Id: acc0365
Group: 1sens
Protein: S6
Gene Symbol: RPS6
Protein Id: P62753
Protein Name: RS6_HUMAN
PTM: phosphorylation
Site: Ser240
Site Sequence: RRRLSSLRASTSKSESSQK--
Disease Category: Cancer
Disease: Glioblastoma
Disease Subtype:
Disease Cellline: U87-MG
Disease Info:
Drug: XL765 (SAR245409)
Drug Info: XL765 (SAR245409) is an oral dual inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) that was investigated in clinical trials for the treatment of advanced malignancies.
Effect: modulate
Effect Info: "XL765 can effectively inhibit the phosphorylation of AKT, p70S6K, and S6 in multiple tumor cell lines and suppress tumor growth."
Note:
Score: 4.0
Pubmed(PMID): 24634413
Sentence Index:
Sentence:

Sequence & Structure:

MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK

Select PDB:

Known Drugs:

source: Multi-Sources

(see table)

Target Drug name MOA Phase Status Disease Source
RPS6 ATALUREN 80S Ribosome modulator 4 - Duchenne muscular dystrophy EMA
RPS6 ATALUREN 80S Ribosome modulator 3 Completed Duchenne muscular dystrophy ClinicalTrials
ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Completed cystic fibrosis ClinicalTrials
ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Terminated cystic fibrosis ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Completed Becker muscular dystrophy ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Completed qualitative or quantitative defects of dystrophin ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Enrolling by invitation Duchenne muscular dystrophy ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 3 Terminated Duchenne muscular dystrophy ClinicalTrials
RPS6 MT-3724 80S Ribosome inhibitor 2 Terminated diffuse large B-cell lymphoma ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Completed epilepsy ClinicalTrials
RPS6 MT-3724 80S Ribosome inhibitor 2 Terminated non-Hodgkins lymphoma ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Terminated hemophilia A ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Completed Duchenne muscular dystrophy ClinicalTrials
ClinicalTrials
ClinicalTrials
ClinicalTrials
ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Terminated Duchenne muscular dystrophy ClinicalTrials
ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Completed cystic fibrosis ClinicalTrials
ClinicalTrials
ClinicalTrials
ClinicalTrials
RPS6 ELX-02 80S Ribosome modulator 2 Completed cystic fibrosis ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Terminated Becker muscular dystrophy ClinicalTrials
ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Completed Becker muscular dystrophy ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Terminated hemophilia B ClinicalTrials
RPS6 ELX-02 80S Ribosome modulator 2 Recruiting Alport syndrome ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Completed aniridia ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Withdrawn aniridia ClinicalTrials
RPS6 ELX-02 80S Ribosome modulator 2 Terminated cystinosis ClinicalTrials
RPS6 ATALUREN 80S Ribosome modulator 2 Terminated Disorder of amino acid and other organic acid metabolism ClinicalTrials
RPS6 MT-3724 80S Ribosome inhibitor 1 Terminated neoplasm of mature B-cells ClinicalTrials

Note: Only show clinically investigational or approved drugs with protein targets.

Protein Tractability:

source: Open Targets
Small molecule
Antibody
PROTAC
Other modalities
Approved Drug
Advanced Clinical
Phase 1 Clinical
Structure with Ligand
High-Quality Ligand
High-Quality Pocket
Med-Quality Pocket
Druggable Family
Approved Drug
Advanced Clinical
Phase 1 Clinical
UniProt loc high conf
GO CC high conf
UniProt loc med conf
UniProt SigP or TMHMM
GO CC med conf
Human Protein Atlas loc
Approved Drug
Advanced Clinical
Phase 1 Clinical
Literature
UniProt Ubiquitination
Database Ubiquitination
Half-life Data
Small Molecule Binder
Approved Drug
Advanced Clinical
Phase 1 Clinical

PTM Intensity:

source: CPTAC
RPS6-Ser240
Cancer Intensity
BRCA 1.329
COAD -0.99
HGSC 0.145
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC -0.484
UCEC

PTM-Disease Association:

source: PTMD
Residue Position State Disease Class PMID
S 240 U Tuberous sclerosis complex Phosphorylation 17671177
S 240 U Liver cancer Phosphorylation 23537100

State Note: Based on the distinct PTM states in diseases, PTMD classified all disease-associated PTMs into six classes, including whether the up-regulation (U) or down-regulation (D) of PTM levels, the absence (A) or presence (P) of PTMs, and the creation (C) or disruption (N) of PTM sites are associated with diseases.

