PMADS

Id:	acc0746
Group:	2sens
Protein:	S6
Gene Symbol:	RPS6
Protein Id:	P62753
Protein Name:	RS6_HUMAN
PTM:	phosphorylation
Site:	Ser235
Site Sequence:	EQIAKRRRLSSLRASTSKSES
Disease Category:	Cancer
Disease:	Cholangiocarcinoma
Disease Subtype:
Disease Cellline:	QBC939
Disease Info:
Drug:	5-FU
Drug Info:	"5-FU (5-fluorouracil) is a chemotherapeutic antimetabolite that inhibits thymidylate synthase, thereby interfering with DNA synthesis and RNA function, and is primarily used in the treatment of colorectal, breast, gastric, and pancreatic cancers."
Effect:	inhibit
Effect Info:	"Capsaicin can effectively reverse the 5-FU-induced reduction of AKT and S6 phosphorylation, thereby inhibiting 5-FU-induced autophagy and enhancing the drug sensitivity of CCA cells to 5-FU."
Note:
Score:	5.0
Pubmed(PMID):	25933112
Sentence Index:	25933112_7-8
Sentence:	"Further investigation revealed that the autophagy induced by 5-FU was inhibited by capsaicin. Moreover, the decrease in AKT and S6 phosphorylation induced by 5-FU was effectively reversed by capsaicin, indicating that capsaicin inhibits 5-FU-induced autophagy by activating the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway in CCA cells."

Sequence & Structure:

MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK

Select PDB:

Known Drugs:

source: Multi-Sources

(see table)

Target	Drug name	MOA	Phase	Status	Disease	Source
RPS6	ATALUREN	80S Ribosome modulator	4	-	Duchenne muscular dystrophy	EMA
RPS6	ATALUREN	80S Ribosome modulator	3	Completed	Duchenne muscular dystrophy	ClinicalTrials ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Completed	cystic fibrosis	ClinicalTrials ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Terminated	cystic fibrosis	ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Completed	Becker muscular dystrophy	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Completed	qualitative or quantitative defects of dystrophin	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Enrolling by invitation	Duchenne muscular dystrophy	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	3	Terminated	Duchenne muscular dystrophy	ClinicalTrials
RPS6	MT-3724	80S Ribosome inhibitor	2	Terminated	diffuse large B-cell lymphoma	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Completed	epilepsy	ClinicalTrials
RPS6	MT-3724	80S Ribosome inhibitor	2	Terminated	non-Hodgkins lymphoma	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Terminated	hemophilia A	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Completed	Duchenne muscular dystrophy	ClinicalTrials ClinicalTrials ClinicalTrials ClinicalTrials ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Terminated	Duchenne muscular dystrophy	ClinicalTrials ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Completed	cystic fibrosis	ClinicalTrials ClinicalTrials ClinicalTrials ClinicalTrials
RPS6	ELX-02	80S Ribosome modulator	2	Completed	cystic fibrosis	ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Terminated	Becker muscular dystrophy	ClinicalTrials ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Completed	Becker muscular dystrophy	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Terminated	hemophilia B	ClinicalTrials
RPS6	ELX-02	80S Ribosome modulator	2	Recruiting	Alport syndrome	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Completed	aniridia	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Withdrawn	aniridia	ClinicalTrials
RPS6	ELX-02	80S Ribosome modulator	2	Terminated	cystinosis	ClinicalTrials
RPS6	ATALUREN	80S Ribosome modulator	2	Terminated	Disorder of amino acid and other organic acid metabolism	ClinicalTrials
RPS6	MT-3724	80S Ribosome inhibitor	1	Terminated	neoplasm of mature B-cells	ClinicalTrials

Note: Only show clinically investigational or approved drugs with protein targets.

