| acc2401 | 
            STAT6 | 
            phosphorylation | 
            Tyr641 | 
            human | 
            Breast Cancer | 
            EO771 | 
            Emodin | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              25311112
              
             | 
          
          
          
            | acc2402 | 
            H2AX | 
            methylation | 
            Lys134 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            Doxorubicin | 
            
            Impairing | 
            
            
            4.5 (High)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2403 | 
            H2AX | 
            phosphorylation | 
            Ser139 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            Doxorubicin | 
            
            Impairing | 
            
            
            4.5 (High)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2404 | 
            H2AX | 
            methylation | 
            Lys134 | 
            human | 
            Lung Cancer | 
            A549 | 
            Doxorubicin | 
            
            Impairing | 
            
            
            4.5 (High)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2405 | 
            H2AX | 
            phosphorylation | 
            Ser139 | 
            human | 
            Lung Cancer | 
            A549 | 
            Doxorubicin | 
            
            Impairing | 
            
            
            4.5 (High)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2406 | 
            H2AX | 
            methylation | 
            Lys134 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            OTS193320 | 
            
            Associated | 
            
            
            3.0 (Low)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2407 | 
            H2AX | 
            phosphorylation | 
            Ser139 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            OTS193320 | 
            
            Associated | 
            
            
            3.0 (Low)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2408 | 
            H2AX | 
            methylation | 
            Lys134 | 
            human | 
            Lung Cancer | 
            A549 | 
            OTS193320 | 
            
            Associated | 
            
            
            3.0 (Low)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2409 | 
            H2AX | 
            phosphorylation | 
            Ser139 | 
            human | 
            Lung Cancer | 
            A549 | 
            OTS193320 | 
            
            Associated | 
            
            
            3.0 (Low)
             | 
            
            
            
              
              30159125
              
             | 
          
          
          
            | acc2410 | 
            YAP | 
            phosphorylation | 
            Ser127 | 
            human | 
            Pancreas Cancer | 
            PANC-1 | 
            Gemcitabine | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31627466
              
             | 
          
          
          
            | acc2411 | 
            YAP | 
            phosphorylation | 
            Ser127 | 
            human | 
            Pancreas Cancer | 
            BxPC-3 | 
            Gemcitabine | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31627466
              
             | 
          
          
          
            | acc2412 | 
            YAP | 
            phosphorylation | 
            Ser127 | 
            human | 
            Pancreas Cancer | 
            ASPC-1 | 
            Gemcitabine | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31627466
              
             | 
          
          
          
            | acc2413 | 
            Bcl-2 | 
            phosphorylation | 
            unclear | 
            human | 
            Lung Cancer | 
            H5800 | 
            Cisplatin | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              24548862
              
             | 
          
          
          
            | acc2414 | 
            Bcl-2 | 
            phosphorylation | 
            unclear | 
            mouse | 
            Lung Cancer | 
            LKR | 
            Cisplatin | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              24548862
              
             | 
          
          
          
            | acc2415 | 
            Beclin-1 | 
            ubiquitination | 
            Ser90 | 
            human | 
            Myeloma | 
            KMS11 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2416 | 
            Beclin-1 | 
            ubiquitination | 
            Ser90 | 
            human | 
            Myeloma | 
            RPMI8226 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2417 | 
            Beclin-1 | 
            ubiquitination | 
            Ser93 | 
            human | 
            Myeloma | 
            KMS11 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2418 | 
            Beclin-1 | 
            ubiquitination | 
            Ser93 | 
            human | 
            Myeloma | 
            RPMI8226 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2419 | 
            Beclin-1 | 
            ubiquitination | 
            Ser96 | 
            human | 
            Myeloma | 
            KMS11 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2420 | 
            Beclin-1 | 
            ubiquitination | 
            Ser96 | 
            human | 
            Myeloma | 
            RPMI8226 | 
            BTZ | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              31955515
              
             | 
          
          
          
            | acc2421 | 
            MRE11 | 
            ubiquitination | 
            Lys339 | 
            human | 
            Breast Cancer | 
            HCC1806 | 
            Radiotherapy | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              36563124
              
             | 
          
          
          
            | acc2422 | 
            MRE11 | 
            ubiquitination | 
            Lys339 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            Radiotherapy | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              36563124
              
             | 
          
          
          
            | acc2423 | 
            MRE11 | 
            ubiquitination | 
            Lys480 | 
            human | 
            Breast Cancer | 
            HCC1806 | 
            Radiotherapy | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              36563124
              
             | 
          
          
          
            | acc2424 | 
            MRE11 | 
            ubiquitination | 
            Lys480 | 
            human | 
            Breast Cancer | 
            MDA-MB-231 | 
            Radiotherapy | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              36563124
              
             | 
          
          
          
            | acc2425 | 
            RIPK1 | 
            ubiquitination | 
            unclear | 
            human | 
            Leukemia | 
            MT4 | 
            Birinapant | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2426 | 
            CYLD | 
            phosphorylation | 
            Ser418 | 
            human | 
            Leukemia | 
            MT4 | 
            Birinapant | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2427 | 
            RIPK1 | 
            ubiquitination | 
            unclear | 
            human | 
            Leukemia | 
            MT4 | 
            MRT67307 | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2428 | 
            CYLD | 
            phosphorylation | 
            Ser418 | 
            human | 
            Leukemia | 
            MT4 | 
            MRT67307 | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2429 | 
            RIPK1 | 
            ubiquitination | 
            unclear | 
            human | 
            Leukemia | 
            MT4 | 
            TPCA | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2430 | 
            CYLD | 
            phosphorylation | 
            Ser418 | 
            human | 
            Leukemia | 
            MT4 | 
            TPCA | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              32024820
              
