
modulate |
4.0 |
24166139 |
acc3262 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
leukemia |
Jurkat T |
nocodazole |
modulate |
4.0 |
24166139 |
acc3263 |
Bcl-2 |
phosphorylation |
Ser87 |
human |
leukemia |
Jurkat T |
nocodazole |
modulate |
4.0 |
24166139 |
acc3264 |
Bim |
phosphorylation |
unclear |
human |
leukemia |
Jurkat T |
nocodazole |
modulate |
4.0 |
24166139 |
acc3265 |
Hsp27 |
phosphorylation |
Ser82 |
human |
cervical cancer |
HeLa |
TRAIL |
increase |
5.0 |
24176848 |
acc3266 |
Hsp27 |
phosphorylation |
Ser82 |
human |
cervical cancer |
HeLa |
LY303511 + TRAIL |
modulate |
4.0 |
24176848 |
acc3267 |
p65 |
phosphorylation |
unclear |
rat |
pancreatitis |
|
Pioglitazone |
modulate |
4.0 |
24185678 |
acc3268 |
GSK3beta |
phosphorylation |
Ser9 |
human |
neuroblastoma |
SH-SY5Y |
curcumin |
modulate |
2.0 |
24188406 |
acc3269 |
Tau |
phosphorylation |
Thr231 |
human |
neuroblastoma |
SH-SY5Y |
curcumin |
modulate |
2.0 |
24188406 |
acc3270 |
Tau |
phosphorylation |
Ser396 |
human |
neuroblastoma |
SH-SY5Y |
curcumin |
modulate |
2.0 |
24188406 |
acc3271 |
MGMT |
ubiquitination |
Cys145 |
human |
glioblastoma (GBM) |
T98 |
disulfiram (DSF) |
modulate |
4.0 |
24193513 |
acc3272 |
Tau |
acetylation |
Lys163 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3273 |
Tau |
acetylation |
Lys174 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3274 |
Tau |
acetylation |
Lys180 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3275 |
CK2alpha |
phosphorylation |
Thr360 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3276 |
CK2alpha |
phosphorylation |
Ser362 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3277 |
GSK3beta |
phosphorylation |
Tyr216 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3278 |
SIRT1 |
phosphorylation |
Ser649 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3279 |
Tau |
phosphorylation |
Ser202 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3280 |
Tau |
phosphorylation |
Thr205 |
human |
Alzheimer's disease (AD) |
N2aSwe |
Cilostazol + resveratrol |
modulate |
4.0 |
24254769 |
acc3281 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
SMMC-7721 |
Ethyl pyruvate |
modulate |
4.0 |
24361892 |
acc3282 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
HepG2 |
Ethyl pyruvate |
modulate |
4.0 |
24361892 |
acc3283 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
HCC-LM3 |
Ethyl pyruvate |
modulate |
4.0 |
24361892 |
acc3284 |
Akt |
phosphorylation |
Ser473 |
mouse |
Hepatocellular carcinoma |
|
Ethyl pyruvate |
modulate |
4.0 |
24361892 |
acc3285 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
pain |
|
acupuncture |
promote |
4.5 |
24524846 |
acc3286 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
pain |
|
acupuncture |
promote |
4.5 |
24524846 |
acc3287 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
pain |
|
acupuncture |
promote |
4.5 |
24524846 |
acc3288 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
pain |
|
acupuncture |
promote |
4.5 |
24524846 |
acc3289 |
STAT3 |
phosphorylation |
unclear |
human |
insulin resistant |
HUVEC |
miR-492 |
modulate |
3.0 |
24526524 |
acc3290 |
STAT3 |
phosphorylation |
unclear |
mouse |
insulin resistant |
3T3-L1 |
miR-492 |
modulate |
3.0 |
24526524 |
acc3291 |
AKT |
phosphorylation |
Ser473 |
human |
diabetes |
rhabdomyosarcoma(RD) |
C2-ceramide |
modulate |
4.0 |
24650522 |
acc3292 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetes |
C2C12 |
C2-ceramide |
modulate |
4.0 |
24650522 |
acc3293 |
IRS1 |
phosphorylation |
Ser473 |
human |
diabetes |
rhabdomyosarcoma(RD) |
C2-ceramide + rapamycin |
modulate |
4.0 |
24650522 |
acc3294 |
IRS1 |
phosphorylation |
Ser473 |
rat |
diabetes |
C2C12 |
C2-ceramide + rapamycin |
modulate |
4.0 |
24650522 |
acc3295 |
ERRgamma |
phosphorylation |
Ser57 |
human |
breast cancer |
MCF-7 |
tamoxifen (TAM) |
inhibit |
5.0 |
24684682 |
acc3296 |
ERRgamma |
phosphorylation |
Ser81 |
human |
breast cancer |
MCF-7 |
tamoxifen (TAM) |
inhibit |
5.0 |
24684682 |
acc3297 |
ERRgamma |
phosphorylation |
Ser219 |
human |
breast cancer |
MCF-7 |
tamoxifen (TAM) |
inhibit |
5.0 |
24684682 |
acc3298 |
4EBP1 |
phosphorylation |
Thr70 |
rat |
Parkinson's disease (PD) |
PC12 |
"6-hydroxydopamine,N-methyl-4-phenylpyridine,rotenone" |
modulate |
4.0 |
24726895 |
acc3299 |
mTOR |
phosphorylation |
Ser2448 |
rat |
Parkinson's disease (PD) |
PC12 |
"6-hydroxydopamine,N-methyl-4-phenylpyridine,rotenone" |
modulate |
4.0 |
24726895 |
acc3300 |
S6K1 |
phosphorylation |
Thr389 |
Rat |
Parkinson's disease (PD) |
PC12 |
"6-hydroxydopamine,N-methyl-4-phenylpyridine,rotenone" |
modulate |
4.0 |
24726895 |
acc3301 |
cortactin |
phosphorylation |
Tyr421 |
human |
HCC |
HUH-7 |
"focal amplicon, 1q24.1-24.3" |
modulate |
3.0 |
24812600 |
acc3302 |
Src |
phosphorylation |
Tyr426 |
human |
HCC |
HepG2¡¢Hep3B¡¢HUH-7¡¢SMMC-7721¡¢SK-HEP-1¡¢Li-7 |
"focal amplicon, 1q24.1-24.2" |
modulate |
3.0 |
24812600 |
acc3303 |
Src |
phosphorylation |
Tyr416 |
human |
HCC |
HepG2¡¢Hep3B¡¢HUH-7¡¢SMMC-7721¡¢SK-HEP-1¡¢Li-7 |
"focal amplicon, 1q24.1-24.2" |
modulate |
3.0 |
24812600 |
acc3304 |
IRS1 |
glycosylation |
unclear |
rat |
myocardial ischaemia/reperfusion (MI/R) injury |
"Neonatal rat Cardiomyocytes, NRCMs" |
glucose |
modulate |
4.0 |
24845581 |
acc3305 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial ischaemia/reperfusion (MI/R) injury |
"Neonatal rat Cardiomyocytes, NRCMs" |
glucose |
modulate |
4.0 |
24845581 |
acc3306 |
IRS1 |
phosphorylation |
Tyr |
rat |
myocardial ischaemia/reperfusion (MI/R) injury |
"Neonatal rat Cardiomyocytes, NRCMs" |
glucose |
modulate |
4.0 |
24845581 |
acc3307 |
AKT |
phosphorylation |
unclear |
human |
HIV |
CHME5 |
ginsenoside Rb1 |
modulate |
4.0 |
24983400 |
acc3308 |
GSK3beta |
phosphorylation |
Ser9 |
human |
HIV |
CHME5 |
ginsenoside Rb1 |
modulate |
4.0 |
24983400 |
acc3309 |
AKT |
phosphorylation |
Ser473 |
human |
colorectal cancer |
HT-29 |
cPLA2alpha OE |
modulate |
3.0 |
25365190 |
acc3310 |
Akt |
phosphorylation |
unclear |
mouse |
gastritis |
|
Pc-ME |
modulate |
4.0 |
25446596 |
acc3311 |
IkappaBalpha |
phosphorylation |
unclear |
mouse |
gastritis |
|
Pc-ME |
modulate |
4.0 |
25446596 |
acc3312 |
Src |
phosphorylation |
unclear |
mouse |
gastritis |
|
Pc-ME |
modulate |
4.0 |
25446596 |
acc3313 |
Syk |
phosphorylation |
unclear |
mouse |
gastritis |
|
Pc-ME |
modulate |
4.0 |
25446596 |
acc3314 |
TRPV1 |
phosphorylation |
Ser800 |
rat |
muscle mechanical hyperalgesia |
|
AMG9810 |
modulate |
4.0 |
25451626 |
acc3315 |
Akt |
phosphorylation |
Ser473 |
rabbit |
atherosclerosis |
|
des-fluoro-anacetrapib |
modulate |
4.0 |
25633313 |
acc3316 |
IkappaBalpha |
phosphorylation |
unclear |
human |
colon cancer |
SW620 |
As4O6 |
modulate |
4.0 |
25845556 |
acc3317 |
p65 |
phosphorylation |
unclear |
rat |
Acute lung injury (ALI) |
|
Magnolol |
modulate |
4.0 |
26072062 |
acc3318 |
ERK1 |
phosphorylation |
Thr202 |
rat |
Type 4 cardiorenal syndrome |
|
apocynin |
modulate |
4.0 |
26109504 |
acc3319 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Type 4 cardiorenal syndrome |
|
apocynin |
modulate |
4.0 |
26109504 |
acc3320 |
ERK2 |
phosphorylation |
Thr185 |
rat |
Type 4 cardiorenal syndrome |
|
apocynin |
modulate |
4.0 |
26109504 |
acc3321 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
Type 4 cardiorenal syndrome |
|
apocynin |
modulate |
4.0 |
26109504 |
acc3322 |
Akt |
phosphorylation |
unclear |
rat |
pain |
|
morphine |
modulate |
4.0 |
26162710 |
acc3323 |
AKT |
phosphorylation |
Ser473 |
human |
Multiple Sclerosis |
humanized mice |
Treg-mediated suppression |
resist |
4.5 |
26193267 |
acc3324 |
cav-1 |
phosphorylation |
Tyr14 |
mouse |
Microphageapoptosis |
macrophage |
EPS |
modulate |
4.0 |
26424181 |
acc3325 |
p21 |
methylation |
Arg156 |
human |
colorectal cancer |
HCT116 |
doxorubicin |
inhibit |
5.0 |
26436589 |
acc3326 |
p21 |
methylation |
Arg156 |
human |
cervicalcancer |
HeLa |
doxorubicin |
inhibit |
5.0 |
26436589 |
acc3327 |
p21 |
phosphorylation |
Thr145 |
human |
colorectal cancer |
HCT116 |
doxorubicin |
inhibit |
5.0 |
26436589 |
acc3328 |
p21 |
phosphorylation |
Thr145 |
human |
cervicalcancer |
HeLa |
doxorubicin |
inhibit |
5.0 |
26436589 |
acc3329 |
Rab13 |
phosphorylation |
Ser111 |
human |
Parkinson's disease (PD) |
HEK293 |
PINK1 |
modulate |
4.0 |
26471730 |
acc3330 |
Rab8A |
phosphorylation |
Ser111 |
human |
Parkinson's disease (PD) |
HEK293 |
PINK1 |
modulate |
4.0 |
26471730 |
acc3331 |
Rab8B |
phosphorylation |
Ser111 |
human |
Parkinson's disease (PD) |
HEK293 |
PINK1 |
modulate |
4.0 |
26471730 |
acc3332 |
c-Met |
phosphorylation |
Tyr1234 |
human |
prostate cancer |
DU145 |
Isothiocyanatostilbenes |
modulate |
4.0 |
26543230 |
acc3333 |
c-Met |
phosphorylation |
Tyr1235 |
human |
prostate cancer |
DU145 |
Isothiocyanatostilbenes |
modulate |
4.0 |
26543230 |
acc3334 |
GluA1 |
phosphorylation |
Ser845 |
mouse |
pain |
|
IEM1460 |
modulate |
4.0 |
26585043 |
acc3335 |
A20 |
phosphorylation |
Ser381 |
mouse |
Inflammatory diseases |
|
TNF |
modulate |
4.0 |
26649818 |
acc3336 |
A20 |
phosphorylation |
Ser480 |
mouse |
Inflammatory diseases |
|
TNF |
modulate |
4.0 |
26649818 |
acc3337 |
A20 |
phosphorylation |
Ser565 |
mouse |
Inflammatory diseases |
|
TNF |
modulate |
4.0 |
26649818 |
acc3338 |
A20 |
phosphorylation |
Thr625 |
mouse |
Inflammatory diseases |
|
TNF |
modulate |
4.0 |
26649818 |
acc3339 |
TNFR1 |
ubiquitination |
Lys256 |
mouse |
Inflammatory diseases |
|
TNF |
modulate |
4.0 |
26649818 |
acc3340 |
DARPP-32 |
phosphorylation |
Thr34 |
rat |
Parkinson's disease (PD) |
|
levodopa |
modulate |
4.0 |
26893543 |
acc3341 |
RyR2 |
phosphorylation |
Ser2814 |
mouse |
heart failure (HF) |
|
Dantrolene |
no effect |
2.0 |
27318036 |
acc3342 |
RyR2 |
phosphorylation |
Ser2814 |
rabbit |
heart failure (HF) |
|
Dantrolene |
no effect |
2.0 |
27318036 |
acc3343 |
p38 MAPK |
phosphorylation |
Thr180 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3344 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3345 |
ERK1 |
phosphorylation |
Thr202 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3346 |
ERK1 |
phosphorylation |
Tyr204 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3347 |
ERK2 |
phosphorylation |
Thr185 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3348 |
ERK2 |
phosphorylation |
Tyr187 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3349 |
PDGFRbeta |
phosphorylation |
Tyr751 |
human |
cardiovascular disease |
|
uric acid |
modulate |
4.0 |
27400779 |
acc3350 |
JNK |
phosphorylation |
Tyr185 |
human |
endothelial dysfunction |
human umbilical vein endothelial cells (HUVECs) |
berberine |
modulate |
4.0 |
27478481 |
acc3351 |
JNK |
phosphorylation |
Thr183 |
human |
endothelial dysfunction |
human umbilical vein endothelial cells (HUVECs) |
berberine |
modulate |
4.0 |
27478481 |
acc3352 |
Akt |
phosphorylation |
Ser473 |
rat |
Myocardial ischemic/reperfusion injury |
H9c2 |
asiatic acid |
counteract |
4.0 |
27657024 |
acc3353 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
Myocardial ischemic/reperfusion injury |
H9c2 |
asiatic acid |
counteract |
4.0 |
27657024 |
acc3354 |
Akt |
phosphorylation |
Ser473 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3355 |
ERK |
phosphorylation |
Thr202 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3356 |
ERK |
phosphorylation |
Tyr204 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3357 |
JNK |
phosphorylation |
Thr183 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3358 |
JNK |
phosphorylation |
Tyr185 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3359 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3360 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
asthma |
|
Caffeic acid phenethyl ester (CAPE) |
modulate |
4.0 |
27746262 |
acc3361 |
STAT6 |
phosphorylation |
Tyr641 |
mouse |
Graves' disease |
|
AS1517499 |
modulate |
4.0 |
27906181 |
acc3362 |
Akt |
phosphorylation |
Ser473 |
mouse |
inflammation |
xylene-induced ear edema model |
Ig |
modulate |
4.0 |
27914361 |
acc3363 |
beta-catenin |
phosphorylation |
Tyr489 |
human |
bronchopulmonary dysplasia |
|
dasatinib |
modulate |
4.0 |
27941077 |
acc3364 |
AKT |
phosphorylation |
Thr308 |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3365 |
AKT |
phosphorylation |
Ser473 |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3366 |
GSK3beta |
phosphorylation |
Ser9 |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3367 |
PI3K |
phosphorylation |
Tyr458 |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3368 |
PI3K |
phosphorylation |
Tyr199 |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3369 |
Tau |
phosphorylation |
unclear |
human |
Alzheimer's disease (AD) |
|
cannabidiol (CBD) + Mesenchymal stem cells (MSCs) |
modulate |
4.0 |
28025562 |
acc3370 |
PP2A-C |
phosphorylation |
Tyr307 |
human |
bladder cancer |
T24T |
XIAP KO |
modulate |
4.0 |
28057023 |
acc3371 |
PP2A-C |
phosphorylation |
Tyr307 |
human |
bladder cancer |
UMUC3 |
XIAP KO |
modulate |
4.0 |
28057023 |
acc3372 |
ATM |
phosphorylation |
Ser1981 |
human |
Prostate cancer |
DU145 |
Etoposide |
modulate |
4.0 |
28387728 |
acc3373 |
H2AX |
phosphorylation |
Ser139 |
human |
Prostate cancer |
DU145 |
Etoposide |
modulate |
3.0 |
28387728 |
acc3374 |
AKT |
phosphorylation |
Thr308 |
human |
cholangiocarcinoma |
KKU-M213 |
cimetidine |
modulate |
4.0 |
28454273 |
acc3375 |
AKT |
phosphorylation |
Ser473 |
human |
infarction |
|
tBHQ |
modulate |
4.0 |
28534651 |
acc3376 |
Akt |
phosphorylation |
Ser473 |
rat |
infarction |
|
tBHQ |
modulate |
4.0 |
28534651 |
acc3377 |
AKT |
phosphorylation |
unclear |
human |
Hepatocellular carcinoma |
Bel-7402 |
ONTD |
modulate |
4.0 |
28834734 |
acc3378 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
heart failure |
|
extract of Sheng-Mai-San (ESMS) |
modulate |
4.0 |
28841143 |
acc3379 |
Drp1 |
phosphorylation |
Ser637 |
mouse |
heart failure |
|
extract of Sheng-Mai-San (ESMS) |
modulate |
4.0 |
28841143 |
acc3380 |
IGFBP-1 |
phosphorylation |
Ser98 |
human |
Hypoxia |
HepG2 |
Rapamycin + Hypoxia |
no effect |
2.0 |
29037858 |
acc3381 |
IGFBP-1 |
phosphorylation |
Ser101 |
human |
Hypoxia |
HepG2 |
Rapamycin + Hypoxia |
no effect |
2.0 |
29037858 |
acc3382 |
IGFBP-1 |
phosphorylation |
Ser119 |
human |
Hypoxia |
HepG2 |
Rapamycin + Hypoxia |
no effect |
2.0 |
29037858 |
acc3383 |
IGFBP-1 |
phosphorylation |
Ser169 |
human |
Hypoxia |
HepG2 |
Rapamycin + Hypoxia |
no effect |
2.0 |
29037858 |
acc3384 |
IGFBP-1 |
phosphorylation |
Ser174 |
human |
Hypoxia |
HepG2 |
Rapamycin + Hypoxia |
no effect |
2.0 |
29037858 |
acc3385 |
HSA |
glycosylation |
unclear |
human |
hyperglycemia |
|
tolbutamide |
decrease |
5.0 |
29258218 |
acc3386 |
HSA |
glycosylation |
unclear |
human |
hyperglycemia |
|
losartan |
decrease |
5.0 |
29258218 |
acc3387 |
hnRNPA1 |
phosphorylation |
Ser6 |
human |
colorectal cancer |
HCT116 |
S6K2 |
modulate |
3.0 |
29344170 |
acc3388 |
hnRNPA1 |
phosphorylation |
Ser6 |
human |
colon cancer |
HCT116 |
S6 kinase 2 (S6K2) |
modulate |
4.0 |
29344170 |
acc3389 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3390 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3391 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3392 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3393 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3394 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3395 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3396 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3397 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3398 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3399 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3400 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3401 |
mTOR |
phosphorylation |
Ser2448 |
human |
breast cancer |
ZR-75-1 |
Everolimus |
resist |
5.0 |
29476223 |
acc3402 |
mTOR |
phosphorylation |
Ser2448 |
human |
breast cancer |
T47D |
Everolimus |
resist |
5.0 |
29476223 |
acc3403 |
GluA1 |
phosphorylation |
Ser831 |
mouse |
pain |
|
nitroglycerin |
modulate |
4.0 |
29486167 |
acc3404 |
calpastatin |
phosphorylation |
Ser633 |
human |
glioblastoma |
U87 |
radiation |
inhibit |
4.5 |
29581866 |
acc3405 |
STAT1 |
phosphorylation |
Tyr701 |
human |
breast cancer |
SK-BR-3 |
trastuzumab |
increase |
5.0 |
29796172 |
acc3406 |
STAT1 |
phosphorylation |
Ser727 |
human |
breast cancer |
SK-BR-3 |
trastuzumab |
increase |
5.0 |
29796172 |
acc3407 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
rheumatoid arthritis |
|
licochalcone A (LCA) |
modulate |
4.0 |
29864947 |
acc3408 |
p65 |
phosphorylation |
Ser536 |
human |
rheumatoid arthritis |
|
licochalcone A (LCA) |
modulate |
4.0 |
29864947 |
acc3409 |
Akt |
phosphorylation |
Ser473 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3410 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3411 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3412 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3413 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3414 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3415 |
IkappaBalpha |
phosphorylation |
Ser36 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3416 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3417 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
inflammation |
RAW264.7 |
Solanine A |
modulate |
4.0 |
29890469 |
acc3418 |
FAK |
phosphorylation |
Tyr397 |
rat |
intracranial aneurysms (IAs) |
|
Berberine (BBR) |
modulate |
4.0 |
29899701 |
acc3419 |
p65 |
phosphorylation |
Ser536 |
human |
breast cancer |
MCF-7 |
TRAIL + BIX-01294 |
modulate |
3.0 |
29964331 |
acc3420 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
increase |
4.0 |
29964331 |
acc3421 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
increase |
4.0 |
29964331 |
acc3422 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
increase |
4.0 |
29964331 |
acc3423 |
PERK |
phosphorylation |
Thr981 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
increase |
4.0 |
29964331 |
acc3424 |
c-Jun |
phosphorylation |
Ser73 |
human |
breast cancer |
MCF-7 |
TRAIL + BIX-01294 |
modulate |
4.0 |
29964331 |
acc3425 |
c-Jun |
phosphorylation |
Ser73 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
modulate |
4.0 |
29964331 |
acc3426 |
p65 |
phosphorylation |
Ser536 |
human |
breast cancer |
MCF-7 |
BIX-01294 |
modulate |
4.0 |
29964331 |
acc3427 |
p38 |
phosphorylation |
Thr180 |
human |
breast cancer |
MCF-7 |
TRAIL + BIX-01294 |
increase |
4.5 |
29964331 |
acc3428 |
p38 |
phosphorylation |
Tyr182 |
human |
breast cancer |
MCF-7 |
TRAIL + BIX-01294 |
increase |
4.5 |
29964331 |
acc3429 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
breast cancer |
MCF-7 |
TRAIL |
increase |
4.5 |
29964331 |
acc3430 |
PERK |
phosphorylation |
Thr981 |
human |
breast cancer |
MCF-7 |
TRAIL |
increase |
4.5 |
29964331 |
acc3431 |
Smad3 |
phosphorylation |
Ser425 |
rat |
hepatic fibrosis |
hepatic stellate cells |
TF-SC |
modulate |
4.0 |
29990830 |
acc3432 |
AMPK |
phosphorylation |
Thr172 |
human |
lung cancer |
A549 |
phenformin |
decrease |
5.0 |
29991651 |
acc3433 |
AMPK |
phosphorylation |
Thr183 |
human |
lung cancer |
A549 |
phenformin |
decrease |
5.0 |
29991651 |
acc3434 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
DTX |
decrease |
5.0 |
30061946 |
acc3435 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
DTX |
modulate |
4.0 |
30061946 |
acc3436 |
BAD |
phosphorylation |
Ser112 |
human |
lung cancer |
A549 |
DTX |
modulate |
4.0 |
30061946 |
acc3437 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
lung cancer |
A549 |
DTX |
modulate |
4.0 |
30061946 |
acc3438 |
STAT1 |
phosphorylation |
Ser727 |
rat |
diabetic nephropathy |
macrophage |
active vitamin D |
modulate |
4.0 |
30478987 |
acc3439 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
human |
nephropathy |
HEK293 |
cisplatin |
suppress |
5.0 |
30564368 |
acc3440 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
rat |
nephropathy |
|
cisplatin |
suppress |
5.0 |
30564368 |
acc3441 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
memory deficit and apoptosis |
|
Nimodipine + Vitamin E |
modulate |
4.0 |
30776390 |
acc3442 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
memory deficit and apoptosis |
|
Nimodipine + Vitamin E |
modulate |
4.0 |
30776390 |
acc3443 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
memory deficit and apoptosis |
|
Nimodipine + Vitamin E |
modulate |
4.0 |
30776390 |
acc3444 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
memory deficit and apoptosis |
|
Nimodipine + Vitamin E |
modulate |
4.0 |
30776390 |
acc3445 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
Diabetic Peripheral Neuropathy (DPN) |
|
AG490 |
modulate |
4.0 |
30913399 |
acc3446 |
PFKFB3 |
phosphorylation |
Ser461 |
human |
lung cancer |
H522 |
erlotinib |
suppress |
5.0 |
31126985 |
acc3447 |
PFKFB3 |
phosphorylation |
Ser461 |
human |
lung cancer |
H1437 |
erlotinib |
suppress |
5.0 |
31126985 |
acc3448 |
PFKFB3 |
phosphorylation |
Ser461 |
human |
lung cancer |
PC9 |
erlotinib |
suppress |
5.0 |
31126985 |
acc3449 |
PFKFB3 |
phosphorylation |
Ser461 |
human |
lung cancer |
HCC827 |
erlotinib |
suppress |
5.0 |
31126985 |
acc3450 |
JNK |
phosphorylation |
Thr183 |
mouse |
osteoclastogenesis |
RAW264.7 |
ZOL |
modulate |
4.0 |
31173157 |
acc3451 |
JNK |
phosphorylation |
Tyr185 |
mouse |
osteoclastogenesis |
RAW264.7 |
ZOL |
modulate |
4.0 |
31173157 |
acc3452 |
cSrc |
phosphorylation |
Tyr527 |
human |
breast cancer |
T47D |
folic acid (FA) |
modulate |
4.0 |
31502059 |
acc3453 |
cSrc |
phosphorylation |
Tyr527 |
human |
breast cancer |
MCF-7 |
folic acid (FA) |
modulate |
4.0 |
31502059 |
acc3454 |
cSrc |
phosphorylation |
Tyr527 |
human |
breast cancer |
BT473 |
folic acid (FA) |
modulate |
4.0 |
31502059 |
acc3455 |
cSrc |
phosphorylation |
Tyr527 |
human |
breast cancer |
BT483 |
folic acid (FA) |
modulate |
4.0 |
31502059 |
acc3456 |
AR |
phosphorylation |
Tyr534 |
human |
prostate cancer |
LNCaP |
DUSP22 |
modulate |
4.0 |
31693867 |
acc3457 |
eIF4E |
phosphorylation |
Ser209 |
human |
acute myeloid leukemia(AML) |
U937 |
SEL201 |
modulate |
4.0 |
31903169 |
acc3458 |
XPF |
acetylation |
Lys911 |
human |
genome instability |
HeLa |
UV irradiation |
modulate |
3.0 |
32034146 |
acc3459 |
XPF |
acetylation |
Lys911 |
human |
genome instability |
HeLa |
mitomycin C |
modulate |
4.0 |
32034146 |
acc3460 |
S6 |
phosphorylation |
Ser236 |
human |
melanoma |
A375 |
TM |
modulate |
4.0 |
32085796 |
acc3461 |
S6 |
phosphorylation |
Ser236 |
human |
melanoma |
RPMI |
TM |
modulate |
4.0 |
32085796 |
acc3462 |
S6 |
phosphorylation |
Ser236 |
human |
melanoma |
SH4 |
TM |
modulate |
4.0 |
32085796 |
acc3463 |
S6 |
phosphorylation |
Ser240 |
human |
melanoma |
RPMI |
TM |
modulate |
4.0 |
32085796 |
acc3464 |
S6 |
phosphorylation |
Ser240 |
human |
melanoma |
SH4 |
TM |
modulate |
4.0 |
32085796 |
acc3465 |
S6 |
phosphorylation |
Ser244 |
human |
melanoma |
RPMI |
TM |
modulate |
4.0 |
32085796 |
acc3466 |
S6 |
phosphorylation |
Ser244 |
human |
melanoma |
SH4 |
TM |
modulate |
4.0 |
32085796 |
acc3467 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
Acute lung injury (ALI) |
|
KNK437 |
modulate |
4.0 |
32091104 |
acc3468 |
TBK1 |
phosphorylation |
Ser172 |
human |
Clear cell renal cell carcinoma (ccRCC) |
UMRC2 |
"TBK1 inhibitors (e.g., CMPD1)" |
modulate |
4.0 |
32127406 |
acc3469 |
Akt |
phosphorylation |
Tyr308 |
mouse |
Alzheimer's disease (AD) |
|
Maslinic acid |
modulate |
4.0 |
32133639 |
acc3470 |
CREB |
phosphorylation |
Ser133 |
mouse |
Alzheimer's disease (AD) |
|
Maslinic acid |
modulate |
4.0 |
32133639 |
acc3471 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Alzheimer's disease (AD) |
|
Maslinic acid |
modulate |
4.0 |
32133639 |
acc3472 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Alzheimer's disease (AD) |
|
Maslinic acid |
modulate |
4.0 |
32133639 |
acc3473 |
PI3K |
phosphorylation |
Tyr199 |
mouse |
Alzheimer's disease (AD) |
|
Maslinic acid |
modulate |
4.0 |
32133639 |
acc3474 |
AKT |
phosphorylation |
Ser473 |
human |
pancreatic cancer |
Mia PaCa¨C2 |
gemcitabine |
inhibit |
5.0 |
32194695 |
acc3475 |
AKT |
phosphorylation |
Ser473 |
human |
pancreatic cancer |
Panc¨C1 |
gemcitabine |
inhibit |
5.0 |
32194695 |
acc3476 |
STAT6 |
phosphorylation |
Tyr641 |
human |
atopic dermatitis(AD) |
HaCaT |
Piperine |
modulate |
4.0 |
32392825 |
acc3477 |
STAT6 |
phosphorylation |
Tyr641 |
mouse |
atopic dermatitis(AD) |
|
Piperine |
modulate |
4.0 |
32392825 |
acc3478 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3479 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3480 |
JNK |
phosphorylation |
Thr183 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3481 |
JNK |
phosphorylation |
Thr183 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3482 |
JNK |
phosphorylation |
Thr221 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3483 |
p38 |
phosphorylation |
Thr180 |
mouse |
Inflammatory bowel disease |
|
decitabine |
modulate |
4.0 |
32468024 |
acc3484 |
MEK1 |
phosphorylation |
Ser218 |
human |
sarcoma |
SK-ES-1 |
Magnolol |
modulate |
4.0 |
32509168 |
acc3485 |
MEK2 |
phosphorylation |
Ser222 |
human |
sarcoma |
SK-ES-1 |
Magnolol |
modulate |
4.0 |
32509168 |
acc3486 |
STAT3 |
phosphorylation |
Tyr705 |
human |
sarcoma |
SK-ES-1 |
Magnolol |
modulate |
4.0 |
32509168 |
acc3487 |
NLRX1 |
ubiquitination |
Lys63 |
mouse |
heart injury |
|
CYP2J2 |
modulate |
4.0 |
32574674 |
acc3488 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
abdominal aortic aneurysm (AAA) |
|
simvastatin |
modulate |
4.0 |
32617140 |
acc3489 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
abdominal aortic aneurysm (AAA) |
|
simvastatin |
modulate |
4.0 |
32617140 |
acc3490 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
abdominal aortic aneurysm (AAA) |
|
simvastatin |
modulate |
4.0 |
32617140 |
acc3491 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
abdominal aortic aneurysm (AAA) |
|
simvastatin |
modulate |
4.0 |
32617140 |
acc3492 |
IkappaBalpha |
phosphorylation |
Ser176 |
mouse |
VSV infection |
mouse peritoneal macrophages |
Cirsitakaoside |
modulate |
4.0 |
32652505 |
acc3493 |
IkappaBalpha |
phosphorylation |
Ser180 |
mouse |
VSV infection |
mouse peritoneal macrophages |
Cirsitakaoside |