Protein Tractability:

source: Open Targets

Small molecule

Antibody

PROTAC

Other modalities

Approved Drug

Advanced Clinical

Phase 1 Clinical

Structure with Ligand

High-Quality Ligand

High-Quality Pocket

Med-Quality Pocket

Druggable Family

Approved Drug

Advanced Clinical

Phase 1 Clinical

UniProt loc high conf

GO CC high conf

UniProt loc med conf

UniProt SigP or TMHMM

GO CC med conf

Human Protein Atlas loc

Approved Drug

Advanced Clinical

Phase 1 Clinical

Literature

UniProt Ubiquitination

Database Ubiquitination

Half-life Data

Small Molecule Binder

Approved Drug

Advanced Clinical

Phase 1 Clinical

PTM Intensity:

source: CPTAC

RPS6-Ser235
Cancer	Intensity
BRCA	1.184
COAD
HGSC
ccRCC	-0.383
GBM	0.073
HNSC	0.382
LUAD	0.449
LUSC	0.94
non_ccRCC	-2.268
PDAC	-0.16
UCEC	-0.215

PTM-Disease Association:

source: PTMD

Residue	Position	State	Disease	Class	PMID
S	235	D	Status epilepticus	Phosphorylation	32833881
S	235	D	Systemic lupus erythematosus	Phosphorylation	34522717
S	235	U	Kaposi's sarcoma	Phosphorylation	21819957
S	235	U	Non-small cell lung cancer	Phosphorylation	35596155

State Note: Based on the distinct PTM states in diseases, PTMD classified all disease-associated PTMs into six classes, including whether the up-regulation (U) or down-regulation (D) of PTM levels, the absence (A) or presence (P) of PTMs, and the creation (C) or disruption (N) of PTM sites are associated with diseases.

PTM-Drug Perturbation Response:

source: DecryptM

Protein	Gene	PTM	Position	Modified sequence	Cell	Drug	pEC50	Regulation
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Afatinib	6.7683	up
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Gefitinib	6.9723	up
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	AZD8055	7.9566	up
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Dactolisib	7.8829	up
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	MK2206	5.3874	up
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	HeLa	A485	4.763	up
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)K	Ramos	Rituximab	-2.7233	up
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-2.7542	up
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-2.8265	up
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Afatinib	6.5308	down
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser244;Ser247	RLS(ph)S(ph)LRAST(ph)SKS(ph)ESS(ph)QK	A431	Afatinib	6.327	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	A431	Afatinib	6.325	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Dasatinib	5.9561	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	5.9116	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	A431	Dasatinib	5.9081	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	5.9051	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Dasatinib	5.7936	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Dasatinib	5.7329	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Dasatinib	5.5489	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A431	Dasatinib	5.1837	down
P62753	RPS6	P	Ser235;Ser236;Ser244	RLS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	AZD8055	8.4856	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	AZD8055	8.3597	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	AZD8055	8.3213	down
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A549	AZD8055	8.0022	down
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A549	AZD8055	7.9746	down
P62753	RPS6	P	Ser235;Ser236;Ser244	LS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	AZD8055	7.971	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A549	AZD8055	7.9584	down
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	AZD8055	7.9262	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	A549	AZD8055	7.9217	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	AZD8055	7.9161	down
P62753	RPS6	P	Ser235;Ser242	LS(ph)SLRASTS(ph)KSESSQK	A549	AZD8055	7.8728	down
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)KSESSQK	A549	Dactolisib	8.8453	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A549	Dactolisib	8.5491	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	A549	Dactolisib	8.4326	down
P62753	RPS6	P	Ser235;Ser236;Ser244	RLS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	Dactolisib	8.4216	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Dactolisib	8.2895	down
P62753	RPS6	P	Ser235;Ser240;Thr241	RRLS(ph)SLRAS(ph)T(ph)SK	A549	Dactolisib	8.2859	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Dactolisib	8.2365	down
P62753	RPS6	P	Ser235;Ser236;Ser242	LS(ph)S(ph)LRASTS(ph)KSESSQK	A549	Dactolisib	8.0452	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	Dactolisib	8.0175	down
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SKSESSQK	A549	Dactolisib	7.989	down
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SKSESSQK	A549	Dactolisib	7.9817	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Dactolisib	7.9726	down
P62753	RPS6	P	Ser235;Ser240;Ser246	RLS(ph)SLRAS(ph)TSKSES(ph)SQK	A549	Dactolisib	7.953	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Dasatinib	7.5518	down
P62753	RPS6	P	Ser235;Ser236;Ser244	RLS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	Dasatinib	6.5971	down
P62753	RPS6	P	Ser235;Ser240;Thr241	RLS(ph)SLRAS(ph)T(ph)SKSESSQK	A549	Dasatinib	5.1291	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	MK2206	5.0046	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	Nintedanib	5.3016	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Nintedanib	5.2285	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Nintedanib	5.1438	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SKSESSQK	A549	Pictilisib	7.1752	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Pictilisib	7.1304	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Pictilisib	7.0306	down
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Pictilisib	6.8044	down
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SKSESSQK	A549	Pictilisib	6.534	down
P62753	RPS6	P	Ser235;Ser240;Ser246	LS(ph)SLRAS(ph)TSKSES(ph)SQK	A549	Pictilisib	6.5203	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Pictilisib	6.3551	down
P62753	RPS6	P	Ser235;Ser240;Ser244	LS(ph)SLRAS(ph)TSKS(ph)ESSQK	A549	Pictilisib	6.3499	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	Staursporin	8.0612	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Staursporin	8.0571	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Staursporin	8.0405	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SKSESSQK	A549	Staursporin	7.9977	down
P62753	RPS6	P	Ser235;Ser236;Ser242	LS(ph)S(ph)LRASTS(ph)KSESSQK	A549	Staursporin	7.9431	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	A549	Staursporin	7.932	down
P62753	RPS6	P	Ser235;Ser236;Thr241	LS(ph)S(ph)LRAST(ph)SKSESSQK	A549	Staursporin	7.9279	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A549	Staursporin	7.8301	down
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Staursporin	7.7972	down
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A549	Staursporin	7.7317	down
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Staursporin	7.6885	down
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Staursporin	7.2623	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-1.4309	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	ARH-77	Rituximab	-1.5913	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	BT-474	Lapatinib	5.8713	down
P62753	RPS6	P	Ser235;Ser236	LS(ph)S(ph)LRASTSKSESSQK	HeLa	Curcumin	4.1643	down