             | 
          
          
          
            | acc2431 | 
            ERK1 | 
            phosphorylation | 
            Thr202 | 
            human | 
            Hepatocellular Carcinoma | 
            Hep3B | 
            EGCG | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              19360302
              
             | 
          
          
          
            | acc2432 | 
            ERK1 | 
            phosphorylation | 
            Tyr204 | 
            human | 
            Hepatocellular Carcinoma | 
            Hep3B | 
            EGCG | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              19360302
              
             | 
          
          
          
            | acc2433 | 
            ERK2 | 
            phosphorylation | 
            Thr185 | 
            human | 
            Hepatocellular Carcinoma | 
            Hep3B | 
            EGCG | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              19360302
              
             | 
          
          
          
            | acc2434 | 
            ERK2 | 
            phosphorylation | 
            Tyr187 | 
            human | 
            Hepatocellular Carcinoma | 
            Hep3B | 
            EGCG | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              19360302
              
             | 
          
          
          
            | acc2435 | 
            NFKBIA | 
            phosphorylation | 
            Ser32 | 
            human | 
            Myeloma | 
            MM.1S | 
            PS-1145 | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              11872748
              
             | 
          
          
          
            | acc2436 | 
            NFKBIA | 
            phosphorylation | 
            Ser32 | 
            human | 
            Myeloma | 
            RPMI8226 | 
            PS-1145 | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              11872748
              
             | 
          
          
          
            | acc2437 | 
            NFKBIA | 
            phosphorylation | 
            Ser32 | 
            human | 
            Myeloma | 
            U266 | 
            PS-1145 | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              11872748
              
             | 
          
          
          
            | acc2438 | 
            NFKBIA | 
            phosphorylation | 
            Ser32 | 
            human | 
            Myeloma | 
            MM.1S | 
            PS-1145 + Dex | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              11872748
              
             | 
          
          
          
            | acc2439 | 
            TOPK | 
            phosphorylation | 
            Thr9 | 
            human | 
            Melanoma | 
            RPMI7951 | 
            arsenite | 
            
            Associated | 
            
            
            4.0 (Moderate) | 
            
            
            
              
              17145805
              
             | 
          
          
          
            | acc2440 | 
            H2AX | 
            phosphorylation | 
            Ser139 | 
            human | 
            Melanoma | 
            RPMI7951 | 
            arsenite | 
            
            Associated | 
            
            
            3.0 (Low)
             | 
            
            
            
              
              17145805
              
             | 
          
          
          
            | acc2441 | 
            AMPK | 
            phosphorylation | 
            Thr172 | 
            human | 
            Lung Cancer | 
            A549 | 
            TRAIL | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              29929000
              
             | 
          
          
          
            | acc2442 | 
            AMPK | 
            phosphorylation | 
            Thr183 | 
            human | 
            Lung Cancer | 
            A549 | 
            TRAIL | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              29929000
              
             | 
          
          
          
            | acc2443 | 
            AMPK | 
            phosphorylation | 
            Thr172 | 
            human | 
            Lung Cancer | 
            HCC-15 | 
            TRAIL | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              29929000
              
             | 
          
          
          
            | acc2444 | 
            AMPK | 
            phosphorylation | 
            Thr183 | 
            human | 
            Lung Cancer | 
            HCC-15 | 
            TRAIL | 
            
            Impairing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              29929000
              
             | 
          
          
          
            | acc2445 | 
            JNK2 | 
            phosphorylation | 
            Thr183 | 
            human | 
            Colorectal Cancer | 
            HT29 | 
            TRAIL + 5-fluorouracil (5-FU) | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             | 
          
          
          
            | acc2446 | 
            JNK2 | 
            phosphorylation | 
            Thr183 | 
            human | 
            Hepatocellular Carcinoma | 
            HepG2 | 
            TRAIL + 5-fluorouracil (5-FU) | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             | 
          
          
          
            | acc2447 | 
            JNK2 | 
            phosphorylation | 
            Tyr185 | 
            human | 
            Colorectal Cancer | 
            HT29 | 
            TRAIL + 5-fluorouracil (5-FU) | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             | 
          
          
          
            | acc2448 | 
            JNK2 | 
            phosphorylation | 
            Tyr185 | 
            human | 
            Hepatocellular Carcinoma | 
            HepG2 | 
            TRAIL + 5-fluorouracil (5-FU) | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             | 
          
          
          
            | acc2449 | 
            JNK2 | 
            phosphorylation | 
            Thr183 | 
            human | 
            Colorectal Cancer | 
            HT29 | 
            TRAIL + Cisplatin | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             | 
          
          
          
            | acc2450 | 
            JNK2 | 
            phosphorylation | 
            Thr183 | 
            human | 
            Hepatocellular Carcinoma | 
            HepG2 | 
            TRAIL + Cisplatin | 
            
            Enhancing | 
            
            
            5.0 (High)
             | 
            
            
            
              
              15837763
              
             |