Id: acc2146
Group: 2sens
Protein: p53
Gene Symbol: TP53
Protein Id: P04637
Protein Name: P53_HUMAN
PTM: phosphorylation
Site: Ser15
Site Sequence: SDPSVEPPLSQETFSDLWKLL
Disease Category: Cancer
Disease: Colorectal Cancer
Disease Subtype:
Disease Cellline: HCT116
Disease Info:
Drug: NO + ionizing radiation
Drug Info: NO: - Ionizing radiation refers to radiation composed of particles or electromagnetic waves with sufficient energy to ionize atoms or molecules by detaching electrons from them.
Effect: enhance
Effect Info: NO and ionizing radiation significantly enhance p53-dependent apoptosis by increasing the phosphorylation of p53 at serine 15.
Note: Non-conventional drugs
Score: 4.5
Pubmed(PMID): 15520210
Sentence Index:
Sentence:

Sequence & Structure:

MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD

Select PDB:

Known Drugs:

source: Multi-Sources

(see table)

Target Drug name MOA Phase Status Disease Source
TP53 EPRENETAPOPT Cellular tumor antigen p53 stabiliser 3 Completed myelodysplastic syndrome ClinicalTrials
TP53 IDASANUTLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 3 Terminated acute myeloid leukemia ClinicalTrials
TP53 CENERSEN SODIUM p53 mRNA antisense inhibitor 2 Terminated chronic lymphocytic leukemia ClinicalTrials
TP53 CENERSEN p53 mRNA antisense inhibitor 2 Completed acute myeloid leukemia ClinicalTrials
TP53 CENERSEN p53 mRNA antisense inhibitor 2 Withdrawn acute myeloid leukemia ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting essential thrombocythemia ClinicalTrials
TP53 SIREMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting neoplasm ClinicalTrials
TP53 IDASANUTLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting neoplasm ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Terminated small cell lung carcinoma ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Active, not recruiting polycythemia vera ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting polycythemia vera ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting primary myelofibrosis ClinicalTrials
TP53 IDASANUTLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Terminated polycythemia vera ClinicalTrials
TP53 CONTUSUGENE LADENOVEC Cellular tumor antigen p53 exogenous gene 2 Unknown status non-small cell lung carcinoma ClinicalTrials
TP53 APG115 Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting lymphoid leukemia ClinicalTrials
TP53 CONTUSUGENE LADENOVEC Cellular tumor antigen p53 exogenous gene 2 Terminated head and neck malignant neoplasia ClinicalTrials
TP53 CONTUSUGENE LADENOVEC Cellular tumor antigen p53 exogenous gene 2 Unknown status head and neck malignant neoplasia ClinicalTrials
ClinicalTrials
TP53 EPRENETAPOPT Cellular tumor antigen p53 stabiliser 2 Withdrawn Mantle cell lymphoma ClinicalTrials
TP53 TEPRASIRAN p53 mRNA RNAi inhibitor 2 Completed Acute kidney injury ClinicalTrials
TP53 EPRENETAPOPT Cellular tumor antigen p53 stabiliser 2 Completed ovarian cancer ClinicalTrials
TP53 CONTUSUGENE LADENOVEC Cellular tumor antigen p53 exogenous gene 2 Completed breast cancer ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 2 Recruiting endometrial cancer ClinicalTrials
TP53 CENERSEN p53 mRNA antisense inhibitor 1 Terminated myelodysplastic syndrome ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 1 Active, not recruiting acute myeloid leukemia ClinicalTrials
ClinicalTrials
TP53 NAVTEMADLIN Tumour suppressor p53/oncoprotein Mdm2 inhibitor 1 Completed acute myeloid leukemia ClinicalTrials

Note: Only show clinically investigational or approved drugs with protein targets.

Protein Tractability:

source: Open Targets
Small molecule
Antibody
PROTAC
Other modalities
Approved Drug
Advanced Clinical
Phase 1 Clinical
Structure with Ligand
High-Quality Ligand
High-Quality Pocket
Med-Quality Pocket
Druggable Family
Approved Drug
Advanced Clinical
Phase 1 Clinical
UniProt loc high conf
GO CC high conf
UniProt loc med conf
UniProt SigP or TMHMM
GO CC med conf
Human Protein Atlas loc
Approved Drug
Advanced Clinical
Phase 1 Clinical
Literature
UniProt Ubiquitination
Database Ubiquitination
Half-life Data
Small Molecule Binder
Approved Drug
Advanced Clinical
Phase 1 Clinical

PTM Intensity:

source: CPTAC

No intensity data of this site,
show all other sites!