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSKSESSQK	HeLa	Curcumin	4.0316	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	MDA-MB-175	Lapatinib	6.9409	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	MDA-MB-175	Lapatinib	6.6276	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	MDA-MB-175	Pertuzumab	-4.5026	down
P62753	RPS6	P	Ser235;Ser236	LS(ph)S(ph)LRASTSKSESSQK	PC-9	AZD4547	7.9451	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	RPMI8226	BTZ	8.6859	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	RPMI8226	BTZ	8.6825	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	8.6181	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	RPMI8226	BTZ	8.4941	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	RPMI8226	BTZ	8.4774	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	8.4568	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.4447	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.4361	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	8.34	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	8.2636	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	RPMI8226	BTZ	6.979	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	RPMI8226	BTZ	6.58	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	8.7098	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser247	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK	RPMI8226	BTZ	8.6927	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.5201	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	RPMI8226	BTZ	8.4357	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser247	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK	RPMI8226	BTZ	8.0161	down
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	RPMI8226	BTZ	7.8489	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	7.8111	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.783	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	8.6374	down
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.4442	down
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	8.2774	down
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	A431	Afatinib	14.17	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Afatinib	7.7728	-
P62753	RPS6	P	Ser235;Ser236;Ser244;Ser246	RLS(ph)S(ph)LRASTSKS(ph)ES(ph)SQK	A431	Afatinib	7.5255	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Afatinib	6.8489	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Afatinib	6.6329	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Afatinib	6.5603	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	6.5482	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Afatinib	5.9933	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	A431	Afatinib	3.5579	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Afatinib	8.3049	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Afatinib	7.8453	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	6.4034	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Afatinib	6.266	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	6.2605	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	11.3378	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Afatinib	10.3828	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Afatinib	8.3009	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	A431	Afatinib	8.2889	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Afatinib	8.2793	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	A431	Afatinib	8.271	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	8.2591	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Afatinib	7.581	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Afatinib	7.4711	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Afatinib	6.5121	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	16.5229	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	A431	Afatinib	16.5229	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	A431	Afatinib	16.5229	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Afatinib	10.6082	-
P62753	RPS6	P	Ser235;Ser236;Ser242;Ser244	RLS(ph)S(ph)LRASTS(ph)KS(ph)ESSQK	A431	Afatinib	10.0658	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Afatinib	8.8673	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Afatinib	8.7565	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Afatinib	8.6608	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Afatinib	8.3866	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Afatinib	7.768	-
P62753	RPS6	P	Ser235;Ser240;Thr241;Ser246	RLS(ph)SLRAS(ph)T(ph)SKSES(ph)SQK	A431	Afatinib	7.6625	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK	A431	Afatinib	7.2639	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	10.6914	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Dasatinib	9.0242	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A431	Dasatinib	7.4799	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Dasatinib	7.4748	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Dasatinib	7.4596	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Dasatinib	6.7511	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A431	Dasatinib	6.0893	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A431	Dasatinib	5.8404	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A431	Dasatinib	5.7097	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Dasatinib	5.4883	-
P62753	RPS6	P	Ser235;Ser236;Ser244;Ser246	RLS(ph)S(ph)LRASTSKS(ph)ES(ph)SQK	A431	Dasatinib	5.4555	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Dasatinib	5.2906	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Dasatinib	4.8888	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Dasatinib	4.7228	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)KSESSQK	A431	Dasatinib	9.5195	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	7.8611	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Dasatinib	7.2641	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)K	A431	Dasatinib	6.9818	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Dasatinib	6.7833	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	6.7816	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Dasatinib	6.7736	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Dasatinib	6.7683	-