PTM-Drug Perturbation Response:

source: DecryptM
Protein Gene PTM Position Modified sequence Cell Drug pEC50 Regulation Experiment
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK Ramos Rituximab -7.4771 up
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -3.8003 up
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -4.6934 up
P62753 RPS6 P Ser240;Ser242;Ser247 AS(ph)TS(ph)KSESS(ph)QK Ramos Rituximab -4.7156 up
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -2.2042 up
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -2.2138 up
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -2.7542 up
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -2.8265 up
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -2.8398 up
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 2 up
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Afatinib 6.5308 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 6.325 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 5.9116 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK A431 Dasatinib 5.9081 down
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 5.9051 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 5.7329 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A431 Dasatinib 5.6322 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Dasatinib 5.5489 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Dasatinib 5.2715 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A431 Dasatinib 5.1837 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 AZD8055 8.3597 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 AZD8055 8.0213 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A549 AZD8055 7.9584 down
P62753 RPS6 P Ser236;Ser240;Ser246 RLSS(ph)LRAS(ph)TSKSES(ph)SQK A549 AZD8055 7.9404 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 AZD8055 7.9324 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK A549 AZD8055 7.9217 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 AZD8055 7.9161 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 AZD8055 7.9141 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 AZD8055 7.89 down
P62753 RPS6 P Ser236;Ser240;Ser246 LSS(ph)LRAS(ph)TSKSES(ph)SQK A549 AZD8055 7.8724 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A549 Dactolisib 8.5491 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK A549 Dactolisib 8.4326 down
P62753 RPS6 P Ser235;Ser240;Thr241 RRLS(ph)SLRAS(ph)T(ph)SK A549 Dactolisib 8.2859 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Dactolisib 8.2365 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Dactolisib 8.0276 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 Dactolisib 8.0175 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Dactolisib 8.0083 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Dactolisib 7.9726 down
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Dactolisib 7.9619 down
P62753 RPS6 P Ser236;Ser240;Ser246 LSS(ph)LRAS(ph)TSKSES(ph)SQK A549 Dactolisib 7.9535 down
P62753 RPS6 P Ser235;Ser240;Ser246 RLS(ph)SLRAS(ph)TSKSES(ph)SQK A549 Dactolisib 7.953 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Dactolisib 7.9344 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Dactolisib 7.9101 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 7.5518 down
P62753 RPS6 P Ser235;Ser240;Thr241 RLS(ph)SLRAS(ph)T(ph)SKSESSQK A549 Dasatinib 5.1291 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 MK2206 5.0046 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 Nintedanib 5.3016 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Nintedanib 5.1438 down
P62753 RPS6 P Ser236;Ser240;Ser247 RLSS(ph)LRAS(ph)TSKSESS(ph)QK A549 Nintedanib 4.8527 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Pictilisib 7.1304 down
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Pictilisib 6.5208 down
P62753 RPS6 P Ser235;Ser240;Ser246 LS(ph)SLRAS(ph)TSKSES(ph)SQK A549 Pictilisib 6.5203 down
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Pictilisib 6.5009 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Pictilisib 6.4553 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Pictilisib 6.3551 down
P62753 RPS6 P Ser235;Ser240;Ser244 LS(ph)SLRAS(ph)TSKS(ph)ESSQK A549 Pictilisib 6.3499 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Pictilisib 6.3365 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Pictilisib 6.2881 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 Staursporin 8.0612 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Staursporin 8.0405 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK A549 Staursporin 7.932 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Staursporin 7.845 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A549 Staursporin 7.8301 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Staursporin 7.8238 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Staursporin 7.8024 down
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A549 Staursporin 7.7797 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Staursporin 7.7757 down
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Staursporin 7.6885 down
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Staursporin 7.3877 down
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 Staursporin 7.3144 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK ARH-77 Rituximab -1.3553 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -1.4309 down
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK ARH-77 Rituximab -0.6835 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK BT-474 Lapatinib 5.8713 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK HeLa Curcumin 4.103 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK MDA-MB-175 Lapatinib 6.6869 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK MDA-MB-175 Lapatinib 6.6525 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK MDA-MB-175 Lapatinib 6.6276 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK MDA-MB-175 Pertuzumab -4.5026 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK MDA-MB-175 Pertuzumab -4.5538 down
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK Ramos Rituximab -2.9871 down
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 8.7047 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 8.6859 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 8.6825 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 8.6181 down
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 8.5146 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 8.4941 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 8.4774 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 8.4568 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.4447 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.4361 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.3867 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 8.34 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.2704 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 8.2636 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.2388 down