TP53-Ser314
Cancer Intensity
BRCA
COAD 0.707
HGSC
ccRCC
GBM
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53-Ser315
Cancer Intensity
BRCA
COAD -1.105
HGSC 0.842
ccRCC 0.263
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53-Thr150
Cancer Intensity
BRCA
COAD
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser101
Cancer Intensity
BRCA
COAD 0.422
HGSC -1.142
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.72
TP53BP1-Ser1024
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 0.707
GBM
HNSC
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1030
Cancer Intensity
BRCA
COAD -1.646
HGSC
ccRCC 0.325
GBM 1.443
HNSC -0.173
LUAD 0.213
LUSC
non_ccRCC
PDAC
UCEC -0.162
TP53BP1-Ser1033
Cancer Intensity
BRCA 1.211
COAD -0.937
HGSC 2.312
ccRCC -0.583
GBM -0.187
HNSC -0.362
LUAD -0.923
LUSC -0.762
non_ccRCC 0.539
PDAC -0.285
UCEC -0.023
TP53BP1-Ser1039
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC
LUAD
LUSC 0.707
non_ccRCC
PDAC
UCEC -0.707
TP53BP1-Ser1072
Cancer Intensity
BRCA
COAD -0.707
HGSC 1.378
ccRCC 0.381
GBM 0.572
HNSC -1.199
LUAD -1.107
LUSC
non_ccRCC
PDAC
UCEC 0.682
TP53BP1-Ser1073
Cancer Intensity
BRCA 0.669
COAD -1.359
HGSC 1.711
ccRCC 0.013
GBM -1.1
HNSC -0.352
LUAD -0.325
LUSC -0.93
non_ccRCC 1.416
PDAC 0.594
UCEC -0.338
TP53BP1-Ser108
Cancer Intensity
BRCA
COAD
HGSC -1.494
ccRCC 0.385
GBM
HNSC 0.592
LUAD 0.518
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1091
Cancer Intensity
BRCA -0.162
COAD
HGSC
ccRCC 0.068
GBM
HNSC -0.502
LUAD -1.047
LUSC
non_ccRCC 1.887
PDAC
UCEC -0.245
TP53BP1-Ser1099
Cancer Intensity
BRCA -0.026
COAD -0.791
HGSC 2.796
ccRCC -0.009
GBM -0.536
HNSC -0.528
LUAD -0.656
LUSC -0.569
non_ccRCC 0.469
PDAC -0.136
UCEC -0.016
TP53BP1-Ser110
Cancer Intensity
BRCA 1.172
COAD
HGSC -1.547
ccRCC
GBM
HNSC
LUAD -0.219
LUSC 0.235
non_ccRCC
PDAC
UCEC 0.359
TP53BP1-Ser1106
Cancer Intensity
BRCA -0.4
COAD -1.116
HGSC -0.312
ccRCC 0.547
GBM -0.568
HNSC -0.441
LUAD -0.968
LUSC -0.471
non_ccRCC 2.364
PDAC 0.704
UCEC 0.661
TP53BP1-Ser1109
Cancer Intensity
BRCA
COAD 0.039
HGSC -2.593
ccRCC 0.274
GBM 0.059
HNSC 0.319
LUAD
LUSC 0.217
non_ccRCC 0.798
PDAC 0.535
UCEC 0.352
TP53BP1-Ser1118
Cancer Intensity
BRCA
COAD -0.141
HGSC -1.543
ccRCC -1.102
GBM 0.247
HNSC 1.264
LUAD -0.614
LUSC 0.464
non_ccRCC -0.502
PDAC 1.68
UCEC 0.245
TP53BP1-Ser1119
Cancer Intensity
BRCA
COAD -0.086
HGSC -2.266
ccRCC 0.103
GBM 0.966
HNSC 0.693
LUAD 0.411
LUSC
non_ccRCC
PDAC -0.265
UCEC 0.442
TP53BP1-Ser1221
Cancer Intensity
BRCA
COAD 0.707
HGSC
ccRCC
GBM
HNSC
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1224
Cancer Intensity
BRCA
COAD 0.707
HGSC
ccRCC
GBM
HNSC
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser124
Cancer Intensity
BRCA
COAD 0.494
HGSC -1.151
ccRCC
GBM
HNSC
LUAD 0.657
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1293
Cancer Intensity
BRCA
COAD -1.016
HGSC 1.342
ccRCC
GBM 0.076
HNSC -0.402
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1295
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.707
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1300
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.707
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1301
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.707
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser132
Cancer Intensity
BRCA 0.744
COAD
HGSC
ccRCC
GBM
HNSC
LUAD -1.235
LUSC 0.878
non_ccRCC
PDAC
UCEC -0.387
TP53BP1-Ser1322