P62753	RPS6	P	Ser235;Ser236;Ser244;Ser246	RLS(ph)S(ph)LRASTSKS(ph)ES(ph)SQK	A431	Dasatinib	6.7571	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A431	Dasatinib	5.5843	-
P62753	RPS6	P	Ser235;Ser240;Ser242	LS(ph)SLRAS(ph)TS(ph)KSESSQK	A431	Dasatinib	5.5139	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Dasatinib	4.5165	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A431	Dasatinib	8.7374	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Dasatinib	7.7711	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	5.248	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Dasatinib	12.986	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Dasatinib	12.1169	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Dasatinib	10.899	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	A431	Dasatinib	10.7607	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser242;Ser246	RLS(ph)S(ph)LRAST(ph)S(ph)KSES(ph)SQK	A431	Dasatinib	10.6612	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Dasatinib	9.0351	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Dasatinib	5.4055	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A431	Gefitinib	7.412	-
P62753	RPS6	P	Ser235;Ser242	LS(ph)SLRASTS(ph)K	A431	Gefitinib	7.3962	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Gefitinib	7.0444	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	7.0172	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)K	A431	Gefitinib	7.0164	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser242;Ser246	RLS(ph)S(ph)LRAST(ph)S(ph)KSES(ph)SQK	A431	Gefitinib	7.0129	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Gefitinib	7.0074	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	6.9872	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	A431	Gefitinib	6.8379	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK	A431	Gefitinib	8.2569	-
P62753	RPS6	P	Ser235;Ser240;Ser242;Ser247	LS(ph)SLRAS(ph)TS(ph)KSESS(ph)QK	A431	Gefitinib	8.028	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Gefitinib	7.7803	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Gefitinib	7.7579	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	A431	Gefitinib	6.4267	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Gefitinib	6.4162	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Gefitinib	6.405	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Gefitinib	6.3613	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Gefitinib	6.3358	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	6.2718	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	A431	Gefitinib	6.2706	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Gefitinib	6.2698	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)K	A431	Gefitinib	9.2646	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	9.2613	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	A431	Gefitinib	9.1682	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A431	Gefitinib	9.0323	-
P62753	RPS6	P	Ser235;Ser240;Thr241;Ser246	RLS(ph)SLRAS(ph)T(ph)SKSES(ph)SQK	A431	Gefitinib	9.0216	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A431	Gefitinib	8.1662	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Gefitinib	5.4141	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	5.3685	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Gefitinib	5.3659	-
P62753	RPS6	P	Ser235;Ser240;Thr241	RLS(ph)SLRAS(ph)T(ph)SKSESSQK	A431	Gefitinib	5.291	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A431	Gefitinib	8.8034	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	8.7373	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Gefitinib	8.5342	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK	A431	Gefitinib	8.5104	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A431	Gefitinib	7.4277	-
P62753	RPS6	P	Ser235;Ser240;Ser242	LS(ph)SLRAS(ph)TS(ph)KSESSQK	A431	Gefitinib	7.3703	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A431	Gefitinib	7.003	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Gefitinib	6.325	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	A431	Gefitinib	6.2841	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Gefitinib	6.2472	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Gefitinib	6.2302	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	A431	Gefitinib	6.2223	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A431	Gefitinib	6.1406	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser244;Ser247	RLS(ph)S(ph)LRAST(ph)SKS(ph)ESS(ph)QK	A431	Imatinib	10.3435	-
P62753	RPS6	P	Ser235;Ser236;Ser242;Ser246	RLS(ph)S(ph)LRASTS(ph)KSES(ph)SQK	A431	Imatinib	10.2694	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A431	Imatinib	10.1691	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	A431	Imatinib	9.5974	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A431	Imatinib	9.2615	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK	A431	Imatinib	9.0853	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser247	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESS(ph)QK	A431	Imatinib	8.9772	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A431	Imatinib	8.9211	-
P62753	RPS6	P	Ser235;Ser240;Ser242	RRLS(ph)SLRAS(ph)TS(ph)K	A431	Imatinib	8.1616	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	A431	Imatinib	8.0031	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A431	Imatinib	7.932	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A431	Imatinib	7.2899	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	A431	Imatinib	6.9285	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Thr241	RLS(ph)S(ph)LRAS(ph)T(ph)SKSESSQK	A431	Imatinib	3.0187	-
P62753	RPS6	P	Ser235	LS(ph)SLRASTSK	A549	AZD8055	5.2456	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Dactolisib	8.1071	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A549	Dasatinib	10.5607	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SKSESSQK	A549	Dasatinib	9.607	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Dasatinib	8.764	-
P62753	RPS6	P	Ser235;Ser240	RRLS(ph)SLRAS(ph)TSK	A549	Dasatinib	8.6805	-