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.0851 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 6.979 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK RPMI8226 BTZ 6.58 down
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK RPMI8226 BTZ 7.4041 down
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK RPMI8226 BTZ 6.0638 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 8.7098 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser247 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK RPMI8226 BTZ 8.6927 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.5201 down
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 8.3173 down
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 8.3073 down
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser247 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK RPMI8226 BTZ 8.0161 down
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 7.8181 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 7.8111 down
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 7.6649 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.783 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.6715 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 8.6374 down
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.4442 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.3388 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 8.2774 down
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SU-DHL-4 Rituximab -0.7677 down
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SU-DHL-4 Rituximab -1.782 down
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK MDA-MB-175 Trastuzumab -0.7334 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK MDA-MB-175 Trastuzumab -0.8034 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK MDA-MB-175 Trastuzumab -3.2796 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK PC-9 Gefitinib 8.386 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab 2.6344 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser247 LS(ph)SLRAS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -0.192 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK Ramos Rituximab -0.4434 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -0.4482 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -0.4576 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK Ramos Rituximab -0.4589 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK Ramos Rituximab -1.9813 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -3.2425 -
P62753 RPS6 P Ser240;Ser242;Ser247 AS(ph)TS(ph)KSESS(ph)QK Ramos Rituximab -3.2442 -
P62753 RPS6 P Ser240;Ser246;Ser247 AS(ph)TSKSES(ph)S(ph)QK Ramos Rituximab -3.2458 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -3.2494 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK Ramos Rituximab -4.2896 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -4.4559 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -6.2911 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK Ramos Rituximab -0.4813 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -1.4453 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -1.4673 -
P62753 RPS6 P Ser240;Ser242;Ser246 AS(ph)TS(ph)KSES(ph)SQK Ramos Rituximab -2.5595 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -2.7284 -
P62753 RPS6 P Ser240;Ser242;Ser247 AS(ph)TS(ph)KSESS(ph)QK Ramos Rituximab -2.7309 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -2.7325 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -2.924 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -1.3168 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -1.3373 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK Ramos Rituximab -1.3961 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -1.4271 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -1.4623 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK Ramos Rituximab -1.5227 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK Ramos Rituximab -1.6432 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK Ramos Rituximab -2.5241 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -2.6991 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -2.7135 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser246 LSS(ph)LRAS(ph)T(ph)SKSES(ph)SQK Ramos Rituximab -3.3993 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -3.4202 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser247 LSS(ph)LRAS(ph)TS(ph)KSESS(ph)QK Ramos Rituximab -3.4483 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK Ramos Rituximab -4.4161 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -3.1475 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -3.1658 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK Ramos Rituximab -1.0799 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK Ramos Rituximab -1.1815 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -1.3128 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser246 LSS(ph)LRAS(ph)T(ph)SKSES(ph)SQK Ramos Rituximab -1.3761 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK Ramos Rituximab -1.7088 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK Ramos Rituximab -1.7373 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK Ramos Rituximab -1.7426 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK Ramos Rituximab -1.7458 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK Ramos Rituximab -2.1024 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK Ramos Rituximab -3.5613 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 7.6108 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 7.573 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 12.7178 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 8.529 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 8.288 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 8.1285 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 7.8853 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 7.8781 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 7.8096 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 6.7094 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 6.7063 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 6.6398 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 6.6296 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 6.5035 -
P62753 RPS6 P Ser235;Ser236;Ser240 LS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 6.4987 -