modulate |
4.0 |
32652505 |
acc3494 |
p65 |
phosphorylation |
Ser536 |
mouse |
VSV infection |
mouse peritoneal macrophages |
Cirsitakaoside |
modulate |
4.0 |
32652505 |
acc3495 |
IRF3 |
Phosphorylation |
Ser396 |
mouse |
VSV infection |
mouse peritoneal macrophages |
Cirsitakaoside |
modulate |
4.0 |
32652505 |
acc3496 |
TBK1 |
Phosphorylation |
Ser172 |
mouse |
VSV infection |
mouse peritoneal macrophages |
Cirsitakaoside |
modulate |
4.0 |
32652505 |
acc3497 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MCF-7 |
D9 + MK-2206 |
modulate |
4.0 |
32678295 |
acc3498 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
T47D |
D9 + MK-2206 |
modulate |
4.0 |
32678295 |
acc3499 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF-7 |
D9 + MK-2206 |
modulate |
4.0 |
32678295 |
acc3500 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
T47D |
D9 + MK-2206 |
modulate |
4.0 |
32678295 |
acc3501 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
BCap37 |
miR-93 |
modulate |
3.0 |
32796817 |
acc3502 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3503 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3504 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3505 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3506 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3507 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3508 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3509 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3510 |
MEK1 |
phosphorylation |
Ser217 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3511 |
MEK2 |
phosphorylation |
Ser217 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3512 |
MEK1 |
phosphorylation |
Ser217 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3513 |
MEK2 |
phosphorylation |
Ser217 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3514 |
RSK2 |
phosphorylation |
SER227 |
rat |
diabetic nephropathy |
|
S-allylcysteine (SAC) |
modulate |
4.0 |
32862702 |
acc3515 |
RSK2 |
phosphorylation |
Ser227 |
rat |
diabetic nephropathy |
|
Metformin |
modulate |
4.0 |
32862702 |
acc3516 |
AMPK |
phosphorylation |
Thr183 |
rat |
colitis |
|
Xian-He-Cao-Chang-Yan formula |
modulate |
4.0 |
33164773 |
acc3517 |
AMPK |
phosphorylation |
Thr172 |
rat |
colitis |
|
Xian-He-Cao-Chang-Yan formula |
modulate |
4.0 |
33164773 |
acc3518 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549 |
PTX |
decrease |
5.0 |
33321583 |
acc3519 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
A549/Taxol |
PTX |
decrease |
5.0 |
33321583 |
acc3520 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
A549 |
PTX |
decrease |
5.0 |
33321583 |
acc3521 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
A549 |
PTX |
decrease |
5.0 |
33321583 |
acc3522 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
A549/Taxol |
PTX |
decrease |
5.0 |
33321583 |
acc3523 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
A549/Taxol |
PTX |
decrease |
5.0 |
33321583 |
acc3524 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
A549 |
PTX |
decrease |
5.0 |
33321583 |
acc3525 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
A549 |
PTX |
decrease |
5.0 |
33321583 |
acc3526 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
A549/Taxol |
PTX |
decrease |
5.0 |
33321583 |
acc3527 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
A549/Taxol |
PTX |
decrease |
5.0 |
33321583 |
acc3528 |
FOXO3a |
acetylation |
Lys271 |
mouse |
Myocardial Infarction |
H9c2 |
Mangiferin |
modulate |
4.0 |
33523605 |
acc3529 |
FOXO3a |
acetylation |
Lys290 |
mouse |
Myocardial Infarction |
H9c2 |
Mangiferin |
modulate |
4.0 |
33523605 |
acc3530 |
AKT |
phosphorylation |
Ser473 |
human |
glioblastoma |
U251 |
Paris saponin H (PSH) |
modulate |
4.0 |
33537802 |
acc3531 |
AKT |
phosphorylation |
Thr308 |
human |
glioblastoma |
U251 |
Paris saponin H (PSH) |
modulate |
4.0 |
33537802 |
acc3532 |
ERK |
phosphorylation |
Thr202 |
human |
glioblastoma |
U251 |
Paris saponin H (PSH) |
modulate |
4.0 |
33537802 |
acc3533 |
ERK |
phosphorylation |
Tyr204 |
human |
glioblastoma |
U251 |
Paris saponin H (PSH) |
modulate |
4.0 |
33537802 |
acc3534 |
AKT |
phosphorylation |
Ser473 |
human |
Infantile Hemangiomas |
HUVECs |
Propranolol |
modulate |
4.0 |
33575332 |
acc3535 |
ERK |
phosphorylation |
Thr202/Tyr204 |
human |
Infantile Hemangiomas |
HUVECs |
Propranolol |
modulate |
4.0 |
33575332 |
acc3536 |
FAK |
phosphorylation |
Tyr397 |
human |
Infantile Hemangiomas |
HUVECs |
Propranolol |
modulate |
4.0 |
33575332 |
acc3537 |
mTOR |
phosphorylation |
Ser2448 |
human |
Infantile Hemangiomas |
HUVECs |
Propranolol |
modulate |
4.0 |
33575332 |
acc3538 |
PDK4 |
ubiquitination |
unclear |
human |
acute severe ulcerative colitis (ASUC) |
|
Cyclosporine A (CsA) |
modulate |
4.0 |
33634990 |
acc3539 |
mTOR |
phosphorylation |
Ser2448 |
mouse |
cocaine memories |
|
SB-277011 |
modulate |
4.0 |
33803578 |
acc3540 |
ASK-1 |
phosphorylation |
Thr845 |
human |
glioma |
H4 |
gefitinib |
modulate |
4.0 |
33920356 |
acc3541 |
IRE1 |
phosphorylation |
Ser724 |
human |
glioma |
H4 |
gefitinib |
modulate |
4.0 |
33920356 |
acc3542 |
JNK |
phosphorylation |
Thr183 |
human |
glioma |
H4 |
gefitinib |
modulate |
4.0 |
33920356 |
acc3543 |
JNK |
phosphorylation |
Tyr185 |
human |
glioma |
H4 |
gefitinib |
modulate |
4.0 |
33920356 |
acc3544 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
Arthritis |
|
Kurarinone |
modulate |
4.0 |
33924467 |
acc3545 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
Arthritis |
|
Kurarinone |
modulate |
4.0 |
33924467 |
acc3546 |
IRF3 |
Phosphorylation |
Ser386 |
chicken |
RNA virus infection |
DF-1 |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3547 |
IRF3 |
Phosphorylation |
Ser386 |
human |
RNA virus infection |
HEK293T |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3548 |
TBK1 |
Phosphorylation |
Ser172 |
chicken |
RNA virus infection |
DF-2 |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3549 |
TBK1 |
Phosphorylation |
Ser172 |
human |
RNA virus infection |
HEK294T |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3550 |
TRAF3 |
ubiquitination |
Lys155 |
chicken |
RNA virus infection |
DF-3 |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3551 |
TRAF3 |
ubiquitination |
Lys155 |
human |
RNA virus infection |
HEK295T |
VP3 protein |
modulate |
3.0 |
33975961 |
acc3552 |
eIF4E |
phosphorylation |
Ser209 |
human |
acute myeloid leukemia(AML) |
|
Tomivosertib |
modulate |
4.0 |
34012509 |
acc3553 |
GSK3beta |
phosphorylation |
Ser9 |
C.elegans |
AD |
|
EBR + ROSC |
inhibit |
4.0 |
34386848 |
acc3554 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
thiamine deficiency |
|
thiamine + Trolox |
modulate |
4.0 |
34468817 |
acc3555 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
thiamine deficiency |
|
thiamine + Trolox |
modulate |
4.0 |
34468817 |
acc3556 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
thiamine deficiency |
|
thiamine + Trolox |
modulate |
4.0 |
34468817 |
acc3557 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
thiamine deficiency |
|
thiamine + Trolox |
modulate |
4.0 |
34468817 |
acc3558 |
SRC |
phosphorylation |
unclear |
human |
pancreas cancer |
|
Disulfiram |
modulate |
4.0 |
34471060 |
acc3559 |
SRC |
phosphorylation |
unclear |
human |
pancreas cancer |
|
Disulfiram |
modulate |
4.0 |
34471060 |
acc3560 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
colorectal adenocarcinoma |
MC38 |
PD-1 Positive |
modulate |
3.0 |
34535949 |
acc3561 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
Aseptic loosening of prosthesis (ALP) |
RAW 264.7 |
Cimifugin |
modulate |
4.0 |
34658863 |
acc3562 |
IkappaBalpha |
phosphorylation |
Ser36 |
mouse |
Aseptic loosening of prosthesis (ALP) |
RAW 264.7 |
Cimifugin |
modulate |
4.0 |
34658863 |
acc3563 |
AMPK |
phosphorylation |
Thr183 |
mouse |
Hyperlipidemia |
|
Rosmarinic Acid |
modulate |
4.0 |
34680102 |
acc3564 |
AMPK |
phosphorylation |
Thr172 |
mouse |
Hyperlipidemia |
|
Rosmarinic Acid |
modulate |
4.0 |
34680102 |
acc3565 |
cGMP |
phosphorylation |
Ser16 |
rabbit |
atherosclerotic cardiomyopathy |
|
BGP-15 |
modulate |
4.0 |
34811751 |
acc3566 |
N2B-titin |
phosphorylation |
Ser4080 |
rabbit |
atherosclerotic cardiomyopathy |
|
BGP-15 |
modulate |
4.0 |
34811751 |
acc3567 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistant |
L6 |
ALY688 |
modulate |
4.0 |
34910600 |
acc3568 |
IRS1 |
phosphorylation |
Tyr612 |
rat |
insulin resistant |
L6 |
ALY688 |
modulate |
4.0 |
34910600 |
acc3569 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
cardiomyocyte hypertrophy |
C57BL/6J mouse |
sarpogrelate |
modulate |
4.0 |
34959669 |
acc3570 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
cardiomyocyte hypertrophy |
C57BL/6J mouse |
sarpogrelate |
modulate |
4.0 |
34959669 |
acc3571 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
cardiomyocyte hypertrophy |
C57BL/6J mouse |
sarpogrelate |
modulate |
4.0 |
34959669 |
acc3572 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
cardiomyocyte hypertrophy |
C57BL/6J mouse |
sarpogrelate |
modulate |
4.0 |
34959669 |
acc3573 |
GATA4 |
phosphorylation |
Ser105 |
mouse |
cardiomyocyte hypertrophy |
C57BL/6J mouse |
sarpogrelate |
modulate |
4.0 |
34959669 |
acc3574 |
histone H3 |
acetylation |
Lys27 |
mouse |
osteosarcoma |
"MG63,U2OS" |
levobupivacaine |
modulate |
3.0 |
35333774 |
acc3575 |
Ets-1 |
phosphorylation |
Thr38 |
rat |
cardiac fibrosis |
|
spironolactone |
modulate |
4.0 |
35495592 |
acc3576 |
Smad2 |
phosphorylation |
Ser465 |
rat |
cardiac fibrosis |
|
spironolactone |
modulate |
4.0 |
35495592 |
acc3577 |
Smad2 |
phosphorylation |
Ser467 |
rat |
cardiac fibrosis |
|
spironolactone |
modulate |
4.0 |
35495592 |
acc3578 |
Smad3 |
phosphorylation |
Ser423 |
rat |
cardiac fibrosis |
|
spironolactone |
modulate |
4.0 |
35495592 |
acc3579 |
Smad3 |
phosphorylation |
Ser425 |
rat |
cardiac fibrosis |
|
spironolactone |
modulate |
4.0 |
35495592 |
acc3580 |
MIF |
acetylation |
Lys78 |
mouse |
ischemic stroke |
|
HDAC6 inhibitor + aspirin |
modulate |
4.0 |
35585040 |
acc3581 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
colitis |
|
IRAK1/4 inhibitor |
modulate |
4.0 |
35699749 |
acc3582 |
ERK1 |
phosphorylation |
Thr202 |
human |
acute myeloid leukemia(AML) |
|
Venetoclax + Gilteritinib |
modulate |
4.0 |
35857899 |
acc3583 |
ERK1 |
phosphorylation |
Tyr204 |
human |
acute myeloid leukemia(AML) |
|
Venetoclax + Gilteritinib |
modulate |
4.0 |
35857899 |
acc3584 |
GSK3beta |
phosphorylation |
Ser9 |
human |
acute myeloid leukemia(AML) |
|
Venetoclax + Gilteritinib |
modulate |
4.0 |
35857899 |
acc3585 |
MCL-1 |
phosphorylation |
Ser159 |
human |
acute myeloid leukemia(AML) |
|
Venetoclax + Gilteritinib |
modulate |
4.0 |
35857899 |
acc3586 |
MCL-1 |
phosphorylation |
Thr161 |
human |
acute myeloid leukemia(AML) |
|
Venetoclax + Gilteritinib |
modulate |
4.0 |
35857899 |
acc3587 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
lung cancer |
Lewis |
Yifei sanjie Pills(YFSJ) |
modulate |
4.0 |
36045663 |
acc3588 |
mTOR |
phosphorylation |
Ser2448 |
mouse |
lung cancer |
Lewis |
DDP |
modulate |
4.0 |
36045663 |
acc3589 |
PPARgamma |
phosphorylation |
Ser273 |
mouse |
diabetic |
|
helical peptide segments from the LXXLL motif region |
no effect |
2.0 |
36057906 |
acc3590 |
Raf-1 |
phosphorylation |
Ser289 |
mouse |
heterologous desensitization |
|
delta opioid receptor |
inhibit |
5.0 |
36525124 |
acc3591 |
Raf-1 |
phosphorylation |
Ser296 |
mouse |
heterologous desensitization |
|
delta opioid receptor |
inhibit |
5.0 |
36525124 |
acc3592 |
Raf-1 |
phosphorylation |
Ser301 |
mouse |
heterologous desensitization |
|
delta opioid receptor |
inhibit |
5.0 |
36525124 |
acc3593 |
Src |
phosphorylation |
Tyr416 |
human |
glioma |
C6 |
Beauvericin |
modulate |
4.0 |
36610128 |
acc3594 |
STAT3 |
phosphorylation |
Tyr705 |
human |
glioma |
C6 |
Beauvericin |
modulate |
4.0 |
36610128 |
acc3595 |
HMGB1 |
acetylation |
Lys29 |
human |
kidney damage |
|
SRT 1720 |
modulate |
4.0 |
37216866 |
acc3596 |
HMGB1 |
acetylation |
Lys29 |
human |
kidney damage |
|
FPS¨CZM 1 |
modulate |
4.0 |
37216866 |
acc3597 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
Acute liver failure (ALF) |
|
Fluorofenidone(AKF-PD) |
modulate |
4.0 |
37224750 |
acc3598 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
Acute liver failure (ALF) |
|
Fluorofenidone(AKF-PD) |
modulate |
4.0 |
37224750 |
acc3599 |
MKK4 |
phosphorylation |
Ser257 |
mouse |
Acute liver failure (ALF) |
|
Fluorofenidone(AKF-PD) |
modulate |
4.0 |
37224750 |
acc3600 |
Akt |
phosphorylation |
Thr450 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3601 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3602 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3603 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3604 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3605 |
JNK |
phosphorylation |
Thr183 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3606 |
JNK |
phosphorylation |
Tyr185 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3607 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3608 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
colitis |
|
GPS extract |
modulate |
4.0 |
37249930 |
acc3609 |
Beta-catenin |
phosphorylation |
Ser298 |
mouse |
pigmentation |
B16F10 |
6-methylcoumarin |
modulate |
4.0 |
37299026 |
acc3610 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
pigmentation |
B16F10 |
6-methylcoumarin |
modulate |
4.0 |
37299026 |
acc3611 |
IkappaBalpha |
phosphorylation |
Ser180 |
human |
leukemia |
KBM¨C5 |
taxol |
inhibit |
5.0 |
16785236 |
acc3612 |
IKKbeta |
phosphorylation |
Ser181 |
human |
leukemia |
KBM¨C5 |
taxol |
inhibit |
5.0 |
16785236 |
acc3613 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
leukemia |
KBM¨C5 |
taxol |
inhibit |
5.0 |
16785236 |
acc3614 |
p65 |
phosphorylation |
Ser536 |
human |
leukemia |
KBM¨C5 |
taxol |
inhibit |
5.0 |
16785236 |
acc3615 |
Akt |
phosphorylation |
unclear |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3616 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3617 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3618 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3619 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3620 |
mTOR |
phosphorylation |
Ser2448 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3621 |
p38 |
Phosphorylation |
Thr180 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3622 |
p38 |
Phosphorylation |
Tyr182 |
rat |
diabetes mellitus |
|
Oleanolic acid |
modulate |
4.0 |
21254272 |
acc3623 |
AKT |
phosphorylation |
Ser473 |
human |
prostate cancer |
PC3 |
compound 8.12 |
modulate |
4.0 |
24971579 |
acc3624 |
AKT |
phosphorylation |
Ser473 |
human |
hepatocellular carcinoma |
HepG2 |
compound 8.12 |
modulate |
4.0 |
24971579 |
acc3625 |
JNK |
phosphorylation |
Ser2448 |
mouse |
lung cancer |
Lewis |
Yifei sanjie Pills(YFSJ) + DDP |
modulate |
4.0 |
36045663 |
acc3626 |
p53 |
phosphorylation |
Ser15 |
mouse |
lung cancer |
Lewis |
Yifei sanjie Pills(YFSJ) + DDP |
modulate |
4.0 |
36045663 |
acc3627 |
PKC |
phosphorylation |
unclear |
human |
colorectal adenocarcinoma |
HT29 |
Bile acids |
modulate |
4.0 |
1399121 |
acc3628 |
EGFR |
phosphorylation |
unclear |
human |
epidermal hyperplasia |
|
RG50864 + RG13022 |
modulate |
4.0 |
8562483 |
acc3629 |
IRS1 |
phosphorylation |
unclear |
rat |
obese |
|
captopril |
modulate |
4.0 |
9801794 |
acc3630 |
myosin light chain 20 |
phosphorylation |
Thr18 |
human |
subarachnoid hemorrhage-related vasospasm |
aortic SMCs |
Fasudil |
modulate |
4.0 |
10448094 |
acc3631 |
myosin light chain 20 |
phosphorylation |
Ser19 |
human |
subarachnoid hemorrhage-related vasospasm |
aortic SMCs |
Fasudil |
modulate |
4.0 |
10448094 |
acc3632 |
myosin light chain 20 |
phosphorylation |
Thr18 |
rabbit |
subarachnoid hemorrhage-related vasospasm |
SM-3 |
Fasudil |
modulate |
4.0 |
10448094 |
acc3633 |
myosin light chain 20 |
phosphorylation |
Ser19 |
rabbit |
subarachnoid hemorrhage-related vasospasm |
SM-4 |
Fasudil |
modulate |
4.0 |
10448094 |
acc3634 |
c-Jun |
phosphorylation |
Ser63 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3635 |
c-Jun |
phosphorylation |
Ser63 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3636 |
JNK |
phosphorylation |
Thr183 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3637 |
JNK |
phosphorylation |
Tyr185 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3638 |
JNK |
phosphorylation |
Thr183 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3639 |
JNK |
phosphorylation |
Tyr185 |
human |
asthma |
|
prednisolone |
modulate |
4.0 |
10482829 |
acc3640 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
alcoholic liver disease |
|
ethanol |
modulate |
4.0 |
10486586 |
acc3641 |
STAT3 |
phosphorylation |
Ser727 |
rat |
alcoholic liver disease |
|
ethanol |
modulate |
4.0 |
10486586 |
acc3642 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
vascular injury |
VSMCs |
Bradykinin |
modulate |
4.0 |
10775566 |
acc3643 |
ERK2 |
phosphorylation |
Thr187 |
rat |
vascular injury |
VSMCs |
Bradykinin |
modulate |
4.0 |
10775566 |
acc3644 |
Bcl-2 |
phosphorylation |
ser70 |
human |
pancreatic carcinoma |
AsPC¨C1 |
medroxyprogesterone acetate (MPA) |
modulate |
4.0 |
10813710 |
acc3645 |
Bcl-2 |
phosphorylation |
ser70 |
human |
pancreatic carcinoma |
Capan¨C2 |
medroxyprogesterone acetate (MPA) |
modulate |
4.0 |
10813710 |
acc3646 |
Bcl-2 |
phosphorylation |
ser70 |
human |
pancreatic carcinoma |
MiaPaCa¨C2 |
medroxyprogesterone acetate (MPA) |
modulate |
4.0 |
10813710 |
acc3647 |
pRb |
phosphorylation |
Ser249 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3648 |
pRb |
phosphorylation |
Thr252 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3649 |
pRb |
phosphorylation |
Thr373 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3650 |
pRb |
phosphorylation |
Ser780 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3651 |
pRb |
phosphorylation |
Ser807 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3652 |
pRb |
phosphorylation |
Ser811 |
human |
myeloid leukemia |
MV4-11 |
Transforming growth factor beta |
no effect |
2.0 |
11027571 |
acc3653 |
Rhodopsin |
Phosphorylation |
unclear |
Rat |
Retinal dysfunction |
|
Nilvadipine |
modulate |
4.0 |
11581204 |
acc3654 |
Akt |
phosphorylation |
Ser473 |
mouse |
pancreatic cancer |
|
Gemcitabine |
inhibit |
5.0 |
11595724 |
acc3655 |
Akt |
phosphorylation |
Thr308 |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3656 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3657 |
GSK3alpha |
phosphorylation |
Ser21 |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3658 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3659 |
IRS2 |
phosphorylation |
Tyr |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3660 |
p52(Shc) |
phosphorylation |
Tyr |
rat |
diabetic heart disease |
|
islet-transplanted |
modulate |
3.0 |
11723053 |
acc3661 |
Akt |
phosphorylation |
Thr308 |
rat |
diabetic |
|
islet transplantation |
modulate |
3.0 |
11723053 |
acc3662 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
islet transplantation |
modulate |
3.0 |
11723053 |
acc3663 |
GSK3alpha |
phosphorylation |
Ser9 |
rat |
diabetic |
|
islet transplantation |
modulate |
3.0 |
11723053 |
acc3664 |
GSK3beta |
phosphorylation |
Ser21 |
rat |
diabetic |
|
islet transplantation |
modulate |
3.0 |
11723053 |
acc3665 |
IRS1 |
phosphorylation |
Tyr612 |
rat |
diabetic |
|
islet transplantation |
modulate |
3.0 |
11723053 |
acc3666 |
MSH2 |
phosphorylation |
unclear |
human |
Repair of DNA damage |
HeLa-MR |
|
modulate |
2.0 |
11972333 |
acc3667 |
MSH3 |
phosphorylation |
unclear |
human |
Repair of DNA damage |
HeLa-MR |
|
modulate |
2.0 |
11972333 |
acc3668 |
Akt |
phosphorylation |
Thr308 |
rat |
obese |
|
rosiglitazone |
modulate |
4.0 |
12145152 |
acc3669 |
Akt |
phosphorylation |
Thr308 |
rat |
obese |
|
PPARgamma agonist |
modulate |
4.0 |
12145152 |
acc3670 |
CREB |
phosphorylation |
Ser133 |
mouse |
embryonic palatal issue |
MEPM cells |
forskolin |
modulate |
3.0 |
12175701 |
acc3671 |
Bcl-2 |
phosphorylation |
unclear |
human |
apoptosis |
|
H1-A |
modulate |
4.0 |
12518171 |
acc3672 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
epidermoid carcinoma |
A431/CDDP2 |
paclitaxel + cisplatin |
modulate |
4.0 |
12709826 |
acc3673 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
epidermoid carcinoma |
A431/CDDP2 |
cisplatin |
inhibit |
5.0 |
12709826 |
acc3674 |
IRS1 |
phosphorylation |
Tyr612 |
human |
diabetes mellitus |
|
Weight loss |
modulate |
3.0 |
12882908 |
acc3675 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
hyperalgesia |
|
|
modulate |
4.0 |
12941468 |
acc3676 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
hyperalgesia |
|
|
modulate |
4.0 |
12941468 |
acc3677 |
Bcl-2 |
phosphorylation |
Ser87 |
rat |
neuronal death |
|
kainic acid |
modulate |
4.0 |
12956712 |
acc3678 |
Akt |
phosphorylation |
Ser473 |
rat |
obese |
|
losartan |
modulate |
4.0 |
12960006 |
acc3679 |
Akt |
phosphorylation |
Ser473 |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3680 |
CK2 |
phosphorylation |
unclear |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3681 |
CREB |
phosphorylation |
Ser133 |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3682 |
PTEN |
phosphorylation |
Ser380 |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3683 |
PTEN |
phosphorylation |
Thr382 |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3684 |
PTEN |
phosphorylation |
Thr383 |
rat |
neuronal damage |
|
cilostazol |
modulate |
4.0 |
14634032 |
acc3685 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
SMMC-7721 |
TGF-beta1 |
modulate |
4.0 |
14637150 |
acc3686 |
AKT |
phosphorylation |
Thr308 |
human |
Hepatocellular carcinoma |
SMMC-7721 |
TGF-beta1 |
modulate |
4.0 |
14637150 |
acc3687 |
FAK |
phosphorylation |
Tyr |
human |
Hepatocellular carcinoma |
SMMC-7721 |
TGF-beta1 |
modulate |
4.0 |
14637150 |
acc3688 |
NOS3 |
phosphorylation |
Ser1179 |
rat |
"endothelial dysfunction, hypertension" |
|
DOCA¨Csalt |
modulate |
4.0 |
14993198 |
acc3689 |
NOS3 |
phosphorylation |
Ser635 |
rat |
"endothelial dysfunction, hypertension" |
|
DOCA¨Csalt |
modulate |
4.0 |
14993198 |
acc3690 |
AKT |
phosphorylation |
Ser473 |
human |
obese |
|
insulin |
modulate |
4.0 |
15010337 |
acc3691 |
ERK |
phosphorylation |
Thr202 |
rat |
Cardiac hypertrophy |
|
pertussis toxin (PTX) |
modulate |
4.0 |
15081308 |
acc3692 |
ERK |
phosphorylation |
Tyr204 |
rat |
Cardiac hypertrophy |
|
pertussis toxin (PTX) |
modulate |
4.0 |
15081308 |
acc3693 |
Mdm2 |
phosphorylation |
Ser166 |
mouse |
tumorigenesis |
mouse embryonic fibroblasts |
PKB |
modulate |
2.0 |
15169778 |
acc3694 |
Mdm2 |
phosphorylation |
Ser188 |
mouse |
tumorigenesis |
mouse embryonic fibroblasts |
PKB |
modulate |
2.0 |
15169778 |
acc3695 |
Mdm2 |
ubiquitination |
unclear |
mouse |
tumorigenesis |
mouse embryonic fibroblasts |
PKB |
modulate |
2.0 |
15169778 |
acc3696 |
PKC delta |
phosphorylation |
Thr505 |
mouse |
allergic response |
Lyn(-/-) BMMCs |
Lyn KO |
modulate |
3.0 |
15210764 |
acc3697 |
SHIP |
phosphorylation |
Tyr1020 |
mouse |
allergic response |
Lyn(-/-) BMMCs |
Lyn KO |
modulate |
3.0 |
15210764 |
acc3698 |
p38 MAPK |
phosphorylation |
unclear |
human |
airway smooth muscle (ASM) hyperplasia |
|
SB 203580 |
modulate |
4.0 |
15249425 |
acc3699 |
pRb |
phosphorylation |
Ser780 |
human |
airway smooth muscle (ASM) hyperplasia |
|
SB 203580 |
modulate |
4.0 |
15249425 |
acc3700 |
FAK |
phosphorylation |
Tyr397 |
mouse |
Hyperosmotic stress |
Swiss 3T3 |
sucrose |
modulate |
4.0 |
15302877 |
acc3701 |
FAK |
phosphorylation |
Tyr397 |
mouse |
Hyperosmotic stress |
Swiss 3T3 |
sorbitol |
modulate |
4.0 |
15302877 |
acc3702 |
FAK |
phosphorylation |
Tyr577 |
mouse |
Hyperosmotic stress |
Swiss 3T3 |
sucrose |
modulate |
4.0 |
15302877 |
acc3703 |
FAK |
phosphorylation |
Tyr577 |
mouse |
Hyperosmotic stress |
Swiss 3T3 |
sorbitol |
modulate |
4.0 |
15302877 |
acc3704 |
ERK1 |
phosphorylation |
unclear |
mouse |
Polycystic Kidney Disease |
|
OPC31260 |
modulate |
4.0 |
15361692 |
acc3705 |
ERK1 |
phosphorylation |
unclear |
rat |
Polycystic Kidney Disease |
|
OPC31260 |
modulate |
4.0 |
15361692 |
acc3706 |
Akt |
phosphorylation |
|
rat |
myocardial ischemic injury |
|
dehydroascorbic acid (DHA) |
modulate |
4.0 |
15454281 |
acc3707 |
Jak2 |
phosphorylation |
unclear |
rat |
myocardial ischemic injury |
|
dehydroascorbic acid (DHA) |
modulate |
4.0 |
15454281 |
acc3708 |
STAT1 |
phosphorylation |
unclear |
rat |
myocardial ischemic injury |
|
dehydroascorbic acid (DHA) |
modulate |
4.0 |
15454281 |
acc3709 |
STAT3 |
phosphorylation |
unclear |
rat |
myocardial ischemic injury |
|
dehydroascorbic acid (DHA) |
modulate |
4.0 |
15454281 |
acc3710 |
STAT5b |
phosphorylation |
unclear |
rat |
myocardial ischemic injury |
|
dehydroascorbic acid (DHA) |
modulate |
4.0 |
15454281 |
acc3711 |
p38 MAP kinase |
phosphorylation |
Thr180 |
rat |
cardiac myocyte dysfunction |
|
SB-203580 |
modulate |
4.0 |
15465893 |
acc3712 |
p38 MAP kinase |
phosphorylation |
Tyr182 |
rat |
cardiac myocyte dysfunction |
|
SB-203580 |
modulate |
4.0 |
15465893 |
acc3713 |
MLC20 |
phosphorylation |
unclear |
rat |
tumor |
smooth muscle cell |
nicotinamide |
no effect |
2.0 |
15559762 |
acc3714 |
ERK1 |
phosphorylation |
Thr202 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3715 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3716 |
ERK2 |
phosphorylation |
Thr185 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3717 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3718 |
p38 MAPK |
phosphorylation |
Thr180 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3719 |
p38 MAPK |
phosphorylation |
Tyr182 |
rat |
cell death |
H9c2 |
Rottlerin |
modulate |
4.0 |
15631696 |
acc3720 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetes |
Zucker diabetic Fatty rat |
cardiac insulin |
modulate |
4.0 |
15677515 |
acc3721 |
eIF2alpha |
Phosphorylation |
Ser51 |
Hamster |
Viral infection |
BHK |
Thapsigargin |
modulate |
4.0 |
15705563 |
acc3722 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
Viral infection |
MEF |
Thapsigargin |
modulate |
4.0 |
15705563 |
acc3723 |
nNOS |
phosphorylation |
Ser847 |
mouse |
obese |
|
MPTP |
modulate |
4.0 |