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1325
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1327
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1347
Cancer Intensity
BRCA
COAD
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.707
TP53BP1-Ser1367
Cancer Intensity
BRCA
COAD -0.307
HGSC 1.914
ccRCC -0.145
GBM
HNSC -0.147
LUAD -1.067
LUSC
non_ccRCC
PDAC -0.247
UCEC
TP53BP1-Ser1431
Cancer Intensity
BRCA 0.246
COAD 0.043
HGSC -2.497
ccRCC 0.213
GBM 0.159
HNSC -0.014
LUAD -0.134
LUSC -0.797
non_ccRCC 1.417
PDAC 0.55
UCEC 0.816
TP53BP1-Ser1435
Cancer Intensity
BRCA -0.113
COAD -0.034
HGSC -2.759
ccRCC 0.293
GBM 0.398
HNSC -0.001
LUAD -0.361
LUSC 0.187
non_ccRCC 0.999
PDAC 0.705
UCEC 0.686
TP53BP1-Ser1467
Cancer Intensity
BRCA
COAD 0.052
HGSC -1.961
ccRCC 0.335
GBM
HNSC 0.235
LUAD 0.458
LUSC
non_ccRCC
PDAC
UCEC 0.88
TP53BP1-Ser1479
Cancer Intensity
BRCA 1.04
COAD
HGSC
ccRCC -0.431
GBM
HNSC -0.965
LUAD -0.754
LUSC
non_ccRCC
PDAC
UCEC 1.11
TP53BP1-Ser1485
Cancer Intensity
BRCA
COAD
HGSC -1.145
ccRCC
GBM
HNSC 0.704
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.441
TP53BP1-Ser1486
Cancer Intensity
BRCA
COAD -0.176
HGSC -1.675
ccRCC
GBM 0.676
HNSC 0.499
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.676
TP53BP1-Ser1553
Cancer Intensity
BRCA -0.399
COAD -0.09
HGSC -1.597
ccRCC -0.186
GBM 2.062
HNSC -0.731
LUAD 0.544
LUSC
non_ccRCC -0.011
PDAC
UCEC 0.406
TP53BP1-Ser1570
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC
LUAD 0.707
LUSC
non_ccRCC
PDAC
UCEC -0.707
TP53BP1-Ser1623
Cancer Intensity
BRCA 0.109
COAD 0.706
HGSC -0.313
ccRCC 0.633
GBM -0.649
HNSC -0.116
LUAD -0.594
LUSC -2.106
non_ccRCC
PDAC 1.333
UCEC 0.996
TP53BP1-Ser1636
Cancer Intensity
BRCA 2.069
COAD
HGSC
ccRCC
GBM -0.803
HNSC 0.499
LUAD -0.343
LUSC -0.484
non_ccRCC
PDAC -0.596
UCEC -0.341
TP53BP1-Ser1639
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.707
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.707
TP53BP1-Ser1640
Cancer Intensity
BRCA
COAD 0.48
HGSC -2.197
ccRCC
GBM 0.518
HNSC -0.103
LUAD
LUSC 0.197
non_ccRCC 0.631
PDAC 0.473
UCEC
TP53BP1-Ser1647
Cancer Intensity
BRCA
COAD -0.281
HGSC 1.11
ccRCC -0.829
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1648
Cancer Intensity
BRCA
COAD
HGSC 1.462
ccRCC -0.179
GBM -0.704
HNSC -0.579
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1649
Cancer Intensity
BRCA
COAD -0.509
HGSC 1.152
ccRCC
GBM -0.643
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1650
Cancer Intensity
BRCA
COAD -0.045
HGSC 1.661
ccRCC
GBM -0.557
HNSC -0.1
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.959
TP53BP1-Ser1670
Cancer Intensity
BRCA -1.256
COAD
HGSC
ccRCC
GBM 1.05
HNSC 0.489
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.283
TP53BP1-Ser1678
Cancer Intensity
BRCA -0.443
COAD
HGSC
ccRCC 0.603
GBM
HNSC 0.93
LUAD -1.54
LUSC 0.45
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1683
Cancer Intensity
BRCA -0.772
COAD 0.322
HGSC 1.65
ccRCC -0.051
GBM -0.095
HNSC -0.488
LUAD -1.952
LUSC -0.351
non_ccRCC 1.276
PDAC -0.344
UCEC 0.805
TP53BP1-Ser1691
Cancer Intensity
BRCA
COAD
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser1706
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1710
Cancer Intensity
BRCA -1.394
COAD 0.841
HGSC -0.038
ccRCC
GBM
HNSC 0.59
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1763
Cancer Intensity
BRCA
COAD -0.438
HGSC -0.706
ccRCC
GBM
HNSC 1.144