P62753 RPS6 P Ser235;Ser236;Ser240 LS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 6.4811 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 6.2771 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 5.5193 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK RPMI8226 BTZ 7.8235 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK RPMI8226 BTZ 7.6638 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 7.409 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 7.3923 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 7.3223 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 7.2129 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 7.1683 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK RPMI8226 BTZ 7.1218 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK RPMI8226 BTZ 6.8929 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 5.8596 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK RPMI8226 BTZ 5.4651 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK RPMI8226 BTZ 5.1723 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 16 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK RPMI8226 BTZ 8.7767 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.3591 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 7.8993 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 7.8715 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 7.7275 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK RPMI8226 BTZ 7.4633 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.4951 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 8.4856 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK RPMI8226 BTZ 8.4534 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK RPMI8226 BTZ 8.3037 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK SK-BR-3 Lapatinib 8.5197 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK SK-BR-3 Lapatinib 8.444 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK SK-BR-3 Lapatinib 7.288 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SK-BR-3 Lapatinib 7.261 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK SK-BR-3 Lapatinib 7.2601 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK SK-BR-3 Pertuzumab 5 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK SK-BR-3 Pertuzumab 5 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK SK-BR-3 Pertuzumab 3.7577 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SK-BR-3 Pertuzumab -1.2352 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SK-BR-3 Pertuzumab -1.7407 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK SK-BR-3 Pertuzumab -1.7425 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK SK-BR-3 Pertuzumab -3.3741 -
P62753 RPS6 P Ser240 AS(ph)TSKSESSQK SK-BR-3 Pertuzumab -4.7409 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK SK-BR-3 Trastuzumab -1.0136 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK SK-BR-3 Trastuzumab -2.2084 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK SK-BR-3 Trastuzumab -2.5083 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SK-BR-3 Trastuzumab -2.7262 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SK-BR-3 Trastuzumab -3.8481 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SU-DHL-4 Rituximab -1.0803 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK SU-DHL-4 Rituximab -1.3352 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SU-DHL-4 Rituximab -1.3942 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK SU-DHL-4 Rituximab -1.5562 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SU-DHL-4 Rituximab 5.5229 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK SU-DHL-4 Rituximab -1.9889 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK SU-DHL-4 Rituximab -2.1034 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK SU-DHL-4 Rituximab -7.4771 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 14.17 -
P62753 RPS6 P Ser240;Ser244 AS(ph)TSKS(ph)ESSQK A431 Afatinib 8.7599 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK A431 Afatinib 8.7431 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Afatinib 7.8508 -
P62753 RPS6 P Ser236;Ser240;Ser246 LSS(ph)LRAS(ph)TSKSES(ph)SQK A431 Afatinib 7.1543 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser247 LSS(ph)LRAS(ph)TS(ph)KSESS(ph)QK A431 Afatinib 6.9828 -
P62753 RPS6 P Ser240;Thr241;Ser246 LSSLRAS(ph)T(ph)SKSES(ph)SQK A431 Afatinib 6.9177 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Afatinib 6.8489 -
P62753 RPS6 P Ser240;Ser244 LSSLRAS(ph)TSKS(ph)ESSQK A431 Afatinib 6.8128 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Afatinib 6.6329 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 6.5482 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK A431 Afatinib 3.5579 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Afatinib 9.2408 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Afatinib 8.3049 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 8.1313 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK A431 Afatinib 7.9872 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Afatinib 7.904 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 6.4034 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 6.2605 -
P62753 RPS6 P Ser240;Ser244 AS(ph)TSKS(ph)ESSQK A431 Afatinib 2 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 11.3378 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Afatinib 8.2889 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Afatinib 8.2793 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 8.271 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 8.2591 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser244;Ser247 LSS(ph)LRAS(ph)T(ph)SKS(ph)ESS(ph)QK A431 Afatinib 7.783 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Afatinib 7.581 -
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 7.1496 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 16.5229 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 16.5229 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK A431 Afatinib 16.5229 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 12.7667 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Afatinib 11.3475 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Afatinib 10.6082 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Afatinib 8.8673 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Afatinib 8.6608 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Afatinib 8.3866 -
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A431 Afatinib 7.7725 -
P62753 RPS6 P Ser235;Ser240;Thr241;Ser246 RLS(ph)SLRAS(ph)T(ph)SKSES(ph)SQK A431 Afatinib 7.6625 -