15721991 |
acc3724 |
H2AX |
phosphorylation |
unclear |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
3.0 |
15781651 |
acc3725 |
BAD |
phosphorylation |
Ser112 |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
4.0 |
15781651 |
acc3726 |
ERK1 |
phosphorylation |
Thr202 |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
4.0 |
15781651 |
acc3727 |
ERK1 |
phosphorylation |
Tyr204 |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
4.0 |
15781651 |
acc3728 |
ERK2 |
phosphorylation |
Thr185 |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
4.0 |
15781651 |
acc3729 |
ERK2 |
phosphorylation |
Tyr187 |
human |
tumor apoptosis |
IGROV-1 |
ST1926+ZD1839 |
modulate |
4.0 |
15781651 |
acc3730 |
IRS1 |
phosphorylation |
Ser307 |
rat |
obese |
|
rosiglitazone |
modulate |
4.0 |
15787606 |
acc3731 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreatic cancer |
PK - 1 |
PD98059 |
modulate |
4.0 |
15896303 |
acc3732 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreatic cancer |
PK - 1 |
U0126 |
modulate |
4.0 |
15896303 |
acc3733 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreatic cancer |
PK - 1 |
PD98059 |
modulate |
4.0 |
15896303 |
acc3734 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreatic cancer |
PK - 1 |
U0126 |
modulate |
4.0 |
15896303 |
acc3735 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreatic cancer |
PK - 1 |
PD98059 |
modulate |
4.0 |
15896303 |
acc3736 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreatic cancer |
PK - 1 |
U0126 |
modulate |
4.0 |
15896303 |
acc3737 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreatic cancer |
PK - 1 |
PD98059 |
modulate |
4.0 |
15896303 |
acc3738 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreatic cancer |
PK - 1 |
U0126 |
modulate |
4.0 |
15896303 |
acc3739 |
EGFR |
phosphorylation |
unclear |
human |
High glucose |
|
PKI166 |
modulate |
4.0 |
16105029 |
acc3740 |
EGFR |
phosphorylation |
unclear |
rat |
High glucose |
|
PKI166 |
modulate |
4.0 |
16105029 |
acc3741 |
MYPT1 |
phosphorylation |
Thr696 |
rat |
Pulmonary hypertension |
|
sildenafil |
modulate |
4.0 |
16205723 |
acc3742 |
MYPT1 |
phosphorylation |
Thr696 |
rat |
Pulmonary hypertension |
|
fasudil |
modulate |
4.0 |
16205723 |
acc3743 |
Rac |
prenylation |
unclear |
human |
diabetic retinopathy |
|
minodronate |
modulate |
4.0 |
16216433 |
acc3744 |
EGFR |
phosphorylation |
unclear |
rat |
diabetic |
|
ABT-627 |
modulate |
4.0 |
16239374 |
acc3745 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
morphine dependence and naloxone-induced withdrawal |
|
U0126 |
modulate |
4.0 |
16289800 |
acc3746 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
morphine dependence and naloxone-induced withdrawal |
|
U0126 |
modulate |
4.0 |
16289800 |
acc3747 |
p38 MAPK |
phosphorylation |
Thr180 |
bovine |
vascular calcification |
ţѪ¹Ü¸Æ»¯Ï¸°ûϵCVCs |
N-3Ö¬·¾ËᣨDHA£© |
modulate |
4.0 |
16514067 |
acc3748 |
p38 MAPK |
phosphorylation |
Tyr182 |
bovine |
vascular calcification |
ţѪ¹Ü¸Æ»¯Ï¸°ûϵCVCs |
N-3Ö¬·¾ËᣨDHA£© |
modulate |
4.0 |
16514067 |
acc3749 |
CREB |
phosphorylation |
Ser133 |
rat |
cognitive impairment |
|
cilostazol |
modulate |
4.0 |
16645134 |
acc3750 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
cognitive impairment |
|
huperzine A |
modulate |
4.0 |
16687166 |
acc3751 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
cognitive impairment |
|
huperzine A |
modulate |
4.0 |
16687166 |
acc3752 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
cognitive impairment |
|
huperzine A |
modulate |
4.0 |
16687166 |
acc3753 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
cognitive impairment |
|
huperzine A |
modulate |
4.0 |
16687166 |
acc3754 |
Tau |
phosphorylation |
Ser202 |
human |
Alzheimer's disease (AD) |
|
Troglitazone |
modulate |
4.0 |
16787414 |
acc3755 |
Tau |
phosphorylation |
Ser396 |
human |
Alzheimer's disease (AD) |
|
Troglitazone |
modulate |
4.0 |
16787414 |
acc3756 |
Tau |
phosphorylation |
Ser404 |
human |
Alzheimer's disease (AD) |
|
Troglitazone |
modulate |
4.0 |
16787414 |
acc3757 |
ACC1 |
phosphorylation |
Ser79 |
mouse |
atherosclerosis |
|
S17834 |
modulate |
4.0 |
16873680 |
acc3758 |
ACC2 |
phosphorylation |
Ser221 |
mouse |
atherosclerosis |
|
S17834 |
modulate |
4.0 |
16873680 |
acc3759 |
AMPK |
phosphorylation |
Thr183 |
mouse |
atherosclerosis |
|
S17834 |
modulate |
4.0 |
16873680 |
acc3760 |
AMPK |
phosphorylation |
Thr172 |
mouse |
atherosclerosis |
|
S17834 |
modulate |
4.0 |
16873680 |
acc3761 |
nNOS |
phosphorylation |
Ser847 |
human |
Brain nitric oxide regulation |
HEK-293 |
EGF |
modulate |
2.0 |
16984226 |
acc3762 |
nNOS |
phosphorylation |
Ser847 |
rat |
Brain nitric oxide regulation |
GH3 |
EGF |
modulate |
2.0 |
16984226 |
acc3763 |
Akt |
Phosphorylation |
Ser473 |
rabbit |
Myocardial infarction |
|
DADLE/Bradykinin |
modulate |
4.0 |
17292392 |
acc3764 |
ERK1 |
Phosphorylation |
Thr202 |
rabbit |
Myocardial infarction |
|
DADLE/Bradykinin |
modulate |
4.0 |
17292392 |
acc3765 |
ERK1 |
Phosphorylation |
Thr204 |
rabbit |
Myocardial infarction |
|
DADLE/Bradykinin |
modulate |
4.0 |
17292392 |
acc3766 |
AKT |
phosphorylation |
Ser473 |
human |
sarcoma |
|
rapamycin |
modulate |
4.0 |
17336708 |
acc3767 |
P70S6K |
phosphorylation |
Ser411 |
human |
sarcoma |
|
rapamycin |
modulate |
4.0 |
17336708 |
acc3768 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial infarction |
|
aerobic exercise (AE) |
modulate |
3.0 |
17505785 |
acc3769 |
NR2A |
phosphorylation |
Tyr |
rat |
brain ischemia |
|
PP2 |
modulate |
4.0 |
17556100 |
acc3770 |
NOS3 |
phosphorylation |
Ser1177 |
rat |
diabetic |
|
carvedilol |
modulate |
4.0 |
17559835 |
acc3771 |
AKT |
phosphorylation |
Ser473 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3772 |
AKT |
phosphorylation |
Thr308 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3773 |
ERK1 |
phosphorylation |
Thr202 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3774 |
ERK1 |
phosphorylation |
Tyr204 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3775 |
ERK2 |
phosphorylation |
Thr185 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3776 |
ERK2 |
phosphorylation |
Tyr187 |
human |
Ovarian cancer |
"HEY, OVCA 433, SKOV-3, A-2780" |
ZD4054 |
modulate |
4.0 |
17620430 |
acc3777 |
ERK1 |
phosphorylation |
Thr202 |
rat |
cerebral damage |
|
Ketamine |
modulate |
4.0 |
17870450 |
acc3778 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
cerebral damage |
|
Ketamine |
modulate |
4.0 |
17870450 |
acc3779 |
FOXO1 |
phosphorylation |
Thr24 |
rat |
aging |
|
CR reduces insulin |
modulate |
4.0 |
17972158 |
acc3780 |
FOXO1 |
phosphorylation |
Ser256 |
rat |
aging |
|
CR reduces insulin |
modulate |
4.0 |
17972158 |
acc3781 |
p38 MAP kinase |
phosphorylation |
Thr180 |
rat |
Hyperosmotic stress |
|
sorbitol |
modulate |
4.0 |
17996851 |
acc3782 |
p38 MAP kinase |
phosphorylation |
Thr182 |
rat |
Hyperosmotic stress |
|
sorbitol |
modulate |
4.0 |
17996851 |
acc3783 |
ERK1 |
phosphorylation |
Thr202 |
human |
osteoporotic osteoblasts |
Human osteoblasts |
PD098059 |
modulate |
4.0 |
18079194 |
acc3784 |
ERK1 |
phosphorylation |
Tyr204 |
human |
osteoporotic osteoblasts |
Human osteoblasts |
PD098059 |
modulate |
4.0 |
18079194 |
acc3785 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3786 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3787 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3788 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3789 |
JNK |
phosphorylation |
Thr183 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3790 |
JNK |
phosphorylation |
Tyr185 |
mouse |
insulin resistance |
|
MKP-4 OE |
modulate |
3.0 |
18296638 |
acc3791 |
STAT1 |
phosphorylation |
Tyr701 |
human |
Glioblastoma |
T98G |
IFN-gamma + retinoid |
modulate |
4.0 |
18368485 |
acc3792 |
STAT1 |
phosphorylation |
Tyr701 |
human |
Glioblastoma |
U87MG |
IFN-gamma + retinoid |
modulate |
4.0 |
18368485 |
acc3793 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
simvastatin |
modulate |
4.0 |
18391484 |
acc3794 |
eNOS |
phosphorylation |
unclear |
rat |
hypertensive |
|
telmisartan |
modulate |
4.0 |
18437150 |
acc3795 |
MLC |
phosphorylation |
Thr18 |
rat |
hypertensive |
|
telmisartan |
modulate |
4.0 |
18437150 |
acc3796 |
MLC |
phosphorylation |
Ser19 |
rat |
hypertensive |
|
telmisartan |
modulate |
4.0 |
18437150 |
acc3797 |
p70S6K |
phosphorylation |
Thr389 |
rat |
hypertensive |
|
telmisartan |
modulate |
4.0 |
18437150 |
acc3798 |
ACC |
phosphorylation |
Ser79 |
rat |
obesity |
|
Juniperus chinensis hot water extract (JCE) |
modulate |
4.0 |
18591785 |
acc3799 |
AMPK |
phosphorylation |
Thr172 |
rat |
obesity |
|
Juniperus chinensis hot water extract (JCE) |
modulate |
4.0 |
18591785 |
acc3800 |
AMPK |
phosphorylation |
Thr183 |
rat |
obesity |
|
Juniperus chinensis hot water extract (JCE) |
modulate |
4.0 |
18591785 |
acc3801 |
Akt |
phosphorylation |
Ser473 |
rat |
Oxidative stress |
|
glucose |
modulate |
4.0 |
18599524 |
acc3802 |
tuberin |
phosphorylation |
Thr1462 |
rat |
Oxidative stress |
|
glucose |
modulate |
4.0 |
18599524 |
acc3803 |
STAT4 |
ubiquitination |
unclear |
mouse |
experimental autoimmune encephalomyelitis (EAE) |
|
Berbamine (BM) |
modulate |
4.0 |
18606704 |
acc3804 |
eNOS |
phosphorylation |
Ser1179 |
bovine |
cardiovascular diseases |
BAECs |
H2O2 |
modulate |
4.0 |
18617528 |
acc3805 |
GluR6 |
S-nitrosylation |
unclear |
rat |
cerebral ischemia |
|
Nitric oxide |
modulate |
4.0 |
18676085 |
acc3806 |
Akt |
phosphorylation |
Ser473 |
rat |
subarachnoid hemorrhage |
|
Simvastatin |
modulate |
4.0 |
18683242 |
acc3807 |
eNOS |
phosphorylation |
Ser1177 |
rat |
subarachnoid hemorrhage |
|
Simvastatin |
modulate |
4.0 |
18683242 |
acc3808 |
ACC |
phosphorylation |
Ser79 |
rat |
Hypothyroidism |
|
T3 |
no effect |
2.0 |
18703632 |
acc3809 |
AMPK |
phosphorylation |
Thr183 |
rat |
Hypothyroidism |
|
T3 |
no effect |
2.0 |
18703632 |
acc3810 |
AMPK |
phosphorylation |
Thr172 |
rat |
Hypothyroidism |
|
T3 |
no effect |
2.0 |
18703632 |
acc3811 |
ERK |
phosphorylation |
unclear |
rat |
pancreatitis |
|
PAR2-AP |
inhibit |
4.0 |
18755806 |
acc3812 |
JNK |
phosphorylation |
unclear |
rat |
pancreatitis |
|
PAR2-AP |
inhibit |
4.0 |
18755806 |
acc3813 |
ERK |
nitration |
Tyr |
rat |
gastric mucosal healing |
|
rebamipid |
modulate |
4.0 |
18787063 |
acc3814 |
ERK1 |
phosphorylation |
Thr202 |
rat |
gastric mucosal healing |
|
rebamipid |
modulate |
4.0 |
18787063 |
acc3815 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
gastric mucosal healing |
|
rebamipid |
modulate |
4.0 |
18787063 |
acc3816 |
IkappaBalpha |
phosphorylation |
unclear |
rat |
Inflammatory |
|
Troglitazone |
modulate |
4.0 |
18827362 |
acc3817 |
ERK1 |
phosphorylation |
Thr202 |
rat |
arterial calcinosis |
|
Erythrocyte-derived depressing factor (EDDF) |
modulate |
4.0 |
18992368 |
acc3818 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
arterial calcinosis |
|
Erythrocyte-derived depressing factor (EDDF) |
modulate |
4.0 |
18992368 |
acc3819 |
ERK2 |
phosphorylation |
Thr185 |
rat |
arterial calcinosis |
|
Erythrocyte-derived depressing factor (EDDF) |
modulate |
4.0 |
18992368 |
acc3820 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
arterial calcinosis |
|
Erythrocyte-derived depressing factor (EDDF) |
modulate |
4.0 |
18992368 |
acc3821 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
aortic atherosclerosis |
|
Pravastatin |
modulate |
4.0 |
19018808 |
acc3822 |
Akt |
phosphorylation |
Thr308 |
mouse |
insulin resistance |
C2C12 |
Palmitate |
modulate |
4.0 |
19047061 |
acc3823 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) |
modulate |
4.0 |
19091959 |
acc3824 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) |
modulate |
4.0 |
19091959 |
acc3825 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) + SEW2871 |
modulate |
4.0 |
19091959 |
acc3826 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) + SEW2871 |
modulate |
4.0 |
19091959 |
acc3827 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) |
modulate |
4.0 |
19091959 |
acc3828 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) |
modulate |
4.0 |
19091959 |
acc3829 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) + SEW2871 |
modulate |
4.0 |
19091959 |
acc3830 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetic |
|
Sphingosine-1-phosphate(S1P) + SEW2871 |
modulate |
4.0 |
19091959 |
acc3831 |
P38 |
phosphorylation |
Thr180 |
mouse |
neurotoxic |
BV-2 |
tBHQ |
modulate |
4.0 |
19174151 |
acc3832 |
P38 |
phosphorylation |
Tyr182 |
mouse |
neurotoxic |
BV-2 |
tBHQ |
modulate |
4.0 |
19174151 |
acc3833 |
Akt |
phosphorylation |
Ser473 |
rat |
heart insulin signaling |
|
estradiol (E2) |
modulate |
4.0 |
19226537 |
acc3834 |
IR |
phosphorylation |
Tyr |
rat |
heart insulin signaling |
|
estradiol (E2) |
modulate |
4.0 |
19226537 |
acc3835 |
AMPK |
phosphorylation |
Thr183 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3836 |
AMPK |
phosphorylation |
Thr172 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3837 |
LKB1 |
phosphorylation |
Ser428 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3838 |
mTOR |
phosphorylation |
Ser2448 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3839 |
p70S6K |
phosphorylation |
Thr421 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3840 |
p70S6K |
phosphorylation |
Ser424 |
rat |
Left ventricular hypertrophy |
|
Resveratrol |
modulate |
4.0 |
19289642 |
acc3841 |
ASK-1 |
phosphorylation |
Ser83 |
mouse |
alcoholic cardiomyopathy |
|
ALDH2 transgene |
modulate |
3.0 |
19332462 |
acc3842 |
CREB |
phosphorylation |
Ser133 |
mouse |
alcoholic cardiomyopathy |
|
ALDH2 transgene |
modulate |
3.0 |
19332462 |
acc3843 |
GATA3 |
phosphorylation |
Ser105 |
mouse |
alcoholic cardiomyopathy |
|
ALDH2 transgene |
modulate |
3.0 |
19332462 |
acc3844 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
alcoholic cardiomyopathy |
|
ALDH2 transgene |
modulate |
3.0 |
19332462 |
acc3845 |
JNK |
phosphorylation |
Thr183 |
rat |
acute kidney injury (AKI) |
|
Glutamine |
modulate |
4.0 |
19384198 |
acc3846 |
JNK |
phosphorylation |
Tyr185 |
rat |
acute kidney injury (AKI) |
|
Glutamine |
modulate |
4.0 |
19384198 |
acc3847 |
protein 14-3-3 |
phosphorylation |
Ser185 |
rat |
acute kidney injury (AKI) |
|
Glutamine |
modulate |
4.0 |
19384198 |
acc3848 |
eNOS |
phosphorylation |
Thr497 |
mouse |
cardiac function |
MT transgenic mice |
DAHP |
inhibit |
5.0 |
19398661 |
acc3849 |
STAT1 |
phosphorylation |
unclear |
mouse |
disease visceral leishmaniasis |
macrophage |
miltefosine |
modulate |
4.0 |
19454711 |
acc3850 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
endotoxic shock |
|
U0126 |
modulate |
4.0 |
19494320 |
acc3851 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
endotoxic shock |
|
U0126 |
modulate |
4.0 |
19494320 |
acc3852 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
endotoxic shock |
|
U0126 |
modulate |
4.0 |
19494320 |
acc3853 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
endotoxic shock |
|
U0126 |
modulate |
4.0 |
19494320 |
acc3854 |
MKP-1 |
phosphorylation |
Ser539 |
mouse |
endotoxic shock |
|
U0126 |
modulate |
4.0 |
19494320 |
acc3855 |
HbA1c |
glycosylation |
unclear |
rat |
diabetes mellitus |
|
dihydroxy gymnemic triacetate |
modulate |
4.0 |
19703537 |
acc3856 |
eNOS |
phosphorylation |
Ser1177 |
human |
pre-eclampsia |
SMCs |
VEGF |
modulate |
4.0 |
19909254 |
acc3857 |
NR1 |
phosphorylation |
unclear |
rat |
nociceptive behaviors |
|
N-methyl-D-aspartate |
modulate |
4.0 |
20007733 |
acc3858 |
FOXO1 |
acetylation |
Lys |
mouse |
alcoholic fatty liver |
|
Rosiglitazone |
modulate |
4.0 |
20007851 |
acc3859 |
PGC1alpha |
acetylation |
Lys |
mouse |
alcoholic fatty liver |
|
Rosiglitazone |
modulate |
4.0 |
20007851 |
acc3860 |
ACC |
phosphorylation |
Ser79 |
mouse |
alcoholic fatty liver |
|
Rosiglitazone |
modulate |
4.0 |
20007851 |
acc3861 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
alcoholic fatty liver |
|
Rosiglitazone |
modulate |
4.0 |
20007851 |
acc3862 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3863 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3864 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3865 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3866 |
IkappaBalpha |
phosphorylation |
Ser32 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3867 |
JNK |
phosphorylation |
Thr183 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3868 |
JNK |
phosphorylation |
Tyr185 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3869 |
p38 MAPK |
phosphorylation |
Thr180 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3870 |
p38 MAPK |
phosphorylation |
Tyr182 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3871 |
p65 |
phosphorylation |
Ser536 |
rat |
diabetic |
|
streptozotocin + arjunolic acid |
modulate |
4.0 |
20053369 |
acc3872 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial ischaemia/reperfusion |
|
Tanshinone IIA |
modulate |
4.0 |
20380652 |
acc3873 |
p65 |
phosphorylation |
Ser536 |
rat |
myocardial ischaemia/reperfusion |
|
Tanshinone IIA |
modulate |
4.0 |
20380652 |
acc3874 |
Akt |
phosphorylation |
unclear |
rat |
diabetic |
|
Chitosan |
modulate |
4.0 |
20397731 |
acc3875 |
AMPK |
phosphorylation |
unclear |
rat |
diabetic |
|
Chitosan |
modulate |
4.0 |
20397731 |
acc3876 |
Smad3 |
phosphorylation |
Ser423 |
rat |
diabetic kidney disease |
|
fenofibrate |
modulate |
4.0 |
20404057 |
acc3877 |
Smad3 |
phosphorylation |
Ser425 |
rat |
diabetic kidney disease |
|
fenofibrate |
modulate |
4.0 |
20404057 |
acc3878 |
cPLA2 |
phosphorylation |
unclear |
human |
"gingival inflammation,periodontal disease" |
|
Orento |
modulate |
4.0 |
20410594 |
acc3879 |
ERK |
phosphorylation |
Thr202 |
human |
"gingival inflammation,periodontal disease" |
|
Orento |
modulate |
4.0 |
20410594 |
acc3880 |
ERK |
phosphorylation |
Tyr204 |
human |
"gingival inflammation,periodontal disease" |
|
Orento |
modulate |
4.0 |
20410594 |
acc3881 |
NR2A |
phosphorylation |
Tyr |
rat |
neuronal loss |
|
PP2 |
modulate |
4.0 |
20441772 |
acc3882 |
Akt |
phosphorylation |
Ser473 |
mouse |
dilated cardiomyopathy |
|
Propylthiouracil (PTU) |
modulate |
4.0 |
20453157 |
acc3883 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
dilated cardiomyopathy |
|
Propylthiouracil (PTU) |
modulate |
4.0 |
20453157 |
acc3884 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
dilated cardiomyopathy |
|
Propylthiouracil (PTU) |
modulate |
4.0 |
20453157 |
acc3885 |
ERK1 |
phosphorylation |
Thr202 |
rat |
multiple sclerosis (MS) |
|
Dimethylfumarate (DMF) |
modulate |
4.0 |
20482831 |
acc3886 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
multiple sclerosis (MS) |
|
Dimethylfumarate (DMF) |
modulate |
4.0 |
20482831 |
acc3887 |
ERK2 |
phosphorylation |
Thr185 |
rat |
multiple sclerosis (MS) |
|
Dimethylfumarate (DMF) |
modulate |
4.0 |
20482831 |
acc3888 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
multiple sclerosis (MS) |
|
Dimethylfumarate (DMF) |
modulate |
4.0 |
20482831 |
acc3889 |
ERK1 |
phosphorylation |
Thr202 |
Rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3890 |
ERK1 |
phosphorylation |
Tyr204 |
Rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3891 |
ERK2 |
phosphorylation |
Thr185 |
Rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3892 |
ERK2 |
phosphorylation |
Tyr187 |
Rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3893 |
p38 |
phosphorylation |
Tyr180 |
rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3894 |
p38 |
Phosphorylation |
Tyr182 |
rat |
postoperative allodynia |
|
Morphine |
modulate |
4.0 |
20493931 |
acc3895 |
ERK1 |
phosphorylation |
Thr202 |
rat |
ischemic neuronal injury |
|
Monosialotetrahexosy-1 ganglioside (GM1) |
modulate |
4.0 |
20546707 |
acc3896 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
ischemic neuronal injury |
|
Monosialotetrahexosy-1 ganglioside (GM1) |
modulate |
4.0 |
20546707 |
acc3897 |
ERK2 |
phosphorylation |
Thr185 |
rat |
ischemic neuronal injury |
|
Monosialotetrahexosy-1 ganglioside (GM1) |
modulate |
4.0 |
20546707 |
acc3898 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
ischemic neuronal injury |
|
Monosialotetrahexosy-1 ganglioside (GM1) |
modulate |
4.0 |
20546707 |
acc3899 |
Chk2 |
phosphorylation |
Thr68 |
human |
colorectal cancer |
HT-29 |
fisetin + radiation |
suppress |
4.0 |
20637980 |
acc3900 |
H2AX |
phosphorylation |
Ser139 |
human |
colorectal cancer |
HT-29 |
fisetin + radiation |
suppress |
4.0 |
20637980 |
acc3901 |
PPARgamma |
phosphorylation |
Ser273 |
mouse |
obese |
|
rosiglitazone |
modulate |
4.0 |
20651683 |
acc3902 |
NR2B |
phosphorylation |
Tyr1472 |
mouse |
fear memory and social recognition |
|
Tat¨CSrc (40¨C58) |
modulate |
4.0 |
20660101 |
acc3903 |
SERCA2 |
nitration |
unclear |
rat |
endotoxemic |
|
Thaliporphine |
modulate |
4.0 |
20848273 |
acc3904 |
TAK-1 |
phosphorylation |
Ser412 |
mouse |
endotoxemic |
Raw264.7 |
Thaliporphine |
modulate |
4.0 |
20848273 |
acc3905 |
TAK-1 |
phosphorylation |
Ser412 |
rat |
endotoxemic |
H9c2 |
Thaliporphine |
modulate |
4.0 |
20848273 |
acc3906 |
Hsp27 |
phosphorylation |
unclear |
human |
Intimal hyperplasia |
A7R5 |
MK2i |
modulate |
4.0 |
20864298 |
acc3907 |
GluR6 |
phosphorylation |
Ser |
rat |
cerebral ischemia |
|
KN-93 |
modulate |
4.0 |
20888327 |
acc3908 |
GluR6 |
phosphorylation |
Ser |
rat |
cerebral ischemia |
|
MK801 |
modulate |
4.0 |
20888327 |
acc3909 |
GluR6 |
phosphorylation |
Ser |
rat |
cerebral ischemia |
|
(L-VGCC |
modulate |
4.0 |
20888327 |
acc3910 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3911 |
ERK1 |
phosphorylation |
Thr202 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3912 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3913 |
ERK2 |
phosphorylation |
Thr185 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3914 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3915 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
myocardial infarction |
|
EPO |
no effect |
2.0 |
20981553 |
acc3916 |
histone H3 |
acetylation |
Lys9 |
human |
colorectal cancer |
SW620 |
Vorinostat + Capecitabine |
modulate |
3.0 |
21045833 |
acc3917 |
histone H3 |
acetylation |
Lys14 |
human |
colorectal cancer |
SW620 |
Vorinostat + Capecitabine |
modulate |
3.0 |
21045833 |
acc3918 |
NR2B |
phosphorylation |
unclear |
rat |
changes in sensory pathway properties |
|
CYP |
modulate |
4.0 |
21106858 |
acc3919 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
asthma |
|
Florfenicol |
modulate |
4.0 |
21163707 |
acc3920 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
asthma |
|
Florfenicol |
modulate |
4.0 |
21163707 |
acc3921 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
asthma |
|
Florfenicol |
modulate |
4.0 |
21163707 |
acc3922 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
asthma |
|
Florfenicol |
modulate |
4.0 |
21163707 |
acc3923 |
GATA3 |
phosphorylation |
unclear |
mouse |
asthma |
|
Florfenicol |
modulate |
4.0 |
21163707 |
acc3924 |
ERK1 |
phosphorylation |
Thr202 |
human |
diabetes mellitus |
HL-1 |
insulin |
decrease |
5.0 |
21270272 |
acc3925 |
ERK1 |
phosphorylation |
Tyr204 |
human |
diabetes mellitus |
HL-1 |
insulin |
decrease |
5.0 |
21270272 |
acc3926 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetes mellitus |
|
insulin |
decrease |
5.0 |
21270272 |
acc3927 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetes mellitus |
|
insulin |
decrease |
5.0 |
21270272 |
acc3928 |
ERK2 |
phosphorylation |
Thr185 |
human |
diabetes mellitus |
HL-1 |
insulin |
decrease |
5.0 |
21270272 |
acc3929 |
ERK2 |
phosphorylation |
Tyr187 |
human |
diabetes mellitus |
HL-1 |
insulin |
decrease |
5.0 |
21270272 |
acc3930 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetes mellitus |
|
insulin |
decrease |
5.0 |
21270272 |
acc3931 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetes mellitus |
|
insulin |
decrease |
5.0 |
21270272 |
acc3932 |
ERK1 |
phosphorylation |
Thr202 |
human |
diabetes mellitus |
HL-1 |
H2O2 |
modulate |
4.0 |
21270272 |
acc3933 |
ERK1 |
phosphorylation |
Tyr204 |
human |
diabetes mellitus |
HL-1 |
H2O2 |
modulate |
4.0 |
21270272 |
acc3934 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetes mellitus |
|
H2O2 |
modulate |
4.0 |
21270272 |
acc3935 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetes mellitus |
|
H2O2 |
modulate |
4.0 |
21270272 |
acc3936 |
ERK2 |
phosphorylation |
Thr185 |
human |
diabetes mellitus |
HL-1 |
H2O2 |
modulate |
4.0 |
21270272 |
acc3937 |
ERK2 |
phosphorylation |
Tyr187 |
human |
diabetes mellitus |
HL-1 |
H2O2 |
modulate |
4.0 |
21270272 |
acc3938 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetes mellitus |
|
H2O2 |
modulate |
4.0 |
21270272 |
acc3939 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetes mellitus |
|
H2O2 |
modulate |
4.0 |
21270272 |
acc3940 |
NHE-1 |
phosphorylation |
Ser703 |
rat |
myocardial infarction |
|
sildenafil |
modulate |
4.0 |
21325817 |
acc3941 |
Akt |
phosphorylation |
unclear |
rat |
pulmonary arterial hypertension |
|
Ang-(1-7) |
modulate |
4.0 |
21381494 |
acc3942 |
eNOS |
phosphorylation |
Ser1177 |
rat |
pulmonary arterial hypertension |
|
Ang-(1-7) |
modulate |
4.0 |
21381494 |
acc3943 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3944 |
AKT |
phosphorylation |
Ser473 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3945 |
AKT |
phosphorylation |
Ser473 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3946 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3947 |
AKT |
phosphorylation |
Thr308 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3948 |
AKT |
phosphorylation |
Thr308 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3949 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3950 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3951 |
ERK1 |
phosphorylation |
Thr202 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3952 |
ERK1 |
phosphorylation |
Tyr204 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3953 |
ERK1 |
phosphorylation |
Thr202 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3954 |
ERK1 |
phosphorylation |
Tyr204 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3955 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3956 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MDA-MB-231 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3957 |