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1764
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser1976
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser207
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -1.152
GBM
HNSC 0.647
LUAD 0.505
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser213
Cancer Intensity
BRCA
COAD
HGSC -1.494
ccRCC
GBM 0.482
HNSC
LUAD
LUSC 0.615
non_ccRCC
PDAC
UCEC 0.398
TP53BP1-Ser227
Cancer Intensity
BRCA -0.559
COAD 1.032
HGSC -2.558
ccRCC 0.347
GBM 0.449
HNSC -0.102
LUAD -0.028
LUSC 0.4
non_ccRCC -0.468
PDAC 1.106
UCEC 0.381
TP53BP1-Ser264
Cancer Intensity
BRCA
COAD
HGSC 0.99
ccRCC -0.182
GBM
HNSC -0.921
LUAD -0.976
LUSC
non_ccRCC
PDAC
UCEC 1.09
TP53BP1-Ser270
Cancer Intensity
BRCA -1.282
COAD -0.547
HGSC 0.337
ccRCC 0.598
GBM -1.076
HNSC -0.407
LUAD -0.065
LUSC 0.122
non_ccRCC 2.428
PDAC -0.468
UCEC 0.359
TP53BP1-Ser285
Cancer Intensity
BRCA 1.685
COAD
HGSC
ccRCC -0.745
GBM 1.526
HNSC -0.932
LUAD -0.956
LUSC -0.513
non_ccRCC 0.35
PDAC -0.309
UCEC -0.105
TP53BP1-Ser292
Cancer Intensity
BRCA
COAD -1.068
HGSC
ccRCC 0.155
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC 0.914
UCEC
TP53BP1-Ser299
Cancer Intensity
BRCA 0.87
COAD -0.078
HGSC -2.675
ccRCC -0.093
GBM -0.102
HNSC 0.366
LUAD 0.294
LUSC
non_ccRCC 0.809
PDAC 0.331
UCEC 0.278
TP53BP1-Ser306
Cancer Intensity
BRCA 0.988
COAD
HGSC -2.119
ccRCC -0.082
GBM 0.471
HNSC 0.168
LUAD
LUSC
non_ccRCC
PDAC 0.523
UCEC 0.051
TP53BP1-Ser315
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM -0.707
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser320
Cancer Intensity
BRCA
COAD
HGSC -1.367
ccRCC
GBM
HNSC
LUAD 0.823
LUSC -0.12
non_ccRCC
PDAC
UCEC 0.664
TP53BP1-Ser321
Cancer Intensity
BRCA
COAD 0.049
HGSC -1.635
ccRCC
GBM
HNSC
LUAD 1.072
LUSC 0.111
non_ccRCC
PDAC
UCEC 0.404
TP53BP1-Ser328
Cancer Intensity
BRCA
COAD 0.516
HGSC -1.499
ccRCC
GBM
HNSC
LUAD 0.462
LUSC
non_ccRCC
PDAC
UCEC 0.521
TP53BP1-Ser338
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser354
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC
LUAD
LUSC -0.707
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser364
Cancer Intensity
BRCA
COAD 0.056
HGSC -1.97
ccRCC 0.135
GBM
HNSC 0.748
LUAD 0.568
LUSC
non_ccRCC
PDAC
UCEC 0.463
TP53BP1-Ser365
Cancer Intensity
BRCA
COAD 0.194
HGSC -2.17
ccRCC 0.331
GBM 0.514
HNSC 0.459
LUAD -0.134
LUSC
non_ccRCC
PDAC
UCEC 0.807
TP53BP1-Ser371
Cancer Intensity
BRCA
COAD 0.363
HGSC -2.39
ccRCC 0.224
GBM 0.432
HNSC 0.282
LUAD 0.45
LUSC 0.787
non_ccRCC -1.185
PDAC 0.322
UCEC 0.716
TP53BP1-Ser384
Cancer Intensity
BRCA
COAD -0.738
HGSC -1.53
ccRCC 0.308
GBM 0.046
HNSC 1.09
LUAD -0.451
LUSC
non_ccRCC
PDAC
UCEC 1.275
TP53BP1-Ser385
Cancer Intensity
BRCA
COAD -0.386
HGSC -0.687
ccRCC -1.022
GBM 0.177
HNSC 1.595
LUAD
LUSC
non_ccRCC -1.225
PDAC 0.946
UCEC 0.602
TP53BP1-Ser400
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC 0.404
LUAD -1.139
LUSC
non_ccRCC
PDAC
UCEC 0.735
TP53BP1-Ser403
Cancer Intensity
BRCA -0.985
COAD -0.068
HGSC 1.876
ccRCC -0.131
GBM -0.285
HNSC 0.06
LUAD -1.371
LUSC -0.905
non_ccRCC 1.623
PDAC 0.257
UCEC -0.07
TP53BP1-Ser498
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.707
GBM
HNSC
LUAD 0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser505
Cancer Intensity
BRCA -0.037
COAD 0.014
HGSC -2.9
ccRCC 0.331
GBM 0.067
HNSC 0.367
LUAD 0.392
LUSC 0.005
non_ccRCC 0.902
PDAC 0.485
UCEC 0.375
TP53BP1-Ser512