P62753	RPS6	P	Ser235;Ser236;Ser240	LS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Dasatinib	8.5321	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Dasatinib	8.4885	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SK	A549	Dasatinib	8.2581	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Dasatinib	7.8561	-
P62753	RPS6	P	Ser235;Ser240;Thr241	LS(ph)SLRAS(ph)T(ph)SKSESSQK	A549	Dasatinib	7.7513	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	A549	Dasatinib	7.3514	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	Dasatinib	7.1403	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	Dasatinib	6.8855	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Dasatinib	6.7331	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A549	Dasatinib	5.257	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	A549	Dasatinib	4.3897	-
P62753	RPS6	P	Ser235;Ser240;Ser244	RLS(ph)SLRAS(ph)TSKS(ph)ESSQK	A549	Dasatinib	4.0161	-
P62753	RPS6	P	Ser235;Ser240;Thr241	RRLS(ph)SLRAS(ph)T(ph)SK	A549	Dasatinib	3.7543	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Dasatinib	3.6991	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Dasatinib	2.2451	-
P62753	RPS6	P	Ser235;Ser236;Ser244	LS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	Dasatinib	2	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)KSESSQK	A549	Dasatinib	2	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	MK2206	7.8946	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SK	A549	MK2206	7.304	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A549	MK2206	6.9915	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	MK2206	6.7685	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	A549	Nintedanib	10.677	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Nintedanib	10.4815	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Nintedanib	6.734	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Nintedanib	5.8076	-
P62753	RPS6	P	Ser235;Ser236;Ser244;Ser246	RLS(ph)S(ph)LRASTSKS(ph)ES(ph)SQK	A549	Nintedanib	5.6771	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	A549	PD325901	15	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	PD325901	11.1098	-
P62753	RPS6	P	Ser235;Ser240	RRLS(ph)SLRAS(ph)TSK	A549	PD325901	11.0992	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	PD325901	11.0266	-
P62753	RPS6	P	Ser235;Ser236;Ser242	LS(ph)S(ph)LRASTS(ph)KSESSQK	A549	PD325901	10.9702	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246;Ser247	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK	A549	PD325901	10.9207	-
P62753	RPS6	P	Ser235;Ser240;Thr241;Ser244;Ser247	RLS(ph)SLRAS(ph)T(ph)SKS(ph)ESS(ph)QK	A549	PD325901	10.7122	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	PD325901	9.1593	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	PD325901	8.5488	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	PD325901	8.3259	-
P62753	RPS6	P	Ser235;Ser240;Ser244	RLS(ph)SLRAS(ph)TSKS(ph)ESSQK	A549	PD325901	8.0413	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	PD325901	7.7541	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	PD325901	7.5127	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	PD325901	6.6833	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	A549	PD325901	5.5426	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SK	A549	PD325901	5.2567	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	PD325901	5.2179	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	A549	Refametinib	15	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Refametinib	10.5424	-
P62753	RPS6	P	Ser235;Ser240	RRLS(ph)SLRAS(ph)TSK	A549	Refametinib	9.9787	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	A549	Refametinib	9.5648	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Refametinib	7.7586	-
P62753	RPS6	P	Ser235;Ser236;Ser242	LS(ph)S(ph)LRASTS(ph)KSESSQK	A549	Refametinib	7.5164	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Refametinib	7.4081	-
P62753	RPS6	P	Ser235;Ser240;Ser242	LS(ph)SLRAS(ph)TS(ph)KSESSQK	A549	Refametinib	6.5127	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246;Ser247	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK	A549	Refametinib	6.3401	-
P62753	RPS6	P	Ser235;Ser236;Ser244	LS(ph)S(ph)LRASTSKS(ph)ESSQK	A549	Refametinib	5.7766	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	A549	Refametinib	5.2547	-
P62753	RPS6	P	Ser235;Ser240;Thr241	RRLS(ph)SLRAS(ph)T(ph)SK	A549	Refametinib	5.241	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	A549	Tideglusib	11.091	-
P62753	RPS6	P	Ser235;Ser240;Thr241;Ser242;Ser247	RLS(ph)SLRAS(ph)T(ph)S(ph)KSESS(ph)QK	A549	Tideglusib	11.0855	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	A549	Tideglusib	11.0642	-
P62753	RPS6	P	Ser235;Ser240;Ser242	LS(ph)SLRAS(ph)TS(ph)KSESSQK	A549	Tideglusib	10.8554	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SKSESSQK	A549	Tideglusib	10.8	-
P62753	RPS6	P	Ser235	RRLS(ph)SLR	A549	Tideglusib	10.1936	-
P62753	RPS6	P	Ser235;Ser240;Thr241	RRLS(ph)SLRAS(ph)T(ph)SK	A549	Tideglusib	8.958	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	A549	Tideglusib	8.9429	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	A549	Tideglusib	8.8026	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	A549	Tideglusib	8.6061	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	A549	Tideglusib	7.5092	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	A549	Tideglusib	6.0736	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)SQK	A549	Tideglusib	5.749	-