ERK2 |
phosphorylation |
Thr185 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3958 |
ERK2 |
phosphorylation |
Tyr187 |
human |
breast cancer |
MCF-7 |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3959 |
ERK2 |
phosphorylation |
Thr185 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3960 |
ERK2 |
phosphorylation |
Tyr187 |
human |
cervical cancer |
Hela |
Hypoxia |
modulate |
3.0 |
21642357 |
acc3961 |
ERK1 |
phosphorylation |
unclear |
mouse |
muscular dystrophy |
|
AT-1 receptor blockers (ARB) |
modulate |
4.0 |
21645240 |
acc3962 |
ERK2 |
phosphorylation |
unclear |
mouse |
muscular dystrophy |
|
AT-1 receptor blockers (ARB) |
modulate |
4.0 |
21645240 |
acc3963 |
GATA4 |
phosphorylation |
Ser105 |
rat |
systolic dysfunction |
|
PD98059 |
modulate |
4.0 |
21702924 |
acc3964 |
Akt |
phosphorylation |
unclear |
rat |
diabetic |
|
alpha-linolenic acid (ALA) |
modulate |
4.0 |
21722811 |
acc3965 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
hepatic injury |
|
IL-22 |
modulate |
4.0 |
21843953 |
acc3966 |
CaMKIIalpha |
phosphorylation |
Thr286 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3967 |
ERK1 |
phosphorylation |
Thr202 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3968 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3969 |
p38 MAP kinase |
phosphorylation |
Thr180 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3970 |
p38 MAP kinase |
phosphorylation |
Tyr182 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3971 |
p90RSK |
phosphorylation |
Thr359 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3972 |
p90RSK |
phosphorylation |
Ser363 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3973 |
TH |
phosphorylation |
Ser19 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3974 |
TH |
phosphorylation |
Ser31 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3975 |
TH |
phosphorylation |
Ser40 |
rat |
Mania-like behavior |
|
Ouabain |
modulate |
4.0 |
21871514 |
acc3976 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial infarct |
|
NAC + ALP |
modulate |
4.0 |
21912612 |
acc3977 |
AMPKalpha |
phosphorylation |
Thr172 |
rat |
myocardial infarct |
|
NAC + ALP |
modulate |
4.0 |
21912612 |
acc3978 |
eNOS |
phosphorylation |
Ser1177 |
rat |
myocardial infarct |
|
NAC + ALP |
modulate |
4.0 |
21912612 |
acc3979 |
STAT3 |
phosphorylation |
Ser727 |
rat |
myocardial infarct |
|
NAC + ALP |
modulate |
4.0 |
21912612 |
acc3980 |
Akt |
phosphorylation |
Ser473 |
mouse |
Porphyrias |
|
vanadate |
modulate |
4.0 |
22070747 |
acc3981 |
tubulin |
acetylation |
unclear |
human |
barrier dysfunction |
HPAEC |
tubacin |
modulate |
4.0 |
22074808 |
acc3982 |
tubulin |
acetylation |
unclear |
mouse |
barrier dysfunction |
HPAEC |
tubacin |
modulate |
4.0 |
22074808 |
acc3983 |
MLC |
phosphorylation |
Thr18 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3984 |
MLC |
phosphorylation |
Ser19 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3985 |
MLC |
phosphorylation |
Thr18 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3986 |
MLC |
phosphorylation |
Ser19 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3987 |
p38 |
phosphorylation |
Thr180 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3988 |
p38 |
phosphorylation |
Tyr182 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3989 |
p38 |
phosphorylation |
Thr180 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3990 |
p38 |
phosphorylation |
Tyr182 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
suppress |
5.0 |
22074808 |
acc3991 |
MLC |
phosphorylation |
Thr18 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3992 |
MLC |
phosphorylation |
Ser19 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3993 |
MLC |
phosphorylation |
Thr18 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3994 |
MLC |
phosphorylation |
Ser19 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3995 |
p38 |
phosphorylation |
Thr180 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3996 |
p38 |
phosphorylation |
Tyr182 |
human |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3997 |
p38 |
phosphorylation |
Thr180 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3998 |
p38 |
phosphorylation |
Tyr182 |
mouse |
barrier dysfunction |
HPAEC |
2-methoxyestradiol(2-ME) |
modulate |
4.0 |
22074808 |
acc3999 |
ERK |
phosphorylation |
Tyr204 |
human |
allergic reactions |
HMC-1 |
Angelica acutiloba |
modulate |
4.0 |
22129085 |
acc4000 |
JNK |
phosphorylation |
Thr183 |
human |
allergic reactions |
HMC-1 |
Angelica acutiloba |
modulate |
4.0 |
22129085 |
acc4001 |
JNK |
phosphorylation |
Tyr185 |
human |
allergic reactions |
HMC-1 |
Angelica acutiloba |
modulate |
4.0 |
22129085 |
acc4002 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
allergic reactions |
HMC-1 |
Angelica acutiloba |
modulate |
4.0 |
22129085 |
acc4003 |
ERK |
phosphorylation |
Tyr204 |
mouse |
memory retrieval |
|
Muscimol |
modulate |
4.0 |
22169949 |
acc4004 |
ERK |
phosphorylation |
Tyr204 |
mouse |
memory retrieval |
|
diazepam |
modulate |
4.0 |
22169949 |
acc4005 |
ERK |
phosphorylation |
Tyr204 |
mouse |
memory retrieval |
|
BMI |
modulate |
4.0 |
22169949 |
acc4006 |
Tau |
phosphorylation |
Ser199 |
mouse |
Alzheimer |
|
L-3-n-butylphthalide |
modulate |
4.0 |
22233765 |
acc4007 |
Tau |
phosphorylation |
Thr205 |
mouse |
Alzheimer |
|
L-3-n-butylphthalide |
modulate |
4.0 |
22233765 |
acc4008 |
Tau |
phosphorylation |
Ser396 |
mouse |
Alzheimer |
|
L-3-n-butylphthalide |
modulate |
4.0 |
22233765 |
acc4009 |
Tau |
phosphorylation |
Ser404 |
mouse |
Alzheimer |
|
L-3-n-butylphthalide |
modulate |
4.0 |
22233765 |
acc4010 |
AKT |
phosphorylation |
unclear |
human |
pancreatic cancer |
MIAPaCa-2 |
ISIR-042 |
modulate |
4.0 |
22263802 |
acc4011 |
STAT1 |
phosphorylation |
Tyr701 |
monkey |
chronic hepatitis C |
cynomolgus monkey hepatocytes |
pegIFNlambda |
modulate |
4.0 |
22280056 |
acc4012 |
Akt |
phosphorylation |
Ser473 |
rat |
hypertension |
|
ginsenoside protopanaxatriol |
modulate |
4.0 |
22380784 |
acc4013 |
eNOS |
phosphorylation |
Ser1177 |
rat |
hypertension |
|
ginsenoside protopanaxatriol |
modulate |
4.0 |
22380784 |
acc4014 |
ERK1 |
phosphorylation |
Thr202 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
promote |
4.0 |
22454147 |
acc4015 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
promote |
4.0 |
22454147 |
acc4016 |
ERK2 |
phosphorylation |
Thr185 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
promote |
4.0 |
22454147 |
acc4017 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
promote |
4.0 |
22454147 |
acc4018 |
AMPK |
phosphorylation |
Thr183 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
modulate |
4.0 |
22454147 |
acc4019 |
AMPK |
phosphorylation |
Thr172 |
rat |
Polycystic ovarian syndrome (PCOS) |
granulosa cells |
DHT |
modulate |
4.0 |
22454147 |
acc4020 |
DOR |
phosphorylation |
Thr161 |
rat |
Inflammatory pain (CFA model) |
|
Morphine |
tolerate |
5.0 |
22466129 |
acc4021 |
FOXO1 |
phosphorylation |
Ser256 |
mouse |
cognitive deficits |
|
domoic acid |
modulate |
4.0 |
22474074 |
acc4022 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
cognitive deficits |
|
domoic acid |
modulate |
4.0 |
22474074 |
acc4023 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
cognitive deficits |
|
domoic acid |
modulate |
4.0 |
22474074 |
acc4024 |
p47phox |
phosphorylation |
Ser |
mouse |
cognitive deficits |
|
domoic acid |
modulate |
4.0 |
22474074 |
acc4025 |
Akt |
phosphorylation |
Ser473 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4026 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4027 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4028 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4029 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4030 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
cardiac hypertrophy |
|
KS370 |
modulate |
4.0 |
22484506 |
acc4031 |
MnSOD |
nitration |
unclear |
mouse |
refractory wounds |
|
Ganoderma lucidum polysaccharide(Gl-PS) |
modulate |
4.0 |
22508065 |
acc4032 |
p66Shc |
phosphorylation |
Ser36 |
mouse |
refractory wounds |
|
Ganoderma lucidum polysaccharide(Gl-PS) |
modulate |
4.0 |
22508065 |
acc4033 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
painful diabetic neuropathy (PDN) |
|
MK801 |
modulate |
4.0 |
22573263 |
acc4034 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
painful diabetic neuropathy (PDN) |
|
MK801 |
modulate |
4.0 |
22573263 |
acc4035 |
NR1 |
phosphorylation |
Ser890 |
mouse |
painful diabetic neuropathy (PDN) |
|
MK801 |
modulate |
4.0 |
22573263 |
acc4036 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
GW501516ruboxistaurin |
modulate |
4.0 |
22586590 |
acc4037 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
ruboxistaurin |
modulate |
4.0 |
22586590 |
acc4038 |
FOXO3a |
phosphorylation |
Thr32 |
mouse |
diabetic |
|
GW501516ruboxistaurin |
modulate |
4.0 |
22586590 |
acc4039 |
FOXO3a |
phosphorylation |
Thr32 |
mouse |
diabetic |
|
ruboxistaurin |
modulate |
4.0 |
22586590 |
acc4040 |
ERK1 |
phosphorylation |
unclear |
rat |
myocardial fibrosis |
|
ALI |
modulate |
4.0 |
22642589 |
acc4041 |
ERK2 |
phosphorylation |
unclear |
rat |
myocardial fibrosis |
|
ALI |
modulate |
4.0 |
22642589 |
acc4042 |
ERK1 |
phosphorylation |
Thr202 |
rat |
bone loss |
MC3T3-E1 |
hydrogen water (HW) |
modulate |
3.0 |
22648000 |
acc4043 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
bone loss |
MC3T3-E1 |
hydrogen water (HW) |
modulate |
3.0 |
22648000 |
acc4044 |
ERK2 |
phosphorylation |
Thr185 |
rat |
bone loss |
MC3T3-E1 |
hydrogen water (HW) |
modulate |
3.0 |
22648000 |
acc4045 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
bone loss |
MC3T3-E1 |
hydrogen water (HW) |
modulate |
3.0 |
22648000 |
acc4046 |
PLN |
phosphorylation |
Ser16 |
rat |
cardiac diastolic dysfunction |
cardiomyocytes |
EGb761 |
modulate |
4.0 |
22693651 |
acc4047 |
PLN |
phosphorylation |
Thr17 |
rat |
cardiac diastolic dysfunction |
cardiomyocytes |
EGb761 |
modulate |
4.0 |
22693651 |
acc4048 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4049 |
EGFR |
phosphorylation |
Tyr992 |
rat |
diabetic |
|
Losartan |
modulate |
4.0 |
22720029 |
acc4050 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
diabetic |
|
Losartan |
modulate |
4.0 |
22720029 |
acc4051 |
EGFR |
phosphorylation |
Tyr1086 |
rat |
diabetic |
|
Losartan |
modulate |
4.0 |
22720029 |
acc4052 |
EGFR |
phosphorylation |
Tyr1148 |
rat |
diabetic |
|
Losartan |
modulate |
4.0 |
22720029 |
acc4053 |
EGFR |
phosphorylation |
Tyr992 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4054 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4055 |
EGFR |
phosphorylation |
Tyr1086 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4056 |
EGFR |
phosphorylation |
Tyr1148 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4057 |
ErbB2 |
phosphorylation |
Tyr877 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4058 |
ERK |
phosphorylation |
Thr202 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4059 |
ERK |
phosphorylation |
Tyr204 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4060 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4061 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4062 |
FOXO3a |
phosphorylation |
Ser253 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4063 |
p38 |
phosphorylation |
Tyr1148 |
rat |
diabetic |
|
EGF |
modulate |
4.0 |
22720029 |
acc4064 |
CREB |
phosphorylation |
Ser133 |
rat |
Chronic hyperlipidemia |
INS-1E |
kaempferol |
modulate |
4.0 |
22819546 |
acc4065 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
cardiac dysfunction |
|
Rhynchophylline |
modulate |
4.0 |
22841535 |
acc4066 |
AMPK |
phosphorylation |
Thr183 |
rat |
diabetic |
|
curcumin |
modulate |
4.0 |
22898567 |
acc4067 |
AMPK |
phosphorylation |
Thr172 |
rat |
diabetic |
|
curcumin |
modulate |
4.0 |
22898567 |
acc4068 |
MAPK |
phosphorylation |
unclear |
rat |
neuropathic allodynia |
|
JWH015 |
modulate |
4.0 |
22901764 |
acc4069 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4070 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4071 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4072 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4073 |
MEK |
phosphorylation |
Ser217 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4074 |
MEK |
phosphorylation |
Ser221 |
mouse |
pancreatitis |
|
Sulindac |
modulate |
4.0 |
22920325 |
acc4075 |
ERK |
phosphorylation |
Tyr204 |
mouse |
diabetic |
|
resveratrol + SP600125 |
modulate |
4.0 |
22933112 |
acc4076 |
ERK |
phosphorylation |
Tyr204 |
mouse |
diabetic |
|
resveratrol + SB203580 |
modulate |
4.0 |
22933112 |
acc4077 |
JNK |
phosphorylation |
Thr183 |
mouse |
diabetic |
|
resveratrol + SP600125 |
modulate |
4.0 |
22933112 |
acc4078 |
JNK |
phosphorylation |
Tyr185 |
mouse |
diabetic |
|
resveratrol + SP600125 |
modulate |
4.0 |
22933112 |
acc4079 |
JNK |
phosphorylation |
Thr183 |
mouse |
diabetic |
|
resveratrol + SB203580 |
modulate |
4.0 |
22933112 |
acc4080 |
JNK |
phosphorylation |
Tyr185 |
mouse |
diabetic |
|
resveratrol + SB203580 |
modulate |
4.0 |
22933112 |
acc4081 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
cerebral ischemia |
|
rosiglitazone |
modulate |
4.0 |
23032483 |
acc4082 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
cerebral ischemia |
|
rosiglitazone |
modulate |
4.0 |
23032483 |
acc4083 |
NR2B |
phosphorylation |
Ser1303 |
mouse |
neuronal cell death |
|
NMDA |
modulate |
4.0 |
23085545 |
acc4084 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
diabetic |
|
stromal vascular fraction(SVF) |
modulate |
4.0 |
23088258 |
acc4085 |
Akt |
phosphorylation |
Ser473 |
rat |
infarction |
|
IPost + atorvastatin |
enhance |
4.5 |
23106693 |
acc4086 |
eNOS |
phosphorylation |
Ser1177 |
rat |
infarction |
|
IPost + atorvastatin |
enhance |
4.5 |
23106693 |
acc4087 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial ischemia/reperfusion injury |
|
Danshensu |
modulate |
4.0 |
23200898 |
acc4088 |
ERK1 |
phosphorylation |
Thr202 |
rat |
myocardial ischemia/reperfusion injury |
|
Danshensu |
modulate |
4.0 |
23200898 |
acc4089 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
myocardial ischemia/reperfusion injury |
|
Danshensu |
modulate |
4.0 |
23200898 |
acc4090 |
ERK2 |
phosphorylation |
Thr185 |
rat |
myocardial ischemia/reperfusion injury |
|
Danshensu |
modulate |
4.0 |
23200898 |
acc4091 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
myocardial ischemia/reperfusion injury |
|
Danshensu |
modulate |
4.0 |
23200898 |
acc4092 |
ESR1 |
methylation |
unclear |
human |
colorectal cancer |
|
folate |
no effect |
2.0 |
23328702 |
acc4093 |
MLH1 |
methylation |
unclear |
human |
colorectal cancer |
|
folate |
no effect |
2.0 |
23328702 |
acc4094 |
CaMKIV |
phosphorylation |
unclear |
rat |
infarction |
|
Tat-NR2B9c |
modulate |
4.0 |
23363435 |
acc4095 |
CREB |
phosphorylation |
Ser133 |
rat |
infarction |
|
Tat-NR2B9c |
modulate |
4.0 |
23363435 |
acc4096 |
JNK |
phosphorylation |
Thr183 |
human |
vascular diseases |
HUVEC |
Sphingosine-1-phosphate |
modulate |
4.0 |
23381659 |
acc4097 |
JNK |
phosphorylation |
Tyr185 |
human |
vascular diseases |
HUVEC |
Sphingosine-1-phosphate |
modulate |
4.0 |
23381659 |
acc4098 |
PPARgamma |
phosphorylation |
Ser273 |
mouse |
diabetic |
|
C333H |
modulate |
4.0 |
23563593 |
acc4099 |
JNK |
phosphorylation |
Thr183 |
human |
allergic reactions |
HMC-1 |
[6]-Shogaol |
modulate |
4.0 |
23590633 |
acc4100 |
JNK |
phosphorylation |
Tyr185 |
human |
allergic reactions |
HMC-1 |
[6]-Shogaol |
modulate |
4.0 |
23590633 |
acc4101 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
human |
allergic reactions |
HMC-1 |
[6]-Shogaol |
modulate |
4.0 |
23590633 |
acc4102 |
kras |
prenylation |
unclear |
mouse |
pancreatic cancer |
P03 |
Sulindac |
modulate |
4.0 |
23689354 |
acc4103 |
Akt |
phosphorylation |
Ser473 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4104 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4105 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4106 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4107 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4108 |
JNK |
phosphorylation |
Thr183 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4109 |
JNK |
phosphorylation |
Tyr185 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4110 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4111 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4112 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
ulcerative colitis |
|
flavonoid myricitrin |
modulate |
4.0 |
23861337 |
acc4113 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Axonal degeneration |
Axonal degeneration |
Brimonidine |
modulate |
4.0 |
23928702 |
acc4114 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Axonal degeneration |
|
Brimonidine |
modulate |
4.0 |
23928702 |
acc4115 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Axonal degeneration |
|
Brimonidine |
modulate |
4.0 |
23928702 |
acc4116 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Axonal degeneration |
|
Brimonidine |
modulate |
4.0 |
23928702 |
acc4117 |
IkappaBalpha |
phosphorylation |
Ser32 |
rat |
acute lung injury |
|
rosiglitazone |
modulate |
4.0 |
23933652 |
acc4118 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
Erectile dysfunction |
|
angiopoietin-4 |
modulate |
4.0 |
23937122 |
acc4119 |
ACC |
phosphorylation |
Ser79 |
rat |
diabetes mellitus |
|
AICAR |
no effect |
2.0 |
23967267 |
acc4120 |
AMPK |
phosphorylation |
Thr172 |
rat |
diabetes mellitus |
|
AICAR |
no effect |
2.0 |
23967267 |
acc4121 |
AMPK |
phosphorylation |
Thr183 |
rat |
diabetes mellitus |
|
AICAR |
no effect |
2.0 |
23967267 |
acc4122 |
TH |
phosphorylation |
Ser40 |
rat |
fatigue |
|
Rg3 |
modulate |
4.0 |
23994341 |
acc4123 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
diabetic |
|
angiopoietin-1 |
modulate |
4.0 |
24009238 |
acc4124 |
Tie-2 |
phosphorylation |
Tyr1100 |
mouse |
diabetic |
|
angiopoietin-1 |
modulate |
4.0 |
24009238 |
acc4125 |
VEGFR2 |
phosphorylation |
Tyr951 |
mouse |
diabetic |
|
angiopoietin-1 |
modulate |
4.0 |
24009238 |
acc4126 |
STAT3 |
phosphorylation |
unclear |
mouse |
inflammatory diseases |
|
HO¨C1 |
modulate |
4.0 |
24095726 |
acc4127 |
ERK1 |
phosphorylation |
Thr202 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4128 |
ERK1 |
phosphorylation |
Tyr204 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4129 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4130 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4131 |
ERK2 |
phosphorylation |
Thr185 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4132 |
ERK2 |
phosphorylation |
Tyr187 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4133 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4134 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4135 |
p38 MAPK |
phosphorylation |
Thr180 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4136 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
diabetic peripheral neuropathy |
Schwann cell |
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4137 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4138 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
diabetic peripheral neuropathy |
|
"cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC)" |
modulate |
4.0 |
24175152 |
acc4139 |
P38 |
phosphorylation |
unclear |
mouse |
cerebral ischemic injury |
|
shikonin |
modulate |
4.0 |
24248858 |
acc4140 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4141 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4142 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4143 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4144 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4145 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4146 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4147 |
p38 |
phosphorylation |
Thr180 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4148 |
p38 |
phosphorylation |
Tyr182 |
mouse |
endotoxemic |
|
norepinephrine |
modulate |
4.0 |
24304472 |
acc4149 |
IRS1 |
phosphorylation |
Ser636 |
mouse |
diabetic |
|
Evodiamine |
modulate |
4.0 |
24391749 |
acc4150 |
IRS1 |
phosphorylation |
Ser639 |
mouse |
diabetic |
|
Evodiamine |
modulate |
4.0 |
24391749 |
acc4151 |
AMPK |
phosphorylation |
Thr183 |
rat |
obese |
|
rosiglitazone |
modulate |
4.0 |
24424059 |
acc4152 |
AMPK |
phosphorylation |
Thr172 |
rat |
obese |
|
rosiglitazone |
modulate |
4.0 |
24424059 |
acc4153 |
Akt |
phosphorylation |
unclear |
mouse |
cardiac contractile dysfunction |
|
H2S |
no effect |
2.0 |
24622975 |
acc4154 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
cardiac contractile dysfunction |
|
H2S |
no effect |
2.0 |
24622975 |
acc4155 |
PTEN |
phosphorylation |
unclear |
mouse |
cardiac contractile dysfunction |
|
H2S |
no effect |
2.0 |
24622975 |
acc4156 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Alzheimer |
|
rosiglitazone |
modulate |
4.0 |
24623782 |
acc4157 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Alzheimer |
|
rosiglitazone |
modulate |
4.0 |
24623782 |
acc4158 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Alzheimer |
|
rosiglitazone |
modulate |
4.0 |
24623782 |
acc4159 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Alzheimer |
|
rosiglitazone |
modulate |
4.0 |
24623782 |
acc4160 |
S6K |
phosphorylation |
Thr389 |
mouse |
cardiac hypertrophy |
Acsl1 £¨H-/-£©mouse |
Rapamycin |
modulate |
4.0 |
24631848 |
acc4161 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
"VO(HB(3,5-Me2pz)3)(3,5-Me2pz)(SCN)(SCNH)2" |
modulate |
4.0 |
24636761 |
acc4162 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetic |
|
"VO(HB(3,5-Me2pz)3)(3,5-Me2pz)(SCN)(SCNH)2" |
modulate |
4.0 |
24636761 |
acc4163 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetic |
|
"VO(HB(3,5-Me2pz)3)(3,5-Me2pz)(SCN)(SCNH)2" |
modulate |
4.0 |
24636761 |
acc4164 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetic |
|
"VO(HB(3,5-Me2pz)3)(3,5-Me2pz)(SCN)(SCNH)2" |
modulate |
4.0 |
24636761 |
acc4165 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetic |
|
"VO(HB(3,5-Me2pz)3)(3,5-Me2pz)(SCN)(SCNH)2" |
modulate |
4.0 |
24636761 |
acc4166 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
CMV-mediated diaphragm wasting and weakness |
|
CMV |
modulate |
3.0 |
24671708 |
acc4167 |
STAT3 |
phosphorylation |
Ser727 |
rat |
CMV-mediated diaphragm wasting and weakness |
|
CMV |
modulate |
3.0 |
24671708 |
acc4168 |
Akt |
phosphorylation |
Ser473 |
mouse |
heart mitochondrial dysfunction |
|
Tadalafil |
modulate |
4.0 |
24727492 |
acc4169 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
heart mitochondrial dysfunction |
|
Tadalafil |
modulate |
4.0 |
24727492 |
acc4170 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
heart mitochondrial dysfunction |
|
Tadalafil |
modulate |
4.0 |
24727492 |
acc4171 |
ERK1 |
phosphorylation |
Thr202 |
rat |
"mechanical allodynia, anxiety-like behavior, and cognitive impairments" |
|
U0126 |
modulate |
4.0 |
24799176 |
acc4172 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
"mechanical allodynia, anxiety-like behavior, and cognitive impairments" |
|
U0126 |
modulate |
4.0 |
24799176 |
acc4173 |
ERK2 |
phosphorylation |
Thr185 |
rat |
"mechanical allodynia, anxiety-like behavior, and cognitive impairments" |
|
U0126 |
modulate |
4.0 |
24799176 |
acc4174 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
"mechanical allodynia, anxiety-like behavior, and cognitive impairments" |
|
U0126 |
modulate |
4.0 |
24799176 |
acc4175 |
AKT |
phosphorylation |
Ser473 |
human |
gastric carcinoma |
SGC-7901 |
Rapamycin |
modulate |
4.0 |
24799956 |
acc4176 |
mTOR |
phosphorylation |
Ser2448 |
human |
gastric carcinoma |
SGC-7901 |
Rapamycin |
modulate |
4.0 |
24799956 |
acc4177 |
p70S6K |
phosphorylation |
Thr389 |
human |
gastric carcinoma |
SGC-7901 |
Rapamycin |
modulate |
4.0 |
24799956 |
acc4178 |
IP3R |
phosphorylation |
Ser1756 |
human |
allergic |
HEK293 |
homoharringtonine |
modulate |
4.0 |
24827904 |
acc4179 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
diabetic |
|
insulin |
modulate |
4.0 |
24855642 |
acc4180 |
Smad2 |
phosphorylation |
unclear |
mouse |
cardiac fibrosis |
|
serelaxin + enalapril |
modulate |
4.0 |
24866131 |
acc4181 |
Akt |
phosphorylation |
Ser473 |
rat |
myocardial ischemia reperfusion injury |
|
picroside II |
modulate |
4.0 |
24868147 |
acc4182 |
eNOS |
phosphorylation |
Ser1177 |
rat |
myocardial ischemia reperfusion injury |
|
picroside II |
modulate |
4.0 |
24868147 |
acc4183 |
Smad2 |
acetylation |
Ser465 |
mouse |
diabetic cardiomyopathy |
H9c2 |
p300 inhibitor |
modulate |
4.0 |
24886336 |
acc4184 |
Smad2 |
acetylation |
Ser467 |
mouse |
diabetic cardiomyopathy |
H9c2 |
p300 inhibitor |
modulate |
4.0 |
24886336 |
acc4185 |
Akt |
phosphorylation |
unclear |
mouse |
Ovarian cancer |
|
Thioridazine |
modulate |
4.0 |
24952635 |
acc4186 |
mTOR |
phosphorylation |
unclear |
mouse |
Ovarian cancer |
|
Thioridazine |
modulate |
4.0 |
24952635 |
acc4187 |
PDK1 |
phosphorylation |
unclear |
mouse |
Ovarian cancer |
|
Thioridazine |
modulate |
4.0 |
24952635 |
acc4188 |
VEGFR2 |
phosphorylation |
Tyr1175 |
mouse |
Ovarian cancer |
|
Thioridazine |
modulate |
4.0 |
24952635 |
acc4189 |
Sort1 |
phosphorylation |
Ser793 |
human |
obese |
HepG2 |
palmitate |
modulate |
4.0 |
24986865 |
acc4190 |
CREB |
phosphorylation |
Ser133 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4191 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4192 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4193 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4194 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4195 |
JNK |
phosphorylation |
Thr183 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4196 |
JNK |
phosphorylation |
Tyr185 |
mouse |
cognitive impairment |
|
Lotus seedpod procyanidins |
modulate |
4.0 |
25066354 |
acc4197 |
Akt |
phosphorylation |
Ser473 |
mouse |
Acute lung injury |
|
rutin |
modulate |
4.0 |
25091621 |
acc4198 |
Smad2 |
phosphorylation |
Ser465 |
rat |
cardiac fibrosis |
Cardiac fibroblasts |
curcumin |
modulate |
4.0 |
25132338 |
acc4199 |
Smad2 |
phosphorylation |
Ser467 |
rat |
cardiac fibrosis |
Cardiac fibroblasts |
curcumin |
modulate |
4.0 |
25132338 |