Cancer Intensity
BRCA 1.485
COAD 0.489
HGSC -0.63
ccRCC 0.023
GBM 0.487
HNSC 1.573
LUAD 0.259
LUSC -0.106
non_ccRCC -1.184
PDAC -0.978
UCEC -1.417
TP53BP1-Ser517
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser523
Cancer Intensity
BRCA
COAD
HGSC -0.69
ccRCC 0.759
GBM
HNSC 0.019
LUAD -1.257
LUSC
non_ccRCC
PDAC
UCEC 1.17
TP53BP1-Ser525
Cancer Intensity
BRCA
COAD 0.506
HGSC 0.654
ccRCC 0.077
GBM -2.217
HNSC 0.145
LUAD 0.301
LUSC
non_ccRCC
PDAC
UCEC 0.535
TP53BP1-Ser528
Cancer Intensity
BRCA
COAD -0.171
HGSC -1.639
ccRCC -0.136
GBM 0.779
HNSC -0.185
LUAD -0.644
LUSC 2.069
non_ccRCC 0.763
PDAC -0.411
UCEC -0.425
TP53BP1-Ser530
Cancer Intensity
BRCA -0.036
COAD 0.178
HGSC -1.733
ccRCC 0.596
GBM 0.017
HNSC 0.345
LUAD -1.451
LUSC -0.164
non_ccRCC 2.072
PDAC 0.245
UCEC -0.069
TP53BP1-Ser535
Cancer Intensity
BRCA
COAD
HGSC 1.018
ccRCC
GBM -0.981
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.037
TP53BP1-Ser537
Cancer Intensity
BRCA
COAD
HGSC 0.707
ccRCC
GBM -0.707
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser557
Cancer Intensity
BRCA 0.648
COAD -0.154
HGSC -2.781
ccRCC 0.241
GBM -0.252
HNSC 0.948
LUAD -0.18
LUSC 0.094
non_ccRCC 0.681
PDAC 0.458
UCEC 0.296
TP53BP1-Ser571
Cancer Intensity
BRCA -0.576
COAD 1.754
HGSC -0.006
ccRCC -0.236
GBM -1.184
HNSC 0.071
LUAD -0.992
LUSC -0.507
non_ccRCC 0.32
PDAC 1.875
UCEC -0.519
TP53BP1-Ser585
Cancer Intensity
BRCA 0.535
COAD -1.562
HGSC -1.703
ccRCC 0.742
GBM -0.353
HNSC -0.287
LUAD -0.472
LUSC 0.187
non_ccRCC 1.433
PDAC 1.064
UCEC 0.415
TP53BP1-Ser603
Cancer Intensity
BRCA
COAD
HGSC 1.323
ccRCC -0.58
GBM -0.26
HNSC
LUAD
LUSC -1.028
non_ccRCC -0.475
PDAC 1.521
UCEC -0.501
TP53BP1-Ser635
Cancer Intensity
BRCA
COAD
HGSC -1.368
ccRCC -0.486
GBM 1.411
HNSC 0.686
LUAD
LUSC
non_ccRCC 0.327
PDAC
UCEC -0.57
TP53BP1-Ser640
Cancer Intensity
BRCA -0.305
COAD
HGSC -1.283
ccRCC
GBM
HNSC
LUAD 0.827
LUSC
non_ccRCC
PDAC
UCEC 0.76
TP53BP1-Ser644
Cancer Intensity
BRCA -1.334
COAD 0.02
HGSC -1.641
ccRCC -0.056
GBM 0.081
HNSC 0.04
LUAD 0.851
LUSC
non_ccRCC
PDAC 1.617
UCEC 0.421
TP53BP1-Ser645
Cancer Intensity
BRCA -1.351
COAD 0.124
HGSC -1.73
ccRCC -0.073
GBM 0.456
HNSC 0.134
LUAD 0.53
LUSC
non_ccRCC
PDAC 1.6
UCEC 0.31
TP53BP1-Ser664
Cancer Intensity
BRCA -1.928
COAD
HGSC
ccRCC 0.231
GBM -1.015
HNSC 0.184
LUAD 0.689
LUSC
non_ccRCC 0.698
PDAC 0.045
UCEC 1.095
TP53BP1-Ser665
Cancer Intensity
BRCA -1.928
COAD
HGSC
ccRCC 0.231
GBM -1.015
HNSC 0.184
LUAD 0.689
LUSC
non_ccRCC 0.698
PDAC 0.045
UCEC 1.095
TP53BP1-Ser667
Cancer Intensity
BRCA -1.933
COAD
HGSC
ccRCC 0.323
GBM -1.024
HNSC 0.17
LUAD 0.673
LUSC
non_ccRCC 0.682
PDAC 0.032
UCEC 1.078
TP53BP1-Ser679
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.707
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser68
Cancer Intensity
BRCA 0.987
COAD -2.012
HGSC -1.715
ccRCC 0.437
GBM 0.453
HNSC -0.118
LUAD -0.346
LUSC 0.676
non_ccRCC 0.387
PDAC 0.38
UCEC 0.871
TP53BP1-Ser697
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC -0.055
LUAD -1.182
LUSC 1.264
non_ccRCC -0.027
PDAC
UCEC
TP53BP1-Ser718
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 0.707
GBM
HNSC -0.707
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser726
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.447
GBM 1.442
HNSC 0.504
LUAD -0.336
LUSC
non_ccRCC
PDAC
UCEC -1.163
TP53BP1-Ser729
Cancer Intensity
BRCA
COAD -0.13
HGSC -2.257
ccRCC 0.179
GBM -0.219
HNSC 0.587
LUAD 0.141
LUSC 0.884