P62753	RPS6	P	Ser235;Ser236;Thr241	LS(ph)S(ph)LRAST(ph)SKSESSQK	A549	Tideglusib	5.745	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser246;Ser247	RLS(ph)SLRAS(ph)TSKS(ph)ES(ph)S(ph)QK	A549	Tideglusib	5.253	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	ARH-77	Rituximab	5.5229	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	ARH-77	Rituximab	-1.0334	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	ARH-77	Rituximab	-1.2326	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	ARH-77	Rituximab	-3.2073	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-3.4401	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-4.2696	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	ARH-77	Rituximab	1.36	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	ARH-77	Rituximab	-3.7468	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	ARH-77	Rituximab	-3.7472	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-3.8273	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-3.2148	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	ARH-77	Rituximab	-3.2249	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-2.9595	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SK	ARH-77	Rituximab	0.8396	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	ARH-77	Rituximab	0.7731	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	ARH-77	Rituximab	-1.2602	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	ARH-77	Rituximab	-1.2625	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)K	ARH-77	Rituximab	-1.2642	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	BT-474	Lapatinib	5.7548	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	BT-474	Pertuzumab	-4.8414	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	BT-474	Trastuzumab	-1.6826	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	BT-474	Trastuzumab	-2.0608	-
P62753	RPS6	P	Ser235;Ser240	RRLS(ph)SLRAS(ph)TSK	HeLa	A485	6.2444	-
P62753	RPS6	P	Ser235	RLS(ph)SLRASTSK	HeLa	A485	6.1323	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SKSESSQK	HeLa	A485	5.8304	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	HeLa	A485	5.2531	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	HeLa	A485	1	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	HeLa	A486	10.2354	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	HeLa	A486	5.7613	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	HeLa	A486	5.0404	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	HeLa	A486	4.4636	-
P62753	RPS6	P	Ser235;Ser240	RRLS(ph)SLRAS(ph)TSK	HeLa	A486	4.2607	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	HeLa	A486	3.6788	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	HeLa	A486	1	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	HeLa	CUDC101	6.6883	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	K562	Dasatinib	13.3663	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	K562	Dasatinib	12.6329	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	K562	Dasatinib	10.2723	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	K562	Dasatinib	10.2689	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	K562	Dasatinib	9.2632	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	K562	Dasatinib	8.6575	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	8.5713	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	8.299	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	K562	Dasatinib	8.2779	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	8.2721	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	K562	Dasatinib	8.0172	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	K562	Dasatinib	8.0142	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	K562	Dasatinib	7.8945	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	K562	Dasatinib	7.8895	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SKSESSQK	K562	Dasatinib	7.7603	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	K562	Dasatinib	7.6467	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSKSESSQK	K562	Dasatinib	7.4774	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	K562	Dasatinib	7.3176	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	K562	Dasatinib	6.9079	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	6.85	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser244;Ser246	RLS(ph)S(ph)LRAST(ph)SKS(ph)ES(ph)SQK	K562	Dasatinib	6.8092	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser244;Ser247	RLS(ph)S(ph)LRAST(ph)SKS(ph)ESS(ph)QK	K562	Dasatinib	6.5772	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	K562	Dasatinib	6.3088	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	K562	Dasatinib	6.1358	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242;Ser246	RLS(ph)S(ph)LRAS(ph)TS(ph)KSES(ph)SQK	K562	Dasatinib	4.1393	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	K562	Dasatinib	2	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser247	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESS(ph)QK	K562	Dasatinib	9.278	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	9.1897	-
P62753	RPS6	P	Ser235;Ser236	RLS(ph)S(ph)LRASTSK	K562	Dasatinib	9.0392	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	K562	Dasatinib	8.2774	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SKSESSQK	K562	Dasatinib	7.3971	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SK	K562	Dasatinib	7.2781	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	K562	Dasatinib	14.4785	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	K562	Dasatinib	9.7836	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	K562	Dasatinib	9.7498	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	K562	Dasatinib	9.7346	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSKSESSQK	K562	Dasatinib	9.7342	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	K562	Dasatinib	8.7694	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	K562	Dasatinib	8.2728	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	K562	Dasatinib	7.2613	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	K562	Imatinib	16.5229	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	K562	Imatinib	12.0932	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	K562	Imatinib	8.0836	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	K562	Imatinib	7.7588	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	K562	Imatinib	7.2368	-
P62753	RPS6	P	Ser235;Ser236	RRLS(ph)S(ph)LR	K562	Imatinib	6.8892	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	K562	Imatinib	6.7357	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	K562	Imatinib	6.6581	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser244;Ser247	RLS(ph)S(ph)LRAST(ph)SKS(ph)ESS(ph)QK	K562	Imatinib	6.6426	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	K562	Imatinib	6.6078	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	K562	Imatinib	6.4565	-