acc4200 |
Smad3 |
phosphorylation |
Ser423 |
rat |
cardiac fibrosis |
Cardiac fibroblasts |
curcumin |
modulate |
4.0 |
25132338 |
acc4201 |
Smad3 |
phosphorylation |
Ser425 |
rat |
cardiac fibrosis |
Cardiac fibroblasts |
curcumin |
modulate |
4.0 |
25132338 |
acc4202 |
AKT |
phosphorylation |
Ser473 |
human |
HCM |
|
YAP OE |
modulate |
3.0 |
25168380 |
acc4203 |
Akt |
phosphorylation |
Ser473 |
mouse |
HCM |
|
YAP OE |
modulate |
3.0 |
25168380 |
acc4204 |
FOXO3 |
phosphorylation |
Thr32 |
human |
HCM |
|
YAP OE |
modulate |
3.0 |
25168380 |
acc4205 |
YAP |
phosphorylation |
Ser127 |
human |
HCM |
|
YAP OE |
modulate |
3.0 |
25168380 |
acc4206 |
YAP |
phosphorylation |
Ser127 |
mouse |
HCM |
|
YAP OE |
modulate |
3.0 |
25168380 |
acc4207 |
cav-1 |
phosphorylation |
Tyr14 |
rat |
diabetic nephropathy (DN) |
|
Curcumin |
modulate |
4.0 |
25196431 |
acc4208 |
Akt |
phosphorylation |
unclear |
rat |
diabetic nephropathy |
|
lycopene |
modulate |
4.0 |
25197372 |
acc4209 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
diabetic |
|
"9H-xanthene-9-carboxylic acid {2,2,2-trichloro-1-[3-(3-nitro-phenyl)-thioureido]-ethyl}-amide (Xn)" |
modulate |
4.0 |
25250787 |
acc4210 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
diabetic |
|
"9H-xanthene-9-carboxylic acid {2,2,2-trichloro-1-[3-(3-cyano-phenyl)-thioureido]-ethyl}-amide (Xc)" |
modulate |
4.0 |
25250787 |
acc4211 |
SMAD1 |
phosphorylation |
Ser463 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4212 |
SMAD1 |
phosphorylation |
Ser465 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4213 |
SMAD5 |
phosphorylation |
Ser463 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4214 |
SMAD5 |
phosphorylation |
Ser465 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4215 |
SMAD8 |
phosphorylation |
Ser465 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4216 |
SMAD8 |
phosphorylation |
Ser467 |
mouse |
Heterotopic ossification (HO) |
|
LDN-193189 |
modulate |
4.0 |
25253675 |
acc4217 |
Akt |
phosphorylation |
unclear |
rat |
diabetic |
|
Gallic acid |
modulate |
4.0 |
25445038 |
acc4218 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
H522¡¢H23¡¢H226 |
"5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone (DHTMF)" |
modulate |
4.0 |
25446852 |
acc4219 |
mTOR |
phosphorylation |
Ser2448 |
human |
lung cancer |
H522¡¢H23¡¢H226 |
"5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone (DHTMF)" |
modulate |
4.0 |
25446852 |
acc4220 |
p70S6K |
phosphorylation |
Thr389 |
human |
lung cancer |
H522¡¢H23¡¢H226 |
"5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone (DHTMF)" |
modulate |
4.0 |
25446852 |
acc4221 |
TRPV1 |
phosphorylation |
Ser800 |
rat |
mechanical hyperalgesia |
|
DHPG |
modulate |
4.0 |
25451626 |
acc4222 |
ATM |
phosphorylation |
Ser1981 |
mouse |
fibrosis |
UUO model |
ATM KO |
modulate |
4.0 |
25480384 |
acc4223 |
ATM |
phosphorylation |
Ser1981 |
mouse |
fibrosis |
UUO model |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4224 |
ATM |
phosphorylation |
Ser1981 |
rat |
fibrosis |
HK-2 |
ATM KO |
modulate |
4.0 |
25480384 |
acc4225 |
ATM |
phosphorylation |
Ser1981 |
rat |
fibrosis |
HK-2 |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4226 |
ATM |
phosphorylation |
Ser1981 |
rat |
fibrosis |
NRK-49F |
ATM KO |
modulate |
4.0 |
25480384 |
acc4227 |
ATM |
phosphorylation |
Ser1981 |
rat |
fibrosis |
NRK-49F |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4228 |
p53 |
phosphorylation |
Ser15 |
mouse |
fibrosis |
UUO model |
ATM KO |
modulate |
4.0 |
25480384 |
acc4229 |
p53 |
phosphorylation |
Ser15 |
mouse |
fibrosis |
UUO model |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4230 |
p53 |
phosphorylation |
Ser15 |
rat |
fibrosis |
HK-2 |
ATM KO |
modulate |
4.0 |
25480384 |
acc4231 |
p53 |
phosphorylation |
Ser15 |
rat |
fibrosis |
HK-2 |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4232 |
p53 |
phosphorylation |
Ser15 |
rat |
fibrosis |
NRK-49F |
ATM KO |
modulate |
4.0 |
25480384 |
acc4233 |
p53 |
phosphorylation |
Ser15 |
rat |
fibrosis |
NRK-49F |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4234 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
fibrosis |
UUO model |
ATM KO |
modulate |
4.0 |
25480384 |
acc4235 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
fibrosis |
UUO model |
ATM KO |
modulate |
4.0 |
25480384 |
acc4236 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
fibrosis |
UUO model |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4237 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
fibrosis |
UUO model |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4238 |
Smad3 |
phosphorylation |
Ser423 |
rat |
fibrosis |
HK-2 |
ATM KO |
modulate |
4.0 |
25480384 |
acc4239 |
Smad3 |
phosphorylation |
Ser425 |
rat |
fibrosis |
HK-2 |
ATM KO |
modulate |
4.0 |
25480384 |
acc4240 |
Smad3 |
phosphorylation |
Ser423 |
rat |
fibrosis |
HK-2 |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4241 |
Smad3 |
phosphorylation |
Ser425 |
rat |
fibrosis |
NRK-49F |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4242 |
Smad3 |
phosphorylation |
Ser423 |
rat |
fibrosis |
NRK-49F |
ATM KO |
modulate |
4.0 |
25480384 |
acc4243 |
Smad3 |
phosphorylation |
Ser425 |
rat |
fibrosis |
NRK-49F |
ATM KO |
modulate |
4.0 |
25480384 |
acc4244 |
Smad3 |
phosphorylation |
Ser423 |
rat |
fibrosis |
NRK-49F |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4245 |
Smad3 |
phosphorylation |
Ser425 |
rat |
fibrosis |
NRK-49F |
KU-55933 |
modulate |
4.0 |
25480384 |
acc4246 |
IRS1 |
phosphorylation |
unclear |
rat |
diabetic |
|
nymphayol |
modulate |
4.0 |
25499137 |
acc4247 |
AMPKalpha |
phosphorylation |
Thr172 |
human |
hepatocellular carcinoma |
HepG2 |
Ursolic acid |
modulate |
4.0 |
25547067 |
acc4248 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4249 |
AKT |
phosphorylation |
Ser473 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4250 |
AMPKalpha |
phosphorylation |
Thr172 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4251 |
AMPKalpha |
phosphorylation |
Thr172 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4252 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4253 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4254 |
ERK1 |
phosphorylation |
Thr202 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4255 |
ERK1 |
phosphorylation |
Tyr204 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4256 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4257 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4258 |
ERK2 |
phosphorylation |
Thr185 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4259 |
ERK2 |
phosphorylation |
Tyr187 |
human |
lung cancer |
|
beta-elemene |
modulate |
4.0 |
25598321 |
acc4260 |
ERK1 |
phosphorylation |
Thr202 |
rat |
Obesity |
|
monosodium l-glutamate (MSG) |
modulate |
4.0 |
25683673 |
acc4261 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Obesity |
|
monosodium l-glutamate (MSG) |
modulate |
4.0 |
25683673 |
acc4262 |
ERK2 |
phosphorylation |
Thr183 |
rat |
Obesity |
|
monosodium l-glutamate (MSG) |
modulate |
4.0 |
25683673 |
acc4263 |
ERK2 |
phosphorylation |
Tyr185 |
rat |
Obesity |
|
monosodium l-glutamate (MSG) |
modulate |
4.0 |
25683673 |
acc4264 |
PDGFRbeta |
phosphorylation |
Tyr857 |
human |
gastric cancer |
GIST¨CT1 |
dasatinib |
inhibit |
5.0 |
25737303 |
acc4265 |
Akt |
phosphorylation |
Ser473 |
rat |
hypertension |
|
Magnolol |
modulate |
4.0 |
25793876 |
acc4266 |
eNOS |
phosphorylation |
Ser1179 |
rat |
hypertension |
|
Magnolol |
modulate |
4.0 |
25793876 |
acc4267 |
AKT |
phosphorylation |
Thr308 |
human |
obese |
|
Bariatric Surgery |
modulate |
3.0 |
25876175 |
acc4268 |
AKT |
phosphorylation |
Ser473 |
human |
obese |
|
Bariatric Surgery |
modulate |
3.0 |
25876175 |
acc4269 |
Akt |
phosphorylation |
Ser473 |
rat |
Hypertension-induced insulin resistance |
|
"ARB, Tempol, PDTC" |
modulate |
4.0 |
25928697 |
acc4270 |
IRS1 |
phosphorylation |
Ser612 |
rat |
Hypertension-induced insulin resistance |
|
"ARB, Tempol, PDTC" |
modulate |
4.0 |
25928697 |
acc4271 |
IkappaBalpha |
phosphorylation |
Ser32 |
rat |
Hypertension-induced insulin resistance |
|
"ARB, Tempol, PDTC" |
modulate |
4.0 |
25928697 |
acc4272 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
HepG2 |
palmitate |
modulate |
4.0 |
26039731 |
acc4273 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4274 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4275 |
eNOS |
phosphorylation |
Ser1177 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4276 |
ErbB2 |
phosphorylation |
Tyr1221 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4277 |
ErbB2 |
phosphorylation |
Tyr1222 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4278 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4279 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4280 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4281 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4282 |
FOXO3a |
phosphorylation |
Ser253 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4283 |
IkappaBalpha |
phosphorylation |
unclear |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4284 |
ROCK2 |
phosphorylation |
Tyr256 |
rat |
diabetic |
|
Lapatinib |
modulate |
4.0 |
26114862 |
acc4285 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
Irisin |
modulate |
4.0 |
26201094 |
acc4286 |
GSK3 |
phosphorylation |
Ser9 |
mouse |
diabetic |
|
Irisin |
modulate |
4.0 |
26201094 |
acc4287 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
Endothelial dysfunction |
|
l-arginine |
modulate |
4.0 |
26214584 |
acc4288 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
Endothelial dysfunction |
|
sepiapterin |
modulate |
4.0 |
26214584 |
acc4289 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
Endothelial dysfunction |
|
salsalate |
modulate |
4.0 |
26214584 |
acc4290 |
RIP3 |
S-nitrosylation |
Cys119 |
human |
neuronal damage |
SH-SY5Y |
MK801 |
modulate |
4.0 |
26319693 |
acc4291 |
AKT |
phosphorylation |
Ser473 |
human |
haemorrhagic shock |
Huh7 |
VPA |
modulate |
4.0 |
26333042 |
acc4292 |
GSK3beta |
phosphorylation |
Ser9 |
human |
haemorrhagic shock |
Huh7 |
VPA |
modulate |
4.0 |
26333042 |
acc4293 |
PTEN |
phosphorylation |
Ser380 |
human |
haemorrhagic shock |
Huh7 |
VPA |
modulate |
4.0 |
26333042 |
acc4294 |
PTEN |
phosphorylation |
Thr382 |
human |
haemorrhagic shock |
Huh7 |
VPA |
modulate |
4.0 |
26333042 |
acc4295 |
PTEN |
phosphorylation |
Ser383 |
human |
haemorrhagic shock |
Huh7 |
VPA |
modulate |
4.0 |
26333042 |
acc4296 |
AKT |
phosphorylation |
Ser473 |
human |
myeloma |
8226/AMY1 |
bortezomib |
inhibit |
5.0 |
26341959 |
acc4297 |
Akt |
phosphorylation |
Ser473 |
mouse |
breast cancer |
|
MK-2206 |
modulate |
4.0 |
26351323 |
acc4298 |
Akt |
phosphorylation |
Ser473 |
mouse |
breast cancer |
|
AZD5363 |
modulate |
4.0 |
26351323 |
acc4299 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
Myocardial ischemia reperfusion injury |
|
Remifentanil |
modulate |
4.0 |
26468894 |
acc4300 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
Myocardial ischemia reperfusion injury |
|
Remifentanil |
modulate |
4.0 |
26468894 |
acc4301 |
eNOS |
phosphorylation |
Ser1177 |
rat |
ischemia-reperfusion injury |
|
ANG¨C(1¨C7) |
modulate |
4.0 |
26519026 |
acc4302 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
mitochondrial dysfunction |
|
fasudil |
modulate |
4.0 |
26602979 |
acc4303 |
Akt |
phosphorylation |
Ser473 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4304 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4305 |
PTEN |
phosphorylation |
Ser380 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4306 |
PTEN |
phosphorylation |
Thr382 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4307 |
PTEN |
phosphorylation |
Thr383 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4308 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
MI/R (myocardial ischaemia/reperfusion) injury |
|
BpV |
modulate |
4.0 |
26666444 |
acc4309 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
peritoneal fibrosis |
|
Gefitinib |
modulate |
4.0 |
26677863 |
acc4310 |
Smad3 |
phosphorylation |
Ser423 |
rat |
peritoneal fibrosis |
|
Gefitinib |
modulate |
4.0 |
26677863 |
acc4311 |
Smad3 |
phosphorylation |
Ser425 |
rat |
peritoneal fibrosis |
|
Gefitinib |
modulate |
4.0 |
26677863 |
acc4312 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
peritoneal fibrosis |
|
Gefitinib |
modulate |
4.0 |
26677863 |
acc4313 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
corneal stroma |
|
tofacitinib |
modulate |
4.0 |
26689752 |
acc4314 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistance |
FAO |
Rapamycin |
modulate |
4.0 |
26733005 |
acc4315 |
Akt |
phosphorylation |
Thr308 |
rat |
insulin resistance |
FAO |
Rapamycin |
modulate |
4.0 |
26733005 |
acc4316 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistance |
FAO |
PF-4708671 |
modulate |
4.0 |
26733005 |
acc4317 |
Akt |
phosphorylation |
Thr308 |
rat |
insulin resistance |
FAO |
PF-4708671 |
modulate |
4.0 |
26733005 |
acc4318 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistance |
L6 |
Rapamycin |
modulate |
4.0 |
26733005 |
acc4319 |
Akt |
phosphorylation |
Thr308 |
rat |
insulin resistance |
L6 |
Rapamycin |
modulate |
4.0 |
26733005 |
acc4320 |
Akt |
phosphorylation |
Ser473 |
rat |
insulin resistance |
L6 |
PF-4708671 |
modulate |
4.0 |
26733005 |
acc4321 |
Akt |
phosphorylation |
Thr308 |
rat |
insulin resistance |
L6 |
PF-4708671 |
modulate |
4.0 |
26733005 |
acc4322 |
Akt |
phosphorylation |
Ser473 |
mouse |
diabetic |
|
Phycocyanin |
modulate |
4.0 |
26827782 |
acc4323 |
IRS1 |
phosphorylation |
Tyr612 |
mouse |
diabetic |
|
Phycocyanin |
modulate |
4.0 |
26827782 |
acc4324 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
diabetic |
|
Phycocyanin |
modulate |
4.0 |
26827782 |
acc4325 |
cav-1 |
phosphorylation |
Tyr14 |
mouse |
diabetic nephropathy |
|
curcumin |
modulate |
4.0 |
26838071 |
acc4326 |
cav-1 |
phosphorylation |
Tyr14 |
rat |
diabetic nephropathy |
podocyte |
Curcumin |
modulate |
4.0 |
26838071 |
acc4327 |
nephrin |
phosphorylation |
Tyr1176 |
mouse |
diabetic |
|
MRE¨C269 |
modulate |
4.0 |
26868296 |
acc4328 |
nephrin |
phosphorylation |
Tyr1193 |
mouse |
diabetic |
|
MRE¨C269 |
modulate |
4.0 |
26868296 |
acc4329 |
PPARgamma |
sulfhydration |
Cys139 |
mouse |
obese |
|
H2S |
modulate |
4.0 |
26946260 |
acc4330 |
ERK |
phosphorylation |
Thr202 |
mouse |
nociceptive behaviors |
|
l-alpha-aminoadipate |
modulate |
4.0 |
26948958 |
acc4331 |
ERK |
phosphorylation |
Tyr204 |
mouse |
nociceptive behaviors |
|
l-alpha-aminoadipate |
modulate |
4.0 |
26948958 |
acc4332 |
TRPA1 |
hydroxylation |
Pro394 |
human |
Dysesthesia |
HEK293 |
dimethyloxalylglycine (DMOG) |
modulate |
4.0 |
26983498 |
acc4333 |
TRPA1 |
hydroxylation |
Pro394 |
mouse |
Dysesthesia |
|
dimethyloxalylglycine (DMOG) |
modulate |
4.0 |
26983498 |
acc4334 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4335 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4336 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4337 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4338 |
JNK |
phosphorylation |
Thr183 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4339 |
JNK |
phosphorylation |
Tyr185 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4340 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4341 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
Parkinson's disease (PD) |
|
desferrioxamine (DFO) |
modulate |
4.0 |
26996132 |
acc4342 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
Iodine deficiency |
|
metformin |
modulate |
4.0 |
27035650 |
acc4343 |
p70S6K |
phosphorylation |
Thr389 |
mouse |
Iodine deficiency |
|
rapamycin |
modulate |
4.0 |
27035650 |
acc4344 |
occludin |
glycosylation |
unclear |
mouse |
diabetic brain infarct |
|
N-acetylcysteine |
modulate |
4.0 |
27083477 |
acc4345 |
eNOS |
phosphorylation |
Ser1177 |
rat |
pulmonary arterial hypertension (PAH) |
|
metformin |
modulate |
4.0 |
27084848 |
acc4346 |
CREB |
phosphorylation |
Ser133 |
human |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4347 |
CREB |
phosphorylation |
Ser133 |
mouse |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4348 |
ERK1 |
phosphorylation |
Thr202 |
human |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4349 |
ERK1 |
phosphorylation |
Tyr204 |
human |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4350 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4351 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4352 |
ERK2 |
phosphorylation |
Thr185 |
human |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4353 |
ERK2 |
phosphorylation |
Tyr187 |
human |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4354 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4355 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
atopic dermatitis |
|
Benzoxaborole Phosphodiesterase Inhibitors |
modulate |
4.0 |
27353073 |
acc4356 |
Fyn |
S-nitrosylation |
Cys498 |
rat |
cerebral ischemia |
|
GSNO |
modulate |
4.0 |
27420046 |
acc4357 |
Smad2 |
phosphorylation |
Ser465 |
mouse |
Hepatic steatosis |
|
Vaccination |
modulate |
3.0 |
27562139 |
acc4358 |
Smad2 |
phosphorylation |
Ser467 |
mouse |
Hepatic steatosis |
|
Vaccination |
modulate |
3.0 |
27562139 |
acc4359 |
NOS3 |
phosphorylation |
Ser1177 |
rat |
Endothelial dysfunction |
|
Sal B |
modulate |
4.0 |
27614127 |
acc4360 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
PSEE |
modulate |
4.0 |
27649243 |
acc4361 |
Akt |
phosphorylation |
Thr308 |
rat |
diabetic |
|
PSEE |
modulate |
4.0 |
27649243 |
acc4362 |
Akt |
phosphorylation |
Ser473 |
mouse |
obese |
|
berberine |
modulate |
4.0 |
27702567 |
acc4363 |
IKKbeta |
phosphorylation |
Ser177 |
mouse |
obese |
|
berberine |
modulate |
4.0 |
27702567 |
acc4364 |
IKKbeta |
phosphorylation |
Ser181 |
mouse |
obese |
|
berberine |
modulate |
4.0 |
27702567 |
acc4365 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
obese |
|
berberine |
modulate |
4.0 |
27702567 |
acc4366 |
JNK |
phosphorylation |
unclear |
mouse |
obese |
|
berberine |
modulate |
4.0 |
27702567 |
acc4367 |
Titin |
phosphorylation |
Ser4080 |
rat |
heart failure |
|
Spermidine |
modulate |
4.0 |
27841876 |
acc4368 |
eNOS |
nitration |
unclear |
mouse |
Hypertension |
|
Tempol |
modulate |
4.0 |
27861245 |
acc4369 |
eNOS |
Phosphorylation |
Ser1176 |
mouse |
Hypertension |
|
Tempol |
modulate |
4.0 |
27861245 |
acc4370 |
eNOS |
Phosphorylation |
Ser1179 |
mouse |
Hypertension |
|
Tempol |
modulate |
4.0 |
27861245 |
acc4371 |
eNOS |
S-glutathionylation |
unclear |
mouse |
Hypertension |
|
Tempol |
modulate |
4.0 |
27861245 |
acc4372 |
Akt |
phosphorylation |
Ser473 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4373 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4374 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4375 |
IkappaB |
phosphorylation |
Ser32 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4376 |
P38 |
phosphorylation |
Thr180 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4377 |
P38 |
phosphorylation |
Tyr182 |
mouse |
acute liver injury |
|
obeticholic acid (OCA) |
modulate |
4.0 |
27865854 |
acc4378 |
Akt |
phosphorylation |
unclear |
rat |
cerebral ischemia |
|
Wortmannin |
modulate |
4.0 |
27866373 |
acc4379 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
cerebral ischemia |
|
Wortmannin |
modulate |
4.0 |
27866373 |
acc4380 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
renal fibrosis |
|
dasatinib |
modulate |
4.0 |
27927780 |
acc4381 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
renal fibrosis |
|
dasatinib |
modulate |
4.0 |
27927780 |
acc4382 |
Akt |
phosphorylation |
unclear |
mouse |
"insulin resistance, obesity" |
|
Calorie restriction |
modulate |
3.0 |
28024145 |
acc4383 |
PTEN |
phosphorylation |
Ser380 |
mouse |
"insulin resistance, obesity" |
|
Calorie restriction |
modulate |
3.0 |
28024145 |
acc4384 |
PLC-gamma1 |
phosphorylation |
Tyr783 |
mouse |
asthma |
|
linker for activation of T cells (LAT) |
modulate |
4.0 |
28063403 |
acc4385 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
opioid dependence |
|
morphine |
modulate |
4.0 |
28082900 |
acc4386 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
opioid dependence |
|
morphine |
modulate |
4.0 |
28082900 |
acc4387 |
RyR2 |
oxidation |
unclear |
rat |
arrhythmia |
|
NS309 |
modulate |
4.0 |
28096168 |
acc4388 |
Akt |
phosphorylation |
Ser473 |
rat |
neuronal degeneration |
|
CHIP overexpression |
modulate |
3.0 |
28153090 |
acc4389 |
eIF2alpha |
phosphorylation |
Ser51 |
rat |
neuronal degeneration |
|
CHIP overexpression |
modulate |
3.0 |
28153090 |
acc4390 |
mTOR |
phosphorylation |
Ser2448 |
rat |
neuronal damage |
|
DXT |
modulate |
4.0 |
28365975 |
acc4391 |
p70S6K |
phosphorylation |
Thr389 |
rat |
neuronal damage |
|
DXT |
modulate |
4.0 |
28365975 |
acc4392 |
Tau |
phosphorylation |
Ser396 |
mouse |
diabetic |
|
Folic acid |
modulate |
4.0 |
28422052 |
acc4393 |
ERK1 |
phosphorylation |
Thr202 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4394 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4395 |
ERK2 |
phosphorylation |
Thr185 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4396 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4397 |
Smad3 |
phosphorylation |
Ser423 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4398 |
Smad3 |
phosphorylation |
Ser425 |
rat |
hyperuricemic nephropathy |
|
U0126 |
modulate |
4.0 |
28442634 |
acc4399 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
insulin |
modulate |
4.0 |
28511140 |
acc4400 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
insulin glargine U100 (Gla) |
modulate |
4.0 |
28511140 |
acc4401 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
insulin detemir (Det) |
modulate |
4.0 |
28511140 |
acc4402 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
insulin detemir (Det) |
modulate |
4.0 |
28511140 |
acc4403 |
Akt |
phosphorylation |
Thr308 |
mouse |
glucose intolerance and insulin resistance |
|
HCV infection |
modulate |
3.0 |
28559285 |
acc4404 |
Akt |
phosphorylation |
Ser473 |
mouse |
glucose intolerance and insulin resistance |
|
HCV infection |
modulate |
3.0 |
28559285 |
acc4405 |
FOXO1 |
phosphorylation |
Ser256 |
mouse |
glucose intolerance and insulin resistance |
|
HCV infection |
modulate |
3.0 |
28559285 |
acc4406 |
IRS2 |
phosphorylation |
Tyr |
mouse |
glucose intolerance and insulin resistance |
|
HCV infection |
modulate |
3.0 |
28559285 |
acc4407 |
PDK1 |
phosphorylation |
Ser241 |
mouse |
glucose intolerance and insulin resistance |
|
HCV infection |
modulate |
3.0 |
28559285 |
acc4408 |
CREB |
phosphorylation |
Ser133 |
mouse |
AD |
|
KH032 |
modulate |
4.0 |
28578486 |
acc4409 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
AD |
|
KH032 |
modulate |
4.0 |
28578486 |
acc4410 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
AD |
|
KH032 |
modulate |
4.0 |
28578486 |
acc4411 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
AD |
|
KH032 |
modulate |
4.0 |
28578486 |
acc4412 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
AD |
|
KH032 |
modulate |
4.0 |
28578486 |
acc4413 |
Nrf2 |
phosphorylation |
unclear |
human |
multiple sclerosis |
|
medical ozone |
modulate |
4.0 |
28623000 |
acc4414 |
FOXO3a |
phosphorylation |
Ser253 |
mouse |
ovarian damage |
|
melatonin and ghrelin |
modulate |
4.0 |
28658519 |
acc4415 |
FOXO3a |
phosphorylation |
Ser253 |
mouse |
ovarian damage |
|
cisplatin |
modulate |
4.0 |
28658519 |
acc4416 |
PTEN |
phosphorylation |
Ser380 |
mouse |
ovarian damage |
|
melatonin + ghrelin |
modulate |
4.0 |
28658519 |
acc4417 |
PTEN |
phosphorylation |
Ser380 |
mouse |
ovarian damage |
|
cisplatin |
modulate |
4.0 |
28658519 |
acc4418 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
mechanical allodynia and central sensitization induced by bortezomib treatment |
|
metformin |
modulate |
4.0 |
28729113 |
acc4419 |
AMPK |
phosphorylation |
Thr172 |
rat |
myocardial infarction |
H9c2 |
A-769662 |
decrease |
4.0 |
28765969 |
acc4420 |
AMPK |
phosphorylation |
Thr183 |
rat |
myocardial infarction |
H9c2 |
A-769662 |
decrease |
4.0 |
28765969 |
acc4421 |
mTOR |
phosphorylation |
Ser2448 |
rat |
myocardial infarction |
H9c2 |
A-769662 |
decrease |
4.0 |
28765969 |
acc4422 |
Akt |
phosphorylation |
Thr308 |
rat |
obese |
|
everolimus |
modulate |
4.0 |
28805979 |
acc4423 |
TRPV1 |
phosphorylation |
Ser502 |
rat |
colitis |
HEK293 |
Curcumin |
modulate |
4.0 |
28812431 |
acc4424 |
4EBP1 |
phosphorylation |
Thr70 |
human |
cancer |
HCT116 |
Ascochlorin |
modulate |
4.0 |
28833404 |
acc4425 |
ERK |
phosphorylation |
unclear |
human |
cancer |
HCT116 |
Ascochlorin |
modulate |
4.0 |
28833404 |
acc4426 |
p70S6K |
phosphorylation |
unclear |
human |
cancer |
HCT116 |
Ascochlorin |
modulate |
4.0 |
28833404 |
acc4427 |
YAP |
phosphorylation |
Ser127 |
rat |
ventricular cardiomyocytes |
|
Verteporfin() |
modulate |
4.0 |
28834610 |
acc4428 |
PHLPP2 |
phosphorylation |
Ser1119 |
mouse |
obese |
|
glucagon |
modulate |
4.0 |
28859855 |
acc4429 |
PHLPP2 |
phosphorylation |
Ser1210 |
mouse |
obese |
|
glucagon |
modulate |
4.0 |
28859855 |
acc4430 |
AMPKalpha |
phosphorylation |
Thr172 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4431 |
p38 MAPK |
phosphorylation |
Thr180 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4432 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4433 |
Smad2 |
phosphorylation |
Ser465 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4434 |
Smad2 |
phosphorylation |
Ser467 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4435 |
Smad3 |
phosphorylation |
Ser423 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4436 |
Smad3 |
phosphorylation |
Ser425 |
human |
diabetic |
HCF |
Curcumin |
modulate |
4.0 |
28905939 |
acc4437 |
eNOS |
phosphorylation |
Ser1177 |
rat |
peripheral artery disease |
|
Low molecular weight fucoidan (LMWF) |
modulate |
4.0 |
28917976 |
acc4438 |
ERK1 |
phosphorylation |
Thr202 |
rat |
cardiac fibrosis |
|
Eplerenone |
modulate |
4.0 |
28966243 |
acc4439 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
cardiac fibrosis |
|
Eplerenone |
modulate |
4.0 |
28966243 |
acc4440 |
ERK2 |
phosphorylation |
Thr185 |
rat |
cardiac fibrosis |
|
Eplerenone |
modulate |
4.0 |
28966243 |