non_ccRCC
PDAC
UCEC 0.814
TP53BP1-Ser732
Cancer Intensity
BRCA -0.208
COAD 0.142
HGSC -2.711
ccRCC 0.191
GBM -0.037
HNSC 0.05
LUAD 0.206
LUSC 0.05
non_ccRCC 0.327
PDAC 1.45
UCEC 0.541
TP53BP1-Ser770
Cancer Intensity
BRCA 0.423
COAD
HGSC
ccRCC -0.747
GBM
HNSC
LUAD -0.37
LUSC
non_ccRCC -0.983
PDAC 1.775
UCEC -0.098
TP53BP1-Ser776
Cancer Intensity
BRCA 0.271
COAD 0.765
HGSC -2.79
ccRCC 0.158
GBM -0.191
HNSC -0.218
LUAD 0.138
LUSC -0.044
non_ccRCC 0.472
PDAC 1.01
UCEC 0.428
TP53BP1-Ser787
Cancer Intensity
BRCA
COAD -0.707
HGSC
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Ser789
Cancer Intensity
BRCA
COAD -0.416
HGSC -0.725
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 1.141
TP53BP1-Ser791
Cancer Intensity
BRCA
COAD -0.396
HGSC -0.758
ccRCC -0.504
GBM -0.548
HNSC
LUAD -0.418
LUSC
non_ccRCC 0.571
PDAC
UCEC 2.053
TP53BP1-Ser814
Cancer Intensity
BRCA 1.193
COAD 0.263
HGSC -1.342
ccRCC 0.174
GBM 0.512
HNSC -0.612
LUAD 0.029
LUSC -1.749
non_ccRCC 1.038
PDAC 1.19
UCEC -0.696
TP53BP1-Ser83
Cancer Intensity
BRCA -1.09
COAD
HGSC 0.998
ccRCC
GBM 0.683
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.591
TP53BP1-Ser835
Cancer Intensity
BRCA
COAD 0.165
HGSC -2.217
ccRCC 0.396
GBM 0.155
HNSC 0.71
LUAD 0.221
LUSC
non_ccRCC
PDAC
UCEC 0.57
TP53BP1-Ser836
Cancer Intensity
BRCA -0.736
COAD 0.068
HGSC -2.686
ccRCC 0.772
GBM 0.974
HNSC 0.564
LUAD 0.065
LUSC 0.48
non_ccRCC 0.333
PDAC -0.008
UCEC 0.173
TP53BP1-Ser839
Cancer Intensity
BRCA -0.583
COAD -0.188
HGSC -2.68
ccRCC 1.035
GBM 0.581
HNSC 0.651
LUAD 0.173
LUSC 0.34
non_ccRCC 0.331
PDAC -0.215
UCEC 0.556
TP53BP1-Ser865
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.191
GBM 0.78
HNSC 0.126
LUAD -1.599
LUSC
non_ccRCC
PDAC
UCEC 0.885
TP53BP1-Ser867
Cancer Intensity
BRCA -0.274
COAD -0.662
HGSC -2.153
ccRCC 0.879
GBM 1.09
HNSC 0.043
LUAD -0.521
LUSC -0.128
non_ccRCC
PDAC 0.631
UCEC 1.096
TP53BP1-Ser872
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Ser980
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 0.791
HNSC -1.124
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.333
TP53BP1-Thr1060
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM 1.029
HNSC -0.968
LUAD
LUSC
non_ccRCC
PDAC
UCEC -0.062
TP53BP1-Thr1061
Cancer Intensity
BRCA
COAD -0.269
HGSC -0.937
ccRCC
GBM 1.254
HNSC -0.884
LUAD 0.836
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1127
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1297
Cancer Intensity
BRCA
COAD -0.984
HGSC
ccRCC
GBM 1.016
HNSC -0.032
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1324
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1377
Cancer Intensity
BRCA
COAD
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.707
TP53BP1-Thr1547
Cancer Intensity
BRCA
COAD
HGSC -0.366
ccRCC 1.421
GBM
HNSC -0.908
LUAD -0.148
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1550
Cancer Intensity
BRCA
COAD 0.132
HGSC
ccRCC 0.349
GBM 1.279
HNSC -1.462
LUAD -0.298
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr1614
Cancer Intensity
BRCA -1.431
COAD 0.67
HGSC -0.485
ccRCC -0.788
GBM 2.021
HNSC 0.49
LUAD 0.36
LUSC -1.166
non_ccRCC -0.522
PDAC 0.109
UCEC 0.741
TP53BP1-Thr1643
Cancer Intensity
BRCA 0.854
COAD 0.392
HGSC -2.863
ccRCC -0.177
GBM 0.33
HNSC -0.216
LUAD 0.109
LUSC 0.262
non_ccRCC 0.662
PDAC 0.352
UCEC 0.295
TP53BP1-Thr1645
Cancer Intensity
BRCA
COAD
HGSC 1.376
ccRCC -0.165
GBM
HNSC -0.191
LUAD
LUSC
non_ccRCC
PDAC
UCEC -1.021