P62753 RPS6 P Ser240;Ser244 LSSLRAS(ph)TSKS(ph)ESSQK A431 Afatinib 7.6445 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK A431 Afatinib 7.2639 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser244;Ser246 RLSS(ph)LRAS(ph)T(ph)SKS(ph)ES(ph)SQK A431 Afatinib 2.1958 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 10.6914 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Dasatinib 9.1788 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Dasatinib 9.0468 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A431 Dasatinib 8.9679 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A431 Dasatinib 8.7536 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Dasatinib 7.7657 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 6.7511 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 6.5411 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser247 LSS(ph)LRAS(ph)TS(ph)KSESS(ph)QK A431 Dasatinib 6.2323 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A431 Dasatinib 5.7097 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 5.5937 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Dasatinib 5.4883 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 4.8888 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 4.8441 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 4.7228 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 7.8611 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 6.7833 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 6.7816 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Dasatinib 6.7683 -
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A431 Dasatinib 6.5341 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Dasatinib 5.5735 -
P62753 RPS6 P Ser235;Ser240;Ser242 LS(ph)SLRAS(ph)TS(ph)KSESSQK A431 Dasatinib 5.5139 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Dasatinib 4.7757 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Dasatinib 4.5165 -
P62753 RPS6 P Ser240;Ser247 AS(ph)TSKSESS(ph)QK A431 Dasatinib 10.6821 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK A431 Dasatinib 10.4592 -
P62753 RPS6 P Ser240;Ser242;Ser247 AS(ph)TS(ph)KSESS(ph)QK A431 Dasatinib 10.4261 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser244;Ser246 LSS(ph)LRAS(ph)T(ph)SKS(ph)ES(ph)SQK A431 Dasatinib 9.1126 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Dasatinib 8.9452 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 RLSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 8.93 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Dasatinib 8.8417 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 8.8115 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 8.7547 -
P62753 RPS6 P Ser240;Ser244 LSSLRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 8.7516 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Dasatinib 8.6613 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser244;Ser247 LSS(ph)LRAS(ph)TS(ph)KS(ph)ESS(ph)QK A431 Dasatinib 7.762 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 5.248 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK A431 Dasatinib 13.6805 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Dasatinib 12.1169 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser244;Ser246 RLSS(ph)LRAS(ph)T(ph)SKS(ph)ES(ph)SQK A431 Dasatinib 11.0371 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Dasatinib 10.899 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Dasatinib 10.7607 -
P62753 RPS6 P Ser240;Ser244 LSSLRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 8.4897 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Dasatinib 5.8318 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A431 Dasatinib 5.7551 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser244;Ser247 LSS(ph)LRAS(ph)T(ph)SKS(ph)ESS(ph)QK A431 Dasatinib 5.3773 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Dasatinib 2 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 8.1934 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 7.7144 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 7.0172 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 7.0074 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 6.9872 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 6.9665 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK A431 Gefitinib 6.8379 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Gefitinib 6.2082 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 4.8806 -
P62753 RPS6 P Ser240;Ser244;Ser246 AS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 10.4928 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 8.2569 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 RLSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 8.2519 -
P62753 RPS6 P Ser235;Ser240;Ser242;Ser247 LS(ph)SLRAS(ph)TS(ph)KSESS(ph)QK A431 Gefitinib 8.028 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 8.0232 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Gefitinib 7.9229 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Gefitinib 7.7579 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 7.2872 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Gefitinib 6.4267 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 6.4162 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 6.3613 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 6.2718 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK A431 Gefitinib 6.2706 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser244;Ser247 LSS(ph)LRAS(ph)TS(ph)KS(ph)ESS(ph)QK A431 Gefitinib 9.8244 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 9.2656 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 9.2613 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 9.2594 -
P62753 RPS6 P Ser240;Ser244 LSSLRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 9.2539 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK A431 Gefitinib 9.1682 -
P62753 RPS6 P Ser235;Ser240;Thr241;Ser246 RLS(ph)SLRAS(ph)T(ph)SKSES(ph)SQK A431 Gefitinib 9.0216 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Gefitinib 8.0045 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Gefitinib 6.8248 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 6.7892 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 5.3685 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 5.3659 -
P62753 RPS6 P Ser235;Ser240;Thr241 RLS(ph)SLRAS(ph)T(ph)SKSESSQK A431 Gefitinib 5.291 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 16.0229 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 8.7373 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 8.5104 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser247 LSS(ph)LRAS(ph)TS(ph)KSESS(ph)QK A431 Gefitinib 8.0807 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Gefitinib 7.8379 -
P62753 RPS6 P Ser235;Ser240;Ser242 LS(ph)SLRAS(ph)TS(ph)KSESSQK A431 Gefitinib 7.3703 -
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 7.0391 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A431 Gefitinib 7.003 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Gefitinib 6.325 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK A431 Gefitinib 6.2841 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Gefitinib 6.2472 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Gefitinib 6.2223 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A431 Gefitinib 6.1406 -
P62753 RPS6 P Ser236;Ser240;Ser246 RLSS(ph)LRAS(ph)TSKSES(ph)SQK A431 Imatinib 10.7671 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A431 Imatinib 10.1691 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK A431 Imatinib 9.0853 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser247 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK A431 Imatinib 8.9772 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A431 Imatinib 8.9211 -
P62753 RPS6 P Ser235;Ser240;Ser242 RRLS(ph)SLRAS(ph)TS(ph)K A431 Imatinib 8.1616 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK A431 Imatinib 8.0031 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A431 Imatinib 7.7438 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK A431 Imatinib 7.6636 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A431 Imatinib 7.3595 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A431 Imatinib 7.2899 -
P62753 RPS6 P Ser236;Ser240;Ser246 LSS(ph)LRAS(ph)TSKSES(ph)SQK A431 Imatinib 7.2769 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A431 Imatinib 7.0851 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK A431 Imatinib 6.9285 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A431 Imatinib 6.0402 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK A431 Imatinib 5.4144 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A431 Imatinib 5.2412 -
P62753 RPS6 P Ser235;Ser236;Ser240;Thr241 RLS(ph)S(ph)LRAS(ph)T(ph)SKSESSQK A431 Imatinib 3.0187 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser247 LSS(ph)LRAS(ph)TS(ph)KSESS(ph)QK A431 Imatinib 2.2055 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A459 MK2206 7.725 -
P62753 RPS6 P Ser240;Ser246;Ser247 LSSLRAS(ph)TSKSES(ph)S(ph)QK A549 AZD8055 15 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 AZD8055 9.7208 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 AZD8055 8.932 -
P62753 RPS6 P Ser240;Ser244;Ser246 RLSSLRAS(ph)TSKS(ph)ES(ph)SQK A549 AZD8055 8.0507 -
P62753 RPS6 P Ser240;Ser244;Ser247 LSSLRAS(ph)TSKS(ph)ESS(ph)QK A549 AZD8055 7.2506 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Dactolisib 8.7832 -
P62753 RPS6 P Ser240;Ser242;Ser247 LSSLRAS(ph)TS(ph)KSESS(ph)QK A549 Dactolisib 8.7592 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSKSESSQK A549 Dactolisib 6.4717 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 Dactolisib 4.2818 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 15 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 10.9173 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 10.7144 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A549 Dasatinib 10.5607 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Dasatinib 8.764 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 8.7358 -
P62753 RPS6 P Ser235;Ser240 RRLS(ph)SLRAS(ph)TSK A549 Dasatinib 8.6805 -
P62753 RPS6 P Ser235;Ser236;Ser240 LS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Dasatinib 8.5321 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A549 Dasatinib 8.2547 -
P62753 RPS6 P Ser235;Ser240;Thr241 LS(ph)SLRAS(ph)T(ph)SKSESSQK A549 Dasatinib 7.7513 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 Dasatinib 7.1403 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 Dasatinib 6.8855 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Dasatinib 6.8673 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Dasatinib 6.8288 -
P62753 RPS6 P Ser236;Ser240;Thr241 LSS(ph)LRAS(ph)T(ph)SKSESSQK A549 Dasatinib 6.2549 -
P62753 RPS6 P Ser236;Ser240;Ser246 RLSS(ph)LRAS(ph)TSKSES(ph)SQK A549 Dasatinib 6.2484 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 Dasatinib 6.2456 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Dasatinib 6.0321 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Dasatinib 5.7016 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Dasatinib 4.7038 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK A549 Dasatinib 4.3897 -
P62753 RPS6 P Ser235;Ser240;Ser244 RLS(ph)SLRAS(ph)TSKS(ph)ESSQK A549 Dasatinib 4.0161 -
P62753 RPS6 P Ser235;Ser240;Thr241 RRLS(ph)SLRAS(ph)T(ph)SK A549 Dasatinib 3.7543 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Dasatinib 2.2451 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Dasatinib 2.1856 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Dasatinib 2 -
P62753 RPS6 P Ser240;Ser244;Ser247 RLSSLRAS(ph)TSKS(ph)ESS(ph)QK A549 Dasatinib 2 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A549 Dasatinib 2 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 MK2206 8.0162 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 MK2206 7.9012 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 MK2206 7.8946 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 MK2206 7.458 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 MK2206 7.3826 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 MK2206 7.2789 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A549 MK2206 6.9915 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSKSESSQK A549 MK2206 6.8542 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 MK2206 6.3515 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Nintedanib 15 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK A549 Nintedanib 10.677 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Nintedanib 10.4815 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Nintedanib 8.3874 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Nintedanib 6.746 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Nintedanib 5.6498 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Nintedanib 5.3104 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Nintedanib 5.2578 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Nintedanib 4.9093 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 PD325901 15 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A549 PD325901 11.1332 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 PD325901 11.1098 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser246 LSS(ph)LRAS(ph)T(ph)SKSES(ph)SQK A549 PD325901 11.1089 -
P62753 RPS6 P Ser235;Ser240 RRLS(ph)SLRAS(ph)TSK A549 PD325901 11.0992 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 PD325901 11.0266 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246;Ser247 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK A549 PD325901 10.9207 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser242;Ser246 RLSS(ph)LRAS(ph)T(ph)S(ph)KSES(ph)SQK A549 PD325901 10.8288 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 PD325901 10.7412 -
P62753 RPS6 P Ser235;Ser240;Thr241;Ser244;Ser247 RLS(ph)SLRAS(ph)T(ph)SKS(ph)ESS(ph)QK A549 PD325901 10.7122 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSKSESSQK A549 PD325901 9.5528 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 PD325901 9.1593 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 PD325901 8.3259 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 PD325901 8.2373 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 PD325901 8.1532 -
P62753 RPS6 P Ser235;Ser240;Ser244 RLS(ph)SLRAS(ph)TSKS(ph)ESSQK A549 PD325901 8.0413 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 PD325901 8.0167 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 PD325901 7.2201 -
P62753 RPS6 P Ser236;Ser240;Ser246 RLSS(ph)LRAS(ph)TSKSES(ph)SQK A549 PD325901 6.9334 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 PD325901 6.6833 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 PD325901 5.8527 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK A549 PD325901 5.5426 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 PD325901 5.5262 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 PD325901 5.4874 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 PD325901 5.2671 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 PD325901 5.2179 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 PD325901 2 -
P62753 RPS6 P Ser240;Ser244;Ser246 LSSLRAS(ph)TSKS(ph)ES(ph)SQK A549 Pictilisib 7.7642 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Pictilisib 7.6584 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Refametinib 15 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Refametinib 10.9583 -
P62753 RPS6 P Ser235;Ser240 RRLS(ph)SLRAS(ph)TSK A549 Refametinib 9.9787 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK A549 Refametinib 9.5648 -
P62753 RPS6 P Ser236;Ser240;Thr241;Ser242;Ser246 RLSS(ph)LRAS(ph)T(ph)S(ph)KSES(ph)SQK A549 Refametinib 7.9601 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Refametinib 7.9175 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Refametinib 7.7586 -
P62753 RPS6 P Ser240 RLSSLRAS(ph)TSK A549 Refametinib 6.9136 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK A549 Refametinib 6.8448 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Refametinib 6.602 -
P62753 RPS6 P Ser235;Ser240;Ser242 LS(ph)SLRAS(ph)TS(ph)KSESSQK A549 Refametinib 6.5127 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246;Ser247 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK A549 Refametinib 6.3401 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK A549 Refametinib 6.201 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK A549 Refametinib 5.2547 -
P62753 RPS6 P Ser235;Ser240;Thr241 RRLS(ph)SLRAS(ph)T(ph)SK A549 Refametinib 5.241 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK A549 Tideglusib 11.091 -
P62753 RPS6 P Ser235;Ser240;Thr241;Ser242;Ser247 RLS(ph)SLRAS(ph)T(ph)S(ph)KSESS(ph)QK A549 Tideglusib 11.0855 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK A549 Tideglusib 11.0642 -
P62753 RPS6 P Ser235;Ser240;Ser242 LS(ph)SLRAS(ph)TS(ph)KSESSQK A549 Tideglusib 10.8554 -
P62753 RPS6 P Ser235;Ser240;Thr241 RRLS(ph)SLRAS(ph)T(ph)SK A549 Tideglusib 8.958 -
P62753 RPS6 P Ser236;Ser240;Thr241 RLSS(ph)LRAS(ph)T(ph)SKSESSQK A549 Tideglusib 8.8796 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK A549 Tideglusib 8.7798 -
P62753 RPS6 P Ser236;Ser240;Ser246 RLSS(ph)LRAS(ph)TSKSES(ph)SQK A549 Tideglusib 8.7792 -
P62753 RPS6 P Ser236;Ser240;Thr241 LSS(ph)LRAS(ph)T(ph)SKSESSQK A549 Tideglusib 8.77 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK A549 Tideglusib 8.756 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK A549 Tideglusib 8.6061 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK A549 Tideglusib 8.505 -
P62753 RPS6 P Ser240;Ser242 LSSLRAS(ph)TS(ph)KSESSQK A549 Tideglusib 7.9274 -
P62753 RPS6 P Ser240;Ser246;Ser247 LSSLRAS(ph)TSKSES(ph)S(ph)QK A549 Tideglusib 7.5849 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK A549 Tideglusib 7.5092 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK A549 Tideglusib 6.0736 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK A549 Tideglusib 6.0112 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK A549 Tideglusib 5.9538 -
P62753 RPS6 P Ser240;Ser244;Ser246 RLSSLRAS(ph)TSKS(ph)ES(ph)SQK A549 Tideglusib 5.7636 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK A549 Tideglusib 5.749 -
P62753 RPS6 P Ser235;Ser240;Ser244;Ser246;Ser247 RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK A549 Tideglusib 5.253 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser246 LSS(ph)LRAS(ph)TS(ph)KSES(ph)SQK A549 Tideglusib 5.2486 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK ARH-77 Rituximab 0.8863 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK ARH-77 Rituximab -1.0292 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK ARH-77 Rituximab -1.0334 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246;Ser247 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK ARH-77 Rituximab -1.2326 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -3.4401 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -4.2696 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK ARH-77 Rituximab 1.1756 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK ARH-77 Rituximab -3.7361 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK ARH-77 Rituximab -3.7468 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -3.8273 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -3.2148 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK ARH-77 Rituximab -3.2241 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK ARH-77 Rituximab -3.2249 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -2.9595 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK ARH-77 Rituximab 2.2176 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK ARH-77 Rituximab 0.7731 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK ARH-77 Rituximab -1.2602 -
P62753 RPS6 P Ser240;Ser244;Ser247 AS(ph)TSKS(ph)ESS(ph)QK ARH-77 Rituximab -4.2383 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK BT-474 Lapatinib 5.7548 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK BT-474 Lapatinib 5.7515 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK BT-474 Pertuzumab -3.7319 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK BT-474 Trastuzumab -1.6826 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK BT-474 Trastuzumab -1.7351 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK BT-474 Trastuzumab -2.0608 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK HeLa A485 6.3075 -
P62753 RPS6 P Ser235;Ser240 RRLS(ph)SLRAS(ph)TSK HeLa A485 6.2444 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK HeLa A485 5.3185 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK HeLa A485 5.2531 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK HeLa A485 1 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK HeLa A485 1 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK HeLa A486 10.1972 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK HeLa A486 5.7613 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK HeLa A486 5.0807 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK HeLa A486 5.0404 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK HeLa A486 4.6878 -
P62753 RPS6 P Ser235;Ser240 RRLS(ph)SLRAS(ph)TSK HeLa A486 4.2607 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK HeLa A486 1 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK HeLa CUDC101 6.6883 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSKSESSQK HeLa Curcumin 5.0223 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK HeLa SAHA 6.2455 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 14.868 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK K562 Dasatinib 13.3663 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 13.2447 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser244;Ser247 LSS(ph)LRAS(ph)TS(ph)KS(ph)ESS(ph)QK K562 Dasatinib 9.2751 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK K562 Dasatinib 9.2687 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK K562 Dasatinib 9.2632 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK K562 Dasatinib 9.2182 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK K562 Dasatinib 8.9658 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 8.6575 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 8.5713 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 8.5261 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 8.299 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK K562 Dasatinib 8.2779 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 8.2721 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 8.0193 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK K562 Dasatinib 8.0172 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 8.0142 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 8.0108 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 7.8945 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK K562 Dasatinib 7.8895 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK K562 Dasatinib 7.7812 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 7.755 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK K562 Dasatinib 7.6467 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSKSESSQK K562 Dasatinib 7.4774 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK K562 Dasatinib 6.9961 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK K562 Dasatinib 6.9079 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK K562 Dasatinib 6.8669 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 6.85 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK K562 Dasatinib 6.1358 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 5.6801 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK K562 Dasatinib 5.5901 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK K562 Dasatinib 5.3049 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242;Ser246 RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK K562 Dasatinib 4.1393 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 LSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK K562 Dasatinib 3.8811 -
P62753 RPS6 P Ser240;Thr241;Ser242 LSSLRAS(ph)T(ph)S(ph)KSESSQK K562 Dasatinib 2 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK K562 Dasatinib 9.3291 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser247 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK K562 Dasatinib 9.278 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 9.2519 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 9.1897 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK K562 Dasatinib 8.2774 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 7.6342 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK K562 Dasatinib 4 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK K562 Dasatinib 14.4785 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK K562 Dasatinib 9.7836 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK K562 Dasatinib 9.7498 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 9.7482 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK K562 Dasatinib 9.7346 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Dasatinib 9.7343 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSKSESSQK K562 Dasatinib 9.7342 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSK K562 Dasatinib 9.7184 -
P62753 RPS6 P Ser236;Ser240;Ser242 RLSS(ph)LRAS(ph)TS(ph)KSESSQK K562 Dasatinib 9.5362 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Dasatinib 8.9762 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK K562 Dasatinib 8.924 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK K562 Dasatinib 8.7694 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK K562 Imatinib 16.5229 -
P62753 RPS6 P Ser235;Ser236;Ser240 RRLS(ph)S(ph)LRAS(ph)TSK K562 Imatinib 12.0932 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSK K562 Imatinib 11.3803 -
P62753 RPS6 P Ser240;Ser246;Ser247 RLSSLRAS(ph)TSKSES(ph)S(ph)QK K562 Imatinib 9.9957 -
P62753 RPS6 P Ser236;Ser240;Ser244 LSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Imatinib 9.4662 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser247 LSS(ph)LRAS(ph)TSKS(ph)ESS(ph)QK K562 Imatinib 8.2736 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK K562 Imatinib 8.0309 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK K562 Imatinib 7.9784 -
P62753 RPS6 P Ser235;Ser240 LS(ph)SLRAS(ph)TSK K562 Imatinib 7.7588 -
P62753 RPS6 P Ser235;Ser240 RLS(ph)SLRAS(ph)TSK K562 Imatinib 7.2368 -
P62753 RPS6 P Ser236;Ser240 RLSS(ph)LRAS(ph)TSKSESSQK K562 Imatinib 7.235 -
P62753 RPS6 P Ser236;Ser240;Ser244 RLSS(ph)LRAS(ph)TSKS(ph)ESSQK K562 Imatinib 7.0556 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK K562 Imatinib 6.7357 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser242 RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK K562 Imatinib 6.6581 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser244;Ser246 RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK K562 Imatinib 6.6078 -
P62753 RPS6 P Ser236;Ser240;Ser242 LSS(ph)LRAS(ph)TS(ph)KSESSQK K562 Imatinib 6.4728 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSKSESSQK K562 Imatinib 6.4565 -
P62753 RPS6 P Ser235;Ser236;Ser240;Ser246 RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK K562 Imatinib 6.2913 -
P62753 RPS6 P Ser236;Ser240;Thr241 RLSS(ph)LRAS(ph)T(ph)SKSESSQK K562 Imatinib 6.266 -
P62753 RPS6 P Ser236;Ser240;Ser244;Ser246 RLSS(ph)LRAS(ph)TSKS(ph)ES(ph)SQK K562 Imatinib 5.7761 -
P62753 RPS6 P Ser236;Ser240;Ser242;Ser244;Ser247 LSS(ph)LRAS(ph)TS(ph)KS(ph)ESS(ph)QK K562 Imatinib 5.29 -
P62753 RPS6 P Ser235;Ser236;Ser240 RLS(ph)S(ph)LRAS(ph)TSK MDA-MB-175 Pertuzumab 2 -
P62753 RPS6 P Ser240 LSSLRAS(ph)TSK MDA-MB-175 Pertuzumab -4.2769 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK MDA-MB-175 Pertuzumab -4.5995 -
P62753 RPS6 P Ser236;Ser240 LSS(ph)LRAS(ph)TSKSESSQK MDA-MB-175 Trastuzumab 0.9894 -

pEC50 Note: pEC50 is the negative logarithm of EC50 (half-maximal effective concentration, dosage unit Mol), calculated as pEC50 = -log10(EC50), which quantifies the potency of a drug or compound.

Function score:

source: funscoR

No data.

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