acc4441 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
cardiac fibrosis |
|
Eplerenone |
modulate |
4.0 |
28966243 |
acc4442 |
Akt |
phosphorylation |
Thr308 |
mouse |
alcoholic fatty liver (AFL) |
HepG2£¨»¹ÓÐСÊóʵÑ飩 |
N-acetyl-L-cysteine (NAC) |
modulate |
4.0 |
28987868 |
acc4443 |
Akt |
phosphorylation |
Thr308 |
mouse |
alcoholic fatty liver (AFL) |
HepG2£¨»¹ÓÐСÊóʵÑ飩 |
insulin-like growth factor-1 (IGF-1) |
modulate |
4.0 |
28987868 |
acc4444 |
Drp1 |
phosphorylation |
Ser616 |
rat |
myocardial injury |
|
Melatonin |
modulate |
4.0 |
29024001 |
acc4445 |
CREB |
phosphorylation |
Ser133 |
mouse |
Alzheimer |
|
1w¡¤Cit |
modulate |
4.0 |
29068218 |
acc4446 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
hyperoxia-induced inflammation |
|
Fucoidan |
modulate |
4.0 |
29138816 |
acc4447 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
hyperoxia-induced inflammation |
|
Fucoidan |
modulate |
4.0 |
29138816 |
acc4448 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
hyperoxia-induced inflammation |
|
Fucoidan |
modulate |
4.0 |
29138816 |
acc4449 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
hyperoxia-induced inflammation |
|
Fucoidan |
modulate |
4.0 |
29138816 |
acc4450 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
Alpinetin |
modulate |
4.0 |
29156529 |
acc4451 |
IkappaBalpha |
phosphorylation |
Ser176 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
Alpinetin |
modulate |
4.0 |
29156529 |
acc4452 |
IkappaBalpha |
phosphorylation |
Ser180 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
Alpinetin |
modulate |
4.0 |
29156529 |
acc4453 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
Alpinetin |
modulate |
4.0 |
29156529 |
acc4454 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
Alpinetin |
modulate |
4.0 |
29156529 |
acc4455 |
Akt |
phosphorylation |
Ser473 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4456 |
cPLA2 |
phosphorylation |
Ser505 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4457 |
ERK1 |
phosphorylation |
Thr202 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4458 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4459 |
ERK2 |
phosphorylation |
Thr185 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4460 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4461 |
Lyn |
phosphorylation |
Tyr507 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4462 |
PLC-gamma1 |
phosphorylation |
Tyr783 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4463 |
Syk |
phosphorylation |
Tyr525 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4464 |
Syk |
phosphorylation |
Tyr526 |
rat |
allergic |
RBL-2H3 |
Davallia mariesii extract (DRE) |
modulate |
4.0 |
29200667 |
acc4465 |
PPARgamma |
phosphorylation |
Ser273 |
mouse |
diabetic |
3T3¨CL1 |
Dihydrosanguinarine |
modulate |
4.0 |
29202114 |
acc4466 |
Akt |
phosphorylation |
Ser473 |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4467 |
Akt |
phosphorylation |
Tyr |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4468 |
IRbeta |
phosphorylation |
Tyr1162 |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4469 |
IRbeta |
phosphorylation |
Tyr1163 |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4470 |
IRbeta |
phosphorylation |
Tyr |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4471 |
IRS1 |
phosphorylation |
Tyr632 |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4472 |
IRS1 |
phosphorylation |
Tyr |
mouse |
obese |
|
resveratrol |
modulate |
4.0 |
29229986 |
acc4473 |
JNK |
phosphorylation |
Thr183 |
human |
lung cancer |
A549 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4474 |
JNK |
phosphorylation |
Thr183 |
human |
colon cancer |
HCT116 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4475 |
JNK |
phosphorylation |
Tyr185 |
human |
lung cancer |
A549 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4476 |
JNK |
phosphorylation |
Tyr185 |
human |
colon cancer |
HCT116 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4477 |
JNK |
phosphorylation |
Thr183 |
human |
breast cancer |
MCF7 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4478 |
JNK |
phosphorylation |
Tyr185 |
human |
breast cancer |
MCF7 |
"8-Hydroxy-2-methoxy-1,4-naphthoquinone (HMNQ)" |
modulate |
4.0 |
29245930 |
acc4479 |
HSL |
phosphorylation |
Ser660 |
mouse |
myocardial infarction |
|
Gipr KO |
modulate |
3.0 |
29275960 |
acc4480 |
HSL |
phosphorylation |
Ser563 |
mouse |
myocardial infarction |
|
Gipr KO |
modulate |
3.0 |
29275960 |
acc4481 |
Akt |
phosphorylation |
Thr308 |
rat |
diabetic |
|
PTX |
modulate |
4.0 |
29357512 |
acc4482 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
PTX |
modulate |
4.0 |
29357512 |
acc4483 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Cardiac hypertrophy |
|
Anti-IL-22 (nAb) |
modulate |
4.0 |
29358851 |
acc4484 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Cardiac hypertrophy |
|
Anti-IL-22 (nAb) |
modulate |
4.0 |
29358851 |
acc4485 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Cardiac hypertrophy |
|
Anti-IL-22 (nAb) |
modulate |
4.0 |
29358851 |
acc4486 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Cardiac hypertrophy |
|
Anti-IL-22 (nAb) |
modulate |
4.0 |
29358851 |
acc4487 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
Cardiac hypertrophy |
|
Anti-IL-22 (nAb) |
modulate |
4.0 |
29358851 |
acc4488 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
cardiac fibrosis |
|
Rosmarinic acid |
modulate |
4.0 |
29367637 |
acc4489 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
cardiac fibrosis |
|
Rosmarinic acid |
modulate |
4.0 |
29367637 |
acc4490 |
Smad2 |
phosphorylation |
Ser465 |
rat |
unilateral ureteral obstruction |
/ |
dietary iron restriction |
modulate |
4.0 |
29417224 |
acc4491 |
Smad2 |
phosphorylation |
Ser467 |
rat |
unilateral ureteral obstruction |
/ |
dietary iron restriction |
modulate |
4.0 |
29417224 |
acc4492 |
HSP27 |
phosphorylation |
Ser85 |
rat |
cerebral ischemia |
|
KU¨C55933 |
modulate |
4.0 |
29510140 |
acc4493 |
Akt |
phosphorylation |
unclear |
rat |
"neurological deficit,brain infarct" |
|
DGMI |
modulate |
4.0 |
29542683 |
acc4494 |
CREB |
phosphorylation |
Ser133 |
rat |
"neurological deficit,brain infarct" |
|
DGMI |
modulate |
4.0 |
29542683 |
acc4495 |
AMPK |
phosphorylation |
Thr172 |
human |
Hepatic steatosis |
HepG2 |
PDX |
modulate |
4.0 |
29572342 |
acc4496 |
AMPK |
phosphorylation |
Thr183 |
human |
Hepatic steatosis |
HepG2 |
PDX |
modulate |
4.0 |
29572342 |
acc4497 |
AMPK |
phosphorylation |
Thr183 |
mouse |
Hepatic steatosis |
|
PDX |
modulate |
4.0 |
29572342 |
acc4498 |
AMPK |
phosphorylation |
Thr172 |
mouse |
Hepatic steatosis |
|
PDX |
modulate |
4.0 |
29572342 |
acc4499 |
eIF2alpha |
phosphorylation |
Ser51 |
human |
Hepatic steatosis |
HepG2 |
PDX |
modulate |
4.0 |
29572342 |
acc4500 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
Hepatic steatosis |
|
PDX |
modulate |
4.0 |
29572342 |
acc4501 |
IRE1 |
phosphorylation |
Ser274 |
human |
Hepatic steatosis |
HepG2 |
PDX |
modulate |
4.0 |
29572342 |
acc4502 |
IRE1 |
phosphorylation |
Ser274 |
mouse |
Hepatic steatosis |
|
PDX |
modulate |
4.0 |
29572342 |
acc4503 |
CREB |
phosphorylation |
Ser133 |
mouse |
Alzheimer |
|
3c¡¤cit |
modulate |
4.0 |
29616790 |
acc4504 |
JNK |
phosphorylation |
unclear |
mouse |
myocardial I/R injury |
|
Butorphanol |
modulate |
4.0 |
29630131 |
acc4505 |
P38 |
phosphorylation |
unclear |
mouse |
myocardial I/R injury |
|
Butorphanol |
modulate |
4.0 |
29630131 |
acc4506 |
CaMKII |
phosphorylation |
Met281 |
mouse |
Duchenne muscular dystrophy |
|
genetic inhibition |
inhibit |
4.5 |
29654126 |
acc4507 |
CaMKII |
phosphorylation |
Met282 |
mouse |
Duchenne muscular dystrophy |
|
genetic inhibition |
inhibit |
4.5 |
29654126 |
acc4508 |
TRAF6 |
ubiquitination |
Lys63 |
mouse |
Acute lung injury |
|
Tabersonine |
modulate |
4.0 |
29746822 |
acc4509 |
AKT |
phosphorylation |
unclear |
human |
pancreatic cancer |
|
Apatinib + APS |
modulate |
4.0 |
29785118 |
acc4510 |
ERK1 |
phosphorylation |
unclear |
human |
pancreatic cancer |
|
Apatinib + APS |
modulate |
4.0 |
29785118 |
acc4511 |
AMPK |
phosphorylation |
Thr183 |
mouse |
diabetic tubulopathy |
|
Chloroquine + amodiaquine |
modulate |
4.0 |
29884802 |
acc4512 |
AMPK |
phosphorylation |
Thr172 |
mouse |
diabetic tubulopathy |
|
Chloroquine + amodiaquine |
modulate |
4.0 |
29884802 |
acc4513 |
CaMKIIdelta |
phosphorylation |
Thr287 |
human |
type 2 diabetes mellitus |
|
KN93 |
modulate |
4.0 |
29903013 |
acc4514 |
CaMKIIdelta |
phosphorylation |
Thr287 |
rat |
type 2 diabetes mellitus |
|
AIP |
modulate |
4.0 |
29903013 |
acc4515 |
AMPK |
phosphorylation |
Thr183 |
rat |
cerebral ischemia |
|
Puerarin |
modulate |
4.0 |
29926825 |
acc4516 |
AMPK |
phosphorylation |
Thr172 |
rat |
cerebral ischemia |
|
Puerarin |
modulate |
4.0 |
29926825 |
acc4517 |
mTOR |
phosphorylation |
Ser2448 |
rat |
cerebral ischemia |
|
Puerarin |
modulate |
4.0 |
29926825 |
acc4518 |
ULK1 |
phosphorylation |
Ser317 |
rat |
cerebral ischemia |
|
Puerarin |
modulate |
4.0 |
29926825 |
acc4519 |
Smad3 |
phosphorylation |
Ser423 |
rat |
hepatic fibrosis |
hepatic stellate cells |
TF-SC |
modulate |
4.0 |
29990830 |
acc4520 |
RyR2 |
oxidation |
unclear |
pig |
arrhythmogenesis |
|
Flecainide |
modulate |
4.0 |
30028197 |
acc4521 |
FGFR1 |
phosphorylation |
Tyr654 |
human |
breast cancer |
|
tamoxifen |
inhibit |
5.0 |
30046001 |
acc4522 |
eNOS |
phosphorylation |
Ser1177 |
rat |
Endothelial senescence in hypertension |
|
Hemin |
modulate |
4.0 |
30048241 |
acc4523 |
ATM |
phosphorylation |
Ser1981 |
human |
glioblastoma multiforme(GBM) |
U87-MG |
Temozolomide (TMZ) + caffeine |
modulate |
4.0 |
30050935 |
acc4524 |
p53 |
phosphorylation |
unclear |
human |
glioblastoma multiforme(GBM) |
U87-MG |
Temozolomide (TMZ) + caffeine |
modulate |
4.0 |
30050935 |
acc4525 |
p38 |
Phosphorylation |
unclear |
rat |
myocardial infarction |
|
Atorvastatin |
modulate |
4.0 |
30116330 |
acc4526 |
NR2B |
phosphorylation |
Tyr1472 |
rat |
dyskinetic |
|
Tat-Src |
modulate |
4.0 |
30130562 |
acc4527 |
Src |
phosphorylation |
Tyr416 |
rat |
dyskinetic |
|
Tat-Src |
modulate |
4.0 |
30130562 |
acc4528 |
Src |
prenylation |
Cys |
rat |
dyskinetic |
|
Tat-Src |
modulate |
4.0 |
30130562 |
acc4529 |
Akt |
phosphorylation |
Ser473 |
mouse |
"Hepatic steatosis, insulin resistance" |
|
FO |
modulate |
4.0 |
30145885 |
acc4530 |
IRS1 |
phosphorylation |
Tyr632 |
mouse |
"Hepatic steatosis, insulin resistance" |
|
FO |
modulate |
4.0 |
30145885 |
acc4531 |
ERK |
phosphorylation |
unclear |
rat |
neuropathic pain |
|
dexmedetomidine |
modulate |
4.0 |
30181689 |
acc4532 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
peripheral arterial disease |
|
IL-22 antagonism |
modulate |
4.0 |
30236983 |
acc4533 |
ERK |
phosphorylation |
unclear |
mouse |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4534 |
ERK |
phosphorylation |
unclear |
rat |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4535 |
IkappaBalpha |
phosphorylation |
unclear |
mouse |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4536 |
IkappaBalpha |
phosphorylation |
unclear |
rat |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4537 |
JNK |
phosphorylation |
unclear |
mouse |
inflammatory |
|
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4538 |
JNK |
phosphorylation |
unclear |
rat |
inflammatory |
|
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4539 |
NF-kappaB p65 |
phosphorylation |
unclear |
mouse |
inflammatory |
|
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4540 |
NF-kappaB p65 |
phosphorylation |
unclear |
rat |
inflammatory |
|
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4541 |
p38 |
phosphorylation |
unclear |
mouse |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4542 |
p38 MAPK |
phosphorylation |
unclear |
rat |
inflammatory |
|
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4543 |
p65 |
phosphorylation |
unclear |
mouse |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4544 |
p65 |
phosphorylation |
unclear |
rat |
inflammatory |
RAW264.7 |
prethanol extract of Trifolium pratense |
modulate |
4.0 |
30320514 |
acc4545 |
AMPK |
phosphorylation |
Thr183 |
rat |
diabetic |
|
rimonabant |
modulate |
4.0 |
30365523 |
acc4546 |
AMPK |
phosphorylation |
Thr172 |
rat |
diabetic |
|
rimonabant |
modulate |
4.0 |
30365523 |
acc4547 |
histone H3 |
acetylation |
Lys9 |
rat |
depressive |
|
Venlafaxine (VEN) |
modulate |
3.0 |
30640193 |
acc4548 |
Akt |
phosphorylation |
Ser473 |
rat |
hypertension |
|
CoQ10 |
modulate |
4.0 |
30668894 |
acc4549 |
nNOS |
phosphorylation |
Ser1416 |
rat |
hypertension |
|
CoQ10 |
modulate |
4.0 |
30668894 |
acc4550 |
p38 MAP kinase |
phosphorylation |
Thr180/Tyr182 |
rat |
hypertension |
|
CoQ10 |
modulate |
4.0 |
30668894 |
acc4551 |
JNK |
phosphorylation |
Thr183 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
VB-037 |
modulate |
4.0 |
30707915 |
acc4552 |
JNK |
phosphorylation |
Tyr185 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
VB-037 |
modulate |
4.0 |
30707915 |
acc4553 |
JUN |
phosphorylation |
Ser63 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
VB-037 |
modulate |
4.0 |
30707915 |
acc4554 |
p38 |
phosphorylation |
Thr180 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
VB-037 |
modulate |
4.0 |
30707915 |
acc4555 |
p38 |
phosphorylation |
Tyr182 |
human |
Alzheimer's disease (AD) |
SH-SY5Y |
VB-037 |
modulate |
4.0 |
30707915 |
acc4556 |
ERK |
phosphorylation |
unclear |
human |
atopic dermatitis(AD) |
HMC-1 |
JC3 |
modulate |
4.0 |
30729380 |
acc4557 |
JNK |
phosphorylation |
unclear |
human |
atopic dermatitis(AD) |
HMC-1 |
JC3 |
modulate |
4.0 |
30729380 |
acc4558 |
p38 |
phosphorylation |
unclear |
human |
atopic dermatitis(AD) |
HMC-1 |
JC3 |
modulate |
4.0 |
30729380 |
acc4559 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4560 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4561 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4562 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4563 |
JNK |
phosphorylation |
Thr183 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4564 |
JNK |
phosphorylation |
Tyr185 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4565 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
diabetic nephropathy |
|
AM095 |
modulate |
4.0 |
30763641 |
acc4566 |
PLN |
phosphorylation |
Ser16 |
rat |
cardiac hypertrophy |
H9c2 |
lithocholic acid (LCA) |
modulate |
4.0 |
30842472 |
acc4567 |
AMPK |
phosphorylation |
Thr183 |
rat |
Central nervous system (CNS) inflammation |
PC12 |
salidroside |
modulate |
4.0 |
30848530 |
acc4568 |
AMPK |
phosphorylation |
Thr172 |
rat |
Central nervous system (CNS) inflammation |
PC12 |
salidroside |
modulate |
4.0 |
30848530 |
acc4569 |
IkappaBalpha |
phosphorylation |
Ser32 |
rat |
Central nervous system (CNS) inflammation |
PC12 |
salidroside |
modulate |
4.0 |
30848530 |
acc4570 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
rat |
Central nervous system (CNS) inflammation |
PC12 |
salidroside |
modulate |
4.0 |
30848530 |
acc4571 |
JNK |
phosphorylation |
unclear |
mouse |
mitochondrial dysfunction |
|
farrerol |
modulate |
4.0 |
30906210 |
acc4572 |
alpha-tubulin |
acetylation |
Lys40 |
mouse |
Bacterial infection |
J774A.1 |
Evodiamine |
modulate |
4.0 |
30971927 |
acc4573 |
AMPK |
phosphorylation |
Thr183 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4574 |
AMPK |
phosphorylation |
Thr172 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4575 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4576 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4577 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4578 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4579 |
JNK |
phosphorylation |
Thr183 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4580 |
JNK |
phosphorylation |
Tyr185 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4581 |
P38 |
phosphorylation |
Thr180 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4582 |
P38 |
phosphorylation |
Tyr182 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4583 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
Acute liver injury |
|
Thymoquinone (TQ) |
modulate |
4.0 |
30974967 |
acc4584 |
Akt |
phosphorylation |
Ser473 |
mouse |
myocardial hypertrophy |
|
Tempol |
modulate |
4.0 |
31047988 |
acc4585 |
p65 |
phosphorylation |
Ser536 |
mouse |
neuronal damage |
BV-2 |
FTY720 |
modulate |
4.0 |
31069623 |
acc4586 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
Acute liver injury |
|
CAY10594 |
modulate |
4.0 |
31076618 |
acc4587 |
JNK |
phosphorylation |
unclear |
mouse |
Acute liver injury |
|
CAY10594 |
modulate |
4.0 |
31076618 |
acc4588 |
CRMP2 |
phosphorylation |
Ser522 |
mouse |
Axonal degeneration |
|
CRMP2 KI |
modulate |
3.0 |
31076621 |
acc4589 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
Type 1 diabetes mellitus (T1DM) |
|
Metformin |
modulate |
4.0 |
31105845 |
acc4590 |
Chk1 |
phosphorylation |
Ser345 |
human |
excessive mitotic abnormalities |
AG11395 |
camptothecin |
modulate |
4.0 |
31114910 |
acc4591 |
MUS81 |
phosphorylation |
Ser87 |
human |
excessive mitotic abnormalities |
AG11395 |
camptothecin |
modulate |
4.0 |
31114910 |
acc4592 |
P38 |
phosphorylation |
unclear |
mouse |
neuronal loss |
|
LPS |
modulate |
4.0 |
31124385 |
acc4593 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
cleft palate |
|
folic acid (FA) |
modulate |
4.0 |
31171577 |
acc4594 |
NOS3 |
phosphorylation |
Ser1177 |
human |
colorectal cancer (CRC) |
DLD-1 |
Oxaliplatin |
resist |
5.0 |
31195721 |
acc4595 |
NOS3 |
phosphorylation |
Ser1177 |
human |
colorectal cancer (CRC) |
Colo205 |
Oxaliplatin |
resist |
5.0 |
31195721 |
acc4596 |
HDAC4 |
O-GlcNAcylation |
Ser642 |
mouse |
heart failure |
|
HDAC4-KO |
modulate |
3.0 |
31195810 |
acc4597 |
HDAC4 |
phosphorylation |
Ser632 |
mouse |
heart failure |
|
HDAC4-KO |
modulate |
3.0 |
31195810 |
acc4598 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
gestational diabetes mellitus |
H9C2 |
high glucose |
modulate |
4.0 |
31197456 |
acc4599 |
Akt2 |
phosphorylation |
Ser474 |
mouse |
obese |
L02 |
Pituitary adenylate cyclase-activating polypeptide (PACAP) |
modulate |
4.0 |
31270932 |
acc4600 |
CREB |
phosphorylation |
Ser133 |
mouse |
cognitive impairment |
|
levetiracetam |
modulate |
4.0 |
31302262 |
acc4601 |
Rb |
phosphorylation |
unclear |
mouse |
diabetic cardiomyopathy |
|
Palbociclib |
modulate |
4.0 |
31312360 |
acc4602 |
EGFR |
phosphorylation |
Tyr845 |
human |
respiratory syncytial virus (RSV) |
A549 |
PST2238 |
modulate |
4.0 |
31381610 |
acc4603 |
EGFR |
phosphorylation |
Tyr845 |
human |
respiratory syncytial virus (RSV) |
HSAEC |
PST2238 |
modulate |
4.0 |
31381610 |
acc4604 |
p53 |
phosphorylation |
unclear |
human |
"endothelial cell injury, apoptosis" |
HUVEC |
ACTN4 OE |
modulate |
3.0 |
31399951 |
acc4605 |
Smad3 |
phosphorylation |
Ser204 |
mouse |
asthma |
|
Atrial natriuretic peptide (ANP) |
modulate |
4.0 |
31496319 |
acc4606 |
cystathionine beta-synthase |
nitration |
unclear |
mouse |
Acute pancreatitis |
|
S-adenosylmethionine |
modulate |
4.0 |
31539805 |
acc4607 |
JNK |
phosphorylation |
Thr183 |
rat |
Diabetic nephropathy |
|
All-Trans Retinoic Acid |
modulate |
4.0 |
31557800 |
acc4608 |
JNK |
phosphorylation |
Tyr185 |
rat |
Diabetic nephropathy |
|
All-Trans Retinoic Acid |
modulate |
4.0 |
31557800 |
acc4609 |
Smad3 |
phosphorylation |
Ser423 |
rat |
Diabetic nephropathy |
|
All-Trans Retinoic Acid |
modulate |
4.0 |
31557800 |
acc4610 |
Smad3 |
phosphorylation |
Ser425 |
rat |
Diabetic nephropathy |
|
All-Trans Retinoic Acid |
modulate |
4.0 |
31557800 |
acc4611 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetes mellitus |
|
CAF6 |
modulate |
4.0 |
31566891 |
acc4612 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetes mellitus |
|
CAF12 |
modulate |
4.0 |
31566891 |
acc4613 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetes mellitus |
|
CAF6 |
modulate |
4.0 |
31566891 |
acc4614 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetes mellitus |
|
CAF6 |
modulate |
4.0 |
31566891 |
acc4615 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetes mellitus |
|
CAF12 |
modulate |
4.0 |
31566891 |
acc4616 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetes mellitus |
|
CAF12 |
modulate |
4.0 |
31566891 |
acc4617 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetes mellitus |
|
CAF6 |
modulate |
4.0 |
31566891 |
acc4618 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetes mellitus |
|
CAF6 |
modulate |
4.0 |
31566891 |
acc4619 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetes mellitus |
|
CAF12 |
modulate |
4.0 |
31566891 |
acc4620 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetes mellitus |
|
CAF12 |
modulate |
4.0 |
31566891 |
acc4621 |
ACC |
phosphorylation |
Ser79 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4622 |
AMPK |
phosphorylation |
Thr172 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4623 |
AMPK |
phosphorylation |
Thr183 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4624 |
mTOR |
phosphorylation |
Ser2448 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4625 |
p70S6K |
phosphorylation |
Thr389 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4626 |
SREBP1c |
phosphorylation |
Ser372 |
human |
Hepatic steatosis |
HepG2 |
PCW |
modulate |
4.0 |
31569635 |
acc4627 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
diabetic |
|
Betaine |
modulate |
4.0 |
31585299 |
acc4628 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
diabetic |
|
Betaine |
modulate |
4.0 |
31585299 |
acc4629 |
FAK |
phosphorylation |
Tyr397 |
human |
mucosal ulcer |
Caco-2 |
ZINC40099027 |
modulate |
4.0 |
31604999 |
acc4630 |
FAK |
phosphorylation |
Tyr397 |
mouse |
mucosal ulcer |
|
ZINC40099027 |
modulate |
4.0 |
31604999 |
acc4631 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Pregnancy-associated cardiomyopathy |
|
LCZ696 |
modulate |
4.0 |
31649814 |
acc4632 |
MARCKS |
phosphorylation |
Ser158 |
human |
IPF |
|
MPS peptide |
modulate |
3.0 |
31661644 |
acc4633 |
GSK3alpha |
phosphorylation |
Ser21 |
mouse |
myopathic conditions |
C2C12 |
Lithium |
modulate |
4.0 |
31671858 |
acc4634 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
myopathic conditions |
C2C12 |
Lithium |
modulate |
4.0 |
31671858 |
acc4635 |
FOXO3a |
phosphorylation |
Ser253 |
human |
Polycystic ovary syndrome (PCOS) |
|
berberine |
promote |
4.0 |
31706105 |
acc4636 |
SIRT3 |
ubiquitination |
unclear |
human |
Polycystic ovary syndrome (PCOS) |
|
berberine |
promote |
4.0 |
31706105 |
acc4637 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
diabetic |
|
RAPA |
modulate |
4.0 |
31738412 |
acc4638 |
ERK |
phosphorylation |
Tyr204 |
rat |
neuropathic pain |
|
PD98059 |
inhibit |
5.0 |
31765435 |
acc4639 |
Akt |
phosphorylation |
Ser473 |
rat |
cardiac damage |
H9c2 |
Metformin+N-Acetyl Cysteine |
modulate |
4.0 |
31766382 |
acc4640 |
AMPK |
phosphorylation |
Thr183 |
rat |
cardiac damage |
H9c2 |
Metformin+N-Acetyl Cysteine |
modulate |
4.0 |
31766382 |
acc4641 |
AMPK |
phosphorylation |
Thr172 |
rat |
cardiac damage |
H9c2 |
Metformin+N-Acetyl Cysteine |
modulate |
4.0 |
31766382 |
acc4642 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
obese |
|
Quercetin |
modulate |
4.0 |
31781748 |
acc4643 |
Akt |
phosphorylation |
unclear |
rat |
myocardial ischemia-reperfusion injury |
|
fibrauretine |
modulate |
3.0 |
31796985 |
acc4644 |
ERK1 |
phosphorylation |
Thr202 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4645 |
ERK1 |
phosphorylation |
Tyr204 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4646 |
ERK2 |
phosphorylation |
Thr185 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4647 |
ERK2 |
phosphorylation |
Tyr187 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4648 |
JNK1 |
phosphorylation |
Thr183 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4649 |
JNK1 |
phosphorylation |
Tyr185 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4650 |
JNK2 |
phosphorylation |
Thr183 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4651 |
JNK2 |
phosphorylation |
Tyr185 |
human |
Atopic dermatitis |
HaCaT |
"7,3',4'-trihydroxyisoflavone" |
modulate |
4.0 |
31853913 |
acc4652 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
"mitochondrial dysfunction,neuronal loss" |
SN4741 |
mutant A53T alpha-synuclein |
modulate |
3.0 |
31881179 |
acc4653 |
GR |
phosphorylation |
Ser246 |
rat |
depressive |
|
SP600125 |
modulate |
4.0 |
31901732 |
acc4654 |
JNK |
phosphorylation |
Thr183 |
rat |
depressive |
|
SP600125 |
modulate |
4.0 |
31901732 |
acc4655 |
JNK |
phosphorylation |
Tyr185 |
rat |
depressive |
|
SP600125 |
modulate |
4.0 |
31901732 |
acc4656 |
AMPK |
phosphorylation |
Thr183 |
mouse |
colitis |
|
Metrnl KO |
modulate |
3.0 |
31949292 |
acc4657 |
AMPK |
phosphorylation |
Thr172 |
mouse |
colitis |
|
Metrnl KO |
modulate |
3.0 |
31949292 |
acc4658 |
mTOR |
phosphorylation |
Ser2448 |
mouse |
colitis |
|
Metrnl KO |
modulate |
3.0 |
31949292 |
acc4659 |
p70S6K |
phosphorylation |
Ser371 |
mouse |
colitis |
|
Metrnl KO |
modulate |
3.0 |
31949292 |
acc4660 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
prion diseases |
RML-ScCAD5 |
Sephin1 |
modulate |
4.0 |
31981074 |
acc4661 |
eIF2alpha |
phosphorylation |
Ser51 |
mouse |
prion diseases |
N2a |
Sephin1 |
modulate |
4.0 |
31981074 |
acc4662 |
JAK2 |
phosphorylation |
Tyr1007 |
human |
Breast cancer |
MCF-7 |
Brc-A |
modulate |
4.0 |
32021288 |
acc4663 |
JAK2 |
phosphorylation |
Tyr1008 |
human |
Breast cancer |
MCF-7 |
Brc-A |
modulate |
4.0 |
32021288 |
acc4664 |
SRC |
phosphorylation |
unclear |
human |
Breast cancer |
MCF-7 |
Brc-A |
modulate |
4.0 |
32021288 |
acc4665 |
S6 |
phosphorylation |
Ser235 |
human |
melanoma |
A375 |
TM |
modulate |
4.0 |
32085796 |
acc4666 |
S6 |
phosphorylation |
Ser235 |
human |
melanoma |
RPMI |
TM |
modulate |
4.0 |
32085796 |
acc4667 |
S6 |
phosphorylation |
Ser235 |
human |
melanoma |
SH4 |
TM |
modulate |
4.0 |
32085796 |
acc4668 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
Acute lung injury (ALI) |
|
HSPH1 inhibitor(KNK437) |
modulate |
4.0 |
32091104 |
acc4669 |
Akt |
phosphorylation |
Thr308 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4670 |
CREB |
phosphorylation |
Ser133 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4671 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4672 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4673 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4674 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4675 |
PI3K |
phosphorylation |
Tyr199 |
mouse |
Alzheimer |
|
maslinic acid |
modulate |
4.0 |
32133639 |
acc4676 |
PARP1 |
ubiquitination |
Lys249 |
mouse |
heart failure |
|
WWP2 knockout |
modulate |
3.0 |
32139900 |
acc4677 |
PARP1 |
ubiquitination |
Lys418 |
mouse |
heart failure |
|
WWP2 knockout |
modulate |
3.0 |
32139900 |
acc4678 |
JAK2 |
phosphorylation |
Tyr1007 |
rabbit |
atherosclerosis |
|
Ruxolitinib |
modulate |
4.0 |
32169038 |
acc4679 |
JAK2 |
phosphorylation |
Tyr1008 |
rabbit |
atherosclerosis |
|
Ruxolitinib |
modulate |
4.0 |
32169038 |
acc4680 |
STAT3 |
phosphorylation |
Tyr705 |
rabbit |
atherosclerosis |
|
Ruxolitinib |
modulate |
4.0 |
32169038 |
acc4681 |
Akt |
phosphorylation |
Ser473 |
mouse |
high-fat diet (HFD) |
MC-IXC |
chloroform fraction from Actinidia arguta |
modulate |
4.0 |
32238886 |
acc4682 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
high-fat diet (HFD) |
MC-IXC |
chloroform fraction from Actinidia arguta |
modulate |
4.0 |
32238886 |
acc4683 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
high-fat diet (HFD) |
MC-IXC |
chloroform fraction from Actinidia arguta |
modulate |
4.0 |
32238886 |
acc4684 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
high-fat diet (HFD) |
MC-IXC |
chloroform fraction from Actinidia arguta |
modulate |
4.0 |
32238886 |
acc4685 |
Smad3 |
phosphorylation |
Ser423 |
rat |
diabetic |
|
HC067047 |
modulate |
4.0 |
32274619 |
acc4686 |
Smad3 |
phosphorylation |
Ser425 |
rat |
diabetic |
|
HC067047 |
modulate |
4.0 |
32274619 |
acc4687 |
eNOS |
phosphorylation |
ser1177 |
mouse |
atherosclerosis |
|
dihydromyricetin (DMY) |
modulate |
4.0 |
32301289 |
acc4688 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
cardiac injury |
NMVM |
doxorubicin |
inhibit |
5.0 |
32339784 |
acc4689 |
SNAP-25 |
phosphorylation |
Ser187 |
mouse |
epilepsy |
|
BRV |
modulate |
4.0 |
32407277 |
acc4690 |
JNK |
phosphorylation |
Thr183 |
mouse |
diabetic |
|
melatonin |
modulate |
4.0 |
32411318 |
acc4691 |
JNK |
phosphorylation |
Tyr185 |
mouse |
diabetic |
|
melatonin |
modulate |
4.0 |
32411318 |
acc4692 |
Titin |
phosphorylation |
Ser4010 |
human |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4693 |
Titin |
phosphorylation |
Ser4099 |
human |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4694 |
Titin |
phosphorylation |
Ser3991 |
rat |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4695 |
Titin |
phosphorylation |
Ser4043 |
rat |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4696 |
Titin |
phosphorylation |
Ser4080 |
rat |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4697 |
Titin |
phosphorylation |
Ser12742 |
rat |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4698 |
Titin |
phosphorylation |
Ser12884 |
rat |
Heart Failure with Preserved Ejection Fraction |
|
sGC stimulator |
modulate |
4.0 |
32523538 |
acc4699 |
STAT5 |
phosphorylation |
unclear |
mouse |
myeloproliferative disease |
|
fedratinib |
modulate |
4.0 |
32647323 |
acc4700 |
eNOS |
phosphorylation |
Tyr81 |
human |
diabetic endothelial dysfunction |
|
AKB-9778 |
modulate |
4.0 |
32653904 |
acc4701 |
eNOS |
phosphorylation |
Ser1177 |
human |
diabetic endothelial dysfunction |
|
AKB-9778 |
modulate |
4.0 |
32653904 |
acc4702 |
eNOS |
phosphorylation |
Tyr80 |
mouse |
diabetic endothelial dysfunction |
|
AKB-9778 |
modulate |
4.0 |
32653904 |
acc4703 |
eNOS |
phosphorylation |
Ser1176 |
mouse |
diabetic endothelial dysfunction |
|
AKB-9778 |
modulate |
4.0 |
32653904 |
acc4704 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
Endothelial dysfunction |
|
metoprolol |
modulate |
4.0 |
32704438 |
acc4705 |
JAK2 |
phosphorylation |
unclear |
mouse |
colitis |
|
TAK-242 |
modulate |
4.0 |
32762699 |
acc4706 |
STAT3 |
phosphorylation |
unclear |
mouse |
colitis |
|
TAK-242 |
modulate |
4.0 |
32762699 |
acc4707 |
PRDX3 |
acetylation |
unclear |
human |
beta-cell dysfunction |
human beta cells (1.1B4) |
high glucose |
modulate |
4.0 |
32763411 |
acc4708 |
PRDX3 |
acetylation |
unclear |
rat |
beta-cell dysfunction |
rat insulinoma INS-1cells |
high glucose |
modulate |
4.0 |
32763411 |
acc4709 |
Bcl-2 |
phosphorylation |
Ser70 |
human |
NSCLC |
NCI-H460 |
"vinorelbine,YL-9" |
modulate |
4.0 |
32764382 |
acc4710 |
Smad2 |
phosphorylation |
unclear |
human |
pulmonary fibrosis |
NHLF¡¢DHLF¡¢LL29 |
Biochanin-A(BCA) |
inhibit |
4.0 |
32781391 |
acc4711 |
Smad3 |
phosphorylation |
unclear |
human |
pulmonary fibrosis |
NHLF¡¢DHLF¡¢LL29 |
Biochanin-A(BCA) |
inhibit |
4.0 |
32781391 |
acc4712 |
TGF-beta |
phosphorylation |
unclear |
human |
pulmonary fibrosis |
NHLF¡¢DHLF¡¢LL29 |
Biochanin-A(BCA) |
inhibit |
4.0 |
32781391 |
acc4713 |
Connexin43 |
phosphorylation |
Ser368 |
rat |
Acute myocardial ischaemia and reperfusion (I-R) |
|
Ursodeoxycholic acid (UDCA) |
modulate |
4.0 |
32943714 |
acc4714 |
PPAR-gamma |
phosphorylation |
Ser112 |
rat |
anxiety |
|
AE-PG |
modulate |
4.0 |
33049337 |
acc4715 |
PP2A |
phosphorylation |
unclear |
human |
endothelial dysfunction |
HUVECs |
Angiotensin II |
modulate |
4.0 |
33162896 |
acc4716 |
PP2A |
phosphorylation |
unclear |
mouse |
endothelial dysfunction |
Sprague¨CDawley rat |
Angiotensin II |
modulate |
4.0 |
33162896 |
acc4717 |
Rac1 |
nitration |
Tyr32 |
mouse |
Acute lung injury (ALI) |
|
NipR2 (nitration inhibitor peptide for the Rho GTPases 2) |
modulate |
4.0 |
33248422 |
acc4718 |
Akt |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4719 |
ERK |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4720 |
IRS1 |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4721 |
JNK |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4722 |
MAPK |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4723 |
p38 MAPK |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4724 |
PI3K |
phosphorylation |
unclear |
mouse |
"obesity, steatosis" |
|
CTFV |
modulate |
4.0 |
33273564 |
acc4725 |
GluR1 |
phosphorylation |
unclear |
mouse |
Alzheimer's disease (AD) |
|
photobiomodulation (PBM) |
modulate |
3.0 |
33336891 |
acc4726 |
JNK3 |
phosphorylation |
unclear |
mouse |
Alzheimer's disease (AD) |
|
photobiomodulation (PBM) |
modulate |
3.0 |
33336891 |
acc4727 |
ERK1 |
phosphorylation |
Thr202 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4728 |
ERK1 |
phosphorylation |
Tyr204 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4729 |
ERK2 |
phosphorylation |
Thr185 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4730 |
ERK2 |
phosphorylation |
Tyr187 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4731 |
JNK |
phosphorylation |
Thr183 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4732 |
JNK |
phosphorylation |
Tyr185 |
human |
cervical cancer |
HeLa |
SP-FA |
modulate |
4.0 |
33357846 |
acc4733 |
ERK |
phosphorylation |
Thr202 |
rat |
colonic hypersensitivity |
|
linaclotide |
modulate |
4.0 |
33373484 |
acc4734 |
ERK |
phosphorylation |
Tyr204 |
rat |
colonic hypersensitivity |
|
linaclotide |
modulate |
4.0 |
33373484 |
acc4735 |
ERK |
phosphorylation |
Thr185 |
rat |
colonic hypersensitivity |
|
linaclotide |
modulate |
4.0 |
33373484 |
acc4736 |
ERK |
phosphorylation |
Tyr187 |
rat |
colonic hypersensitivity |
|
linaclotide |
modulate |
4.0 |
33373484 |
acc4737 |
AKT |
phosphorylation |
Ser473 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4738 |
ERK1 |
phosphorylation |
Thr202 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4739 |
ERK1 |
phosphorylation |
Tyr204 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4740 |
ERK2 |
phosphorylation |
Thr185 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4741 |
ERK2 |
phosphorylation |
Tyr187 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4742 |
S6 |
phosphorylation |
Ser240 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4743 |
S6 |
phosphorylation |
Ser244 |
human |
pancreatic cancer |
MIAPaCa-2 |
CUDC-907 |
inhibit |
5.0 |
33392641 |
acc4744 |
PGC1alpha |
acetylation |
Lys |
rat |
cardiac and neurological injuries |
H9c2 |
ginsenoside Rc |
modulate |
4.0 |
33439015 |
acc4745 |
PGC1alpha |
acetylation |
Lys |
rat |
cardiac and neurological injuries |
PC12 |
ginsenoside Rc |
modulate |
4.0 |
33439015 |
acc4746 |
IkappaBalpha |
phosphorylation |
Ser32 |
mouse |
colitis |
|
coptisine(COP) |
modulate |
4.0 |
33508280 |
acc4747 |
IkappaBalpha |
phosphorylation |
Ser36 |
mouse |
colitis |
|
coptisine(COP) |
modulate |
4.0 |
33508280 |
acc4748 |
HSP27 |
phosphorylation |
Ser85 |
rat |
cerebral ischemia |
Wistar rat |
Geranylgeranylacetone |
modulate |
4.0 |
33557752 |
acc4749 |
HMGB1 |
acetylation |
Lys12 |
rat |
Hyperoxic lung injury |
|
KYC |
modulate |
4.0 |
33607217 |
acc4750 |
MPO |
oxidation |
unclear |
rat |
Hyperoxic lung injury |
|
KYC |
modulate |
4.0 |
33607217 |
acc4751 |
Keap1 |
S-glutathionylation |
unclear |
rat |
Hyperoxic lung injury |
|
KYC |
modulate |
4.0 |
33607217 |
acc4752 |
HMGB1 |
thiylation |
unclear |
rat |
Hyperoxic lung injury |
|
KYC |
modulate |
4.0 |
33607217 |
acc4753 |
Keap1 |
thiylation |
unclear |
rat |
Hyperoxic lung injury |
|
KYC |
modulate |
4.0 |
33607217 |
acc4754 |
EGFR |
phosphorylation |
Tyr1173 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4755 |
EGFR |
phosphorylation |
Tyr1173 |
rat |
renal fibrosis |
NRK-44F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4756 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4757 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
rat |
renal fibrosis |
NRK-49F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4758 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4759 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4760 |
Smad3 |
phosphorylation |
Ser423 |
rat |
renal fibrosis |
NRK-46F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4761 |
Smad3 |
phosphorylation |
Ser425 |
rat |
renal fibrosis |
NRK-47F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4762 |
Src |
phosphorylation |
Tyr416 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4763 |
Src |
phosphorylation |
Tyr416 |
rat |
renal fibrosis |
NRK-45F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4764 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
renal fibrosis |
|
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4765 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
renal fibrosis |
NRK-48F |
Nintedanib + Gefitinib |
modulate |
4.0 |
33614732 |
acc4766 |
STAT3 |
acetylation |
Lys685 |
rat |
Ocular hypertension |
|
SNC-121 |
modulate |
4.0 |
33628191 |
acc4767 |
STAT3 |
acetylation |
Lys686 |
rat |
glaucomatous injury |
|
SNC-121 |
modulate |
4.0 |
33628191 |
acc4768 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
Ocular hypertension |
|
SNC-121 |
modulate |
4.0 |
33628191 |
acc4769 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
glaucomatous injury |
|
SNC-121 |
modulate |
4.0 |
33628191 |
acc4770 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
colitis |
|
15d-PGJ2 |
modulate |
4.0 |
33633749 |
acc4771 |
Smad3 |
acetylation |
Lys |
mouse |
cardiac fibrosis |
|
isoproterenol |
modulate |
4.0 |
33675899 |
acc4772 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
colitis |
|
Nr3c1 KO |
modulate |
3.0 |
33684964 |
acc4773 |
AKT |
phosphorylation |
Ser473 |
human |
Hepatocellular carcinoma |
SMMC-7721 ºÍ Bel-7402 ÒìÖÖÒÆÖ²Ö×Áö |
PI3Kalpha inhibitor + AL3810 (µ«µ¼ÖÂÁ×ËữµÄÖ»ÓÐAL3810) |
modulate |
4.0 |
33785733 |
acc4774 |
Akt |
phosphorylation |
Ser473 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
OBB |
modulate |
4.0 |
33831691 |
acc4775 |
Akt |
phosphorylation |
Thr308 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
OBB |
modulate |
4.0 |
33831691 |
acc4776 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
OBB |
modulate |
4.0 |
33831691 |
acc4777 |
IRS1 |
phosphorylation |
Ser1101 |
mouse |
non-alcoholic fatty liver disease (NAFLD) |
|
OBB |
modulate |
4.0 |
33831691 |
acc4778 |
Creb1 |
phosphorylation |
Ser133 |
mouse |
hypoglycemia |
|
glucose |
modulate |
4.0 |
33883213 |
acc4779 |
Akt |
phosphorylation |
Ser473 |
rat |
cognitive dysfunction |
|
IGF-1 |
modulate |
4.0 |
33949883 |
acc4780 |
Smad3 |
phosphorylation |
Ser204 |
mouse |
diabetic |
|
dapagliflozin |
modulate |
4.0 |
34003249 |
acc4781 |
ERK1 |
phosphorylation |
Thr202 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4782 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4783 |
ERK2 |
phosphorylation |
Thr185 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4784 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4785 |
P38 |
phosphorylation |
Thr180 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4786 |
P38 |
phosphorylation |
Tyr182 |
rat |
Subarachnoid hemorrhage (SAH) |
|
Hydrogen gas |
modulate |
4.0 |
34149882 |
acc4787 |
Akt |
phosphorylation |
Ser473 |
mouse |
obese |
|
short-term strength exercise (STSE) |
modulate |
3.0 |
34203825 |
acc4788 |
IRS1 |
phosphorylation |
Tyr612 |
mouse |
obese |
|
short-term strength exercise (STSE) |
modulate |
3.0 |
34203825 |
acc4789 |
Akt |
phosphorylation |
Ser473 |
mouse |
Plasmalogen deficiency |
|
TDG |
modulate |
4.0 |
34302896 |
acc4790 |
Akt |
phosphorylation |
Thr308 |
mouse |
Plasmalogen deficiency |
|
TDG |
modulate |
4.0 |
34302896 |
acc4791 |
VGLL4 |
acetylation |
unclear |
mouse |
Pulmonary hypertension |
PASMCs |
resveratrol |
modulate |
4.0 |
34314061 |
acc4792 |
p65 |
phosphorylation |
Ser536 |
mouse |
atopic dermatitis (AD) |
|
gomisin M2 (GM2) |
modulate |
4.0 |
34361560 |
acc4793 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
atopic dermatitis (AD) |
|
gomisin M2 (GM2) |
modulate |
4.0 |
34361560 |
acc4794 |
ERK1 |
phosphorylation |
Thr202 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4795 |
ERK1 |
phosphorylation |
Tyr204 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4796 |
ERK2 |
phosphorylation |
Thr185 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4797 |
ERK2 |
phosphorylation |
Tyr187 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4798 |
IkappaB |
phosphorylation |
unclear |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4799 |
JNK |
phosphorylation |
Thr183 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4800 |
JNK |
phosphorylation |
Tyr185 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4801 |
NF-kappaB p65 |
phosphorylation |
unclear |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4802 |
p38 MAPK |
phosphorylation |
Thr180 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4803 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
atopic dermatitis |
HaCaT |
Rosa davurica Pall. |
modulate |
4.0 |
34455178 |
acc4804 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4805 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4806 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4807 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4808 |
P38 |
phosphorylation |
Thr180 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4809 |
P38 |
phosphorylation |
Tyr182 |
mouse |
Acute lung injury (ALI) |
|
Chalcone derivatives 7w and(or) 7x |
modulate |
4.0 |
34480112 |
acc4810 |
IL-33 |
acetylation |
unclear |
mouse |
asthma |
|
MG149 |
modulate |
4.0 |
34493712 |
acc4811 |
IL-33 |
acetylation |
unclear |
mouse |
asthma |
|
MG149 |
modulate |
4.0 |
34493712 |
acc4812 |
NF-kappaB p65 |
phosphorylation |
Ser468 |
mouse |
intestinal barrier injury |
|
Morchella importunaFlavones |
modulate |
4.0 |
34552579 |
acc4813 |
Nrf2 |
phosphorylation |
Ser40 |
mouse |
intestinal barrier injury |
|
Morchella importunaFlavones |
modulate |
4.0 |
34552579 |
acc4814 |
ACC |
phosphorylation |
Ser79 |
mouse |
metabolic syndrome |
|
18:0 Lyso PC |
modulate |
4.0 |
34607170 |
acc4815 |
AMPKalpha |
phosphorylation |
Thr172 |
mouse |
metabolic syndrome |
|
18:0 Lyso PC |
modulate |
4.0 |
34607170 |
acc4816 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
Novel Triterpenoids fromCassia fistula |
modulate |
4.0 |
34833905 |
acc4817 |
IRS1 |
phosphorylation |
Tyr612 |
rat |
diabetic |
|
Novel Triterpenoids fromCassia fistula |
modulate |
4.0 |
34833905 |
acc4818 |
CypD |
acetylation |
unclear |
human |
Damage in Chondrocytes (mitochondrial dysfunction ) |
|
Rg3 |
modulate |
4.0 |
34943075 |
acc4819 |
Drp1 |
phosphorylation |
Tyr628 |
mouse |
aortic valve calcificatio |
VICs |
Tetrahydrobiopterin (BH4) |
modulate |
4.0 |
35139535 |
acc4820 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
cardiomyopathy |
|
Sunitinib |
modulate |
4.0 |
35157045 |
acc4821 |
IkappaBalpha |
phosphorylation |
Ser32 |
rat |
allergic |
|
"3,4-dihydroxybenzaldehyde (DHB)" |
modulate |
4.0 |
35200662 |
acc4822 |
ULK1 |
ubiquitination |
unclear |
mouse |
cardiac infarction |
|
TRAF3 OE |
modulate |
3.0 |
35318880 |
acc4823 |
CREB |
phosphorylation |
Ser133 |
mouse |
depressive |
|
naringin |
modulate |
4.0 |
35478969 |
acc4824 |
PPAR-gamma |
phosphorylation |
Ser112 |
mouse |
acute lung injury (ALI) |
|
Forsythiae Fructuse (FF) |
modulate |
4.0 |
35483561 |
acc4825 |
RXR-alpha |
phosphorylation |
Ser260 |
mouse |
acute lung injury (ALI) |
|
Forsythiae Fructuse (FF) |
modulate |
4.0 |
35483561 |
acc4826 |
Akt |
phosphorylation |
Ser473 |
rat |
diabetic |
|
P-Cymene |
modulate |
4.0 |
35528246 |
acc4827 |
AMPK |
phosphorylation |
Thr172 |
human |
diabetic |
|
metformin |
modulate |
4.0 |
35605453 |
acc4828 |
AMPK |
phosphorylation |
Thr183 |
human |
diabetic |
|
metformin |
modulate |
4.0 |
35605453 |
acc4829 |
Eralpha |
phosphorylation |
Ser118 |
human |
ovarian endometriosis |
Ishikawa cells |
E2 |
modulate |
4.0 |
35654737 |
acc4830 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
colorectal cancer |
MC38 |
Gallic acid |
modulate |
4.0 |
35817479 |
acc4831 |
Drp1 |
phosphorylation |
Ser616 |
mouse |
cardiac dysfunction |
|
Fasudil |
modulate |
4.0 |
35865967 |
acc4832 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
diabetic |
|
shIGFBP5 |
modulate |
3.0 |
35866351 |
acc4833 |
albumin |
glycosylation |
unclear |
human |
diabetic nephropathy |
HEK¨C293T |
high glucose |
modulate |
4.0 |
35987363 |
acc4834 |
AMPK |
phosphorylation |
Thr172 |
human |
endothelial cell angiogenic damage |
HUVECs |
CoCl2 |
modulate |
4.0 |
35994824 |
acc4835 |
AMPK |
phosphorylation |
Thr183 |
human |
endothelial cell angiogenic damage |
HUVECs |
CoCl2 |
modulate |
4.0 |
35994824 |
acc4836 |
PLN |
phosphorylation |
Ser16 |
human |
endothelial cell angiogenic damage |
HUVECs |
CoCl2 |
modulate |
4.0 |
35994824 |
acc4837 |
PLN |
phosphorylation |
Thr17 |
human |
endothelial cell angiogenic damage |
HUVECs |
CoCl2 |
modulate |
4.0 |
35994824 |
acc4838 |
Smad3 |
phosphorylation |
Ser423 |
rat |
cardiac inflammation and fibrosis |
T2DM rat |
Gentiopicroside |
modulate |
4.0 |
36037771 |
acc4839 |
Smad3 |
phosphorylation |
Ser425 |
rat |
cardiac inflammation and fibrosis |
T2DM rat |
Gentiopicroside |
modulate |
4.0 |
36037771 |
acc4840 |
alpha-synuclein |
phosphorylation |
Ser129 |
human |
Parkinson's disease |
|
PFE-360 |
modulate |
4.0 |
36179692 |
acc4841 |
alpha-synuclein |
phosphorylation |
Ser129 |
human |
Parkinson's disease |
|
MLi-2 |
modulate |
4.0 |
36179692 |
acc4842 |
Akt |
phosphorylation |
Ser437 |
mouse |
mitochondrial dysfunction |
|
Akap1 knockout |
modulate |
3.0 |
36263130 |
acc4843 |
Drp1 |
phosphorylation |
Ser637 |
mouse |
mitochondrial dysfunction |
|
Akap1 knockout |
modulate |
3.0 |
36263130 |
acc4844 |
Akt |
phosphorylation |
Ser473 |
rat |
metabolic disease |
|
CHM-273S |
modulate |
4.0 |
36297523 |
acc4845 |
Akt |
phosphorylation |
Thr308 |
rat |
metabolic disease |
|
CHM-273S |
modulate |
4.0 |
36297523 |
acc4846 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
asthma |
|
PQQ |
modulate |
4.0 |
36345503 |
acc4847 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
asthma |
|
PQQ |
modulate |
4.0 |
36345503 |
acc4848 |
STAT4 |
phosphorylation |
Tyr693 |
mouse |
asthma |
|
PQQ |
modulate |
4.0 |
36345503 |
acc4849 |
STAT6 |
phosphorylation |
Tyr641 |
mouse |
asthma |
|
PQQ |
modulate |
4.0 |
36345503 |
acc4850 |
p53 |
phosphorylation |
Ser46 |
human |
Cerebral ischemia-reperfusion injury (CIRI) |
SH-SY5Y |
DhHP-3 |
modulate |
4.0 |
36442518 |
acc4851 |
p53 |
phosphorylation |
Ser46 |
rat |
Cerebral ischemia-reperfusion injury (CIRI) |
|
DhHP-3 |
modulate |
4.0 |
36442518 |
acc4852 |
ERK1 |
phosphorylation |
Thr202 |
human |
mitochondrial dysfunction |
SH-SY5Y |
gallic acid |
modulate |
4.0 |
36563952 |
acc4853 |
ERK1 |
phosphorylation |
Tyr204 |
human |
mitochondrial dysfunction |
SH-SY5Y |
gallic acid |
modulate |
4.0 |
36563952 |
acc4854 |
ERK2 |
phosphorylation |
Thr185 |
human |
mitochondrial dysfunction |
SH-SY5Y |
gallic acid |
modulate |
4.0 |
36563952 |
acc4855 |
ERK2 |
phosphorylation |
Tyr187 |
human |
mitochondrial dysfunction |
SH-SY5Y |
gallic acid |
modulate |
4.0 |
36563952 |
acc4856 |
CaMKII |
phosphorylation |
Thr287 |
mouse |
diabetic |
|
EMPA |
modulate |
4.0 |
36607794 |
acc4857 |
RyR2 |
phosphorylation |
Ser2814 |
mouse |
diabetic |
|
EMPA |
modulate |
4.0 |
36607794 |
acc4858 |
IRS1 |
phosphorylation |
Ser307 |
mouse |
metabolic syndrome |
|
Platycodon grandiflorusroot extract |
modulate |
4.0 |
36610135 |
acc4859 |
WNK1 |
phosphorylation |
Thr58 |
mouse |
Clostridioides difficile infection (CDI) |
c57BL/6J mouse |
Genistein |
modulate |
4.0 |
36628948 |
acc4860 |
Akt |
phosphorylation |
unclear |
rat |
myocardial injury |
|
Diazoxide |
modulate |
4.0 |
36747448 |
acc4861 |
mTOR |
phosphorylation |
Ser2448 |
rat |
myocardial injury |
|
Diazoxide |
modulate |
4.0 |
36747448 |
acc4862 |
JNK |
phosphorylation |
unclear |
mouse |
cardiac inflammation |
|
C66 |
modulate |
4.0 |
36868294 |
acc4863 |
JNK |
phosphorylation |
unclear |
rat |
cardiac inflammation |
H9C2 |
C66 |
modulate |
4.0 |
36868294 |
acc4864 |
Cav3 |
nitration |
Tyr73 |
mouse |
diabetic |
|
SIN-1 |
modulate |
4.0 |
36883479 |
acc4865 |
ACC |
phosphorylation |
Ser79 |
mouse |
Hepatic lipid accumulation |
FL83B |
EF-2001 |
modulate |
4.0 |
36901915 |
acc4866 |
AMPK |
phosphorylation |
unclear |
mouse |
Hepatic lipid accumulation |
FL83B |
EF-2001 |
modulate |
4.0 |
36901915 |
acc4867 |
p70S6K |
phosphorylation |
Ser389 |
rat |
Cardiac hypertrophy |
NNVMs |
Rapamycin |
modulate |
4.0 |
36988388 |
acc4868 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
neurological damage |
|
HNK |
modulate |
4.0 |
36997099 |
acc4869 |
PPARgamma |
ubiquitination |
unclear |
mouse |
cardiac hypertrophy |
|
luteolin |
modulate |
4.0 |
36998980 |
acc4870 |
Jak1 |
ubiquitination |
unclear |
mouse |
cardiac hypertrophy |
|
Trim65 OE |
modulate |
3.0 |
37080331 |
acc4871 |
Akt |
phosphorylation |
unclear |
rat |
diabetic retinopathy |
|
Methylene blue |
modulate |
4.0 |
37248837 |
acc4872 |
ERK1 |
phosphorylation |
Thr202 |
rat |
diabetic retinopathy |
|
Methylene blue |
modulate |
4.0 |
37248837 |
acc4873 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
diabetic retinopathy |
|
Methylene blue |
modulate |
4.0 |
37248837 |
acc4874 |
ERK2 |
phosphorylation |
Thr185 |
rat |
diabetic retinopathy |
|
Methylene blue |
modulate |
4.0 |
37248837 |
acc4875 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
diabetic retinopathy |
|
Methylene blue |
modulate |
4.0 |
37248837 |
acc4876 |
EGFR |
phosphorylation |
Tyr1086 |
rat |
colitis |
|
EPA |
modulate |
4.0 |
37263490 |
acc4877 |
p53 |
acetylation |
Lys382 |
mouse |
acute kidney injury (AKI) |
|
Baicalein |
modulate |
4.0 |
37354967 |
acc4878 |
eIF2alpha |
phosphorylation |
Ser51 |
rat |
neuronal injury |
|
ISRIB |
modulate |
4.0 |
37410333 |
acc4879 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
colitis |
RAW 264.7 |
Loganic acid |
modulate |
4.0 |
37421777 |
acc4880 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
colitis |
Caco-2 |
Loganic acid |
modulate |
4.0 |
37421777 |
acc4881 |
eNOS |
phosphorylation |
Ser1177 |
human |
High glucose |
HUVECs |
TEPP-46 |
modulate |
4.0 |
37539568 |
acc4882 |
eNOS |
phosphorylation |
Ser1177 |
mouse |
diabetic macroangiopathy |
|
TEPP-46 |
modulate |
4.0 |
37539568 |
acc4883 |
PKM2 |
phosphorylation |
Tyr105 |
human |
High glucose |
HUVECs |
TEPP-46 |
modulate |
4.0 |
37539568 |
acc4884 |
PKM2 |
phosphorylation |
Tyr105 |
mouse |
diabetic macroangiopathy |
|
TEPP-46 |
modulate |
4.0 |
37539568 |
acc4885 |
PLB |
phosphorylation |
Thr17 |
mouse |
cardiac dysfunction |
|
Vidarabine |
modulate |
4.0 |
37558983 |
acc4886 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
head-twitch response (HTR) |
HEK293T |
M100907 + gallein |
modulate |
4.0 |
37657742 |
acc4887 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
head-twitch response (HTR) |
HEK293T |
M100907 + gallein |
modulate |
4.0 |
37657742 |
acc4888 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
head-twitch response (HTR) |
HEK293T |
M100907 + gallein |
modulate |
4.0 |
37657742 |
acc4889 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
head-twitch response (HTR) |
HEK293T |
M100907 + gallein |
modulate |
4.0 |
37657742 |
acc4890 |
PLCbeta3 |
phosphorylation |
Ser537 |
mouse |
head-twitch response (HTR) |
HEK293T |
M100907 + gallein |
modulate |
4.0 |
37657742 |
acc4891 |
STAT3 |
phosphorylation |
Ser727 |
mouse |
diabetic nephropathy |
|
Melatonin |
modulate |
4.0 |
37739161 |
acc4892 |
FRS2 |
phosphorylation |
Ser |
rat |
neuronal differentiation |
PC-12 |
U0126 |
modulate |
2.0 |
19652666 |
acc4893 |
FRS2 |
phosphorylation |
Thr |
rat |
neuronal differentiation |
PC-12 |
U0126 |
modulate |
2.0 |
19652666 |
acc4894 |
FRS2 |
phosphorylation |
Ser |
rat |
neuronal differentiation |
PC-12 |
POV |
modulate |
2.0 |
19652666 |
acc4895 |
FRS2 |
phosphorylation |
Thr |
rat |
neuronal differentiation |
PC-12 |
POV |
modulate |
2.0 |
19652666 |
acc4896 |
GSK3beta |
phosphorylation |
Ser9 |
mouse |
Melioidosis |
|
chloroquine+ doxycycline |
modulate |
4.0 |
33612800 |
acc4897 |
STAT3 |
phosphorylation |
Tyr705 |
human |
Psoriasis |
HaCaT |
Acitretin-conjugated dextran nanoparticles (ACT-Dex NPs) |
modulate |
3.0 |
35071218 |
acc4898 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
Psoriasis |
|
Tofacitinib |
modulate |
4.0 |
34626614 |
acc4899 |
STAT3 |
phosphorylation |
Ser727 |
human |
Psoriasis |
|
Curcumin |
modulate |
4.0 |
32114280 |
acc4900 |
STAT3 |
phosphorylation |
Ser727 |
human |
Psoriasis |
|
Curcumin |
modulate |
4.0 |
32114280 |
acc4901 |
STAT3 |
phosphorylation |
unclear |
mouse |
Psoriasis |
|
A-770041 |
modulate |
4.0 |
35576719 |
acc4902 |
GSK3beta |
phosphorylation |
Ser9 |
rat |
psychiatric disorders |
|
Lithium |
modulate |
4.0 |
29449801 |
acc4903 |
beta-catenin |
phosphorylation |
Ser33 |
rat |
psychiatric disorders |
|
Lithium |
modulate |
4.0 |
29449801 |
acc4904 |
beta-catenin |
phosphorylation |
Ser37 |
rat |
psychiatric disorders |
|
Lithium |
modulate |
4.0 |
29449801 |
acc4905 |
beta-catenin |
phosphorylation |
Thr41 |
rat |
psychiatric disorders |
|
Lithium |
modulate |
4.0 |
29449801 |
acc4906 |
eNOS |
phosphorylation |
Thr495 |
rat |
pulmonary thromboembolism |
|
Geldanamycin |
modulate |
4.0 |
18852069 |
acc4907 |
Tau |
phosphorylation |
Ser202 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4908 |
Tau |
phosphorylation |
Thr205 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4909 |
Tau |
phosphorylation |
Ser396 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4910 |
NR2B |
phosphorylation |
Tyr1472 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4911 |
Akt |
phosphorylation |
Thr308 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4912 |
PTEN |
phosphorylation |
Ser380 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4913 |
PTEN |
phosphorylation |
Thr382 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4914 |
PTEN |
phosphorylation |
Thr383 |
rat |
cognitive decline |
|
BPV (pic) |
modulate |
4.0 |
27836791 |
acc4915 |
Akt |
phosphorylation |
Ser473 |
mouse |
melanoma |
|
selumetinib |
inhibit |
5.0 |
27196754 |
acc4916 |
Akt |
phosphorylation |
Thr308 |
mouse |
melanoma |
|
selumetinib |
inhibit |
5.0 |
27196754 |
acc4917 |
Akt |
phosphorylation |
Ser473 |
mouse |
melanoma |
|
vemurafenib |
inhibit |
5.0 |
27196754 |
acc4918 |
Akt |
phosphorylation |
Thr308 |
mouse |
melanoma |
|
vemurafenib |
inhibit |
5.0 |
27196754 |
acc4919 |
Akt |
phosphorylation |
Thr308 |
rat |
pulmonary artery proliferation |
|
KMUP-1 |
modulate |
4.0 |
20870034 |
acc4920 |
ERK1 |
phosphorylation |
Thr202 |
rat |
pulmonary artery proliferation |
|
KMUP-1 |
modulate |
4.0 |
20870034 |
acc4921 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
pulmonary artery proliferation |
|
KMUP-1 |
modulate |
4.0 |
20870034 |
acc4922 |
ERK2 |
phosphorylation |
Thr185 |
rat |
pulmonary artery proliferation |
|
KMUP-1 |
modulate |
4.0 |
20870034 |
acc4923 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
pulmonary artery proliferation |
|
KMUP-1 |
modulate |
4.0 |
20870034 |
acc4924 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
pulmonary carcinomas |
|
U0126 |
modulate |
4.0 |
24947959 |
acc4925 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
pulmonary carcinomas |
|
U0126 |
modulate |
4.0 |
24947959 |
acc4926 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
pulmonary carcinomas |
|
U0126 |
modulate |
4.0 |
24947959 |
acc4927 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
pulmonary carcinomas |
|
U0126 |
modulate |
4.0 |
24947959 |
acc4928 |
MERTK |
phosphorylation |
Tyr749 |
human |
Thrombosis |
|
UNC2025 |
modulate |
4.0 |
29045015 |
acc4929 |
MERTK |
phosphorylation |
Tyr753 |
human |
Thrombosis |
|
UNC2025 |
modulate |
4.0 |
29045015 |
acc4930 |
MERTK |
phosphorylation |
Tyr754 |
human |
Thrombosis |
|
UNC2025 |
modulate |
4.0 |
29045015 |
acc4931 |
SRC |
phosphorylation |
Tyr416 |
human |
Thrombosis |
|
UNC2025 |
modulate |
4.0 |
29045015 |
acc4932 |
Akt |
phosphorylation |
Ser473 |
human |
Thrombosis |
|
UNC2025 |
modulate |
4.0 |
29045015 |
acc4935 |
SMAD2 |
phosphorylation |
Ser465 |
mouse |
Pulmonary hypertension |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4936 |
SMAD2 |
phosphorylation |
Ser467 |
mouse |
Pulmonary hypertension |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4937 |
SMAD3 |
phosphorylation |
Ser423 |
mouse |
Pulmonary hypertension |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4938 |
SMAD3 |
phosphorylation |
Ser425 |
mouse |
Pulmonary hypertension |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4939 |
SMAD2 |
phosphorylation |
Ser465 |
mouse |
pulmonary fibrosis |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4940 |
SMAD2 |
phosphorylation |
Ser467 |
mouse |
pulmonary fibrosis |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4941 |
SMAD3 |
phosphorylation |
Ser423 |
mouse |
pulmonary fibrosis |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4942 |
SMAD3 |
phosphorylation |
Ser425 |
mouse |
pulmonary fibrosis |
|
fasudil |
modulate |
4.0 |
23928001 |
acc4944 |
Akt |
phosphorylation |
unclear |
rat |
Pulmonary hypertension |
|
17beta-oestradiol |
modulate |
4.0 |
22936708 |
acc4945 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
Pulmonary hypertension |
|
delta-aminolevulinic acid (ALA) |
modulate |
4.0 |
25659899 |
acc4947 |
VASP |
phosphorylation |
unclear |
mouse |
Pulmonary hypertension |
|
delta-aminolevulinic acid (ALA) |
modulate |
4.0 |
24920729 |
acc4948 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
chronic obstructive pulmonary disease (COPD) |
|
Mahuang-Tang water extract (MTWE) |
modulate |
4.0 |
31004880 |
acc4949 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
chronic obstructive pulmonary disease (COPD) |
|
Mahuang-Tang water extract (MTWE) |
modulate |
4.0 |
31004880 |
acc4950 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
chronic obstructive pulmonary disease (COPD) |
|
Mahuang-Tang water extract (MTWE) |
modulate |
4.0 |
31004880 |
acc4951 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
chronic obstructive pulmonary disease (COPD) |
|
Mahuang-Tang water extract (MTWE) |
modulate |
4.0 |
31004880 |
acc4953 |
p70s6k |
phosphorylation |
Thr389 |
human |
Rheumatoid arthritis (RA) |
|
Metformin |
modulate |
4.0 |
31028998 |
acc4954 |
4E-BP1 |
phosphorylation |
Thr37 |
human |
Rheumatoid arthritis (RA) |
|
Metformin |
modulate |
4.0 |
31028998 |
acc4955 |
4E-BP1 |
phosphorylation |
Thr46 |
human |
Rheumatoid arthritis (RA) |
|
Metformin |
modulate |
4.0 |
31028998 |
acc4957 |
EGFR |
oxidation |
Cys797 |
human |
retinoblastoma (Rb) |
Y-79 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4958 |
EGFR |
phosphorylation |
Tyr1068 |
human |
retinoblastoma (Rb) |
Y-79 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4959 |
VAV2 |
phosphorylation |
Tyr |
human |
retinoblastoma (Rb) |
Y-79 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4960 |
SRC |
phosphorylation |
Tyr416 |
human |
retinoblastoma (Rb) |
Y-79 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4961 |
EGFR |
oxidation |
Cys797 |
human |
retinoblastoma (Rb) |
WERI-Rb-1 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4962 |
EGFR |
phosphorylation |
Tyr1068 |
human |
retinoblastoma (Rb) |
WERI-Rb-1 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4963 |
VAV2 |
phosphorylation |
Tyr |
human |
retinoblastoma (Rb) |
WERI-Rb-1 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4964 |
SRC |
phosphorylation |
Tyr416 |
human |
retinoblastoma (Rb) |
WERI-Rb-1 |
Tubeimoside II (TBMS II) |
modulate |
4.0 |
33412154 |
acc4965 |
EGFR |
sulfenylation |
Cys797 |
human |
lung cancer |
H292 |
DUOX1 KO |
modulate |
3.0 |
30890751 |
acc4966 |
EGFR |
sulfenylation |
Cys797 |
human |
lung cancer |
H187 |
DUOX1 KO |
modulate |
3.0 |
30890751 |
acc4967 |
EGFR |
sulfenylation |
Cys797 |
human |
lung cancer |
A549 |
DUOX1 KO |
modulate |
3.0 |
30890751 |
acc4968 |
EGFR |
sulfenylation |
Cys797 |
human |
lung cancer |
A549 |
Cetuximab |
enhance |
5.0 |
30890751 |
acc4969 |
EGFR |
sulfenylation |
Cys797 |
human |
lung cancer |
A549 |
erlotinib |
enhance |
5.0 |
30890751 |
acc4970 |
EGFR |
S-glutathionylation |
Cys797 |
human |
lung cancer |
A549 |
Cetuximab |
enhance |
5.0 |
30890751 |
acc4971 |
EGFR |
S-glutathionylation |
Cys797 |
human |
lung cancer |
A549 |
erlotinib |
enhance |
5.0 |
30890751 |
acc4972 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4973 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4974 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4975 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4976 |
Rb |
phosphorylation |
Ser807 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4977 |
Rb |
phosphorylation |
Ser811 |
mouse |
retinoblastoma |
MA-10 |
FGF9 |
modulate |
3.0 |
30191630 |
acc4981 |
DR5 |
ubiquitination |
unclear |
human |
renal carcinoma |
Caki-1 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4982 |
DR5 |
ubiquitination |
unclear |
human |
renal carcinoma |
ACHN |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4983 |
DR5 |
ubiquitination |
unclear |
human |
renal carcinoma |
A498 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4984 |
DR5 |
ubiquitination |
unclear |
human |
lung cancer |
A549 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4985 |
DR5 |
ubiquitination |
unclear |
human |
breast cancer |
MCF7 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4986 |
Survivin |
ubiquitination |
unclear |
human |
renal carcinoma |
Caki-1 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4987 |
Survivin |
ubiquitination |
unclear |
human |
renal carcinoma |
ACHN |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4988 |
Survivin |
ubiquitination |
unclear |
human |
renal carcinoma |
A498 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4989 |
Survivin |
ubiquitination |
unclear |
human |
lung cancer |
A549 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4990 |
Survivin |
ubiquitination |
unclear |
human |
breast cancer |
MCF7 |
IITZ-01 |
enhance |
5.0 |
32825566 |
acc4998 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
nonseptic shock |
|
tyrphostin AG-490 |
modulate |
4.0 |
18656556 |
acc4999 |
STAT1 |
phosphorylation |
Tyr701 |
mouse |
nonseptic shock |
|
tyrphostin AG-490 |
modulate |
4.0 |
18656556 |
acc5000 |
DDR1 |
phosphorylation |
Tyr |
mouse |
renal fibrosis |
|
compound2.45 |
modulate |
4.0 |
30452219 |
acc5001 |
Src |
phosphorylation |
Tyr416 |
human |
renal fibrosis |
HK-2 |
GW4064 |
modulate |
4.0 |
31298930 |
acc5002 |
YAP |
phosphorylation |
Ser127 |
human |
renal fibrosis |
HK-2 |
GW4064 |
modulate |
4.0 |
31298930 |
acc5003 |
Lats1 |
phosphorylation |
Ser909 |
human |
renal fibrosis |
HK-2 |
GW4064 |
modulate |
4.0 |
31298930 |
acc5004 |
Src |
phosphorylation |
Tyr416 |
human |
renal fibrosis |
HK-2 |
PP2 |
modulate |
4.0 |
31298930 |
acc5005 |
EGFR |
phosphorylation |
Tyr845 |
human |
renal fibrosis |
HK-2 |
PP2 |
modulate |
4.0 |
31298930 |
acc5006 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
renal fibrosis |
|
telmisartan |
modulate |
4.0 |
21381899 |
acc5007 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
renal fibrosis |
|
telmisartan |
modulate |
4.0 |
21381899 |
acc5008 |
MAPKAPK-2 |
phosphorylation |
unclear |
mouse |
renal fibrosis |
|
telmisartan |
modulate |
4.0 |
21381899 |
acc5009 |
Akt |
phosphorylation |
unclear |
mouse |
renal fibrosis |
|
telmisartan |
modulate |
4.0 |
21381899 |
acc5010 |
Smad3 |
phosphorylation |
Ser423 |
mouse |
renal fibrosis |
|
BT173 |
modulate |
4.0 |
28220029 |
acc5011 |
Smad3 |
phosphorylation |
Ser425 |
mouse |
renal fibrosis |
|
BT173 |
modulate |
4.0 |
28220029 |
acc5013 |
MGMT |
methylation |
unclear |
rat |
liver cancer |
|
thyroxine |
modulate |
4.0 |
6825117 |
acc5017 |
AMPK |
phosphorylation |
Thr183 |
mouse |
renal injury |
|
14(15)-EET |
modulate |
4.0 |
30804206 |
acc5018 |
AMPK |
phosphorylation |
Thr172 |
mouse |
renal injury |
|
14(15)-EET |
modulate |
4.0 |
30804206 |
acc5019 |
AMPK |
phosphorylation |
Thr183 |
mouse |
renal injury |
|
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea |
modulate |
4.0 |
30804206 |
acc5020 |
AMPK |
phosphorylation |
Thr172 |
mouse |
renal injury |
|
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea |
modulate |
4.0 |
30804206 |
acc5021 |
Pax2 |
phosphorylation |
Ser393 |
mouse |
renal injury |
|
14(15)-EET |
modulate |
4.0 |
30804206 |
acc5022 |
Pax2 |
phosphorylation |
Ser393 |
mouse |
renal injury |
|
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea |
modulate |
4.0 |
30804206 |
acc5023 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
renal interstitial fibrosis |
|
resveratrol |
modulate |
4.0 |
24976155 |
acc5024 |
STAT3 |
acetylation |
Lys685 |
mouse |
renal interstitial fibrosis |
|
resveratrol |
modulate |
4.0 |
24976155 |
acc5025 |
STAT3 |
phosphorylation |
Tyr705 |
rat |
renal interstitial fibrosis |
NRK-52E |
resveratrol |
modulate |
4.0 |
24976155 |
acc5026 |
STAT3 |
acetylation |
Lys685 |
rat |
renal interstitial fibrosis |
NRK-52E |
resveratrol |
modulate |
4.0 |
24976155 |
acc5027 |
SMAD2 |
phosphorylation |
unclear |
rat |
Cardiorenal syndrome (CRS) |
|
G226 |
modulate |
4.0 |
32305147 |
acc5030 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
rat |
renal injury |
|
Benazepril |
modulate |
4.0 |
19018797 |
acc5036 |
VEGFR-2 |
phosphorylation |
Tyr1175 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5037 |
Src |
phosphorylation |
Tyr416 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5038 |
FAK |
phosphorylation |
Tyr576 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5039 |
FAK |
phosphorylation |
Tyr577 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5040 |
ERK1 |
phosphorylation |
Thr202 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5041 |
ERK1 |
phosphorylation |
Tyr204 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5042 |
ERK2 |
phosphorylation |
Thr185 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5043 |
ERK2 |
phosphorylation |
Try187 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5044 |
AKT |
phosphorylation |
Ser473 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5045 |
mTOR |
phosphorylation |
Ser2448 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5046 |
p70S6K |
phosphorylation |
Thr389 |
human |
neovascular eye disease |
HUVECs |
Curcumolide |
modulate |
4.0 |
31450226 |
acc5047 |
retinoblastoma protein (Rb) |
phosphorylation |
Ser807 |
mouse |
diabetes |
|
PKG-OE |
modulate |
3.0 |
19717728 |
acc5048 |
retinoblastoma protein (Rb) |
phosphorylation |
Ser811 |
mouse |
diabetes |
|
PKG-OE |
modulate |
3.0 |
19717728 |
acc5049 |
VASP |
phosphorylation |
Ser239 |
mouse |
diabetes |
|
PKG-OE |
modulate |
3.0 |
19717728 |
acc5050 |
STAT3 |
phosphorylation |
Tyr705 |
human |
rheumatoid arthritis |
|
KD025 |
modulate |
4.0 |
25385601 |
acc5051 |
STAT5 |
phosphorylation |
Tyr694 |
human |
rheumatoid arthritis |
|
KD025 |
modulate |
4.0 |
25385601 |
acc5052 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
rheumatoid arthritis |
|
KD025 |
modulate |
4.0 |
25385601 |
acc5053 |
STAT5 |
phosphorylation |
Tyr694 |
mouse |
rheumatoid arthritis |
|
KD025 |
modulate |
4.0 |
25385601 |
acc5054 |
ERK1 |
phosphorylation |
Thr202 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5055 |
ERK1 |
phosphorylation |
Tyr204 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5056 |
ERK2 |
phosphorylation |
Thr185 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5057 |
ERK2 |
phosphorylation |
Tyr187 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5058 |
p38 MAPK |
phosphorylation |
Thr180 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5059 |
p38 MAPK |
phosphorylation |
Tyr182 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5060 |
JNK1 |
phosphorylation |
Thr183 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5061 |
JNK1 |
phosphorylation |
Tyr185 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5062 |
JNK2 |
phosphorylation |
Thr183 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5063 |
JNK2 |
phosphorylation |
Tyr185 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5064 |
PKCmiu |
phosphorylation |
Ser744 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5065 |
PKCmiu |
phosphorylation |
Ser748 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5066 |
IkappaBalpha |
phosphorylation |
Ser32 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5067 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5068 |
c-Jun |
phosphorylation |
Ser63 |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5069 |
c-Fos |
phosphorylation |
unclear |
human |
rheumatoid arthritis |
|
Bradykinin (BK) |
modulate |
4.0 |
28288820 |
acc5070 |
c-Jun |
acetylation |
unclear |
human |
rheumatoid arthritis |
|
Resveratrol |
modulate |
4.0 |
28288820 |
acc5071 |
c-Fos |
acetylation |
unclear |
human |
rheumatoid arthritis |
|
Resveratrol |
modulate |
4.0 |
28288820 |
acc5072 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
human |
rheumatoid arthritis |
|
Resveratrol |
modulate |
4.0 |
28288820 |
acc5073 |
c-Jun |
phosphorylation |
Ser63 |
human |
rheumatoid arthritis |
|
Resveratrol |
modulate |
4.0 |
28288820 |
acc5074 |
c-Fos |
phosphorylation |
unclear |
human |
rheumatoid arthritis |
|
Resveratrol |
modulate |
4.0 |
28288820 |
acc5075 |
STAT1 |
phosphorylation |
Tyr701 |
human |
rheumatoid arthritis |
|
Tofacitinib |
modulate |
4.0 |
25398374 |
acc5076 |
STAT3 |
phosphorylation |
Tyr705 |
human |
rheumatoid arthritis |
|
Tofacitinib |
modulate |
4.0 |
25398374 |
acc5083 |
MLC2 |
phosphorylation |
Ser19 |
rat |
subarachnoid hemorrhage (SAH) |
|
SNX-482 |
modulate |
4.0 |
20568961 |
acc5085 |
EGFR |
phosphorylation |
Tyr1068 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5086 |
VEGFR-2 |
phosphorylation |
Tyr1054 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5087 |
Akt |
phosphorylation |
Ser473 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5088 |
ERK1 |
phosphorylation |
Thr202 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5089 |
ERK1 |
phosphorylation |
Tyr204 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5090 |
ERK2 |
phosphorylation |
Thr202 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5091 |
ERK2 |
phosphorylation |
Tyr204 |
human |
salivary adenoid cystic carcinoma (ACC) |
ACC3 |
AEE788 |
modulate |
4.0 |
17121916 |
acc5095 |
ERK1 |
phosphorylation |
Thr202 |
rat |
spinal cord injury (SCI) |
|
PD98059 |
modulate |
4.0 |
16513110 |
acc5096 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
spinal cord injury (SCI) |
|
PD98059 |
modulate |
4.0 |
16513110 |
acc5097 |
ERK2 |
phosphorylation |
Thr185 |
rat |
spinal cord injury (SCI) |
|
PD98059 |
modulate |
4.0 |
16513110 |
acc5098 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
spinal cord injury (SCI) |
|
PD98059 |
modulate |
4.0 |
16513110 |
acc5099 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
spinal cord injury (SCI) |
|
Ruxolitinib |
modulate |
4.0 |
30899259 |
acc5100 |
JNK1 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
SP600125 |
modulate |
4.0 |
27080425 |
acc5101 |
JNK1 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
SP600125 |
modulate |
4.0 |
27080425 |
acc5102 |
JNK2 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
SP600125 |
modulate |
4.0 |
27080425 |
acc5103 |
JNK2 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
SP600125 |
modulate |
4.0 |
27080425 |
acc5104 |
histone H3 |
acetylation |
unclear |
human |
lung cancer |
U1906 |
Decitabine + VPA |
modulate |
3.0 |
21771726 |
acc5105 |
histone H3 |
acetylation |
unclear |
human |
lung cancer |
H2171 |
Decitabine + VPA |
modulate |
3.0 |
21771726 |
acc5106 |
Akt |
phosphorylation |
Ser473 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5107 |
Ribosomal protein S6 |
phosphorylation |
Ser235 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5108 |
Ribosomal protein S6 |
phosphorylation |
Ser236 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5109 |
ERK1 |
phosphorylation |
Thr202 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5110 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5111 |
ERK2 |
phosphorylation |
Thr185 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5112 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
spinal cord injury (SCI) |
|
bisperoxovanadium (bpV) |
modulate |
4.0 |
30672370 |
acc5113 |
PKA |
phosphorylation |
Thr197 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5114 |
PP2B |
phosphorylation |
Ser197 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5115 |
ERK1 |
phosphorylation |
Thr202 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5116 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5117 |
ERK2 |
phosphorylation |
Thr185 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5118 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
status epilepticus |
|
Leptomycin B (LMB) |
modulate |
4.0 |
28601633 |
acc5119 |
ERK1 |
phosphorylation |
Thr202 |
rat |
status epilepticus |
|
Leptomycin B (LMB) + Cyclosporin A (CsA) |
modulate |
4.0 |
28601633 |
acc5120 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
status epilepticus |
|
Leptomycin B (LMB) + Cyclosporin A (CsA) |
modulate |
4.0 |
28601633 |
acc5121 |
ERK2 |
phosphorylation |
Thr185 |
rat |
status epilepticus |
|
Leptomycin B (LMB) + Cyclosporin A (CsA) |
modulate |
4.0 |
28601633 |
acc5122 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
status epilepticus |
|
Leptomycin B (LMB) + Cyclosporin A (CsA) |
modulate |
4.0 |
28601633 |
acc5123 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5124 |
ERK1 |
phosphorylation |
Thr202 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5125 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5126 |
ERK2 |
phosphorylation |
Thr185 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5127 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5128 |
JNK1 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5129 |
JNK1 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5130 |
JNK2 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5131 |
JNK2 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5132 |
p38 MAPK |
phosphorylation |
Thr180 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5133 |
p38 MAPK |
phosphorylation |
Tyr182 |
rat |
spinal cord injury (SCI) |
|
C225 |
modulate |
4.0 |
22824323 |
acc5134 |
EGFR |
phosphorylation |
Tyr1068 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5135 |
ERK1 |
phosphorylation |
Thr202 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5136 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5137 |
ERK2 |
phosphorylation |
Thr185 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5138 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5139 |
JNK1 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5140 |
JNK1 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5141 |
JNK2 |
phosphorylation |
Thr183 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5142 |
JNK2 |
phosphorylation |
Tyr185 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5143 |
p38 MAPK |
phosphorylation |
Thr180 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5144 |
p38 MAPK |
phosphorylation |
Tyr182 |
rat |
spinal cord injury (SCI) |
|
AG1478 |
modulate |
4.0 |
22824323 |
acc5145 |
IRAK4 |
phosphorylation |
Thr345 |
mouse |
traumatic brain injury (TBI) |
|
PF-0665083 |
modulate |
4.0 |
35149117 |
acc5146 |
TAK1 |
phosphorylation |
unclear |
mouse |
traumatic brain injury (TBI) |
|
PF-0665083 |
modulate |
4.0 |
35149117 |
acc5147 |
IRAK4 |
phosphorylation |
Thr345 |
mouse |
traumatic brain injury (TBI) |
|
IRAK4 KO |
modulate |
3.0 |
35149117 |
acc5148 |
TAK1 |
phosphorylation |
unclear |
mouse |
traumatic brain injury (TBI) |
|
IRAK4 KO |
modulate |
3.0 |
35149117 |
acc5151 |
Akt |
phosphorylation |
unclear |
rat |
neuronal damage |
|
silymarin |
modulate |
4.0 |
33182349 |
acc5152 |
ERK1 |
phosphorylation |
Thr202 |
rat |
neuronal damage |
|
silymarin |
modulate |
4.0 |
33182349 |
acc5153 |
ERK1 |
phosphorylation |
Tyr204 |
rat |
neuronal damage |
|
silymarin |
modulate |
4.0 |
33182349 |
acc5154 |
ERK2 |
phosphorylation |
Thr185 |
rat |
neuronal damage |
|
silymarin |
modulate |
4.0 |
33182349 |
acc5155 |
ERK2 |
phosphorylation |
Tyr187 |
rat |
neuronal damage |
|
silymarin |
modulate |
4.0 |
33182349 |
acc5156 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
seizures |
|
topiramate (TPM) |
modulate |
4.0 |
17868053 |
acc5157 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
seizures |
|
topiramate (TPM) |
modulate |
4.0 |
17868053 |
acc5158 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
seizures |
|
topiramate (TPM) |
modulate |
4.0 |
17868053 |
acc5159 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
seizures |
|
topiramate (TPM) |
modulate |
4.0 |
17868053 |
acc5160 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
acute lung injury |
J774A.1 |
Colchicine |
modulate |
4.0 |
37115345 |
acc5161 |
Histone H3 |
acetylation |
unclear |
mouse |
acute lung injury |
J774A.1 |
Colchicine |
modulate |
3.0 |
37115345 |
acc5162 |
Histone H4 |
acetylation |
unclear |
mouse |
acute lung injury |
J774A.1 |
Colchicine |
modulate |
3.0 |
37115345 |
acc5163 |
cTnI |
phosphorylation |
Ser23 |
mouse |
Sepsis-associated cardiac dysfunction |
|
Cyclopentyladenosine |
modulate |
4.0 |
19201758 |
acc5164 |
cTnI |
phosphorylation |
Ser24 |
mouse |
Sepsis-associated cardiac dysfunction |
|
Cyclopentyladenosine |
modulate |
4.0 |
19201758 |
acc5165 |
PP2A |
methylation |
Leu309 |
mouse |
Sepsis-associated cardiac dysfunction |
|
LPS |
modulate |
3.0 |
19201758 |
acc5172 |
NF-kappaB p65 |
phosphorylation |
Ser536 |
mouse |
acute kidney injury (AKI) |
|
Dimethyl fumarate (DMF) |
modulate |
4.0 |
34915410 |
acc5173 |
ERK1 |
phosphorylation |
Thr202 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5174 |
ERK1 |
phosphorylation |
Tyr204 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5175 |
ERK2 |
phosphorylation |
Thr185 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5176 |
ERK2 |
phosphorylation |
Tyr187 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5177 |
p38 MAPK |
phosphorylation |
Thr180 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5178 |
p38 MAPK |
phosphorylation |
Tyr182 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5179 |
JNK1 |
phosphorylation |
Thr183 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5180 |
JNK1 |
phosphorylation |
Tyr185 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5181 |
JNK2 |
phosphorylation |
Thr183 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5182 |
JNK2 |
phosphorylation |
Tyr185 |
mouse |
cardiomyopathy |
|
hydrogen therapy |
modulate |
3.0 |
31440160 |
acc5183 |
STAT3 |
phosphorylation |
Tyr705 |
mouse |
cardiomyopathy |
|
Electroacupuncture (EA) |
modulate |
3.0 |
36160853 |