TP53BP1-Thr1677
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 0.498
GBM
HNSC 0.653
LUAD -1.151
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr210
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.953
GBM -0.14
HNSC 1.405
LUAD -0.312
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr307
Cancer Intensity
BRCA 1.201
COAD
HGSC -1.731
ccRCC -0.4
GBM 0.405
HNSC
LUAD
LUSC
non_ccRCC
PDAC 0.485
UCEC 0.041
TP53BP1-Thr326
Cancer Intensity
BRCA
COAD 0.178
HGSC -1.077
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC 0.899
TP53BP1-Thr339
Cancer Intensity
BRCA
COAD
HGSC -1.059
ccRCC
GBM
HNSC
LUAD 0.928
LUSC
non_ccRCC
PDAC
UCEC 0.131
TP53BP1-Thr362
Cancer Intensity
BRCA
COAD -0.707
HGSC
ccRCC -1.347
GBM 0.87
HNSC 0.983
LUAD -0.585
LUSC
non_ccRCC
PDAC
UCEC 0.787
TP53BP1-Thr387
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr514
Cancer Intensity
BRCA
COAD -1.013
HGSC
ccRCC
GBM
HNSC
LUAD 0.987
LUSC
non_ccRCC
PDAC
UCEC 0.026
TP53BP1-Thr524
Cancer Intensity
BRCA
COAD
HGSC -1.647
ccRCC 1.11
GBM 0.732
HNSC 0.067
LUAD -0.62
LUSC
non_ccRCC
PDAC
UCEC 0.358
TP53BP1-Thr548
Cancer Intensity
BRCA
COAD -0.553
HGSC
ccRCC -0.852
GBM -1.152
HNSC 1.36
LUAD -0.873
LUSC
non_ccRCC 1.18
PDAC 0.793
UCEC 0.098
TP53BP1-Thr553
Cancer Intensity
BRCA -0.948
COAD -0.216
HGSC 2.491
ccRCC -0.337
GBM -0.276
HNSC -0.039
LUAD -0.644
LUSC
non_ccRCC
PDAC 0.332
UCEC -0.364
TP53BP1-Thr596
Cancer Intensity
BRCA -1.264
COAD
HGSC 0.457
ccRCC 1.146
GBM 0.685
HNSC
LUAD -1.219
LUSC -0.575
non_ccRCC
PDAC
UCEC 0.77
TP53BP1-Thr598
Cancer Intensity
BRCA
COAD 0.967
HGSC 0.99
ccRCC 0.746
GBM
HNSC
LUAD -0.811
LUSC -0.748
non_ccRCC
PDAC
UCEC -1.145
TP53BP1-Thr625
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.906
GBM
HNSC 1.073
LUAD -0.167
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr675
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 0.98
GBM 0.038
HNSC -1.019
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr725
Cancer Intensity
BRCA
COAD
HGSC -1.498
ccRCC 0.475
GBM
HNSC 0.571
LUAD 0.452
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr860
Cancer Intensity
BRCA
COAD
HGSC 1.149
ccRCC -0.674
GBM
HNSC
LUAD
LUSC -0.475
non_ccRCC
PDAC
UCEC
TP53BP1-Thr924
Cancer Intensity
BRCA
COAD 0.049
HGSC 0.024
ccRCC -1.129
GBM 1.767
HNSC -0.772
LUAD 0.06
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Thr927
Cancer Intensity
BRCA 0.42
COAD -0.541
HGSC 1.114
ccRCC -0.931
GBM -1.874
HNSC -1.072
LUAD 0.146
LUSC 0.75
non_ccRCC 1.404
PDAC 0.431
UCEC 0.152
TP53BP1-Tyr1610
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 1.408
GBM
HNSC -0.86
LUAD -0.528
LUSC
non_ccRCC
PDAC
UCEC -0.02
TP53BP1-Tyr209
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.81
GBM -0.249
HNSC 1.457
LUAD -0.399
LUSC
non_ccRCC
PDAC
UCEC
TP53BP1-Tyr527
Cancer Intensity
BRCA
COAD
HGSC
ccRCC 0.475
GBM 0.028
HNSC -0.762
LUAD -1.128
LUSC
non_ccRCC
PDAC
UCEC 1.386
TP53BP1-Tyr817
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP2-Ser302
Cancer Intensity
BRCA -1.124
COAD
HGSC
ccRCC -0.566
GBM -0.494
HNSC
LUAD 0.091
LUSC 0.149
non_ccRCC 0.005
PDAC 2.247
UCEC -0.308
TP53BP2-Ser464
Cancer Intensity
BRCA 0.527
COAD
HGSC -2.253
ccRCC -0.128
GBM
HNSC 0.072
LUAD -0.304
LUSC 0.592
non_ccRCC 0.56
PDAC 0.933
UCEC
TP53BP2-Ser486
Cancer Intensity
BRCA 1.276
COAD 0.133
HGSC -0.092
ccRCC 0.2
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC -1.518
TP53BP2-Ser487
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP2-Ser562
