scPharm-Web

Sample statistics

Sample statistics on cells, genes, UMIs, mitochondrial ratios, etc.

QC plot

Violin plots of genes, UMI for all cells in the sample.

Sample plot

Scatter plot of samples in UMAP showing all cells.

Cell clustering plot

The cell clustering plot is presented as a UMAP scatterplot.

scPharm specific drug analysis results

The results of the scPharm analyses (specified drugs or top-ranked drugs) are displayed in UMAP.

scPharm drugs ranking plot

A lollipop chart showing some of the drugs with the highest Dr scores, i.e., drug recommendation rankings.

scPharm drugs ranking plot (Combo mode)

A lollipop chart showing some of the drugs with the highest Dr scores, i.e., drug recommendation rankings.

Specific drug combinations

Combined drug analysis of specific drugs or top-ranked drugs, including compensatory and boosted effects.

Combination drugs of top-ranked drugs

Combined drug analysis of top-ranked drugs, including compensatory and potentiating effects.

Drug side effect ranking plot

Ranking of drug side effects on healthy cells, i.e., sensitive drug recommendations for healthy cells.

Immunotherapy score plot

The suitability of the samples for immunotherapy was inferred from the immunization scores calculated from CM-drugs, Tres and TIDE.

Cell meta table

A meta-informative table of cells with scPharm prediction results for each drug and Seurat basic analysis output.

Cell meta table for Combo mode

A meta-informative table of cells with scPharm prediction results for each drug and Seurat basic analysis output.

Drug combinations table

All top-ranked (user-specified) drug pairs.

Drug side effect table

Ranking of all drug side effects, manifested by the drug's sensitivity to healthy cells.

scPharm predicts table

scPharm's predicted drug recommendation ranking table, with higher Dr values indicating a more sensitive drug. Available only if DR_analysis is selected.

Immunotherapy score table

Immunization scores calculated from CM-drugs, Tres and TIDE.

Immunotherapy recommendation results table

Whether immunotherapy is recommended or not based on immunotherapy scores divided by certain thresholds.

scPharm predicts results

The scPharm predictions are saved as Seurat objects and the predictions for all drugs are contained in meta.data.

scPharm predicts results (Combo mode)

The scPharm predictions are saved as Seurat objects and the predictions for all drugs are contained in meta.data.

scPharm drug combination analysis results

scPharm drug combination analysis results are consistent with the drug combination table, but are stored as rds files.

scPharm top ranked drugs combination

scPharm top ranked drug combination analysis results are consistent with the Combination drugs of top-ranked drugs, but are stored as rds files.

scPharm drug side effect results

scPharm drug side effect results, consistent with the Drug side effect table, but stored as rds.