P62753	RPS6	P	Ser235;Thr241	LS(ph)SLRAST(ph)SKSESSQK	K562	Imatinib	6.3121	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)SQK	K562	Imatinib	6.2913	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	MDA-MB-175	Pertuzumab	2	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	MDA-MB-175	Pertuzumab	2	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	MDA-MB-175	Trastuzumab	-0.7334	-
P62753	RPS6	P	Ser235;Ser236;Ser244	RLS(ph)S(ph)LRASTSKS(ph)ESSQK	MDA-MB-175	Trastuzumab	-3.2511	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	MDA-MB-175	Trastuzumab	-3.2796	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	2.6344	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	Ramos	Rituximab	2.1026	-
P62753	RPS6	P	Ser235;Ser240;Ser244;Ser247	LS(ph)SLRAS(ph)TSKS(ph)ESS(ph)QK	Ramos	Rituximab	-0.192	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-0.4482	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-0.4576	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-4.2896	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-1.4453	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-2.924	-
P62753	RPS6	P	Ser235;Ser236;Ser242	RLS(ph)S(ph)LRASTS(ph)KSESSQK	Ramos	Rituximab	-1.2617	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	Ramos	Rituximab	-1.2829	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-1.3168	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-1.3373	-
P62753	RPS6	P	Ser235;Ser242	RLS(ph)SLRASTS(ph)K	Ramos	Rituximab	-1.4015	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-1.4623	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	Ramos	Rituximab	-2.5241	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	Ramos	Rituximab	-3.4202	-
P62753	RPS6	P	Ser235;Ser236;Thr241;Ser242;Ser246	RLS(ph)S(ph)LRAST(ph)S(ph)KSES(ph)SQK	Ramos	Rituximab	-3.4671	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-3.1658	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-1.3128	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RRLS(ph)S(ph)LRAST(ph)SK	Ramos	Rituximab	-1.3539	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	Ramos	Rituximab	-1.7088	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	Ramos	Rituximab	-1.7411	-
P62753	RPS6	P	Ser235;Ser240	RLS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-1.7426	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	Ramos	Rituximab	-1.7458	-
P62753	RPS6	P	Ser235;Thr241	RLS(ph)SLRAST(ph)SK	Ramos	Rituximab	-1.7646	-
P62753	RPS6	P	Ser235	LS(ph)SLRASTSK	RPMI8226	BTZ	12.4397	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	8.288	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	7.8853	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	7.8781	-
P62753	RPS6	P	Ser235	LS(ph)SLRASTSK	RPMI8226	BTZ	7.8671	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	RPMI8226	BTZ	7.8	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	6.7094	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	6.6398	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	6.6296	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	RPMI8226	BTZ	6.5657	-
P62753	RPS6	P	Ser235;Ser236;Ser240	LS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	6.4987	-
P62753	RPS6	P	Ser235;Ser236;Ser240	LS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	6.4811	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	RPMI8226	BTZ	7.8235	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	RPMI8226	BTZ	7.6638	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	7.3923	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	RPMI8226	BTZ	7.3223	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	7.2129	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	7.1683	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser246;Ser247	RLS(ph)S(ph)LRAS(ph)TSKSES(ph)S(ph)QK	RPMI8226	BTZ	7.1218	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244;Ser246	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ES(ph)SQK	RPMI8226	BTZ	6.8929	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	RPMI8226	BTZ	5.4651	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser242	RLS(ph)S(ph)LRAS(ph)TS(ph)KSESSQK	RPMI8226	BTZ	5.1723	-
P62753	RPS6	P	Ser235;Ser236;Ser240;Ser244	RLS(ph)S(ph)LRAS(ph)TSKS(ph)ESSQK	RPMI8226	BTZ	8.7767	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.3591	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	7.8993	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.4951	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RRLS(ph)S(ph)LRAS(ph)TSK	RPMI8226	BTZ	8.4534	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	SK-BR-3	Lapatinib	8.444	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	SK-BR-3	Lapatinib	7.288	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	SK-BR-3	Lapatinib	7.2794	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	SK-BR-3	Lapatinib	7.2601	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSKSESSQK	SK-BR-3	Pertuzumab	5	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	SK-BR-3	Pertuzumab	-1.7425	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	SK-BR-3	Pertuzumab	-3.3638	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	SK-BR-3	Pertuzumab	-3.3741	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	SK-BR-3	Trastuzumab	-1.0136	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	SK-BR-3	Trastuzumab	-2.5083	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	SU-DHL-4	Rituximab	-1.2366	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	SU-DHL-4	Rituximab	-1.3352	-
P62753	RPS6	P	Ser235;Ser240	LS(ph)SLRAS(ph)TSK	SU-DHL-4	Rituximab	-1.5562	-
P62753	RPS6	P	Ser235;Ser236;Thr241	RLS(ph)S(ph)LRAST(ph)SK	SU-DHL-4	Rituximab	-1.9562	-
P62753	RPS6	P	Ser235;Ser236;Ser240	RLS(ph)S(ph)LRAS(ph)TSK	SU-DHL-4	Rituximab	-1.9889	-

pEC50 Note: pEC50 is the negative logarithm of EC50 (half-maximal effective concentration, dosage unit Mol), calculated as pEC50 = -log10(EC50), which quantifies the potency of a drug or compound.

Function score:

source: funscoR

No data.

Cross Links:

CTD
DMRdb