Cancer Intensity
BRCA
COAD 0.933
HGSC -1.471
ccRCC
GBM
HNSC 0.591
LUAD 0.528
LUSC
non_ccRCC -0.582
PDAC
UCEC
TP53BP2-Ser564
Cancer Intensity
BRCA
COAD 0.707
HGSC -0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP2-Ser567
Cancer Intensity
BRCA
COAD
HGSC
ccRCC
GBM
HNSC 0.707
LUAD -0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53BP2-Ser575
Cancer Intensity
BRCA
COAD
HGSC -2.416
ccRCC
GBM 0.138
HNSC 0.568
LUAD 0.429
LUSC 0.408
non_ccRCC -0.08
PDAC 0.404
UCEC 0.549
TP53BP2-Ser578
Cancer Intensity
BRCA 1.05
COAD
HGSC
ccRCC
GBM
HNSC
LUAD -0.11
LUSC -0.941
non_ccRCC
PDAC
UCEC
TP53BP2-Ser582
Cancer Intensity
BRCA -0.722
COAD
HGSC 2.745
ccRCC -0.233
GBM -0.056
HNSC -0.16
LUAD -0.307
LUSC -0.097
non_ccRCC -0.8
PDAC -0.03
UCEC -0.34
TP53BP2-Ser704
Cancer Intensity
BRCA
COAD 0.146
HGSC 2.094
ccRCC -0.259
GBM -0.32
HNSC 0.017
LUAD
LUSC
non_ccRCC
PDAC -0.921
UCEC -0.758
TP53BP2-Ser720
Cancer Intensity
BRCA -1.018
COAD
HGSC -1.714
ccRCC 0.383
GBM -0.221
HNSC 0.064
LUAD 0.02
LUSC 0.356
non_ccRCC 2.135
PDAC 0.262
UCEC -0.267
TP53BP2-Ser742
Cancer Intensity
BRCA
COAD -0.707
HGSC
ccRCC
GBM 0.707
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53BP2-Ser743
Cancer Intensity
BRCA
COAD -0.207
HGSC 0.596
ccRCC -0.287
GBM 0.08
HNSC -1.59
LUAD
LUSC 1.409
non_ccRCC
PDAC
UCEC
TP53BP2-Ser789
Cancer Intensity
BRCA
COAD
HGSC -1.164
ccRCC
GBM 0.336
HNSC 0.998
LUAD
LUSC -0.714
non_ccRCC
PDAC -0.697
UCEC 1.241
TP53BP2-Thr573
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -1.078
GBM
HNSC 1.195
LUAD -0.506
LUSC
non_ccRCC
PDAC
UCEC 0.389
TP53BP2-Thr592
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.237
GBM
HNSC
LUAD -0.622
LUSC
non_ccRCC 1.718
PDAC -0.773
UCEC -0.085
TP53BP2-Thr745
Cancer Intensity
BRCA
COAD
HGSC
ccRCC -0.707
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC 0.707
UCEC
TP53I11-Ser14
Cancer Intensity
BRCA -1.268
COAD 0.477
HGSC 1.815
ccRCC 0.355
GBM -0.192
HNSC 0.761
LUAD -0.233
LUSC 0.795
non_ccRCC -1.777
PDAC -0.274
UCEC -0.459
TP53I11-Ser20
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53I11-Ser45
Cancer Intensity
BRCA -0.707
COAD
HGSC
ccRCC
GBM
HNSC
LUAD 0.707
LUSC
non_ccRCC
PDAC
UCEC
TP53I11-Thr16
Cancer Intensity
BRCA
COAD -0.707
HGSC 0.707
ccRCC
GBM
HNSC
LUAD
LUSC
non_ccRCC
PDAC
UCEC
TP53INP2-Ser14
Cancer Intensity
BRCA
COAD 1.043
HGSC
ccRCC
GBM
HNSC 0.065
LUAD
LUSC 0.25
non_ccRCC
PDAC
UCEC -1.358

PTM-Disease Association:

source: PTMD
Residue Position State Disease Class PMID
S 15 A Breast cancer/tumor/carcinoma Phosphorylation 23798621
S 15 D Ataxia-telangiectasia Phosphorylation 9733515
S 15 D Brain cancer Phosphorylation 23268709
S 15 D Breast cancer/tumor/carcinoma Phosphorylation 15958581
S 15 P Prostate cancer/carcinoma/adenocarcinoma Phosphorylation 23359208
S 15 U Down syndrome Phosphorylation 20696760
S 15 U Hepatocellular carcinoma Phosphorylation 22030623
S 15 U Neuroblastoma Phosphorylation 23824039
S 15 U Colorectal cancer Phosphorylation 25860929

State Note: Based on the distinct PTM states in diseases, PTMD classified all disease-associated PTMs into six classes, including whether the up-regulation (U) or down-regulation (D) of PTM levels, the absence (A) or presence (P) of PTMs, and the creation (C) or disruption (N) of PTM sites are associated with diseases.

PTM-Drug Perturbation Response:

source: DecryptM

No data.

Function score:

source: funscoR

No data.

Cross Links: